The effect of GIRK2wv on neurite growth, protein expression, and viability in the CNS-derived neuronal cell line, Cath.a-differentiated

Neuroscience

Volumn 134, Issue 1, 2005, Pages 21-32

  Schein, J C ^a,b   Wang, J K T ^a,c   Roffler Tarlov, S K ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SanBio Inc   (United States)

^c EnVivo Pharmaceuticals   (United States)

Author keywords

CAD; Cell death; Girk2; Kir2.3; Neurodegeneration; Weaver

Indexed keywords

CATECHOLAMINE; COMPLEMENTARY DNA; DIZOCILPINE; INWARDLY RECTIFYING POTASSIUM CHANNEL; SODIUM ION;

ARTICLE; CELL CULTURE; CELL DEATH; CELL LINE; CELL PROLIFERATION; CELL VIABILITY; CENTRAL NERVOUS SYSTEM; DEPOLARIZATION; GENE MUTATION; GENETIC TRANSFECTION; HOMEOSTASIS; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT GIRK2; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.3; MORPHOLOGY; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; PRIORITY JOURNAL; PROTEIN EXPRESSION; SODIUM TRANSPORT; WILD TYPE;

ANIMALS; BLOTTING, WESTERN; CELL COUNT; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE; CENTRAL NERVOUS SYSTEM; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; IMMUNOHISTOCHEMISTRY; MICE; MICE, NEUROLOGIC MUTANTS; NEURITES; NEURONS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; TIME FACTORS; TRANSFECTION;

EID: 21744441470     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2005.03.043     Document Type: Article

References (40)

1. C. Adelbrecht, Y. Agid, R. Raisman-Vozari Effect of weaver mutation on the expression of dopamine membrane transporter, tyrosine hydroxylase and vesicular monoamine transporter in dopaminergic neurons of the substantia nigra and the ventral tegmental area Mol Brain Res 43 1996 291 300
2. C. Adelbrecht, M. Murer, I. Lauritzen, F. Lesage, M. Ladzunski, Y. Agid, R. Raisman-Vozari An immunocytochemical study of a G-protein-gated inward rectifier K+ channel (GIRK2) in the weaver mouse mesencephalon Neuroreport 8 1997 969 974
3. S.H. Chen, P. Ehrhard, D. Goldowitz, R.J. Smeyne Developmental expression of the GIRK family of inward rectifying potassium channels implications for abnormalities in the weaver mutant mouse Brain Res 778 1997 251 264
4. N. Dascal, N.F. Lim, W. Schreibmayer, W. Wang, N. Davidson, H.A. Lester Expression of an atrial G-protein-activated potassium channel in Xenopus oocytes Proc Natl Acad Sci U S A 90 1993 6596 6600
5. C.A. Doupnik, N. Davidson, H.A. Lester The inward rectifier potassium channel family Curr Opin Neurobiol 5 1995 268 277
6. A. Graybiel, K. Ohta, S. Roffler-Tarlov Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. I. Gradients and compartments J Neurosci 10 1990 720 733
7. E. Guatteo, F.R. Fusco, P. Giacomini, G. Bernardi, N.B. Mercuri The weaver mutation reverses the function of dopamine and GABA in mouse dopaminergic neurons J Neurosci 20 2000 6013 6020
8. K. Herrup, E. Trenkner Regional differences in cytoarchitecture of the weaver cerebellum suggest a new model for weaver gene action Neuroscience 23 3 1987 871 885
9. P. Hou, S. Yan, W. Tang, D.J. Nelson The inwardly rectifying K(+) channel subunit GIRK1 rescues the GIRK2 weaver phenotype J Neurosci 19 1999 8327 8336
10. + channel Kir2.3 is localized at the postsynaptic membrane of excitatory synapses Am J Physiol Cell Physiol 282 2002 C1396 C1403
11. L.Y. Jan, Y.N. Jan Voltage-gated and inwardly rectifying potassium channels J Physiol 505 1997 267 282
12. + channel mRNAs are differentially expressed in the adult rat brain J Neurosci 16 1996 3559 3570
13. P. Kofuji, M. Hofer, K. Millen, J. Millonig, N. Davidson, H. Lester, M. Hatten Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells Neuron 16 1996 941 952
14. Y. Kubo, E. Reuveny, P.A. Slesinger, Y.N. Jan, L.Y. Jan Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel Nature 364 1993 802 806
15. I. Lauritzen, J. De Weille, C. Adelbrecht, F. Lesage, G. Murer, R. Raisman-Vozari, M. Lazdunski Comparative expression of the inward rectifier K+ channel GIRK2 in the cerebellum of normal and weaver mutant mice Brain Res 753 1997 8 17
16. F. Lesage, F. Duprat, M. Fink, E. Guillemare, T. Coppola, M. Lazdunski, J.P. Hugnot Cloning provides evidence for a family of inward rectifier and G-protein coupled K+ channels in the brain FEBS Lett 353 1994 37 42
17. Y. Liao, Y. Jan, L. Jan Heteromultimerization of G-protein-gated inwardly rectifying K+ channel proteins GIRK1 and GIRK2 and their altered expression in weaver brain J Neurosci 16 1996 7137 7150
18. B. Liss, A. Neu, J. Roeper The weaver mouse gain-of-function phenotype of dopaminergic midbrain neurons is determined by coactivation of wvGirk2 and K-ATP channels J Neurosci 19 1999 8839 8848
19. B. Navarro, M. Kennedy, B. Velimirovic, D. Bhat, A. Peterson, D. Clapham Nonselective and G betagamma-insensitive weaver K+ channels Science 272 1996 1950 1953
20. C.G. Nichols, A.N. Lopatin Inward rectifier potassium channels Annu Rev Physiol 59 1997 171 191
21. T. Oo, R. Blazeski, S. Harrison, C. Henchcliffe, C. Mason, S. Roffler-Tarlov, R. Burke Neuron death in the substantia nigra of weaver mouse occurs late in development and is not apoptotic J Neurosci 16 1996 6134 6145
22. J.B. Pasuit, Z. Li, E.V. Kuzhikandathil Multi-modal regulation of endogenous D1 dopamine receptor expression and function in the CAD catecholaminergic cell line J Neurochem 89 2004 1508 1519
23. N. Patil, D. Cox, D. Bhat, M. Faham, R. Myers, A. Peterson A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation Nat Genet 11 1995 126 129
24. F. Perier, C.M. Radeke, C.A. Vandenberg Primary structure and characterization of a small-conductance inwardly rectifying potassium channel from human hippocampus Proc Natl Acad Sci U S A 91 13 1994 6240 6244
25. + channels via phospholipase C and protein kinase C-δ in reactive astrocytes from adult rat brain J Biol Chem 277 2002 1974 1980
26. G. Peterson A simplification of the protein assay method of Lowry et al., which is more generally applicable Anal Biochem 83 1977 346 356
27. Y. Qi, J. Wang, M. McMillian, D. Chikaraishi Characterization of a CNS cell line, CAD, in which morphological differentiation is initiated by serum deprivation J Neurosci 17 1997 1217 1225
28. P. Rakic, R. Sidman Sequence of developmental abnormalities leading to granule cell deficit in cerebellar cortex of weaver mutant mice J Comp Neurol 152 1973 103 132
29. Z. Rezai, C. Yoon Abnormal rate of granule cell migration in the cerebellum of "Weaver" mutant mice Dev Biol 29 1972 17 26
30. S. Roffler-Tarlov, B. Martin, A. Graybiel, J. Kauer Cell death in the midbrain of the murine mutation weaver J Neurosci 16 1996 1819 1826
31. P. Rossi, G. De Filippi, S. Armano, V. Taglietti, E. D'Angelo The weaver mutation causes a loss of inward rectifier current regulation in premigratory granule cells of the mouse cerebellum J Neurosci 18 1998 3537 3547
32. J. Schein, D. Hunter, S. Roffler-Tarlov Girk2 expression in the ventral midbrain, cerebellum, and olfactory bulb and its relationship to the murine mutation weaver Dev Biol 204 1998 432 450
33. S. Silverman, P. Kofuji, D. Dougherty, N. Davidson, H. Lester A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation Proc Natl Acad Sci U S A 93 1996 15429 15434
34. P. Slesinger, N. Patil, Y. Liao, Y. Jan, L. Jan, D. Cox Functional effects of the mouse weaver mutation on G protein-gated inwardly rectifying K+ channels Neuron 16 1996 321 331
35. P. Slesinger, M. Stoffel, Y. Jan, L. Jan Defective γ-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice Proc Natl Acad Sci U S A 94 1997 12210 12217
36. R. Smeyne, D. Goldowitz Development and death of external granular layer cells in the weaver mouse cerebellum a quantitative study J Neurosci 9 1989 1608 1620
37. D. Surmeier, P. Mermelstein, D. Goldowitz The weaver mutation of GIRK2 results in a loss of inwardly rectifying K+ current in cerebellar granule cells Proc Natl Acad Sci U S A 93 1996 11191 11195
38. Y. Tong, J. Wei, S. Zhang, J. Strong, S. Dlouhy, M. Hodes, B. Ghetti, L. Yu The weaver mutation changes the ion selectivity of the affected inwardly rectifying potassium channel GIRK2 FEBS Lett 390 1996 63 68
39. L. Triarhou, J. Norton, B. Ghetti Mesencephalic dopamine cell deficit involves area A8, A9, and A10 in weaver mutant mouse Exp Brain Res 9 1988 256 265
40. S. Tucker, M. Pessia, A. Moorhouse, F. Gribble, F. Ashcroft, J. Maylie, J. Adelman Heteromeric channel formation and Ca(+)-free media reduce the toxic effect of the weaver Kir 3.2 allele FEBS Lett 390 1996 253 257