Elevated osteopontin and thrombospondin expression identifies malignant human breast carcinoma but is not indicative of metastatic status

Breast Cancer Research

Volumn 5, Issue 5, 2003, Pages

  Wang Rodriguez, Jessica ^a,b   Urquidi, Virginia ^a,b   Rivard, Amber ^a   Goodison, Steve ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

breast carcinoma; immunohistochemistry; metastasis; microdissection; quantitative PCR

Indexed keywords

MEMBRANE PROTEIN; MONOPHENOL MONOOXYGENASE; OSTEOPONTIN; OXIDOREDUCTASE; PROTEIN; SIALOGLYCOPROTEIN; SPP1 PROTEIN, HUMAN; THROMBOSPONDIN 1; TUMOR MARKER; TYROSINASE RELATED PROTEIN; TYROSINASE-RELATED PROTEIN; TYRP1 PROTEIN, HUMAN;

ARTICLE; BIOSYNTHESIS; BREAST TUMOR; CHEMISTRY; COMPARATIVE STUDY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; LASER; LYMPH NODE METASTASIS; METHODOLOGY; PAGET NIPPLE DISEASE; PATHOLOGY; POLYMERASE CHAIN REACTION; PROTEIN SYNTHESIS;

BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; LASERS; LYMPHATIC METASTASIS; MEMBRANE GLYCOPROTEINS; MONOPHENOL MONOOXYGENASE; OSTEOPONTIN; OXIDOREDUCTASES; POLYMERASE CHAIN REACTION; PROTEIN BIOSYNTHESIS; PROTEINS; SIALOGLYCOPROTEINS; THROMBOSPONDIN 1; TUMOR MARKERS, BIOLOGICAL;

EID: 0141462829     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr620     Document Type: Article

References (35)

1. L.A.G. Ries M.P. Eisner C.L. Kosary B.F. Hankey B.A. Miller L. Clegg A. Mariotto M.P. Fay E.J. Feuer B.K. Edwards SEER Cancer Statistics Review, 1975–2000 2003 Bethesda, MD National Cancer Institute http://seer.cancer.gov/csr/1975_2000
2. V. Urquidi K. Kawai D. Agarwal A.C. Woodman D. Tarin S. Goodison Contrasting expression of thrombospondin-1 and osteopontin correlates with absence or presence of metastatic phenotype in an isogenic model of spontaneous human breast cancer metastasis Clin Cancer Res 2002 8 61 74 1:CAS:528:DC%2BD38XhsVKmtL4%3D 11801541
3. A. Tuck D. Arsenault F. O'Malley C. Hota M. Ling S. Wilson A. Chambers Osteopontin indices increased invasiveness and plasminogen activator expression of human mammary epithelial cells Oncogene 1999 18 4237 4246 1:CAS:528:DyaK1MXlt1OlsLs%3D 10.1038/sj.onc.1202799 10435636
4. J. Lawler The functions of thrombospondin-1 and -2 Curr Opin Cell Biol 2000 12 634 640 1:CAS:528:DC%2BD3cXms1Chur4%3D 10.1016/S0955-0674(00)00143-5 10978901
5. D. Agarwal S. Goodison B. Nicholson D. Tarin V. Urquidi Expression of matrix metalloproteinase 8 (MMP-8) and tyrosinase-related protein-1 (TYRP-1) correlates with the absence of metastasis in an Isogenic Human Breast Cancer Model Differentiation 2002 71 114 125 10.1046/j.1432-0436.2003.710202.x
6. D. Denhardt C. Lopez E. Rollo S. Hwang X. An S. Walther Osteopontin-induced modifications of cellular functions Ann NY Acad Sci 1995 760 127 142 1:CAS:528:DyaK2MXovVSisbY%3D 10.1111/j.1749-6632.1995.tb44625.x 7540371
7. Q. Ding J.J. Stewart C. Prince P. Chang M. Trikha X. Han J. Grammer C. Gladson Promotion of malignant astrocytoma cell migration by osteopontin expressed in the normal brain: differences in integrin signaling during cell adhesion to osteopontin versus vitronectin Cancer Res 2002 62 5336 5343 1:CAS:528:DC%2BD38Xnt1ynsbY%3D 12235004
8. D. Senger C. Perruzzi C. Gracey A. Papadopoulos D. Tenen Secreted phosphoproteins associated with neoplastic transformation: close homology with plasma proteins cleaved during blood coagulation Cancer Res 1988 48 5770 5774 1:CAS:528:DyaL1cXmtV2jsbw%3D 3167835
9. H. Singhal D. Bautista K. Tonkin F. O'Malley A. Tuck A.H. Chambers J.F.R. Harris Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival Clin Cancer Res 1997 3 605 611 1:STN:280:DyaK1M%2FjsFehtQ%3D%3D 9815727
10. P. Bornstein Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1 J Cell Biol 1995 130 503 506 1:CAS:528:DyaK2MXntFWhtLs%3D 10.1083/jcb.130.3.503 7542656
11. F. Reiher O. Volpert B. Jimenex S. Crawford C. Dinney J. Henkin F. Haviv N. Bouck S. Campbell Inhibition of tumor growth by systemic treatment with thrombospondin-1 peptide mimetics Int J Cancer 2002 98 682 689 1:CAS:528:DC%2BD38Xis1Wrurg%3D 10.1002/ijc.10247 11920636
12. G. Gasparini M. Toi E. Biganzoli R. Dittadi M. Ranelli A. Morabito P. Boracchi M. Gion Thrombospondin-1 and -2 in node-negative breast cancer: correlation with angiogenic factors, p52, cathepsin D, hormone receptors and prognosis Oncology 2001 60 72 80 1:STN:280:DC%2BD3M7hvVSgsQ%3D%3D 10.1159/000055300 11150912
13. A. Tuck F. O'Malley H. Singhal J. Harris K. Tonkin N. Kerkvliet Z. Saad G. Doig A. Chambers Osteopontin expression in a group of lymph node negative breast cancer patients Int J Cancer 1998 79 502 508 1:CAS:528:DyaK1cXmsVWju7w%3D 10.1002/(SICI)1097-0215(19981023)79:5<502::AID-IJC10>3.0.CO;2-3 9761120
14. T. Wang D. Albo G. Tuszynski Fibroblasts promote breast cancer cell invasion by upregulating tumor matrix metalloproteinase-9 production Surgery 2002 132 220 225 10.1067/msy.2002.125353 12219015
15. L. Brown A. Papadopoulous-Sergiou B. Berse E. Manseau K. Tognazzi C. Perruzzi H. Dvorak D. Senger Osteopontin expression and distribution in human carcinomas Am J Pathol 1994 145 610 623 1:STN:280:DyaK2czmtFajug%3D%3D 8080043 1890312
16. Y.-T. Chen E. Stockert S. Tsang D. Copland L. Old Immunophenotyping of melanomas for tyrosinase: implications for vaccine development Proc Natl Acad Sci USA 1995 93 8125 8129 10.1073/pnas.92.18.8125
17. E.W. Elston I.O. Ellis Pathological prognostic factors in breast cancer. I The value of histological grade in breast cancer: experience from a large study with long-term follow-up Histopathology 1991 19 403 410 1:STN:280:DyaK38%2FpvVSltw%3D%3D 10.1111/j.1365-2559.1991.tb00229.x 1757079
18. N. Simone R. Bonner J. Gillespie M. Emmert-Buck L. Liotta Laser-capture microdissection: opening the microscopic frontier to molecular analysis Trends Genet 1998 14 272 276 1:CAS:528:DyaK1cXks1Gisrs%3D 10.1016/S0168-9525(98)01489-9 9676529
19. D. Bautista J. Xuan C. Hota A. Chambers J. Harris Inhibition of Arg-Gly-Asp (RGD)-mediated cell adhesion to osteopontin by a monoclonal antibody against osteopontin J Biol Chem 1994 269 23280 23285 1:CAS:528:DyaK2cXlslKntr0%3D 8083234
20. V. Sung C. Gilles A. Murray R. Clarke A. Aaron N. Azumi E. Thompson The LCC15-MB human breast cancer cell line expresses osteopontin and exhibits an invasive and metastatic phenotype Exp Cell Res 1998 241 273 284 1:CAS:528:DyaK1cXktVShsbg%3D 10.1006/excr.1998.4029 9637769
21. A. Oates R. Barraclough P. Rudland The identification of osteopontin as a metastasis-related gene product in a rodent mammary tumour model Oncogene 1996 13 97 104 1:CAS:528:DyaK28Xks1ens7g%3D 8700559
22. E. Behrend A. Craig S. Wilson D. Denhardt A. Chambers Reduced malignancy of ras-transformed NIH 3T3 cells expressing antisense osteopontin RNA Cancer Res 1994 54 832 837 1:CAS:528:DyaK2cXhs1Sgsb8%3D 8306346
23. H. Gardner B. Berse D. Senger Specific reduction in osteopontin synthesis by antisense RNA inhibits the tumorigenicity of transformed Rat1 fibroblasts Oncogene 1994 9 2321 2326 1:STN:280:DyaK2czgvF2jug%3D%3D 8036014
24. S. Hirota A. Ito J. Nagoshi M. Takeda A. Kurata Y. Takatsuka K. Kohri S. Nomura Y. Kitamura Expression of bone matrix protein messenger ribonucleic acids in human breast cancers. Possible involvement of osteopontin in development of calcifying foci Lab Invest 1995 72 64 69 1:CAS:528:DyaK2MXltFChtbk%3D 7837792
25. P. Rudland A. Platt-Higgins M. El-Tanani S. Rudland R. Barraclough J. Winstanley R. Howit C. West Prognostic significance of the metastasis-associated protein Osteopontin in human breast cancer Cancer Res 2002 62 3417 3427 1:CAS:528:DC%2BD38XkslWqsb0%3D 12067984
26. D. Weinstat-Saslow V. Zabrenetzky K. VanHoutte W. Frazier D. Roberts P. Steeg Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis Cancer Res 1994 54 6504 6511 1:CAS:528:DyaK2MXislalsLo%3D 7527299
27. O. Volpert J. Lawler N. Bouck A human fibrosarcoma inhibits systemic angiogenesis and the growth of experimental metastases via thrombospondin-1 Proc Natl Acad Sci USA 1998 95 6343 6348 1:CAS:528:DyaK1cXjtlKgt7Y%3D 10.1073/pnas.95.11.6343 9600967 27689
28. K. Tobita H. Kijima S. Dowaki Y. Oida H. Kashiwagi M. Ishii Y. Sugio T. Sekka Y. Ohtani M. Tanaka S. Inokuchi H. Makuuchi Thrombospondin-1 expression as a prognostic predictor of pancreatic ductal carcinoma Int J Oncol 2002 21 1189 1195 1:CAS:528:DC%2BD38XpsVygtb4%3D 12429967
29. J. Goddard C. Sutton J. Jones K. O'Byrne R. Kockelbergh Reduced thrombospondin-1 at presentation predicts disease progression in superficial bladder cancer Eur Urol 2002 42 464 468 10.1016/S0302-2838(02)00372-X 12429155
30. A. Rice M. Steward C. Quinn Thrombospondin 1 protein expression relates to good prognostic indices in ductal carcinoma in situ of the breast J Clin Pathol 2002 55 921 925 1:STN:280:DC%2BD38jivFSntA%3D%3D 10.1136/jcp.55.12.921 12461058 1769827
31. D. Albo T. Shinohara G. Tuszynski Up-regulation of matrix metalloproteinase 9 by thrombospondin 1 in gastric cancer J Surg Res 1995 108 51 60 10.1006/jsre.2002.6452
32. T. de Vries D. Trancikova D. Ruiter G. van Muijen High expression of immunotherapy candidate proteins gp100, MART-1, tyrosinase and TRP-1 in uveal melanoma Br J Cancer 1998 78 1156 1161 1:CAS:528:DyaK1cXntlSqs7k%3D 10.1038/bjc.1998.646 9820172 2063001
33. N. de Wit H. Burtscher U. Weidle D. Ruiter G. van Muijen Differentially expressed genes identified in human melanoma cell lines with different metastatic behavior using high density oligonucleotide arrays Melanoma Res 2002 12 57 69 1:CAS:528:DC%2BD38XitVCms70%3D 10.1097/00008390-200202000-00009 11828259
34. D. Fang J. Hallman N. Sangha T. Kute J. Hammarback W. White V. Setaluri Expression of microtubule-associated protein 2 in benign and malignant melanocytes: implications for differentiation and progression of cutaneous melanoma Am J Pathol 2001 158 2107 2115 1:CAS:528:DC%2BD3MXkvFyksbg%3D 10.1016/S0002-9440(10)64682-2 11395388 1892002
35. D. Rubin E. Rubin The possible role of tyrosinase in malignant growth Met Hypotheses 1983 10 469 471 1:STN:280:DyaL3s3ntVynuw%3D%3D 10.1016/0306-9877(83)90014-2