Proteasome complex as a potential cellular target of hepatitis B virus X protein

Journal of Virology

Volumn 70, Issue 8, 1996, Pages 5582-5591

  Huang, Jiakang ^a   Kwong, Joel ^a   Sun, Edward C Y ^a   Liang, T Jake ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEASOME; VIRUS PROTEIN;

ARTICLE; BINDING AFFINITY; HEPATITIS B VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE;

EID: 0029986179     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.8.5582-5591.1996     Document Type: Article

References (58)

1. Andersson, M., S. Paabo, T. Nilsson, and P. A. Peterson. 1985. Impaired intracellular transport of class 1 MHC antigens as a possible means for adenoviruses to evade immune surveillance. Cell 43:215-222.
2. Arii, M., S. Takada, and K. Koike. 1992. Identification of three essential regions of hepatitis B virus X protein for transactivation function. Oncogene 7:397-403.
3. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1991. Current protocols in molecular biology. John Wiley & Sons, New York.
4. Benn, J., and R. J. Schneider. 1994. HBV HBx protein establishes a Ras, Raf, MAP kinase signalling cascade and stimulates cell proliferation through activation of p34cdc2 kinase-cyclin B complexes. Proc. Natl. Acad. Sci. USA 91:10350-10354.
5. Brown, M. G., J. Driscoll, and J. J. Monaco. 1991. Structural and serological similarity of MHC-linked LMP and proteasome (multicatalytic proteinase) complexes. Nature (London) 353:355-357.
6. Burgert, H.-G., and S. Kvist. 1985. An adenovirus type 2 glycoprotein blocks cell surface expression of human histocompatibility class I antigens. Cell 41:987-997.
7. Chen, H.-S., S. Kaneko, R. Girones, R. W. Anderson, W. E. Hornbuckle, B. C. Tennant, P. J. Cote, J. L. Gerin, R. H. Purcell, and R. H. Miller. 1993. The woodchuck hepatitis X gene is important for establishment of virus infection in woodchucks. J. Virol. 67:1218-1226.
8. Cheong, J., M. Yi, Y. Lin, and S. Murakami. 1995. Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation. EMBO J. 14:143-150.
9. Colgrove, R., G. Simon, and D. Ganem. 1989. Transcriptional activation of homologous and heterologous genes by the hepatitis B virus X gene product in cells permissive for viral replication. J. Virol. 63:4019-4026.
10. Creighton, T. E. 1984. Proteins, structures and molecular principles. Freeman, New York.
11. Cross, J. C., P. Wen, and W. Rutter. 1993. Transactivation by hepatitis B virus X protein is promiscuous and dependent on mitogen-activated cellular serine/threonine kinases. Proc. Natl. Acad. Sci. USA 90:8078-8082.
12. Doria, M., N. Klein, R. Lucito, and R. J. Schneider. 1995. The hepatitis B virus HBX protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors. EMBO J. 14:4747-4757.
13. Fields, S., and O.-K. Song. 1989. A novel genetic system to detect protein-protein interactions. Nature (London) 340:245-246.
14. Gaczynska, M., K. Rock, and A. Goldberg. 1993. γ-Interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes. Nature (London) 365:264-266.
15. Gaczynska, M., K. L. Rock, T. Spies, and A. L. Goldberg. 1994. Peptidase activities of proteasomes are differently regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7. Proc. Natl. Aead. Sci. USA 91:9213-9217.
16. Genschik, P., G. Philipps, C. Gigot, and J. Fleck. 1992. Cloning and sequence analysis of a cDNA clone from Arabidopsis thaliana homologous to a proteasome a subunit from Drosophila. FEBS Lett. 309:311-315.
17. Glotzer, M., A. W. Murray, and M. W. Kirschner. 1991. Cyclin is degraded by the ubiquitin pathway. Nature (London) 349:132-138.
18. Glynne, R., S. H. Powis, S. Beck, A. Kelly, L.-A. Kerr, and J. Trowsdale. 1991. A proteasome-related gene between the two ABC transporter loci in the class II region of the human MHC. Nature (London) 353:357-360.
19. Goldberg, A. L. 1995. Functions of the proteasome: the lysis at the end of the tunnel. Science 268:522-523.
20. Goldberg, A. L., and K. L. Rock. 1992. Proteolysis, proteasomes and antigen presentation. Nature (London) 357:375-379.
21. Guilhot, S., P. Fowler, G. Portillo, R. Margolskee, A. Ferrari, A. Bertoletti, and F. Chisari. 1992. Hepatitis B virus-specific cytotoxic T-cell response in humans: production of target cells by stable expression of HBV-encoded proteins in immortalized human B-cell lines. J. Virol. 66:2670-2678.
22. Gyuris, J., E. Golemis, H. Chertkov, and R. Brent. 1993. Cdil, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell 75:791-803.
23. Haass, C., B. Pesold-Hurt, G. Multhaup, K. Beyreuther, and P.-M. Kloetzel. 1990. The Drosophila PROS-28.1 gene is a member of the proteasome gene family. Gene 90:235-241.
24. Hendil, K. B., and W. Uerkvitz. 1991. The human multicatalytic proteinase: affinity purification using a monoclonal antibody. J. Biochem. Biophys. Methods 22:159-165.
25. Hershko, A., and A. Ciechanover. 1992. The ubiquitin system for protein degradation. Annu. Rev. Biochem. 61:761-807.
26. Hochstrasser, M., and A. Varshavsky. 1990. In vivo degradation of transcriptional regulator: the yeast α2 repressor. Cell 61:697-708.
27. Jentsch, S., and S. Schienker. 1995. Selective protein degradation: a journey's end within the proteasome. Cell 82:881-884.
28. Kekule, A. S., U. Lauer, L. Weiss, B. Luber, and P. H. Hofschneider. 1993. Hepatitis B virus transactivator HBX uses a tumor promoter signalling pathway. Nature (London) 361:742-745.
29. Kim, C. M., K. Koike, I. Saito, T. Miyamura, and G. Jay. 1991. HBX gene of hepatitis B virus induces liver cancer in transgenic mice. Nature (London) 315:317-320.
30. Kumalori, A., K. Tanaka, N. Inamura, S. Sone, T. Ogura, T. Matsumoto, T. Tachikawa, S. Shin, and A. Ichihara. 1990. Abnormally high expression of proteasomes in human leukemic cells. Proc. Natl. Acad. Sci. USA 87:7071-7075.
31. Lee, T. H., S. J. Elledge, and J. S. Butel. 1995. Hepatitis B virus X protein interacts with a probable cellular DNA repair protein. J. Virol. 69:1107-1114.
32. Levero, M., M. Stemler, C. Pasquinelli, A. Alberti, O. Jean-Jean, A. Franco, C. Balsano, D. Diop, C. Brechot, M. Melegari, E. Villa, V. Barnaba, M. Perricaudet, and H. Will. 1991. Significance of anti-HBs antibodies in hepatitis B virus infection. Hepatology 13:131-149.
33. Liu, Z. L., D. B. Batt, and G. G. Carmichael. 1994. Targeted nuclear antisense RNA mimics natural antisensc-induced degradation of polyoma virus early RNA. Proc. Natl. Acad. Sci. USA 91:4258-4262.
34. Lowe, J., D. Stock, B. Jap, P. Zwicki, W. Baumeister, and R. Huber. 1995. Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution. Science 268:533-539.
35. Maguire, H. F., J. P. Hoeffler, and A. Siddiqui. 1991. HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions. Science 252:842-844.
36. Neefjes, J. J., and F. Momburg. 1993. Cell biology of antigen presentation. Curr. Opin. Immunol. 5:27-34.
37. Nordeen, S. K. 1988. Luciferase reporter gene vectors for analysis of promoters and enhancers. BioTechniques 6:454-457.
38. Oldstone, M. B. 1991. Molecular anatomy of viral persistence. J. Virol. 65:6381-6386.
39. Palombella, V. J., O. Rando, A. L. Goldberg, and T. Maniatis. 1994. Processing of the NF-kB1 (p105) precursor protein and the degradation of IkB-a require the proteasome. Cell 78:773-785.
40. Papavassiliou, A. G., M. Treier, C. Chavrier, and D. Bohmann. 1992. Targeted degradation of c-fos, but not v-fos, by a phosphorylation-dependent signal on c-JUN. Science 258:1941-1944.
41. Puhler, G., S. Weinkauf, L. Bachmann, S. Muller, A. Engel, R. Hegeri, and W. Baumeister. 1992. Subunit stoichiometry and three dimensional arrangement in proteasome from thermoplasma acidophilum. EMBO J. 11:1607-1616.
42. Qadri, I., H. F. Maguire, and A. Siddiqui. 1995. Hepatitis B virus transactivator protein X interacts with TATA-binding protein. Proc. Natl. Acad. Sci. USA 92:1003-1007.
43. Rechsteiner, M., L. Hoffman, and W. Dubiel. 1993. The multicalalytic and 26S protease. J. Biol. Chem. 268:6065-6068.
44. Rock, K. L., C. Gramm, L. Rothstein, K. Clark, R. Stein, L. Dick, D. Hwang, and A. L. Goldberg. 1994. Inhibitors of the proteasome block the degradation of most cell protein and generation of peptides presented on MHC class I molecules. Cell 78:761-771.
45. Runkel, L., M. Fischer, and H. Shaller. 1993. Two-codon insertion mutations of the HBX define two separate regions necessary for its trans-activation function. Virology 197:529-536.
46. Seto, E., P. J. Mitchell, and T. S. B. Yen. 1990. Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors. Nature (London) 344:72-74.
47. Siddiqui, A., S. Jameel, and J. Mapoles. 1987. Expression of the hepatitis B virus X gene in mammalian cells. Proc. Natl. Acad. Sci. USA 84:2513-2517.
48. Takada, S., and K. Koike. 1990. X protein of hepatitis B virus resembles a serine protease inhibitor. Jpn. J. Cancer Res. 81:1191-1194.
49. Tamura, T., D. H. Lee, F. Osaka, T. Fujiwara, S. Shin, C. H. Chung, K. Tanaka, and A. Ichihara. 1991. Molecular cloning and sequence analysis of cDNAs for five major subunits of human proteasomes (multi-catalytic proteinase complex). Biochim. Biophys. Acta 1089:95-102.
50. Tanaka, K. Personal communication.
51. Tanaka, K., T. Tamura, T. Yoshimura, and A. Ichihara. 1992. Proteasomes: protein and gene structures. New Biol. 4:173-187.
52. Truant, R., J. Antunovic, J. Greenblatt, C. Prives, and J. A. Gromlish. 1995. Direct interaction of the hepatitis B virus HBX protein with p53 lends to inhibition by HBX of p53 response element-directed transactivation. J. Virol. 69:1851-1859.
53. Unger, T., and Y. Shaul. 1990. The X protein of the hepatitis B virus acts as a transcription factor when targeted to its responsive element. EMBO J. 9:1889-1895.
54. Wang, X. W., K. Forrester, H. Yeh, M. A. Feitelson, J.-R. Gu, and C. C. Harris. 1994. Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3. Proc. Natl. Acad. Sci. USA 91:2230-2234.
55. Weissman, J. S., P. B. Sigler, and A. L. Horwich. 1995. From the cradle to the cave: ring complexes in the life of a protein. Science 268:523-524.
56. York, I. A., C. Roop, D. W. Andrews, S. R. Riddell, F. L. Grahm, and D. C. Johnson. 1994. A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes. Cell 77:525-535.
57. Zervos, A. S., J. Gyuris, and R. Brent. 1993. Mxil, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell 72:223-232.
58. Zoulim, F., J. Saputelli, and C. Seeger. 1994. Woodchuck hepatitis virus X protein is required for viral infection in vivo. J. Virol. 68:2026-2030.