-
1
-
-
0032953097
-
Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance - A population-based twin study
-
Poulsen P, Kyvik KO, Vaag A, Beck-Nielsen H.- Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance-a population-based twin study. Diabetologia, 1999, 42, 139-145.
-
(1999)
Diabetologia
, vol.42
, pp. 139-145
-
-
Poulsen, P.1
Kyvik, K.O.2
Vaag, A.3
Beck-Nielsen, H.4
-
2
-
-
12344279952
-
Genetic factors in type 2 diabetes: The end of the beginning?
-
O'Rahilly S, Barroso I, Wareham NJ- Genetic factors in type 2 diabetes: the end of the beginning? Science, 2005, 307, 370-373.
-
(2005)
Science
, vol.307
, pp. 370-373
-
-
O'Rahilly, S.1
Barroso, I.2
Wareham, N.J.3
-
3
-
-
0033772073
-
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
-
Horikawa Y, Oda N, Cox NJ, et al.- Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet, 2000, 26, 163-175.
-
(2000)
Nat Genet
, vol.26
, pp. 163-175
-
-
Horikawa, Y.1
Oda, N.2
Cox, N.J.3
-
4
-
-
0035856017
-
Diet, lifestyle, and the risk of type 2 diabetes mellitus in women
-
Hu FB, Manson JE, Stampfer MJ, et al.- Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. N Engl J Med, 2001, 345, 790-797.
-
(2001)
N Engl J Med
, vol.345
, pp. 790-797
-
-
Hu, F.B.1
Manson, J.E.2
Stampfer, M.J.3
-
5
-
-
0015011783
-
Influence of nutritional factors on prevalence of diabetes
-
West KM, Kalbfleisch JM.- Influence of nutritional factors on prevalence of diabetes. Diabetes, 1971, 20, 99-108.
-
(1971)
Diabetes
, vol.20
, pp. 99-108
-
-
West, K.M.1
Kalbfleisch, J.M.2
-
6
-
-
0035856943
-
Diabetes mellitus and genetically programmed defects in beta-cell function
-
Bell GI, Polonsky KS.- Diabetes mellitus and genetically programmed defects in beta-cell function. Nature, 2001, 414, 788-791.
-
(2001)
Nature
, vol.414
, pp. 788-791
-
-
Bell, G.I.1
Polonsky, K.S.2
-
7
-
-
0019810028
-
Physiologic evaluation of factors controlling glucose tolerance in man: Measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose
-
Bergman RN, Phillips LS, Cobelli C.- Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. J Clin Invest, 1981, 68, 1456-1467.
-
(1981)
J Clin Invest
, vol.68
, pp. 1456-1467
-
-
Bergman, R.N.1
Phillips, L.S.2
Cobelli, C.3
-
8
-
-
0027375768
-
Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function
-
Kahn SE, Prigeon RL, McCulloch DK, et al.- Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function. Diabetes, 1993, 42, 1663-1672.
-
(1993)
Diabetes
, vol.42
, pp. 1663-1672
-
-
Kahn, S.E.1
Prigeon, R.L.2
McCulloch, D.K.3
-
9
-
-
0029775612
-
Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors
-
Clausen JO, Borch-Johnsen K, Ibsen H, et al.- Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors. J Clin Invest, 1996, 98, 1195-1209.
-
(1996)
J Clin Invest
, vol.98
, pp. 1195-1209
-
-
Clausen, J.O.1
Borch-Johnsen, K.2
Ibsen, H.3
-
10
-
-
0037382514
-
Glucose allostasis
-
Stumvoll M, Tataranni PA, Stefan N, et al.- Glucose allostasis. Diabetes, 2003, 52, 903-909.
-
(2003)
Diabetes
, vol.52
, pp. 903-909
-
-
Stumvoll, M.1
Tataranni, P.A.2
Stefan, N.3
-
11
-
-
0032740874
-
Walking compared with vigorous physical activity and risk of type 2 diabetes in women: A prospective study
-
Hu FB, Sigal RJ, Rich-Edwards JW, et al.- Walking compared with vigorous physical activity and risk of type 2 diabetes in women: a prospective study. JAMA, 1999, 282, 1433-1439.
-
(1999)
JAMA
, vol.282
, pp. 1433-1439
-
-
Hu, F.B.1
Sigal, R.J.2
Rich-Edwards, J.W.3
-
12
-
-
0026772772
-
Type 2 (non-insulin-dependent) diabetes mellitus: The thrifty phenotype hypothesis
-
Hales CN, Barker DJ.- Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia, 1992, 35, 595-601.
-
(1992)
Diabetologia
, vol.35
, pp. 595-601
-
-
Hales, C.N.1
Barker, D.J.2
-
13
-
-
19944432769
-
Genetic regulation of birth weight and fasting glucose by a common polymorphism in the islet cell promoter of the glucokinase gene
-
Weedon MN, Frayling TM, Shields B, et al.- Genetic regulation of birth weight and fasting glucose by a common polymorphism in the islet cell promoter of the glucokinase gene. Diabetes, 2005, 54, 576-581.
-
(2005)
Diabetes
, vol.54
, pp. 576-581
-
-
Weedon, M.N.1
Frayling, T.M.2
Shields, B.3
-
14
-
-
70349566593
-
Diabetes mellitus:a "thrifty" genotype rendered detrimental by "progress"?
-
Neel JV.- Diabetes mellitus:a "thrifty" genotype rendered detrimental by "progress"? Am JHum Genet, 1962, 14, 353-362.
-
(1962)
Am JHum Genet
, vol.14
, pp. 353-362
-
-
Neel, J.V.1
-
15
-
-
0019372096
-
Diabetes incidence in Pima Indians: Contributions of obesity and parental diabetes
-
Knowler WC, Pettitt DJ, Savage PJ, Bennett PH.} Diabetes incidence in Pima Indians: contributions of obesity and parental diabetes. Am J Epidemiol, 1981, 113, 144-156.
-
(1981)
Am J Epidemiol
, vol.113
, pp. 144-156
-
-
Knowler, W.C.1
Pettitt, D.J.2
Savage, P.J.3
Bennett, P.H.4
-
16
-
-
0028809238
-
Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent diabetes mellitus
-
Rothman DL, Magnusson I, Cline G, et al.- Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent diabetes mellitus. Proc Natl Acad Sci USA, 1995, 92, 983-987.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 983-987
-
-
Rothman, D.L.1
Magnusson, I.2
Cline, G.3
-
17
-
-
0033595121
-
Glucose transporters and insulin action-implications for insulin resistance and diabetes mellitus
-
Shepherd PR, Kahn BB.- Glucose transporters and insulin action-implications for insulin resistance and diabetes mellitus. N Engl J Med, 1999, 341, 248-257.
-
(1999)
N Engl J Med
, vol.341
, pp. 248-257
-
-
Shepherd, P.R.1
Kahn, B.B.2
-
18
-
-
0032764784
-
Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: A 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents
-
Perseghin G, Scifo P, De Cobelli F, et al.- Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. Diabetes, 1999, 48, 1600-1606.
-
(1999)
Diabetes
, vol.48
, pp. 1600-1606
-
-
Perseghin, G.1
Scifo, P.2
De Cobelli, F.3
-
19
-
-
1642377274
-
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
-
Petersen KF, Dufour S, Befroy D, et al.- Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med, 2004, 350, 664-667.
-
(2004)
N Engl J Med
, vol.350
, pp. 664-667
-
-
Petersen, K.F.1
Dufour, S.2
Befroy, D.3
-
20
-
-
0038025371
-
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
-
Petersen KF, Befroy D, Dufour S, et al.- Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science, 2003, 300, 1140-1142.
-
(2003)
Science
, vol.300
, pp. 1140-1142
-
-
Petersen, K.F.1
Befroy, D.2
Dufour, S.3
-
21
-
-
0023640773
-
In vivo insulin action is familial characteristic in nondiabetic Pima Indians
-
Lillioja S, Mott DM, Zawadzki JK, et al.- In vivo insulin action is familial characteristic in nondiabetic Pima Indians. Diabetes, 1987, 36, 1329-1335.
-
(1987)
Diabetes
, vol.36
, pp. 1329-1335
-
-
Lillioja, S.1
Mott, D.M.2
Zawadzki, J.K.3
-
22
-
-
0026637926
-
Familial clustering of insulin sensitivity
-
Martin BC, Warram JH, Rosner B, et al.- Familial clustering of insulin sensitivity. Diabetes, 1992, 41, 850-854.
-
(1992)
Diabetes
, vol.41
, pp. 850-854
-
-
Martin, B.C.1
Warram, J.H.2
Rosner, B.3
-
23
-
-
12144273136
-
Heritability of insulin secretion, peripheral and hepatic insulin action, and intracellular glucose partitioning in young and old Danish twins
-
Poulsen P, Levin K, Petersen I, et al.- Heritability of insulin secretion, peripheral and hepatic insulin action, and intracellular glucose partitioning in young and old Danish twins. Diabetes, 2005, 54, 275-283.
-
(2005)
Diabetes
, vol.54
, pp. 275-283
-
-
Poulsen, P.1
Levin, K.2
Petersen, I.3
-
24
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman GI.- Cellular mechanisms of insulin resistance. J Clin Invest, 2000, 106, 171-176.
-
(2000)
J Clin Invest
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
25
-
-
0342314436
-
Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients
-
Ryysy L, Hakkinen AM, Goto T, et al.- Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients. Diabetes, 2000, 49, 749-758.
-
(2000)
Diabetes
, vol.49
, pp. 749-758
-
-
Ryysy, L.1
Hakkinen, A.M.2
Goto, T.3
-
26
-
-
0026801899
-
Impaired insulin-mediated skeletal muscle blood flow in patients with NIDDM
-
Laakso M, Edelman SV, Brechtel G, Baron AD.- Impaired insulin-mediated skeletal muscle blood flow in patients with NIDDM. Diabetes, 1992, 41, 1076-1083.
-
(1992)
Diabetes
, vol.41
, pp. 1076-1083
-
-
Laakso, M.1
Edelman, S.V.2
Brechtel, G.3
Baron, A.D.4
-
27
-
-
0023951171
-
Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes
-
O'Rahilly S, Turner RC, Matthews DR.- Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes. N Engl J Med. 1988, 318, 1225-1230.
-
(1988)
N Engl J Med
, vol.318
, pp. 1225-1230
-
-
O'Rahilly, S.1
Turner, R.C.2
Matthews, D.R.3
-
28
-
-
0019429337
-
Insulin secretion in diabetes mellitus
-
Pfeifer MA, Halter JB, Porte D Jr.- Insulin secretion in diabetes mellitus. Am J Med, 1981, 70, 579-588.
-
(1981)
Am J Med
, vol.70
, pp. 579-588
-
-
Pfeifer, M.A.1
Halter, J.B.2
Porte Jr., D.3
-
29
-
-
0021751981
-
Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus
-
Ward WK, Bolgiano DC, McKnight B, et al.- Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus. J Clin Invest, 1984, 74, 1318-1328.
-
(1984)
J Clin Invest
, vol.74
, pp. 1318-1328
-
-
Ward, W.K.1
Bolgiano, D.C.2
McKnight, B.3
-
30
-
-
0025268864
-
Disproportionately elevated proinsulin in Pima Indians with noninsulin-dependent diabetes mellitus
-
Saad MF, Kahn SE, Nelson RG, et al.- Disproportionately elevated proinsulin in Pima Indians with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab, 1990, 70, 1247-1253.
-
(1990)
J Clin Endocrinol Metab
, vol.70
, pp. 1247-1253
-
-
Saad, M.F.1
Kahn, S.E.2
Nelson, R.G.3
-
31
-
-
0026043872
-
Prolonged maximal stimulation of insulin secretion in healthy subjects does not provoke preferential release of proinsulin
-
Nauck MA, Siegel EG, Creutzfeldt W.- Prolonged maximal stimulation of insulin secretion in healthy subjects does not provoke preferential release of proinsulin. Pancreas, 1991, 6, 645-652.
-
(1991)
Pancreas
, vol.6
, pp. 645-652
-
-
Nauck, M.A.1
Siegel, E.G.2
Creutzfeldt, W.3
-
32
-
-
0029092780
-
Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus
-
Ehrmann DA, Sturis J, Byrne MM, et al.- Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus. J Clin Invest, 1995, 96, 520-527.
-
(1995)
J Clin Invest
, vol.96
, pp. 520-527
-
-
Ehrmann, D.A.1
Sturis, J.2
Byrne, M.M.3
-
33
-
-
0029001526
-
Defects in insulin secretion and action in women with a history of gestational diabetes
-
Ryan EA, Imes S, Liu D, McManus R, et al.- Defects in insulin secretion and action in women with a history of gestational diabetes. Diabetes, 1995, 44, 506-512.
-
(1995)
Diabetes
, vol.44
, pp. 506-512
-
-
Ryan, E.A.1
Imes, S.2
Liu, D.3
McManus, R.4
-
34
-
-
12244299450
-
Beta-cell function in subjects spanning the range from normal glucose tolerance to overt diabetes: A new analysis
-
Ferrannini E, Gastaldelli A, Miyazaki Y, et al.- Beta-cell function in subjects spanning the range from normal glucose tolerance to overt diabetes: a new analysis. J Clin Endocrinol Metab, 2005, 90, 493-500.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 493-500
-
-
Ferrannini, E.1
Gastaldelli, A.2
Miyazaki, Y.3
-
35
-
-
0028817815
-
U.K. prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: A progressive disease
-
U.K. Prospective Diabetes Study Group.- U.K. prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. Diabetes. 1995, 44, 1249-1258.
-
(1995)
Diabetes
, vol.44
, pp. 1249-1258
-
-
-
36
-
-
0037219411
-
β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes
-
Butler AE, Janson J, Bonner-Weir S, et al.- β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes. Diabetes, 2003, 52, 102-110.
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
-
37
-
-
12344323484
-
Type 2 diabetes-a matter of beta-cell life and death?
-
Rhodes CJ.- Type 2 diabetes-a matter of beta-cell life and death? Science, 2005, 307, 380-384.
-
(2005)
Science
, vol.307
, pp. 380-384
-
-
Rhodes, C.J.1
-
38
-
-
4043171124
-
Islet amyloid: A critical entity in the pathogenesis of type 2 diabetes
-
Hull RL, Westermark GT, Westermark P, Kahn SE.- Islet amyloid: A critical entity in the pathogenesis of type 2 diabetes. J Clin Endocrinol Metab, 2004, 89, 3629-3643.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 3629-3643
-
-
Hull, R.L.1
Westermark, G.T.2
Westermark, P.3
Kahn, S.E.4
-
39
-
-
0036738398
-
Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets
-
Maedler K, Sergeev P, Ris F, Oberholzer J, et al.- Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets. J Clin Invest, 2002, 110, 851-860.
-
(2002)
J Clin Invest
, vol.110
, pp. 851-860
-
-
Maedler, K.1
Sergeev, P.2
Ris, F.3
Oberholzer, J.4
-
40
-
-
0033524937
-
Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes
-
Kulkarni RN, Bruning JC, Winnay JN, et al.- Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell, 1999, 96, 329-339.
-
(1999)
Cell
, vol.96
, pp. 329-339
-
-
Kulkarni, R.N.1
Bruning, J.C.2
Winnay, J.N.3
-
41
-
-
0020417387
-
Endocrine-metabolic relationships in patients with leprechaunism
-
Elders MJ, Schedewie HK, Olefsky J, et al.- Endocrine-metabolic relationships in patients with leprechaunism. J Natl Med Assoc, 1982, 74, 1195-1210.
-
(1982)
J Natl Med Assoc
, vol.74
, pp. 1195-1210
-
-
Elders, M.J.1
Schedewie, H.K.2
Olefsky, J.3
-
42
-
-
0032742992
-
The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
-
Weyer C, Bogardus C, Mott DM, Pratley RE.- The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest, 1999, 104, 787-794.
-
(1999)
J Clin Invest
, vol.104
, pp. 787-794
-
-
Weyer, C.1
Bogardus, C.2
Mott, D.M.3
Pratley, R.E.4
|