메뉴 건너뛰기




Volumn 114, Issue 2-3, 2003, Pages 109-114

Behavioural analysis of melanin-concentrating hormone in rats: Evidence for orexigenic and anxiolytic properties

Author keywords

Anxiety; Body temperature; Exploratory behaviour; Food intake; Locomotor activity; Thermoregulation

Indexed keywords

ANXIOLYTIC AGENT; APPETITE STIMULANT; MELANIN CONCENTRATING HORMONE; NEUROPEPTIDE;

EID: 0038460899     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(03)00114-9     Document Type: Article
Times cited : (55)

References (36)
  • 1
    • 0022294711 scopus 로고
    • Immunohistochemical localization of a melanin concentrating hormone-like peptide in the rat brain
    • Skofitsch G., Jacobowitz D.M., Zamir N. Immunohistochemical localization of a melanin concentrating hormone-like peptide in the rat brain. Brain Res. Bull. 15:1985;635-649.
    • (1985) Brain Res. Bull. , vol.15 , pp. 635-649
    • Skofitsch, G.1    Jacobowitz, D.M.2    Zamir, N.3
  • 2
    • 0026766094 scopus 로고
    • The melanin-concentrating hormone system of the rat brain: An immuno- and hybridization histochemical characterization
    • Bittencourt J.C., Presse F., Arias C., Peto C., Vaughan J., Nahon J.L.et al. The melanin-concentrating hormone system of the rat brain: an immuno- and hybridization histochemical characterization. J. Comp. Neurol. 319:1992;218-245.
    • (1992) J. Comp. Neurol. , vol.319 , pp. 218-245
    • Bittencourt, J.C.1    Presse, F.2    Arias, C.3    Peto, C.4    Vaughan, J.5    Nahon, J.L.6
  • 3
    • 0033566128 scopus 로고    scopus 로고
    • Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1
    • Chambers J., Ames R.S., Bergsma D., Muir A., Fitzgerald L.R., Hervieu G.et al. Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1. Nature. 400:1999;261-265.
    • (1999) Nature , vol.400 , pp. 261-265
    • Chambers, J.1    Ames, R.S.2    Bergsma, D.3    Muir, A.4    Fitzgerald, L.R.5    Hervieu, G.6
  • 4
    • 0033566084 scopus 로고    scopus 로고
    • Molecular characterization of the melanin-concentrating-hormone receptor
    • Saito Y., Nothacker H.P., Wang Z., Lin S.H., Leslie F., Civelli O. Molecular characterization of the melanin-concentrating-hormone receptor. Nature. 400:1999;265-269.
    • (1999) Nature , vol.400 , pp. 265-269
    • Saito, Y.1    Nothacker, H.P.2    Wang, Z.3    Lin, S.H.4    Leslie, F.5    Civelli, O.6
  • 5
    • 0033194242 scopus 로고    scopus 로고
    • The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor
    • Lembo P.M., Grazzini E., Cao J., Hubatsch D.A., Pelletier M., Hoffert C.et al. The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor. Nat. Cell Biol. 1:1999;267-271.
    • (1999) Nat. Cell Biol. , vol.1 , pp. 267-271
    • Lembo, P.M.1    Grazzini, E.2    Cao, J.3    Hubatsch, D.A.4    Pelletier, M.5    Hoffert, C.6
  • 6
    • 0033546693 scopus 로고    scopus 로고
    • Isolation and identification of melanin-concentrating hormone as the endogenous ligand of the SLC-1 receptor
    • Shimomura Y., Mori M., Sugo T., Ishibashi Y., Abe M., Kurokawa T.et al. Isolation and identification of melanin-concentrating hormone as the endogenous ligand of the SLC-1 receptor. Biochem. Biophys. Res. Commun. 261:1999;622-626.
    • (1999) Biochem. Biophys. Res. Commun. , vol.261 , pp. 622-626
    • Shimomura, Y.1    Mori, M.2    Sugo, T.3    Ishibashi, Y.4    Abe, M.5    Kurokawa, T.6
  • 7
    • 0344604512 scopus 로고    scopus 로고
    • Identification of melanin concentrating hormone (MCH) as the natural ligand for the orphan somatostatin-like receptor 1 (SLC-1)
    • Bachner D., Kreienkamp H., Weise C., Buck F., Richter D. Identification of melanin concentrating hormone (MCH) as the natural ligand for the orphan somatostatin-like receptor 1 (SLC-1). FEBS Lett. 457:1999;522-524.
    • (1999) FEBS Lett. , vol.457 , pp. 522-524
    • Bachner, D.1    Kreienkamp, H.2    Weise, C.3    Buck, F.4    Richter, D.5
  • 8
    • 0035827647 scopus 로고    scopus 로고
    • Molecular cloning and functional characterization of MCH2, a novel human MCH receptor
    • Hill J., Duckworth M., Murdock P., Rennie G., Sabido-David C., Ames R.S.et al. Molecular cloning and functional characterization of MCH2, a novel human MCH receptor. J. Biol. Chem. 276:2001;20125-20129.
    • (2001) J. Biol. Chem. , vol.276 , pp. 20125-20129
    • Hill, J.1    Duckworth, M.2    Murdock, P.3    Rennie, G.4    Sabido-David, C.5    Ames, R.S.6
  • 9
    • 0034807075 scopus 로고    scopus 로고
    • Cloning of a novel G protein-coupled receptor, SLT, a subtype of the melanin-concentrating hormone receptor
    • Mori M., Harada M., Terao Y., Sugo T., Watanabe T., Shimomura Y.et al. Cloning of a novel G protein-coupled receptor, SLT, a subtype of the melanin-concentrating hormone receptor. Biochem. Biophys. Res. Commun. 283:2001;1013-1018.
    • (2001) Biochem. Biophys. Res. Commun. , vol.283 , pp. 1013-1018
    • Mori, M.1    Harada, M.2    Terao, Y.3    Sugo, T.4    Watanabe, T.5    Shimomura, Y.6
  • 10
    • 0035860811 scopus 로고    scopus 로고
    • Identification and pharmacological characterization of a novel human melanin-concentrating hormone receptor, mch-r2
    • Wang S., Behan J., O'Neill K., Weig B., Fried S., Laz T.et al. Identification and pharmacological characterization of a novel human melanin-concentrating hormone receptor, mch-r2. J. Biol. Chem. 276:2001;34664-34670.
    • (2001) J. Biol. Chem. , vol.276 , pp. 34664-34670
    • Wang, S.1    Behan, J.2    O'Neill, K.3    Weig, B.4    Fried, S.5    Laz, T.6
  • 11
    • 0035912709 scopus 로고    scopus 로고
    • Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R
    • Sailer A.W., Sano H., Zeng Z., McDonald T.P., Pan J., Pong S.S.et al. Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R. Proc. Natl. Acad. Sci. U. S. A. 98:2001;7564-7569.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 7564-7569
    • Sailer, A.W.1    Sano, H.2    Zeng, Z.3    McDonald, T.P.4    Pan, J.5    Pong, S.S.6
  • 13
    • 0036271227 scopus 로고    scopus 로고
    • Melanin-concentrating hormone receptor subtypes 1 and 2: Species-specific gene expression
    • Tan C.P., Sano H., Iwaasa H., Pan J., Sailer A.W., Hreniuk D.L.et al. Melanin-concentrating hormone receptor subtypes 1 and 2: species-specific gene expression. Genomics. 79:2002;785-792.
    • (2002) Genomics , vol.79 , pp. 785-792
    • Tan, C.P.1    Sano, H.2    Iwaasa, H.3    Pan, J.4    Sailer, A.W.5    Hreniuk, D.L.6
  • 14
    • 0035908285 scopus 로고    scopus 로고
    • Expression of the melanin-concentrating hormone (MCH) receptor mRNA in the rat brain
    • Saito Y., Cheng M., Leslie F.M., Civelli O. Expression of the melanin-concentrating hormone (MCH) receptor mRNA in the rat brain. J. Comp. Neurol. 435:2001;26-40.
    • (2001) J. Comp. Neurol. , vol.435 , pp. 26-40
    • Saito, Y.1    Cheng, M.2    Leslie, F.M.3    Civelli, O.4
  • 15
    • 0034005858 scopus 로고    scopus 로고
    • The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat
    • Hervieu G.J., Cluderay J.E., Harrison D., Meakin J., Maycox P., Nasir S.et al. The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat. Eur. J. Neurosci. 12:2000;1194-1216.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 1194-1216
    • Hervieu, G.J.1    Cluderay, J.E.2    Harrison, D.3    Meakin, J.4    Maycox, P.5    Nasir, S.6
  • 16
    • 13344279395 scopus 로고    scopus 로고
    • A role for melanin-concentrating hormone in the central regulation of feeding behaviour
    • Qu D., Ludwig D.S., Gammeltoft S., Piper M., Pelleymounter M.A., Cullen M.J.et al. A role for melanin-concentrating hormone in the central regulation of feeding behaviour. Nature. 380:1996;243-247.
    • (1996) Nature , vol.380 , pp. 243-247
    • Qu, D.1    Ludwig, D.S.2    Gammeltoft, S.3    Piper, M.4    Pelleymounter, M.A.5    Cullen, M.J.6
  • 17
    • 0031023301 scopus 로고    scopus 로고
    • Melanin-concentrating hormone acutely stimulates feeding, but chronic administration has no effect on body weight
    • Rossi M., Choi S.J., O'Shea D., Miyoshi T., Ghatei M.A., Bloom S.R. Melanin-concentrating hormone acutely stimulates feeding, but chronic administration has no effect on body weight. Endocrinology. 138:1997;351-355.
    • (1997) Endocrinology , vol.138 , pp. 351-355
    • Rossi, M.1    Choi, S.J.2    O'Shea, D.3    Miyoshi, T.4    Ghatei, M.A.5    Bloom, S.R.6
  • 19
  • 20
    • 0035134670 scopus 로고    scopus 로고
    • Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance
    • Ludwig D.S., Tritos N.A., Mastaitis J.W., Kulkarni R., Kokkotou E., Elmquist J.et al. Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. J. Clin. Invest. 107:2001;379-386.
    • (2001) J. Clin. Invest. , vol.107 , pp. 379-386
    • Ludwig, D.S.1    Tritos, N.A.2    Mastaitis, J.W.3    Kulkarni, R.4    Kokkotou, E.5    Elmquist, J.6
  • 21
    • 0037139340 scopus 로고    scopus 로고
    • The neurochemical characterisation of hypothalamic pathways projecting polysynaptically to brown adipose tissue in the rat
    • Oldfield B.J., Giles M.E., Watson A., Anderson C., Colvill L.M., McKinley M.J. The neurochemical characterisation of hypothalamic pathways projecting polysynaptically to brown adipose tissue in the rat. Neuroscience. 110:2002;515-526.
    • (2002) Neuroscience , vol.110 , pp. 515-526
    • Oldfield, B.J.1    Giles, M.E.2    Watson, A.3    Anderson, C.4    Colvill, L.M.5    McKinley, M.J.6
  • 22
    • 0003717437 scopus 로고    scopus 로고
    • The rat brain in stereotaxic coordinates
    • San Diego: Academic Press
    • Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 4th ed. 1998;Academic Press, San Diego.
    • (1998) 4th ed.
    • Paxinos, G.1    Watson, C.2
  • 23
    • 0015004136 scopus 로고
    • A simple and reliable conflict procedure for testing anti-anxiety agents
    • Vogel J.R., Beer B., Clody D.E. A simple and reliable conflict procedure for testing anti-anxiety agents. Psychopharmacologia. 21:1971;1-7.
    • (1971) Psychopharmacologia , vol.21 , pp. 1-7
    • Vogel, J.R.1    Beer, B.2    Clody, D.E.3
  • 24
    • 0343488556 scopus 로고    scopus 로고
    • Decreased experimental anxiety and voluntary ethanol consumption in rats following central but not basolateral amygdala lesions
    • Möller C., Wiklund L., Sommer W., Thorsell A., Heilig M. Decreased experimental anxiety and voluntary ethanol consumption in rats following central but not basolateral amygdala lesions. Brain Res. 760:1997;94-101.
    • (1997) Brain Res. , vol.760 , pp. 94-101
    • Möller, C.1    Wiklund, L.2    Sommer, W.3    Thorsell, A.4    Heilig, M.5
  • 25
    • 0025907631 scopus 로고
    • Photocell measurements of rat motor activity. A contribution to sensitivity and variation in behavioral observations
    • Ericson E., Samuelsson J., Ahlenius S. Photocell measurements of rat motor activity. A contribution to sensitivity and variation in behavioral observations. J. Pharmacol. Methods. 25:1991;111-122.
    • (1991) J. Pharmacol. Methods , vol.25 , pp. 111-122
    • Ericson, E.1    Samuelsson, J.2    Ahlenius, S.3
  • 26
    • 0028123540 scopus 로고
    • Antagonism by SCH 23390 of clozapine-induced hypothermia in the rat
    • Salmi P., Karlsson T., Ahlenius S. Antagonism by SCH 23390 of clozapine-induced hypothermia in the rat. Eur. J. Pharmacol. 253:1994;67-73.
    • (1994) Eur. J. Pharmacol. , vol.253 , pp. 67-73
    • Salmi, P.1    Karlsson, T.2    Ahlenius, S.3
  • 27
    • 0031697756 scopus 로고    scopus 로고
    • Functional interactions between melanin-concentrating hormone, neuropeptide Y, and anorectic neuropeptides in the rat hypothalamus
    • Tritos N.A., Vicent D., Gillette J., Ludwig D.S., Flier E.S., Maratos-Flier E. Functional interactions between melanin-concentrating hormone, neuropeptide Y, and anorectic neuropeptides in the rat hypothalamus. Diabetes. 47:1998;1687-1692.
    • (1998) Diabetes , vol.47 , pp. 1687-1692
    • Tritos, N.A.1    Vicent, D.2    Gillette, J.3    Ludwig, D.S.4    Flier, E.S.5    Maratos-Flier, E.6
  • 28
    • 0036701225 scopus 로고    scopus 로고
    • Cloning and characterization of rhesus monkey MCH-R1 and MCH-R2
    • Fried S., O'Neill K., Hawes B. Cloning and characterization of rhesus monkey MCH-R1 and MCH-R2. Peptides. 23:2002;1401.
    • (2002) Peptides , vol.23 , pp. 1401
    • Fried, S.1    O'Neill, K.2    Hawes, B.3
  • 29
    • 0032739396 scopus 로고    scopus 로고
    • Response to novelty after i.c.v. injection of melanin-concentrating hormone (MCH) in rats
    • Monzon M.E., De Barioglio S.R. Response to novelty after i.c.v. injection of melanin-concentrating hormone (MCH) in rats. Physiol. Behav. 67:1999;813-817.
    • (1999) Physiol. Behav. , vol.67 , pp. 813-817
    • Monzon, M.E.1    De Barioglio, S.R.2
  • 30
    • 0034973992 scopus 로고    scopus 로고
    • Anxiogenesis induced by nitric oxide synthase inhibition and anxiolytic effect of melanin-concentrating hormone (MCH) in rat brain
    • Monzon M.E., Varas M.M., De Barioglio S.R. Anxiogenesis induced by nitric oxide synthase inhibition and anxiolytic effect of melanin-concentrating hormone (MCH) in rat brain. Peptides. 22:2001;1043-1047.
    • (2001) Peptides , vol.22 , pp. 1043-1047
    • Monzon, M.E.1    Varas, M.M.2    De Barioglio, S.R.3
  • 31
    • 0029670663 scopus 로고    scopus 로고
    • Behavioral effects of alpha-MSH and MCH after central administration in the female rat
    • Gonzalez M.I., Vaziri S., Wilson C.A. Behavioral effects of alpha-MSH and MCH after central administration in the female rat. Peptides. 17:1996;171-177.
    • (1996) Peptides , vol.17 , pp. 171-177
    • Gonzalez, M.I.1    Vaziri, S.2    Wilson, C.A.3
  • 32
    • 0036341292 scopus 로고    scopus 로고
    • Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist
    • Borowsky B., Durkin M.M., Ogozalek K., Marzabadi M.R., DeLeon J., Heurich R.et al. Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist. Nat. Med. 8:2002;825-830.
    • (2002) Nat. Med. , vol.8 , pp. 825-830
    • Borowsky, B.1    Durkin, M.M.2    Ogozalek, K.3    Marzabadi, M.R.4    DeLeon, J.5    Heurich, R.6
  • 33
    • 0026026039 scopus 로고
    • Sex differences in animal tests of anxiety
    • Johnston A.L., File S.E. Sex differences in animal tests of anxiety. Physiol. Behav. 49:1991;245-250.
    • (1991) Physiol. Behav. , vol.49 , pp. 245-250
    • Johnston, A.L.1    File, S.E.2
  • 34
    • 0027385156 scopus 로고
    • Sex differences in anxiety behavior in rats: Role of gonadal hormones
    • Zimmerberg B., Farley M.J. Sex differences in anxiety behavior in rats: role of gonadal hormones. Physiol. Behav. 54:1993;1119-1124.
    • (1993) Physiol. Behav. , vol.54 , pp. 1119-1124
    • Zimmerberg, B.1    Farley, M.J.2
  • 35
    • 0030919781 scopus 로고    scopus 로고
    • Melanin-concentrating hormone (MCH) antagonizes the effects of alpha-MSH and neuropeptide E-I on grooming and locomotor activities in the rat
    • Sanchez M., Baker B.I., Celis M. Melanin-concentrating hormone (MCH) antagonizes the effects of alpha-MSH and neuropeptide E-I on grooming and locomotor activities in the rat. Peptides. 18:1997;393-396.
    • (1997) Peptides , vol.18 , pp. 393-396
    • Sanchez, M.1    Baker, B.I.2    Celis, M.3
  • 36
    • 0035714671 scopus 로고    scopus 로고
    • Correlation of increased grooming behavior and motor activity with alterations in nigrostriatal and mesolimbic catecholamines after alpha-melanotropin and neuropeptide glutamine-isoleucine injection in the rat ventral tegmental area
    • Sanchez M.S., Barontini M., Armando I., Celis M.E. Correlation of increased grooming behavior and motor activity with alterations in nigrostriatal and mesolimbic catecholamines after alpha-melanotropin and neuropeptide glutamine-isoleucine injection in the rat ventral tegmental area. Cell. Mol. Neurobiol. 21:2001;523-533.
    • (2001) Cell. Mol. Neurobiol. , vol.21 , pp. 523-533
    • Sanchez, M.S.1    Barontini, M.2    Armando, I.3    Celis, M.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.