Early events associated to the oral co-administration of type II collagen and chitosan: Induction of anti-inflammatory cytokines

International Immunology

Volumn 16, Issue 3, 2004, Pages 433-441

  Porporatto, Carina ^a   Bianco, Ismael D ^b   Cabanillas, Ana M ^a   Correa, Silvia G ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

^b Centro de Excelencia en Productos y Procesos de Cordoba   (Argentina)

Author keywords

Chitosan; Collagen; Cytokine; Oral tolerance; Transforming growth factor

Indexed keywords

ANTIGEN; CD3 ANTIGEN; CHITOSAN; COLLAGEN TYPE 2; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 2; MESSENGER RNA; POLYSACCHARIDE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEEDING; FEMALE; GASTROINTESTINAL ABSORPTION; GASTROINTESTINAL MUCOSA; GENE INDUCTION; IMMUNE SYSTEM; IMMUNOLOGICAL TOLERANCE; INTERNALIZATION; LYMPHOCYTE COUNT; LYMPHOID TISSUE; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; RAT; SPLEEN CELL; T LYMPHOCYTE ACTIVATION;

ADMINISTRATION, ORAL; ANIMALS; ANTIGENS, CD3; CELL DEATH; CHITIN; CHITOSAN; COLLAGEN TYPE II; CYTOKINES; FEMALE; GENE EXPRESSION; IMMUNITY, MUCOSAL; INTERLEUKIN-10; INTERLEUKIN-2; PEPSIN A; PEYER'S PATCHES; RATS; RATS, WISTAR; RNA, MESSENGER; SPLEEN; T-LYMPHOCYTES;

EID: 1542359555     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxh051     Document Type: Article

References (46)

1. Muzzarelli, R. A. 1993. Biomedical significance of exogenous chitins in animals and patients. Carbohydr. Polym. 20:7.
2. Ilium, L., Jabbal-Gill, I., Hinchcliffe, M., Fisher, A. N. and Davis, S. S. 2001. Chitosan as a novel nasal delivery system for vaccines. Adv. Drug Deliv. Rev. 51:81.
3. Thanou, M., Verhoef, J. C. and Junginger, H. E. 2001. Oral drug absorption enhancement by chitosan and its derivatives. Adv. Drug Deliv. Rev. 52:117.
4. van del Lubben, I. M., Verhoef, J. C., Borchard, G. and Junginger, H. E. 2001. Chitosan for mucosal vaccination. Adv. Drug Deliv. Rev. 52:139.
5. Artursson, P., Lindmark, T., Davis, S. S. and Illum, L. 1994. Effect of chitosan on the permeability of monolayers of intestinal epithelial cell (Caco-2). Pharm. Res. 11:1358.
6. Dodane, V., Khan, A. M. and Merwin, J. R. 1999. Effect of chitosan on epithelial permeability and structure. Int. J. Pharm. 182:21.
7. Schipper, N. G. M., Olsson, S., Hoogstraate, J. A., de Boer, A. G., Vårum, K. M. and Artursson, P. 1997. Chitosans as absorption enhancers for poorly absorbable drugs 2: mechanism of absorption enhancement. Pharm. Res. 14:923.
8. Weiner, H. L. 1997. Oral tolerance: immune mechanisms and treatment of autoimmune diseases. Immunol. Today 18:335.
9. Strobel, S. and Mowat, A. M. 1998. Immune response to dietary antigens: oral tolerance. Immunol. Today 19:1173.
10. Kjær, T. M. R. and Froklær, H. 2002. Induction of oral tolerance with micro-doses of ovomucoid depends on the length of the feeding period. Scand. J. Immunol. 55:359.
11. h1 immune responses in human Peyer's patches. Trends Immunol. 22:244.
12. H3 regulatory cells. Nat. Immunol. 2:671.
13. Kalden J. R. and Sieper, J. 1998. Oral collagen in the treatment of rheumatoid arthritis. Arthritis Rheum. 41:191.
14. Postlethwaite, A. E. 2001. Can we induce tolerance in rheumatoid arthritis? Curr. Rheumatol. Rep. 3:64.
15. Diamond, B., Bluestone, J. and Wofsy, D. 2001. The immune tolerance network and rheumatic disease. Arthritis Rheum. 44:1730.
16. Taravel, M. N. and Domard, A. 1993. Relation between the physicochemical characteristics of collagen and its interactions with chitosan. I. Biomaterials 14:930.
17. Taravel, M. N. and Domard, A. 1995. Collagen and its interaction with chitosan. II. Influence of the physicochemical characteristics of collagen. Biomaterials 16:865.
18. Taravel, M. N. and Domard, A. 1996. Collagen and its interactions with chitosan. III. Some biological and mechanical properties. Biomaterials 17:451.
19. Trentham, D. E., Townes, A. S. and Kand, A. H. 1977. Autoimmunity to type II collagen: an experimental model of arthritis. J. Exp. Med. 146:857.
20. Ausar, S. F., Beltramo, D. M., Castagna, L. F., Quintana, S., Silvera, E., Kalayan, G., Revigliono, M., Landa, C. A. and Bianco, I. D. 2001. Treatment of rheumatoid arthritis by oral administration of bovine tracheal type II collagen. Rheumatol. Int. 20:138.
21. Laemmli, V. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 277:680.
22. 1 macrophages. FEBS Lett. 466:292.
23. Ausar, S. F., Landa, C. A., Bianco, I. D., Castagna, L. F. and Beltramo, D. M. 2001. Hydrolysis of a chitosan-induced milk aggregate by pepsin, trypsin and pancreatic lipase. Biosci. Biotechnol. Biochem. 65:2412.
24. Kruisbeek, A. M. 1997. In vitro assays for mouse lymphocyte function. In Coligan, J. E., Kruisbeek, A. M., Margulies, D. H., Shevach, E. M. and Strober, W., eds, Current Protocols in Immunology, p. 3.01. Wiley, New York.
25. Mozaffarian, N. Casadevall, A. and Berman, J. B. 2000. Inhibition of human opportunistic endothelial cell chemokine production by the opportunistic fungal pathogen Cryptococcus neoformans. J. Immunol. 165:1541.
26. Benson, J. M., Campbell, K. A., Guan, Z., Gienapp, I. E., Stuckman, S. S., Forsthuber, T. and Whitacre, C. C. 2000. T-cell activation and receptor down-modulation precede deletion induced by mucosally administered antigen. J. Clin. Invest. 106:1031.
27. Gütgemann, I., Fahrer, A. M., Altman, J. D., Davis, M. M. and Chien, Y. 1998. Induction of rapid T cell activation and tolerance by systemic presentation of an orally administered antigen. Immunity 8:667.
28. Pala, P., Hussell, T. and Openshaw, P. J. M. 2000. Flow cytometric measurement of intracellular cytokines. J. Immunol. Methods 243:107.
29. Zipris, D., Greiner, D. L., Malkani, S., Whalen, B., Mordes, J. P. and Rossini, A. A. 1996. Cytokine gene expression in islets and thyroids of BB rats. J. Immunol. 156:1315.
30. Brand, D. D., Myers, L. K., Whittington, K. B., Latham, K. A., Stuart, J. M., Kamg, A. H. and Rosloniec, E. F. 2002. Detection of early changes in autoimmune T cell phenotype and function following intravenous administration of type II collagen in a TCR-transgenic model. J. Immunol. 168:490.
31. Kim, W. U., Lee, W. K., Kim, S. H., Kim, J., Youn, J., Min, S. Y., Bae, E. Y., Hwang, S. Y., Park, S. H., Cho, C. S., Park, J. S. and Kim, H. Y. 2002. Suppression of collagen-induced arthritis by single administration of poly(lactic-co-glycolic acid) nanoparticles entrapping type II collagen. Arthritis Rheum. 46:1109
32. Nishimura, K., Ishihara, C., Ukei, S., Tokura, S. and Azuma, I. 1986. Stimulation of cytokine production in mice using deacetylated chitin. Vaccine 4:151.
33. Peluso, G., Petillo, O., Ranieri, M., Santin, M., Ambrosio, L., Calabro, D., Avallone, B. and Balsamo, G. 1994. Chitosan-mediated stimulation of macrophage function, Biomaterials 15:215.
34. Bernkop-Schnürch, A. and Kast, C. E. 2001. Chemically modified chitosans as enzyme inhibitors. Adv. Drug Deliv. Rev. 52:127.
35. Chen, Y., Inobe, J., Marks, R., Gonnella, P., Kuchroo, V. K. and Weiner, H. L. 1995. Peripheral deletion of antigen-reactive T cells in oral tolerance. Nature 376:177.
36. Elson, C. O. 1997. In defense of mucosal surfaces. Regulation and manipulation of the mucosal immune system. Adv. Exp. Med. Biol. 412:373.
37. Aplan O., Rudomen G. and Matzinger P. 2001. The role of dendritic cells, B cells, and M cells in gut-oriented immune responses. J. Immunol. 166:4843.
38. Fujihashi, K., Dohi, A., Rennert, P. D., Yamamoto, M., Koga, T., Kiyono, H. and McGhee, J. R. 2001. Peyer's patches are required for oral tolerance to proteins. Proc. Natl Acad. Sci. USA 98:3310.
39. Williamson, E., O'Malley, J. M. and Viney, J. L. 1999. Visualizing the T-cell responses elicited by oral administration of soluble protein antigens. Immunology 97:565.
40. Smith, K. M., Davidson, J. M. and Garside, P. 2002. T-cell activation occurs simultaneously in local and peripheral lymphoid tissue following oral administration of a range of doses of immunogenic or tolerogenic antigen although tolerized T cells display a defect in cell division. Immunology 106:144.
41. Sun, J., Dirden-Kramer, B., Ito, K., Ernst, P. B. and van Houten, N. 1999. Antigen-specific T cell activation and proliferation during oral tolerance induction. J. Immunol. 162:5868.
42. + T cells. J. Immunol. 159:591.
43. Hanson, D. G., Roy, M. J., Miller, S. D., Seidman, E. G., Thomas, M. J., Sanderson, I. R., Udall, J. N., Ely, I. and Green, G. M. 1993. Endopeptidase inhibition and intestinal antigen processing in mice. Reg. Immunol. 5:85.
44. Michaëlsson, E., Holmdahl, M., Engström, A., Burkhardt, H., Scheynius, A. and Holmdahl, R. 1995. Macrophages, but not dendritic cells, present collagen to T cells. Eur. J. Immunol. 25:2234.
45. Porporatto, C., Bianco, I. D., Riera, C. M. and Correa, S. G. 2003. Chitosan induces different L-arginine metabolic pathways in resting and inflammatory macrophages. Biochem. Biophys. Res. Commun. 304:266.
46. O'Garra, A. 1998. Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity 8:275.