Preclinical pharmacology of epothilone D, a novel tubulin-stabilizing antitumor agent

Cancer Chemotherapy and Pharmacology

Volumn 56, Issue 3, 2005, Pages 255-260

  Wang, Hui ^a   Wang, Zhi ^a   Wang, Shuyi ^a   Li, Mao ^a   Nan, Li ^a   Rhie, Julie K ^a   Covey, Joseph M ^b   Zhang, Ruiwen ^a   Hill, Donald L ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Epothilone D; HPLC; Metabolism; Pharmacokinetics; Protein binding

Indexed keywords

ANTINEOPLASTIC AGENT; EPOTHILONE D; TUBULIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DOG; DOSE RESPONSE; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG PROTEIN BINDING; DRUG STABILITY; GUINEA PIG; HAMSTER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN;

ANIMALS; ANTINEOPLASTIC AGENTS; DOGS; DRUG EVALUATION, PRECLINICAL; DRUG STABILITY; EPOTHILONES; GUINEA PIGS; HUMANS; MALE; MICE; MICE, INBRED STRAINS; MICROSOMES, LIVER; PROTEIN BINDING; RATS; SPECIES SPECIFICITY;

EID: 21744438121     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-004-0965-0     Document Type: Article

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