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Volumn 19, Issue 10, 2005, Pages 1007-1014

Pertussis toxin B-oligomer dissociates T cell activation and HIV replication in CD4 T cells released from infected lymphoid tissue

Author keywords

HIV; Latency; Lymphoid tissue; PTX; T cell proliferation

Indexed keywords

CD4 ANTIGEN; DNA; INTERLEUKIN 2; OLIGOMER; PERTUSSIS TOXIN; PHYTOHEMAGGLUTININ; THYMIDINE; VIRUS DNA;

EID: 21844454243     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.aids.0000174446.40379.3b     Document Type: Article
Times cited : (22)

References (34)
  • 1
    • 18144435424 scopus 로고    scopus 로고
    • Evolutionary pattern of human immunodeficiency virus (HIV) replication and distribution in lymph nodes following primary infection: Implications for antiviral therapy
    • Pantaleo C, Cohen OJ, Schacker T, Vaccarezza M, Graziosi C, Rizzardi GP, et al. Evolutionary pattern of human immunodeficiency virus (HIV) replication and distribution in lymph nodes following primary infection: implications for antiviral therapy. Nat Med 1998; 4:341-345.
    • (1998) Nat Med , vol.4 , pp. 341-345
    • Pantaleo, C.1    Cohen, O.J.2    Schacker, T.3    Vaccarezza, M.4    Graziosi, C.5    Rizzardi, G.P.6
  • 2
    • 0027538456 scopus 로고
    • HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease
    • Pantaleo G, Graziosi C, Demarest JF, Butini L, Montroni M, Fox CH, et al. HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature 1993; 362:355-358.
    • (1993) Nature , vol.362 , pp. 355-358
    • Pantaleo, G.1    Graziosi, C.2    Demarest, J.F.3    Butini, L.4    Montroni, M.5    Ch, F.6
  • 3
    • 0027516822 scopus 로고
    • Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS
    • Embretson J, Zupancic M, Ribas JL, Burke A, Racz P, Tenner-Racz K, et al. Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS. Nature 1993; 362:359-362.
    • (1993) Nature , vol.362 , pp. 359-362
    • Embretson, J.1    Zupancic, M.2    Ribas, J.L.3    Burke, A.4    Racz, P.5    Tenner-Racz, K.6
  • 4
    • 0030933113 scopus 로고    scopus 로고
    • Experimental HIV infection of human lymphoid tissue: Correlation of CD4+ T cell depletion and virus syncytium-inducing/non-syncytium-inducing phenotype in histocultures inoculated with laboratory strains and patient isolates of HIV type 1
    • Glushakova S, Baibakov B, Zimmerberg J, Margolis LB. Experimental HIV infection of human lymphoid tissue: correlation of CD4+ T cell depletion and virus syncytium-inducing/non-syncytium-inducing phenotype in histocultures inoculated with laboratory strains and patient isolates of HIV type 1. AIDS Res Hum Retroviruses 1997; 13:461-471.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 461-471
    • Glushakova, S.1    Baibakov, B.2    Zimmerberg, J.3    Margolis, L.B.4
  • 6
    • 0033011115 scopus 로고    scopus 로고
    • CCR5- and CXCR4-tropic HIV-1 are equally cytopathic for their T-cell targets in human lymphoid tissue
    • Grivel JC, Margolis LB. CCR5- and CXCR4-tropic HIV-1 are equally cytopathic for their T-cell targets in human lymphoid tissue. Nat Med 1999; 5:344-346.
    • (1999) Nat Med , vol.5 , pp. 344-346
    • Grivel, J.C.1    Margolis, L.B.2
  • 7
    • 0033871199 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 induces apoptosis in CD4(+) but not in CD8(+) T cells in ex vivo-infected human lymphoid tissue
    • Grivel JC, Malkevitch N, Margolis L. Human immunodeficiency virus type 1 induces apoptosis in CD4(+) but not in CD8(+) T cells in ex vivo-infected human lymphoid tissue. J Virol 2000; 74:8077-8084.
    • (2000) J Virol , vol.74 , pp. 8077-8084
    • Grivel, J.C.1    Malkevitch, N.2    Margolis, L.3
  • 9
    • 0020362248 scopus 로고
    • Subunit structure of islet-activating protein, pertussis toxin, in conformity with the A-B model
    • Tamura M, Nogimori K, Murai S, Yajima M, Ito K, Katada T, et al. Subunit structure of islet-activating protein, pertussis toxin, in conformity with the A-B model. Biochemistry 1982; 21:5516-5522.
    • (1982) Biochemistry , vol.21 , pp. 5516-5522
    • Tamura, M.1    Nogimori, K.2    Murai, S.3    Yajima, M.4    Ito, K.5    Katada, T.6
  • 10
    • 0029970109 scopus 로고    scopus 로고
    • Mechanisms of pertussis toxin-induced myelomonocytic cell adhesion: Role of Mac-1 (CD11b/CD18) and urokinase receptor (CD87)
    • Wong WS, Simon DI, Rosoff PM, Rao NK, Chapman HA. Mechanisms of pertussis toxin-induced myelomonocytic cell adhesion: role of Mac-1 (CD11b/CD18) and urokinase receptor (CD87). Immunology 1996; 88:90-97.
    • (1996) Immunology , vol.88 , pp. 90-97
    • Wong, W.S.1    Simon, D.I.2    Rosoff, P.M.3    Rao, N.K.4    Chapman, H.A.5
  • 11
    • 0033854453 scopus 로고    scopus 로고
    • Mechanisms of pertussis toxin-induced myelomonocytic cell adhesion: Role of CD14 and urokinase receptor
    • Li H, Wong WS. Mechanisms of pertussis toxin-induced myelomonocytic cell adhesion: role of CD14 and urokinase receptor. Immunology 2000; 100:502-509.
    • (2000) Immunology , vol.100 , pp. 502-509
    • Li, H.1    Wong, W.S.2
  • 12
    • 0029824649 scopus 로고    scopus 로고
    • Pharmacology of pertussis toxin B-oligomer
    • Wong WS, Rosoff PM. Pharmacology of pertussis toxin B-oligomer. Can J Physiol Pharmacol 1996; 74:559-564.
    • (1996) Can J Physiol Pharmacol , vol.74 , pp. 559-564
    • Wong, W.S.1    Rosoff, P.M.2
  • 13
    • 0031920860 scopus 로고    scopus 로고
    • Pertussis toxin potentiates Th1 and Th2 responses to co-injected antigen: Adjuvant action is associated with enhanced regulatory cytokine production and expression of the co-stimulatory molecules B7-1, B7-2 and CD28
    • Ryan M, McCarthy L, Rappuoli R, Mahon BP, Mills KH. Pertussis toxin potentiates Th1 and Th2 responses to co-injected antigen: adjuvant action is associated with enhanced regulatory cytokine production and expression of the co-stimulatory molecules B7-1, B7-2 and CD28. Int Immunol 1998; 10:651-662.
    • (1998) Int Immunol , vol.10 , pp. 651-662
    • Ryan, M.1    McCarthy, L.2    Rappuoli, R.3    Mahon, B.P.4    Mills, K.H.5
  • 15
    • 0030959440 scopus 로고    scopus 로고
    • Rational design of vaccines
    • Rappuoli R. Rational design of vaccines. Nat Med 1997; 3:374-376.
    • (1997) Nat Med , vol.3 , pp. 374-376
    • Rappuoli, R.1
  • 16
    • 0030866249 scopus 로고    scopus 로고
    • Acellular pertussis vaccines containing genetically detoxified pertussis toxin induce long-lasting humoral and cellular responses in adults
    • Di Tommaso A, Bartalini M, Peppoloni S, Podda A, Rappuoli R, De Magistris MT. Acellular pertussis vaccines containing genetically detoxified pertussis toxin induce long-lasting humoral and cellular responses in adults. Vaccine 1997; 15:1218-1224.
    • (1997) Vaccine , vol.15 , pp. 1218-1224
    • Di Tommaso, A.1    Bartalini, M.2    Peppoloni, S.3    Podda, A.4    Rappuoli, R.5    De Magistris, M.T.6
  • 17
    • 0035253575 scopus 로고    scopus 로고
    • The binding subunit of pertussis toxin inhibits HIV replication in human macrophages and virus expression in chronically infected promonocytic U1 cells
    • Alfano M, Vallanti G, Biswas P, Bovolenta C, Vicenzi E, Mantelli B, et al. The binding subunit of pertussis toxin inhibits HIV replication in human macrophages and virus expression in chronically infected promonocytic U1 cells. J Immunol 2001; 166:1863-1870.
    • (2001) J Immunol , vol.166 , pp. 1863-1870
    • Alfano, M.1    Vallanti, G.2    Biswas, P.3    Bovolenta, C.4    Vicenzi, E.5    Mantelli, B.6
  • 18
    • 0032821914 scopus 로고    scopus 로고
    • The B-oligomer of pertussis toxin deactivates CC chemokine receptor 5 and blocks entry of M-tropic HIV-1 strains
    • Alfano M, Schmidtmayerova H, Amelia CA, Pushkarsky T, Bukrinsky M. The B-oligomer of pertussis toxin deactivates CC chemokine receptor 5 and blocks entry of M-tropic HIV-1 strains. J Exp Med 1999; 190:597-605.
    • (1999) J Exp Med , vol.190 , pp. 597-605
    • Alfano, M.1    Schmidtmayerova, H.2    Amelia, C.A.3    Pushkarsky, T.4    Bukrinsky, M.5
  • 19
    • 0027930165 scopus 로고
    • Pertussis toxin inhibits induction of human immunodeficiency virus type 1 in infected monocytes
    • Chowdhury IH, Koyanagi Y, Hazeki O, Ui M, Yamamoto N. Pertussis toxin inhibits induction of human immunodeficiency virus type 1 in infected monocytes. Virology 1994; 203:378-383.
    • (1994) Virology , vol.203 , pp. 378-383
    • Chowdhury, I.H.1    Koyanagi, Y.2    Hazeki, O.3    Ui, M.4    Yamamoto, N.5
  • 20
    • 0032865672 scopus 로고    scopus 로고
    • Envelope-dependent restriction of human immunodeficiency virus type 1 spreading in CD4(+) T lymphocytes: R5 but not X4 viruses replicate in the absence of T-cell receptor restimulation
    • Vicenzi E, Bordignon PP, Biswas P, Brambilla A, Bovolenta C, Cota M, et al. Envelope-dependent restriction of human immunodeficiency virus type 1 spreading in CD4(+) T lymphocytes: R5 but not X4 viruses replicate in the absence of T-cell receptor restimulation. J Virol 1999; 73:7515-7523.
    • (1999) J Virol , vol.73 , pp. 7515-7523
    • Vicenzi, E.1    Bordignon, P.P.2    Biswas, P.3    Brambilla, A.4    Bovolenta, C.5    Cota, M.6
  • 21
    • 0036852881 scopus 로고    scopus 로고
    • Restricted replication of primary HIV-1 isolates using both CCR5 and CXCR4 in Th2 but not in Th1 CD4(+) T cells
    • Vicenzi E, Panina-Bodignon P, Vallanti G, Di Lucia P, Poli G. Restricted replication of primary HIV-1 isolates using both CCR5 and CXCR4 in Th2 but not in Th1 CD4(+) T cells. J Leukoc Biol 2002; 72:913-920.
    • (2002) J Leukoc Biol , vol.72 , pp. 913-920
    • Vicenzi, E.1    Panina-Bodignon, P.2    Vallanti, G.3    Di Lucia, P.4    Poli, G.5
  • 23
    • 0031927822 scopus 로고    scopus 로고
    • Binding of human immunodeficiency virus type 1 to CD4 and CXCR4 receptors differentially regulates expression of inflammatory genes and activates the MEK/ERK signaling pathway
    • Popik W, Hesselgesser JE, Pitha PM. Binding of human immunodeficiency virus type 1 to CD4 and CXCR4 receptors differentially regulates expression of inflammatory genes and activates the MEK/ERK signaling pathway. J Virol 1998; 72:6406-6413.
    • (1998) J Virol , vol.72 , pp. 6406-6413
    • Popik, W.1    Hesselgesser, J.E.2    Pitha, P.M.3
  • 24
    • 0032488235 scopus 로고    scopus 로고
    • Early activation of mitogen-activated protein kinase kinase, extracellular signal-regulated kinase, p38 mitogen-activated protein kinase, and c-Jun N-terminal kinase in response to binding of simian immunodeficiency virus to Jurkat T cells expressing CCR5 receptor
    • Popik W, Pitha PM. Early activation of mitogen-activated protein kinase kinase, extracellular signal-regulated kinase, p38 mitogen-activated protein kinase, and c-Jun N-terminal kinase in response to binding of simian immunodeficiency virus to Jurkat T cells expressing CCR5 receptor. Virology 1998; 252:210-217.
    • (1998) Virology , vol.252 , pp. 210-217
    • Popik, W.1    Pitha, P.M.2
  • 25
    • 0034005659 scopus 로고    scopus 로고
    • Inhibition of CD3/CD28-mediated activation of the MEK/ERK signaling pathway represses replication of X4 but not R5 human immunodeficiency virus type 1 in peripheral blood CD4(+) T lymphocytes
    • Popik W, Pitha PM. Inhibition of CD3/CD28-mediated activation of the MEK/ERK signaling pathway represses replication of X4 but not R5 human immunodeficiency virus type 1 in peripheral blood CD4(+) T lymphocytes. J Virol 2000; 74:2558-2566.
    • (2000) J Virol , vol.74 , pp. 2558-2566
    • Popik, W.1    Pitha, P.M.2
  • 26
    • 0031020906 scopus 로고    scopus 로고
    • The lymphocytosis-promoting agent pertussis toxin affects virus burden and lymphocyte distribution in the SIV-infected rhesus macaque
    • Pauza CD, Hinds PW 2nd, Yin C, McKechnie TS, Hinds SB, Salvato MS. The lymphocytosis-promoting agent pertussis toxin affects virus burden and lymphocyte distribution in the SIV-infected rhesus macaque. AIDS Res Hum Retroviruses 1997; 13:87-95.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 87-95
    • Pauza, C.D.1    Hinds II, P.W.2    Yin, C.3    McKechnie, T.S.4    Hinds, S.B.5    Salvato, M.S.6
  • 27
    • 17644369236 scopus 로고    scopus 로고
    • Pertussis toxin B-oligomer inhibits HIV infection and replication in hu-PBL-SCID mice
    • Lapenta C, Spada M, Santini SM, Racca S, Dorigatti F, Poli G, et al. Pertussis toxin B-oligomer inhibits HIV infection and replication in hu-PBL-SCID mice. Int Immunol 2005; 17:469-475.
    • (2005) Int Immunol , vol.17 , pp. 469-475
    • Lapenta, C.1    Spada, M.2    Santini, S.M.3    Racca, S.4    Dorigatti, F.5    Poli, G.6
  • 28
    • 0036434233 scopus 로고    scopus 로고
    • B-oligomer of pertussis toxin inhibits HIV-1 LTR-driven transcription through suppression of NF-kappaB p65 subunit activity
    • Iordanskiy S, Iordanskaya T, Quivy V, Van Lint C, Bukrinsky M. B-oligomer of pertussis toxin inhibits HIV-1 LTR-driven transcription through suppression of NF-kappaB p65 subunit activity. Virology 2002; 302:195-206.
    • (2002) Virology , vol.302 , pp. 195-206
    • Iordanskiy, S.1    Iordanskaya, T.2    Quivy, V.3    Van Lint, C.4    Bukrinsky, M.5
  • 29
    • 4143061435 scopus 로고    scopus 로고
    • Analysis of human immunodeficiency virus type 1 transcriptional elongation in resting CD4+ T cells in vivo
    • Lassen KC, Bailey JR, Siliciano RF. Analysis of human immunodeficiency virus type 1 transcriptional elongation in resting CD4+ T cells in vivo. J Virol 2004; 78:9105-9114.
    • (2004) J Virol , vol.78 , pp. 9105-9114
    • Lassen, K.C.1    Bailey, J.R.2    Siliciano, R.F.3
  • 30
    • 0031010762 scopus 로고    scopus 로고
    • Differential susceptibility of naive and memory CD4+ T cells to the cytopathic effects of infection with human immunodeficiency virus type 1 strain LAI
    • Chun TW, Chadwick K, Margolick J, Siliciano RF. Differential susceptibility of naive and memory CD4+ T cells to the cytopathic effects of infection with human immunodeficiency virus type 1 strain LAI. J Virol 1997; 71:4436-4444.
    • (1997) J Virol , vol.71 , pp. 4436-4444
    • Chun, T.W.1    Chadwick, K.2    Margolick, J.3    Siliciano, R.F.4
  • 31
    • 0034126953 scopus 로고    scopus 로고
    • In vitro reactivation of human immunodeficiency virus 1 from latently infected, resting CD4+ T cells after bacterial stimulation
    • Moriuchi H, Moriuchi M, Mizell SB, Ehler LA, Fauci AS. In vitro reactivation of human immunodeficiency virus 1 from latently infected, resting CD4+ T cells after bacterial stimulation. J Infect Dis 2000; 181:2041-2044.
    • (2000) J Infect Dis , vol.181 , pp. 2041-2044
    • Moriuchi, H.1    Moriuchi, M.2    Mizell, S.B.3    Ehler, L.A.4    Fauci, A.S.5
  • 32
    • 0032490570 scopus 로고    scopus 로고
    • Induction of HIV-1 replication in latently infected CD4+ T cells using a combination of cytokines
    • Chun TW, Engel D, Mizell SB, Ehler LA, Fauci AS. Induction of HIV-1 replication in latently infected CD4+ T cells using a combination of cytokines. J Exp Med 1998; 188:83-91.
    • (1998) J Exp Med , vol.188 , pp. 83-91
    • Chun, T.W.1    Engel, D.2    Mizell, S.B.3    Ehler, L.A.4    Fauci, A.S.5
  • 33
    • 0032953920 scopus 로고    scopus 로고
    • Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
    • Finzi D, Blankson J, Siliciano JD, Margolick JB, Chadwick K, Pierson T, et al. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nat Med 1999; 5:512-517.
    • (1999) Nat Med , vol.5 , pp. 512-517
    • Finzi, D.1    Blankson, J.2    Siliciano, J.D.3    Margolick, J.B.4    Chadwick, K.5    Pierson, T.6
  • 34
    • 0033797161 scopus 로고    scopus 로고
    • Genetic characterization of rebounding HIV-1 after cessation of highly active antiretroviral therapy
    • Zhang L, Chung C, Hu BS, He T, Guo Y, Kim AJ, et al. Genetic characterization of rebounding HIV-1 after cessation of highly active antiretroviral therapy. J Clin Invest 2000; 106:839-845.
    • (2000) J Clin Invest , vol.106 , pp. 839-845
    • Zhang, L.1    Chung, C.2    Hu, B.S.3    He, T.4    Guo, Y.5    Kim, A.J.6


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