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Volumn 13, Issue 1, 2005, Pages 101-108

Bis(ethyl)norspermine potentiates the apoptotic activity of the pure antiestrogen ICI 182780 in breast cancer cells

Author keywords

Antiestrogen; Bis(ethyl)norspermine; Breast cancer

Indexed keywords

ANTIESTROGEN; ANTINEOPLASTIC AGENT; CASP8 PROTEIN, HUMAN; CASPASE; CASPASE 8; DRUG DERIVATIVE; ESTRADIOL; FULVESTRANT; N(1),N(11) DIETHYLNORSPERMINE; N(1),N(11)-DIETHYLNORSPERMINE; POLYAMINE; PROTEIN BCL 2; SPERMINE;

EID: 21644450924     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.13.1.101     Document Type: Article
Times cited : (7)

References (49)
  • 1
    • 0141785350 scopus 로고    scopus 로고
    • Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: Insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype
    • DOI 10.1210/en.2003-0567
    • Frasor J, Danes JM, Komm B, Chang KC, Lyttle CR and Katzenellenbogen BS: Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of the proliferation and cell phenotype. Endocrinology 144: 4562-4574, 2003. (Pubitemid 37204856)
    • (2003) Endocrinology , vol.144 , Issue.10 , pp. 4562-4574
    • Frasor, J.1    Danes, J.M.2    Komm, B.3    Chang, K.C.N.4    Richard, L.C.5    Katzenellenbogen, B.S.6
  • 2
    • 0033429147 scopus 로고    scopus 로고
    • Role of proliferation and apoptosis in net growth rates of human breast cancer cells (MCF-7) treated with oestradiol and/or tamoxifen
    • Budtz PE: Role of proliferation and apoptosis in net growth rates of human breast cancer cells (MCF-7) treated with oestradiol and/or tamoxifen. Cell Prolif 32: 289-302, 1999.
    • (1999) Cell Prolif , vol.32 , pp. 289-302
    • Budtz, P.E.1
  • 3
    • 0031778177 scopus 로고    scopus 로고
    • Basic guide to the mechanisms of antiestrogen action
    • MacGregor JI and Jordan VC: Basic guide to the mechanisms of antiestrogen action. Pharmacol Rev 50: 151-196, 1998.
    • (1998) Pharmacol Rev , vol.50 , pp. 151-196
    • MacGregor, J.I.1    Jordan, V.C.2
  • 4
    • 2442433996 scopus 로고    scopus 로고
    • Nongenomic effects of 17β-estradiol - Diversity of membrane binding sites
    • DOI 10.1016/j.jsbmb.2004.01.004, PII S0960076004000408
    • Sak K and Everaus H: Nongenomic effects of 17β-estradiol-diversity of membrane binding sites. J Steroid Biochem Mol Biol 88: 323-335, 2004. (Pubitemid 38625597)
    • (2004) Journal of Steroid Biochemistry and Molecular Biology , vol.88 , Issue.4-5 , pp. 323-335
    • Sak, K.1    Everaus, H.2
  • 5
    • 0034286302 scopus 로고    scopus 로고
    • Tamoxifen: A personal retrospective
    • Jordan VC: Tamoxifen: a personal retrospective. Lancet Oncol 1: 43-49, 2000.
    • (2000) Lancet Oncol , vol.1 , pp. 43-49
    • Jordan, V.C.1
  • 6
    • 0033136349 scopus 로고    scopus 로고
    • New vs old fashioned oestradiol antagonists in mammary carcinoma: 'In vitro' and 'in vivo' pharmacological approaches
    • DOI 10.1006/phrs.1998.0437
    • De Cupis A, Schettini G and Favoni RE: New vs old fashioned estradiol antagonists in mammary carcinoma: in vitro and in vivo pharmacological approaches. Pharmacol Res 39: 335-344, 1999. (Pubitemid 29263900)
    • (1999) Pharmacological Research , vol.39 , Issue.5 , pp. 335-344
    • De Cupis, A.1    Schettini, G.2    Favoni, R.E.3
  • 7
    • 0029048753 scopus 로고
    • Gynecologic effects of tamoxifen and the association with endometrial carcinoma
    • Assikis VJ and Jordan VC: Gynecologic effects of tamoxifen and the association with endometrial carcinoma. Int J Gynaecol Obstet 49: 241-257, 1995.
    • (1995) Int J Gynaecol Obstet , vol.49 , pp. 241-257
    • Assikis, V.J.1    Jordan, V.C.2
  • 8
    • 2942565669 scopus 로고    scopus 로고
    • Overcoming endocrine therapy resistance by signal transduction inhibition
    • Ellis M: Overcoming endocrine therapy resistance by signal transduction inhibition. Oncologist 9 S3: 20-26, 2004.
    • (2004) Oncologist , vol.9 , Issue.S3 , pp. 20-26
    • Ellis, M.1
  • 9
    • 0034663421 scopus 로고    scopus 로고
    • ICI182780 (Faslodex): Development of a novel, 'pure' antiestrogen
    • Howell AOC, Morris C and Wakeling AE: ICI182780 (Faslodex): development of a novel, 'pure' antiestrogen. Cancer 89: 817-825, 2000.
    • (2000) Cancer , vol.89 , pp. 817-825
    • Howell, A.O.C.1    Morris, C.2    Wakeling, A.E.3
  • 10
    • 0029075872 scopus 로고
    • Comparison of the effects of the pure steroidal antiestrogens with those of tamoxifen in a model of human breast cancer
    • Osborne C, Coronado-Heinsohn ER and Hilsenbeck SG: Comparison of the effects of the pure steroidal antiestrogens with those of tamoxifen in a model of human breast cancer. J. Natl Cancer Inst 87: 746-750, 1995.
    • (1995) J. Natl Cancer Inst , vol.87 , pp. 746-750
    • Osborne, C.1    Coronado-Heinsohn, E.R.2    Hilsenbeck, S.G.3
  • 11
    • 0036909222 scopus 로고    scopus 로고
    • FDA drug approval summaries: Fulvestrant
    • DOI 10.1634/theoncologist.7-6-477
    • Bross PF, Cohen MH, Williams GA and Pazdur R: FDA drug approval summaries: fulvestrant. Oncologist 7: 477-480, 2002. (Pubitemid 36008996)
    • (2002) Oncologist , vol.7 , Issue.6 , pp. 477-480
    • Bross, P.F.1    Cohen, M.H.2    Williams, G.A.3    Pazdur, R.4
  • 12
    • 0024998124 scopus 로고
    • Polyamine involvement in basal and estradiol-stimulated insulin-like growth factor I secretion and action in breast cancer cells in culture
    • Glikman PL, Manni A, Bartholomew M and Demers L: Polyamine involvement in basal and estradiol-stimulated insulin-like growth factor I secretion and action in breast cancer cells in culture. J Steroid Biochem Mol Biol 37: 1-10, 1990. (Pubitemid 20385630)
    • (1990) Journal of Steroid Biochemistry and Molecular Biology , vol.37 , Issue.1 , pp. 1-10
    • Glikman, P.L.1    Manni, A.2    Bartholomew, M.3    Demers, L.4
  • 13
    • 0028265460 scopus 로고
    • Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: Therapeutic implications
    • Thomas T and Thomas TJ: Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: therapeutic implications. Breast Cancer Res Treat 29: 189-201, 1994. (Pubitemid 24112620)
    • (1994) Breast Cancer Research and Treatment , vol.29 , Issue.2 , pp. 189-201
    • Thomas, T.1    Thomas, T.J.2
  • 14
    • 0035099627 scopus 로고    scopus 로고
    • Polyamines in cell growth and cell death: Molecular mechanisms and therapeutic applications
    • Thomas T and Thomas TJ: Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications. Cell Mol Life Sci 58: 244-258, 2001. (Pubitemid 32217356)
    • (2001) Cellular and Molecular Life Sciences , vol.58 , Issue.2 , pp. 244-258
    • Thomas, T.1    Thomas, T.J.2
  • 16
    • 0029050287 scopus 로고
    • Increased frequency of spontaneous skin tumors in transgenic mice which overexpress ornithine decarboxylase
    • Megosh L, Gilmour SK, Rosson D, Soler AP, Blessing M, Sawicki JA and O'Brien TG: Increased frequency of spontaneous skin tumors in transgenic mice which overexpress ornithine decarboxylase. Cancer Res 55: 4205-4209, 1995.
    • (1995) Cancer Res , vol.55 , pp. 4205-4209
    • Megosh, L.1    Gilmour, S.K.2    Rosson, D.3    Soler, A.P.4    Blessing, M.5    Sawicki, J.A.6    O'Brien, T.G.7
  • 17
    • 0032766004 scopus 로고    scopus 로고
    • Prognostic value of ornithine decarboxylase and polyamines in human breast cancer: Correlation with clinicopathologic parameters
    • Canizares F, Salinas J, de las Heras M, Diaz J, Tovar I, Martinez P and Penafiel R: Prognostic value of ornithine decarboxylase and polyamines in human breast cancer: correlation with clinicopathologic parameters. Clin Cancer Res 5: 2035-2041, 1999. (Pubitemid 29399255)
    • (1999) Clinical Cancer Research , vol.5 , Issue.8 , pp. 2035-2041
    • Canizares, F.1    Salinas, J.2    De Las, H.M.3    Diaz, J.4    Tovar, I.5    Martinez, P.6    Penafiel, R.7
  • 18
    • 0035967111 scopus 로고    scopus 로고
    • Regulation of estrogenic and nuclear factor κB functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells
    • Shah N, Thomas TJ, Lewis JS, Klinge CM, Shirahata A, Gelinas C and Thomas T: Regulation of estrogenic and nuclear factor κB functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells. Oncogene 20: 1715-2179, 2001.
    • (2001) Oncogene , vol.20 , pp. 1715-2179
    • Shah, N.1    Thomas, T.J.2    Lewis, J.S.3    Klinge, C.M.4    Shirahata, A.5    Gelinas, C.6    Thomas, T.7
  • 20
    • 0026326057 scopus 로고
    • Variations in amplification and expression of the ornithine decarboxylase gene in human breast cancer cell lines
    • Thomas T, Kiang DT, Janne OA and Thomas TJ: Variations in amplification and expression of the ornithine decarboxylase gene in human breast cancer cell lines. Breast Cancer Res Treat 19: 257-267, 1991.
    • (1991) Breast Cancer Res Treat , vol.19 , pp. 257-267
    • Thomas, T.1    Kiang, D.T.2    Janne, O.A.3    Thomas, T.J.4
  • 23
    • 0024151667 scopus 로고
    • Regulation of polyamine biosynthetic activity by spermidine and spermine analogs-a novel antiproliferative strategy
    • Porter CW and Bergeron RJ: Regulation of polyamine biosynthetic activity by spermidine and spermine analogs-a novel antiproliferative strategy. Adv Exp Med Biol 250: 677-690, 1988.
    • (1988) Adv Exp Med Biol , vol.250 , pp. 677-690
    • Porter, C.W.1    Bergeron, R.J.2
  • 27
    • 0028288228 scopus 로고
    • Correlation between the inhibition of cell growth by bis(ethyl)polyamine analogues and the decrease in the function of mitochondria
    • He Y, Suzuki T, Kashiwagi K, Kusuma-Eguchi K, Shirahata A and Igarashi K: Correlation between the inhibition of cell growth by bis(ethyl)polyamine analogues and the decrease in the function of mitochondria. Eur J Biochem 221: 391-398, 1994. (Pubitemid 24120584)
    • (1994) European Journal of Biochemistry , vol.221 , Issue.1 , pp. 391-398
    • He, Y.1    Suzuki, T.2    Kashiwagi, K.3    Kusama-Eguchi, K.4    Shirahata, A.5    Igarashi, K.6
  • 28
    • 0029025470 scopus 로고
    • Inhibition of the growth of various human and mouse tumor cells by 1,15-bis(ethylamino)-4,8,12-triazapentadecane
    • Igarashi K, Koga K, He Y, Shimogori T, Ekimoto H, Kashiwagi K and Shirahata A: Inhibition of the growth of various human and mouse tumor cells by 1,15-bis(ethylamino)-4,8,12-triazapentadecane. Cancer Res 55: 2615-2619, 1995.
    • (1995) Cancer Res , vol.55 , pp. 2615-2619
    • Igarashi, K.1    Koga, K.2    He, Y.3    Shimogori, T.4    Ekimoto, H.5    Kashiwagi, K.6    Shirahata, A.7
  • 29
    • 0028205818 scopus 로고
    • Regulation of cyclin B1 by estradiol and polyamines in MCF-7 breast cancer cells
    • Thomas T and Thomas TJ: Regulation of cyclin B1 by estradiol and polyamines in MCF-7 breast cancer cells. Cancer Res 54: 1077-1084, 1994. (Pubitemid 24085466)
    • (1994) Cancer Research , vol.54 , Issue.4 , pp. 1077-1084
    • Thomas, T.1    Thomas, T.J.2
  • 30
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 31
    • 0033628454 scopus 로고    scopus 로고
    • Effects of genistein and structurally related phytoestrogens on cell cycle kinetics and apoptosis in MDA-MB-468 human breast cancer cells
    • Balabhadrapathruni S, Thomas TJ, Yurkow EJ, Amenta PS and Thomas T: Effects of genistein and structurally related phytoestrogens on cell cycle kinetics and apoptosis in MDA-MB-468 human breast cancer cells. Oncol Rep 7: 3-12, 2000.
    • (2000) Oncol Rep , vol.7 , pp. 3-12
    • Balabhadrapathruni, S.1    Thomas, T.J.2    Yurkow, E.J.3    Amenta, P.S.4    Thomas, T.5
  • 32
    • 0141864377 scopus 로고    scopus 로고
    • Apoptosis, chemoresistance, and breast cancer: Insights from the MCF-7 cell model system
    • Simstein R, Burow M, Parker A, Weldon C and Beckman B: Apoptosis, chemoresistance, and breast cancer: insights from the MCF-7 cell model system. Exp Biol Med 228: 995-1003, 2003. (Pubitemid 37222167)
    • (2003) Experimental Biology and Medicine , vol.228 , Issue.9 , pp. 995-1003
    • Simstein, R.1    Burow, M.2    Parker, A.3    Weldon, C.4    Beckman, B.5
  • 33
    • 1842767259 scopus 로고    scopus 로고
    • Mitochondrial regulation of apoptotic cell death
    • Orrenius S: Mitochondrial regulation of apoptotic cell death. Toxicol Lett 149: 19-23, 2004.
    • (2004) Toxicol Lett , vol.149 , pp. 19-23
    • Orrenius, S.1
  • 34
    • 0040298568 scopus 로고    scopus 로고
    • Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
    • DOI 10.1074/jbc.273.16.9357
    • Janicke RU, Sprengart ML, Wati MR and Porter AG: Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J Biol Chem 273: 9357-9360, 1998. (Pubitemid 28183012)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.16 , pp. 9357-9360
    • Janicke, R.U.1    Sprengart, M.L.2    Wati, M.R.3    Porter, A.G.4
  • 35
    • 0029081697 scopus 로고
    • Induction of programmed cell death in human breast cancer cells by an unsymmetrically alkylated polyamine analogue
    • McCloskey DE, Casero RA Jr, Woster PM and Davidson NE: Induction of programmed cell death in human breast cancer cells by an unsymmetrically alkylated polyamine analogue. Cancer Res 55: 3233-3236, 1995.
    • (1995) Cancer Res , vol.55 , pp. 3233-3236
    • McCloskey, D.E.1    Casero Jr., R.A.2    Woster, P.M.3    Davidson, N.E.4
  • 36
    • 0030684153 scopus 로고    scopus 로고
    • Rapid induction of apoptosis by deregulated uptake of polyamine analogues
    • Hu RH and Pegg AE: Rapid induction of apoptosis by deregulated uptake of polyamine analogues. Biochem J 328: 307-316, 1997.
    • (1997) Biochem J , vol.328 , pp. 307-316
    • Hu, R.H.1    Pegg, A.E.2
  • 38
    • 0036186863 scopus 로고    scopus 로고
    • 11- diethylnorspermine
    • DOI 10.1046/j.0014-2956.2001.02744.x
    • Hegardt C, Johannsson OT and Oredsson SM: Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1, N11-diethylnorspermine. Eur J Biochem 269: 1033-1039, 2002. (Pubitemid 34175425)
    • (2002) European Journal of Biochemistry , vol.269 , Issue.3 , pp. 1033-1039
    • Hegardt, C.1    Johannsson, O.T.2    Oredsson, S.M.3
  • 40
    • 0033426829 scopus 로고    scopus 로고
    • The pure antiestrogen ICI 182780 is more effective in the induction of apoptosis and down regulation of BCL-2 than tamoxifen in MCF-7 cells
    • DOI 10.1023/A:1006338123126
    • Diel P, Smolnikar K and Michna H: The pure antiestrogen ICI 182780 is more effective in the induction of apoptosis and down regulation of BCL-2 than tamoxifen in MCF-7 cells. Breast Cancer Res Treat 58: 87-97, 1999. (Pubitemid 30032479)
    • (1999) Breast Cancer Research and Treatment , vol.58 , Issue.2 , pp. 87-97
    • Diel, P.1    Smolnikar, K.2    Michna, H.3
  • 42
    • 0033621962 scopus 로고    scopus 로고
    • 17β-estradiol inhibits apoptosis in MCF-7 cells, inducing bcl-2 expression via two estrogen-responsive elements present in the coding sequence
    • DOI 10.1128/MCB.20.8.2890-2901.2000
    • Perillo BSA, Abbondanza C and Palumbo G: 17β-estradiol inhibits apoptosis in MCF-7 cells, inducing bcl-2 expression via two-estrogen-responsive elements present in the coding sequence. Mol Cell Biol 20: 2890-2901, 2000. (Pubitemid 30183508)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.8 , pp. 2890-2901
    • Perillo, B.1    Sasso, A.2    Abbondanza, C.3    Palumbo, G.4
  • 43
    • 0035418231 scopus 로고    scopus 로고
    • Apoptotic signaling in polyamine analogue-treated SK-MEL-28 human melanoma cells
    • Chen Y, Kramer DL, Diegelman P, Vujcic S and Porter CW: Apoptotic signaling in polyamine analogue-treated SK-MEL-28 human melanoma cells. Cancer Res 61: 6437-6444, 2001. (Pubitemid 32783249)
    • (2001) Cancer Research , vol.61 , Issue.17 , pp. 6437-6444
    • Chen, Y.1    Kramer, D.L.2    Diegelman, P.3    Vujcic, S.4    Porter, C.W.5
  • 44
    • 1942487852 scopus 로고    scopus 로고
    • Membrane binding and transport of N-aminoethyl-1,2-diamino ethane (dien) and N-aminopropyl-1,3-diamino propane (propen) by rat liver mitochondria and their effects on membrane permeability transition
    • DOI 10.1080/09687680310001654916
    • Dalla Via L, Salvi M, Di Noto V, Stefanelli C and Toninello A: Membrane binding and transport of N-aminoethyl-1,2-diamino ethane (dien) and N-aminopropyl-1,3-diamino propane (propen) by rat liver mitochondria and their effects on membrane permeability transition. Mol Membr Biol 21: 109-118, 2004. (Pubitemid 38524369)
    • (2004) Molecular Membrane Biology , vol.21 , Issue.2 , pp. 109-118
    • Dalla, V.L.1    Salvi, M.2    Di, N.V.3    Stefanelli, C.4    Toninello, A.5
  • 45
    • 0242656497 scopus 로고    scopus 로고
    • Death receptor-induced cell killing
    • Thorburn A: Death receptor-induced cell killing. Cell Signal 16: 139-144, 2004.
    • (2004) Cell Signal , vol.16 , pp. 139-144
    • Thorburn, A.1
  • 48
    • 0008104328 scopus 로고    scopus 로고
    • Unsymmetrically substituted polyamine analogue induces caspase- independent programmed cell death in Bcl-2-overexpressing cells
    • Ha HC, Woster PM and Casero RA Jr. Unsymmetrically substituted polyamine analogue induces caspase-independent programmed cell death in Bcl-2-overexpressing cells. Cancer Res 58: 2711-2714, 1998. (Pubitemid 28311895)
    • (1998) Cancer Research , vol.58 , Issue.13 , pp. 2711-2714
    • Ha, H.C.1    Woster, P.M.2    Casero Jr., R.A.3
  • 49
    • 0036682376 scopus 로고    scopus 로고
    • Meta-analysis of microarrays: Interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer
    • Rhodes DR, Barrette TR, Rubin MA, Ghosh D and Chinnaiyan AM: Meta-analysis of microarrays: interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer. Cancer Res 62: 4427-4433, 2002. (Pubitemid 34827303)
    • (2002) Cancer Research , vol.62 , Issue.15 , pp. 4427-4433
    • Rhodes, D.R.1    Barrette, T.R.2    Rubin, M.A.3    Ghosh, D.4    Chinnaiyan, A.M.5


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