Bacterial toxins as mucosal adjuvants

Current Topics in Microbiology and Immunology

Volumn 236, Issue , 1999, Pages 215-236

  Freytag, L C ^a   Clements, J D ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; CD8 ANTIGEN; CHOLERA TOXIN; ENTEROTOXIN; GAMMA INTERFERON; HEAT LABILE ENTEROTOXIN; INTERLEUKIN 2; INTERLEUKIN 4; UNCLASSIFIED DRUG;

ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; DRUG MECHANISM; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; INTESTINE MUCOSA PERMEABILITY; LYMPHOCYTOSIS; PRIORITY JOURNAL; REVIEW; SALMONELLA;

ANIMALIA; BACTERIA (MICROORGANISMS); SALMONELLA;

EID: 0032889806     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-59951-4_11     Document Type: Review

References (10)

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2. Brown W, Woods V, Chitko-McKown C, Hash S, Rice-Ficht A (1994) Interleukin-10 is expressed by bovine type 1 helper, type 2 helper,and unrestricted parasite-specific T-cell clones and inhibits proliferation of all three subsets in an accessory-cell-dependent manner. Infect Immun 62:4697-4708
3. Burnette WN, Mar VL, Platler BW, Schlotterbeck JD, McGinley MD, Stoney KS, Rhode MF, Kaslow HR (1991) Site-specific mutagenesis of the catalytic subunit of cholera toxin: substituting lysine for arginine 7 causes loss of activity. Infect Immun 59:4266-4270
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8. Clements JD, Hartzog NM, Lyon FL (1988) Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens. Vaccine 6:269-277
9. Dickinson BL, Clements JD (1995) Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity. Infect Immun 63:1617-1623
10. DiTommaso A, Saletti G, Pizza M, Rappuoli R, Dougan G, Abrignani S, Douce G, DeMagistris MT (1996) Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant. Infect Immun 64:974-979