Behavioral effects of intra-nigral microinjections of manganese chloride: Interaction with nitric oxide

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 24, Issue 2, 2000, Pages 307-325

  Ponzoni, Silvia ^a   Guimarães, Francisco S ^b   Del Bel, Elaine A ^b   Garcia Cairasco, Norberto ^b  

^a STATE UNIVERSITY OF LONDRINA   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Audiogenic seizures; Elevated plus maze; MnCl2; Nitric oxide; Parkinsonism rotational behavior; Substantia nigra

Indexed keywords

APOMORPHINE; MANGANESE CHLORIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANXIETY; ARTICLE; AUDIOGENIC SEIZURE; CIRCLING BEHAVIOR; MALE; MOTOR ACTIVITY; NERVE DEGENERATION; NONHUMAN; PARKINSONISM; RAT; SUBSTANTIA NIGRA; TRANQUILIZING ACTIVITY;

ANIMALS; ANXIETY DISORDERS; CHLORIDES; DRUG INTERACTIONS; MALE; MANGANESE COMPOUNDS; MOVEMENT DISORDERS; NITRIC OXIDE; RATS; SEIZURES; SUBSTANTIA NIGRA;

EID: 0034144017     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-5846(99)00090-1     Document Type: Article

References (61)

1. Altar, A., Neve, K.A., Loughlin, S.E., Marshall, J. F. and Fallion, J.H. (1983) The crossed mesostriatal projection: neurochemistry and developmental response to lesion. Brain Res. 279: 1-8.
2. Ariano, M.A., Lewicki, J.A., Brandwein, H. J. and Murad, F. (1982) Immunohistochemical localization of guanylate cyclase within neurons of rat brain. Proc. Natl. Acad. Sci. USA 79: 1316-1320.
3. Barbeau, A. (1984) Manganese and extrapyramidal disorders. Neurotoxicology 5:13-36.
4. Beal, M.F., Kowall, N.W., Ellison, D.W., Mazurek, M. F., Swartz K.J. and Martin, J.B. (1986) Repplication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature 321: 168-171.
5. Beal, M. F., Swartz, K.J., Hyman, B.T., Finn, S.F. and Koroshetz, W. (1991) Aminooxyacetic acid results in excitotoxin lesions by a novel direct mechanism. J. Neurochem. 57: 1068-1073.
6. Biagini, G, Ferraguti, F; Ponzoni, S; M. Zoli; L, Alboni; G. Tofano; K. Fuxe and L.F. Agnati. (1994) Neurochemical and behavioral studies on I-dopa toxicity in the model of manganese lesioned nigrostriatal pathway in the rat: evidence for a protective effect of the GM1 lactone siagoside. Wenner-Gren Symposium on Trophic regulation of the basal ganglia. Focus on dopamine neurons. K. Fuxe, L.F. Agnati, B. Bjelke, and D. Ohoson (Eds) , p 381-407.
7. Bredt, D.S. and Snyder, S.H. (1990) Isolation of nitric oxide synthetase, a calmodulin-requiring enzime. Proc. Natl. Acad. Sci. USA 87: 682-685.
8. Brouillet, E.P., L. Shinobu, U. McGarvey, Hochnerg, F. and Beal M. F. (1993) Manganese injection into the rat striatum produces excitotoxic lesions by imparing energy metabolism. Exp. Neurol. 120: 89-94.
9. Cabib S. and Puglisi-Allegra, S. (1996) Stress, depression and the mesolimbic dopamine system. Psychopharmacology 128: 331-342.
10. Calabresi, P., Pisani A., Centonze, D. and Bernardi, G. (1997) Synaptic plasticity and physiological interaction between dopamine and glutamate in the striatum. Neuroscience and Biobehavioral Rev. 21; 519-523.
11. Chandra, S.V. And Shukla, G.S. (1981) Concentration of striatal catecholamines in rats given manganese chloride through drinking water. J. Neurochem. 36: 683-687.
12. Choi, D.W. (1993) Nitric oxide: foe or friend to the injured brain. Proc Natl Acad Sci USA 90: 9741-9743.
13. Christie, J. E. and Crow, T.J. (1971) Turning behavior as an index of the action of amphetamine and ephedrines on central dopamine-containing neurones. Br. J. Pharmac. 43: 658-667.
14. Chu, N. S., Hochberg F.H., Calne, D.B. and Olanow C.W. (1995) Neurotoxicology of manganese. Handbook of neurotoxicology : 91-103.
15. 2 receptors blockade on fear-induced analgesia elicited by electrical stimulation of the deep layers of the superior colliculus and the dorsal periaqueductal gray. Behav. Brain Res., 87:97-103.
16. Coimbra, N.C., Kawasaki, M.C., Ciscato, J.G. Jr., Cardoso, S.H. and Corrêa, S.A. L. (1998). Nigro-tectal pathway: neuroanatomy and role on defensive behavior elicited by midbrain tectum stimulation. Society for Neuroscience Abstracts, 24:1930.
17. Costall, B., Marsden, C.D., Naylor, R.I. and Pycock, C.J., (1976) The relationship between striatal and mesolimbic dopamine dysfunction and the nature of circling responses following 6-OHDA and electrolytic lesions of the ascending dopamine systems of rats brain. Brain Res. 118: 87-113.
18. Cotzias, G.C. (1966) Manganese, melanin and the extrapyramidal system. J. Neurosurg. 24: 170-180.
19. Cotzias, G. C., Papavasiliou P. S., Girios J., Steck A. and Duby S. (1971) Metabolic modification on Parkinson's disease and the chronic manganese poisoning. Ann. Rev. Med. 22: 305-326.
20. Danielckzyk, W. (1992) Mental disorders in Parkinson's disease J. Neural. Transm [Suppl] 38: 115-127.
21. Dawson, V.L. and Dawson, T.M. (1996) Nitric Oxide actions in neurochemistry. Neurochem. 29:.97-110.
22. Dawson, T.M., Bredt, D.S., Fotuhi, M., Hwang, P.M. and Snyder, S.H. (1991) Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proc. Natl. Acad. Sci. USA 88: 7797-7801.
23. Del Bel, E.A., De Oliveira R.M.W. and Guimarães F.S.: (1998-a) Role of Nitric oxide on emotional and Motor Behavior a NATO Meeting/ASI series F volume : International School of Biophysics: Neural circuits and Networks; Prof. J Nicholls and Prof. V. Torre (editors)
24. Del Bel, E.A.; Oliveira, P.R., Oliveira, J.A.C.; Mishra, P.K.; Jobe, P.C. and Garcia-Cairasco, N (1997) Anticonvulsant and proconvulsant role of Nitric Oxide in experimental epilepsy models. Brazilian Journal of Medical and Biological Research 30 (8): 971-979.
25. Del Bel E.A, Da Silva C.A and Guimarães F.S (1998-b) Catalepsy induced by nitric Oxide synthase inhibitors. Gen. Pharmacol 30:245-248.
26. Doretto, M.C. and Garcia-Cairasco, N. (1995) Differential audiogenic seizure sensitization by selective unilateral substantia nigra lesions in resistant Wistar rats. Physiol. & Behav. 58: 273-282.
27. Eastwood, SL, Heffernan, J and Harrison, PJ (1997) Chronic haloperidol treatment differentially affects the expression of synaptic and neuronal plasticity associated genes. Mol. Psychiatry 2:322-329.
28. Fernandes, C., and File, S.E. (1996) The influence of open arm ledges and maze experiences in the elevated plus-maze. Pharmacol. Biochem. Behav. 54:31-40.
29. File, S.E. (1992) Behavioural detection of anxiolytic action. In: Experimental approaches to anxiety and depression, J.M. Eliot, D.J. Heal, and C.A. Marsden (Eds.), pp 25-44, John Wiley & Sons, New York.
30. File, S. E., Zangrossi, J. R., Vianna, H. and Graeff, F. G. (1993) Trial 2 in the elevated plus-maze: a different form of fear. Psychopharmacology 111: 491-494.
31. Garant, D. and Gale, K. (1987) Substantia nigra-mediated anticonvulsant actions: role of nigral output pathways, Exp. Neural. 97: 143-159.
32. Garcia-Cairasco, N., Wakamatsu, H., Oliveira, J.A.C., Oliveira, J.A.C., Gomes, E.L.T., Del Bel, E.A. and Mello, L. E. A. M. (1996) Neuroethological and morphological (Neo-Timm stainning) correlates of limbic recruitment during the development of audiogenic kindling in seizure susceptible Wistar rats. Epilepsy Research, 26:177-192.
33. Garcia-Cairasco, N. and Sabbatini, R.M.E. (1991) Possible interaction between the inferior colliculus and the substantia nigra in audiogenic seizures in rats. Physiol. & Behavior 50: 421-427.
34. Garcia-Cairasco, N. and Triviño-Santos, H.F. (1989) Effects of both 60HDA-induced and electrolytic lesions in the substantia nigra on the rotational behavior and audiogenic seizures in the rat. Braz. J. Med. Biol. Res. 22: 617-629.
35. Garcia-Cairasco, N., Oliveira, J.A.C., Wakamatsu, H., Bueno, S.T.B. and Guimarães, F.S. (1998) Reduced exploratory activity of audiogenic seizures susceptible Wistar rats. Physiol. Behav, 64(5):671-674,.
36. Gerfen, C. R, Staines, W.A., Arbuthnott, G.W. and Fibiger, H.C. (1982) Crossed connections of the substantia nigra in the rat J. Com. Neurol. 207: 283-303.
37. Gorel, J. M., Johnson, C. C., Rybicki, A., B., Peterson, E.L., Korstha, G. X., Brown, G.G. and Richardson, R.J. (1997) Occupational exposures to metals as risk factors for Parkinson's disease. Neurology 48: 650-658.
38. Graeff F.G, Guimarães F.S, Andrade T.G.C.S and Deakin J.F.W. (1996). Role of 5-HT in stress, anxiety and depression. Pharmacol Biochem Behav 54: 129-14.
39. Graham, D.G. (1978) Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones. Mol. Pharmacol. 14: 633-643.
40. Guimarães F.S., De Aguiar J.C., Del Bel E.A. and Ballejo G. (1994) Anxiolytic effect of nitric oxide inhibitors microinjected into the dorsal central grey. NeuroReport 5, 1929-1932.
41. Hökfelt T., Ceccatelli S, Gustafsson L, Hulting A-L, Verge V, Villar M, Xiao-Jun XU, Zhi-Qing XU, Wiesenfeld-Hallin Z, and Xu-Zhang (1994) Plasticity of NO synthase expression in the nervous and endocrine systems. Neuropharmacology 33: 221-1227
42. Inoue, N., Tsukada, Y. and Barbeau, A. (1975) Behavioral effects in rats following intrastriatal microinjection of manganese. Brain Res. 95: 103-124.
43. Iwamoto, E.T., Loh, H.H. and Way, E.L. (1976) Circling behavior in rats with 6-OHDA or electrolytic nigral lesion. Eur. J. Pharmacol. 37: 339-356.
44. Klivenyi P., St. Clair, D., Wermer, M., Yen, H-Ch., Oberlay, T., Yang, L. and Beal, M. F. (1998). Manganese superoxide dismutase overexpression attenuates MPTP toxicity. Neurobiol. Disease. 5: 253-258.
45. Lino De Oliveira, C., Del Bel, E.A. and Guimarães, F.S. (1997) Effects of L-NOARG on plus-maze performance in rats. Pharmacol. Biochem. Behav. 56: 55-59.
46. Marras R, Martins A.P, Del Bel E.A and Guimarães F.S (1995) L-NOARG, an inhibitor of nitric oxide synthase, induces catalepsy in mice. NeuroReport 7: 158-160.
47. Mufson, EJ and Brandabur, MM (1994) Sparing of NADPH-diaphorase striatal neurons in Parkinson's and Alzheimer's diseases. NeuroReport 5: 705-708.
48. Parenti, M., Flauto, C., Parati, E., Vescovi, A. and Groppetti, A. (1986) Manganese neurotoxicity: effects of I-dopa and pargiline treatments. Brain Res. 367: 8-13.
49. Paxinos, G and Watson, C. (1986) The rat brain in stereotaxic coordinates Academic Press.
50. Ponzoni, S., Guimarães, F.S and Garcia-Cairasco, N. (1995) Experimental model of Parkinson disease: intranigric microinjections of manganese chloride and its effects on audiogenic seizures susceptibility and the elevated plus maze. Psiquiatria Clinica 22: 135-136.
51. Pruzuntek, H. (1992) Early diagnosis in Parkinson's disease. J. Neural. Transm.[Suppl] 38: 105-114.
52. Pycock, C.J. (1980) Turning behaviour in animals. Neuroscience 5: 461-514.
53. Regidor J, Montesdeoca J, Ramirez-Gonzalez J A, Hernandez-Urquia C M, and Divac I (1993) Bilateral induction of NADPH-diaphorase activity in neocortical and hippocampal neurons by unilateral injury. Brain Res 631:171-174
54. Robertson, G.S and Robertson, H.A. (1989) Evidence that L-dopa-induced rotational behavior is dependent on both striatal and nigral mechanisms. J. Neurosci. 9: 3326-3331.
55. Samberg P.R, Bunsey M.D, Giordano M and Norman A.B (1988) The catalepsy test: its ups and downs. Behav Neurosci 102:748-759.
56. Schuman, E.M and Madison, D.V. (1994) Nitric oxide and synaptic function.Annu.Ver.Neursoci. 17: 153-183.
57. Treit, D., Menard, J., and Royan, C. (1993) Anxiogenic stimuli in the elevated plus-maze. Pharmacol. Biochem. Behav. 44: 463-469.
58. Ungerstedt, U. (1971) Postsynaptic supersensitivity after 6-OHDA induced degeneration of the nigrostriatal dopamine system. Acta Physiol. Scand. Suppl. 367: 69-93.
59. Ungerstedt, U. and Arbuthnott, G. (1970) Quantitative recording of rotational behaviour in rats after 6-OHDA lesions of the nigro striatal dopamine system. Brain Res. 24: 485-493.
60. Vincent, S. R. and Johansson, O. (1983) Striatal neurons containing both somatostatinand avian pancreatic polypeptide (APP)-like immunoreactivities and NADPH-diaphorase activity: a light and electron microscopic study. J. Comp. Neural. 217: 264-270.
61. Vincent, S. R. and Kimura, H. (1992) Histochemical mapping of nitric oxide synthase in the rat brain. Neuroscience 46: 755-784.