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Volumn 66, Issue 12, 2001, Pages 4369-4378
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On the interactivity of complex synthesis and tumor pharmacology in the drug discovery process: Total synthesis and comparative in vivo evaluations of the 15-Aza epothilones
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Author keywords
[No Author keywords available]
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Indexed keywords
CONVERGENT STRATEGIES;
SYNTHESIS (CHEMICAL);
TUMORS;
PHARMACODYNAMICS;
12,13 DESOXYEPOTHILONE B;
12,13 DESOXYEPOTHILONE F;
12,13,15 DESOXY 15 AZAEPOTHILONE B;
EPOTHILONE B;
EPOTHILONE DERIVATIVE;
IXABEPILONE;
UNCLASSIFIED DRUG;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
CONTROLLED STUDY;
DRUG POTENCY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
STRUCTURE ANALYSIS;
ANIMALS;
ANTINEOPLASTIC AGENTS;
DRUG SCREENING ASSAYS, ANTITUMOR;
EPOTHILONES;
EPOXY COMPOUNDS;
HUMANS;
K562 CELLS;
MICE;
MICE, NUDE;
NEOPLASM TRANSPLANTATION;
SPECTRUM ANALYSIS;
THIAZOLES;
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EID: 0035874737
PISSN: 00223263
EISSN: None
Source Type: Journal
DOI: 10.1021/jo010275c Document Type: Article |
Times cited : (55)
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References (32)
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