메뉴 건너뛰기




Volumn 58, Issue 2, 1999, Pages 87-97

The pure antiestrogen ICI 182780 is more effective in the induction of apoptosis and down regulation of BCL-2 than tamoxifen in MCF-7 cells

Author keywords

Antiestrogens; Apoptosis; BCL 2; Breast cancer; MCF 7; Tamoxifen; ZM 182780

Indexed keywords

ANTIESTROGEN; ESTROGEN; FULVESTRANT; PROTEIN BCL 2; TAMOXIFEN;

EID: 0033426829     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006338123126     Document Type: Article
Times cited : (72)

References (36)
  • 1
    • 0021618186 scopus 로고
    • The pharmacology and clinical uses of tamoxifen
    • 1. Furr BJ, Jordan VC: The pharmacology and clinical uses of tamoxifen. Pharmacol Ther 25: 127-205, 1984
    • (1984) Pharmacol Ther , vol.25 , pp. 127-205
    • Furr, B.J.1    Jordan, V.C.2
  • 3
    • 0027361914 scopus 로고
    • Molecular mechanisms of resistance to tamoxifen therapy in breast cancer
    • 3. Morrow M, Jordan VC: Molecular mechanisms of resistance to tamoxifen therapy in breast cancer. Arch Surg 128: 1187-1191, 1993
    • (1993) Arch Surg , vol.128 , pp. 1187-1191
    • Morrow, M.1    Jordan, V.C.2
  • 4
    • 0029144331 scopus 로고
    • Possible mechanisms in the emergence of tamoxifenresistant breast cancer
    • 4. Tonetti DA, Jordan VC: Possible mechanisms in the emergence of tamoxifenresistant breast cancer. Anticancer Drugs 6: 498-507, 1995
    • (1995) Anticancer Drugs , vol.6 , pp. 498-507
    • Tonetti, D.A.1    Jordan, V.C.2
  • 5
    • 0027942428 scopus 로고
    • Should clinicians be concerned about the carcinogenic potential of tamoxifen?
    • 5. Jordan VC, Morrow M: Should clinicians be concerned about the carcinogenic potential of tamoxifen? Eur J Cancer 30A: 1714-1721, 1994
    • (1994) Eur J Cancer , vol.30 A , pp. 1714-1721
    • Jordan, V.C.1    Morrow, M.2
  • 6
    • 0010169673 scopus 로고    scopus 로고
    • A realistic clinical perspective of tamoxifen and endometrial carcinogenesis
    • 6. Assikis VJ, Neven P, Jordan VC, Vergote I: A realistic clinical perspective of tamoxifen and endometrial carcinogenesis. Eur J Cancer 32A: 1464-1476, 1996
    • (1996) Eur J Cancer , vol.32 A , pp. 1464-1476
    • Assikis, V.J.1    Neven, P.2    Jordan, V.C.3    Vergote, I.4
  • 7
    • 0000396336 scopus 로고    scopus 로고
    • Should adjuvant tamoxifen therapy be stopped at 5 years?
    • 7. Bilimoria MM, Assikis VJ, Jordan VC: Should adjuvant tamoxifen therapy be stopped at 5 Years? Cancer J Sci Am 2: 140-150, 1996
    • (1996) Cancer J Sci Am , vol.2 , pp. 140-150
    • Bilimoria, M.M.1    Assikis, V.J.2    Jordan, V.C.3
  • 8
    • 0001559063 scopus 로고
    • A new approach to breast cancer therapy - Total estrogen ablation with pure antiestrogen
    • Jordan VC (ed) Madison W, University of Wisconsin
    • 8. Wakeling AE: A new approach to breast cancer therapy - total estrogen ablation with pure antiestrogen. In: Jordan VC (ed) Long-Term Tamoxifen Treatment for Breast Cancer. Madison W, University of Wisconsin, 1994, pp 219-234
    • (1994) Long-term Tamoxifen Treatment for Breast Cancer , pp. 219-234
    • Wakeling, A.E.1
  • 10
    • 0031026744 scopus 로고    scopus 로고
    • Clinical potential of new antiestrogens
    • 10. Gradishar WJ, Jordan VC: Clinical potential of new antiestrogens. J Clin Oncol 15: 840-852, 1997
    • (1997) J Clin Oncol , vol.15 , pp. 840-852
    • Gradishar, W.J.1    Jordan, V.C.2
  • 11
    • 0026395885 scopus 로고
    • A potent specific pure antiestrogen with clinical potential
    • 11. Wakeling AE, Dukes M, Bowler J: A potent specific pure antiestrogen with clinical potential. Cancer Res 51: 3867-3873, 1991
    • (1991) Cancer Res , vol.51 , pp. 3867-3873
    • Wakeling, A.E.1    Dukes, M.2    Bowler, J.3
  • 12
    • 0029048177 scopus 로고
    • MCF-7 human mammary adenocarcinoma cell death in vitro in response to hormone-withdrawal and DNA damage
    • 12. Wilson JW, Wakeling AE, Morris ID, Hickman JA, Dive C: MCF-7 human mammary adenocarcinoma cell death in vitro in response to hormone-withdrawal and DNA damage. Int J Cancer 61: 502-508, 1995
    • (1995) Int J Cancer , vol.61 , pp. 502-508
    • Wilson, J.W.1    Wakeling, A.E.2    Morris, I.D.3    Hickman, J.A.4    Dive, C.5
  • 13
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • 13. Kerr JF, Wyllic AH, Currie AR: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26: 239-257, 1972
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllic, A.H.2    Currie, A.R.3
  • 14
    • 0025204548 scopus 로고
    • BCL-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • 14. Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ: BCL-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348: 334-336, 1990
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 15
    • 0026454763 scopus 로고
    • Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene
    • 15. Garcia I, Martinou I, Tsujimoto Y, Martinou JC: Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science 258: 302-304, 1992
    • (1992) Science , vol.258 , pp. 302-304
    • Garcia, I.1    Martinou, I.2    Tsujimoto, Y.3    Martinou, J.C.4
  • 17
    • 0028929726 scopus 로고
    • Multiple expression patterns of biopathological markers in primary invasive breast carcinoma: A useful tool for elucidating its biological behavior
    • 17. Ceccarelli C, Santini D, Chieco P, Taffurelli M, Marrano D, Mancini AM: Multiple expression patterns of biopathological markers in primary invasive breast carcinoma: a useful tool for elucidating its biological behavior. Ann Oncol 6: 275-282, 1995
    • (1995) Ann Oncol , vol.6 , pp. 275-282
    • Ceccarelli, C.1    Santini, D.2    Chieco, P.3    Taffurelli, M.4    Marrano, D.5    Mancini, A.M.6
  • 18
    • 0029007175 scopus 로고
    • Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7
    • 18. Wang TT, Phang JM: Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7. Cancer Res 55: 2487-2489, 1995
    • (1995) Cancer Res , vol.55 , pp. 2487-2489
    • Wang, T.T.1    Phang, J.M.2
  • 19
    • 0024822416 scopus 로고
    • Antitumor activity of the antiprogestins ZK 98.299 and RU 38.486 in hormone dependent rat and mouse mammary tumors: Mechanistic studies
    • 19. Michna H, Schneider MR, Nishino Y, El Etreby MF: Antitumor activity of the antiprogestins ZK 98.299 and RU 38.486 in hormone dependent rat and mouse mammary tumors: mechanistic studies. Breast Cancer Res Treat 14: 275-288, 1989
    • (1989) Breast Cancer Res Treat , vol.14 , pp. 275-288
    • Michna, H.1    Schneider, M.R.2    Nishino, Y.3    El Etreby, M.F.4
  • 21
    • 0025184879 scopus 로고
    • Use of the polymerase chain reaction in the quantitation of mdr-1 gene expression
    • 21. Murphy I.D, Herzog CE, Rudick JB, Fojo AT, Bates SE: Use of the polymerase chain reaction in the quantitation of mdr-1 gene expression. Biochemistry 29: 10351-10356, 1990
    • (1990) Biochemistry , vol.29 , pp. 10351-10356
    • Murphy, I.D.1    Herzog, C.E.2    Rudick, J.B.3    Fojo, A.T.4    Bates, S.E.5
  • 22
    • 0029896182 scopus 로고    scopus 로고
    • Sexual dimorphism of steroid hormone receptor messenger ribonucleic acid expression and hormonal regulation in rat vascular tissue
    • 22. Knauthe R, Diel P, Hegele-Hartung C, Engelhaupt A, Fritzemeier KH: Sexual dimorphism of steroid hormone receptor messenger ribonucleic acid expression and hormonal regulation in rat vascular tissue. Endocrinology 137: 3220-3227, 1996
    • (1996) Endocrinology , vol.137 , pp. 3220-3227
    • Knauthe, R.1    Diel, P.2    Hegele-Hartung, C.3    Engelhaupt, A.4    Fritzemeier, K.H.5
  • 23
    • 0027301384 scopus 로고
    • Apoptosis in toremifene-induced growth inhibition of human breast cancer cells in vivo and in vitro
    • 23. Warri AM, Huovinen RL, Laine AM, Martikainen PM, Harkonen PL: Apoptosis in toremifene-induced growth inhibition of human breast cancer cells in vivo and in vitro, J Natl Cancer Inst 85: 1412-1418, 1993
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1412-1418
    • Warri, A.M.1    Huovinen, R.L.2    Laine, A.M.3    Martikainen, P.M.4    Harkonen, P.L.5
  • 24
    • 0026088670 scopus 로고
    • Programmed cell death during regression of the MCF-7 human breast cancer following estrogen ablation
    • 24. Kyprianou N, English HF, Davidson NE, Isaacs JT: Programmed cell death during regression of the MCF-7 human breast cancer following estrogen ablation. Cancer Res 51: 162-166, 1991
    • (1991) Cancer Res , vol.51 , pp. 162-166
    • Kyprianou, N.1    English, H.F.2    Davidson, N.E.3    Isaacs, J.T.4
  • 25
    • 0029741890 scopus 로고    scopus 로고
    • Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: The role of autophagy
    • 25. Bursch W, Ellinger A, Kienzl H, Torok L, Pandey S, Sikorska M, Walker R, Hermann RS: Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy. Carcinogenesis 17: 1595-1607, 1996
    • (1996) Carcinogenesis , vol.17 , pp. 1595-1607
    • Bursch, W.1    Ellinger, A.2    Kienzl, H.3    Torok, L.4    Pandey, S.5    Sikorska, M.6    Walker, R.7    Hermann, R.S.8
  • 26
    • 0029303048 scopus 로고
    • Effects of tamoxifen on growth and apoptosis of estrogen-dependent and -independent human breast cancer cells
    • 26. Perry RR, Kang Y, Greaves B: Effects of tamoxifen on growth and apoptosis of estrogen-dependent and -independent human breast cancer cells. Ann Surg Oncol 2: 238-245, 1995
    • (1995) Ann Surg Oncol , vol.2 , pp. 238-245
    • Perry, R.R.1    Kang, Y.2    Greaves, B.3
  • 28
    • 0027166048 scopus 로고
    • BCL-2 heterodimerizes in vivo with a conserved homolog, bax, that accelerates programmed cell death
    • 28. Oltvai ZN, Milliman CL, Korsmeyer SJ: BCL-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74: 609-619, 1993
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 29
    • 0028944271 scopus 로고
    • Expression of the bcl-2 gene family in normal and malignant breast tissue: Low bax-alpha expression in tumor cells correlates with resistance towards apoptosis
    • 29. Bargou RC, Daniel PT, Mapara MY, Bommert K, Wagener C, Kallinich B, Royer HD, Dörken B: Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis. Int J Cancer 60: 854-859, 1995
    • (1995) Int J Cancer , vol.60 , pp. 854-859
    • Bargou, R.C.1    Daniel, P.T.2    Mapara, M.Y.3    Bommert, K.4    Wagener, C.5    Kallinich, B.6    Royer, H.D.7    Dörken, B.8
  • 30
    • 0028115802 scopus 로고
    • Bcl-2 in normal human breast and carcinoma, association with oestrogen receptor-positive, epidermal growth factor receptor-negative tumors and in situ cancer
    • 30. Leek RD, Kaklamanis L, Pezzella F, Gatter KC, Harris AL: bcl-2 in normal human breast and carcinoma, association with oestrogen receptor-positive, epidermal growth factor receptor-negative tumors and in situ cancer. Br J Cancer 69: 135-139, 1994
    • (1994) Br J Cancer , vol.69 , pp. 135-139
    • Leek, R.D.1    Kaklamanis, L.2    Pezzella, F.3    Gatter, K.C.4    Harris, A.L.5
  • 31
    • 1842413054 scopus 로고    scopus 로고
    • Tumor growth inhibition, apoptosis, and BCL-2 down-regulation of MCF-7ras tumors by sodium phenylacetate and tamoxifen combination
    • 31. Adam L, Crepin M, Israel L: Tumor growth inhibition, apoptosis, and BCL-2 down-regulation of MCF-7ras tumors by sodium phenylacetate and tamoxifen combination. Cancer Res 57: 1023-1029, 1997
    • (1997) Cancer Res , vol.57 , pp. 1023-1029
    • Adam, L.1    Crepin, M.2    Israel, L.3
  • 33
    • 0026040217 scopus 로고
    • The mechanism of ICI 164,384 antiestrogenicity involves rapid loss of estrogen receptor in uterine tissue
    • 33. Gibson MK, Nemmers LA, Beckman WC Jr, Davis VL, Curtis SW, Korach KS: The mechanism of ICI 164,384 antiestrogenicity involves rapid loss of estrogen receptor in uterine tissue. Endocrinology 129: 2000-2010, 1991
    • (1991) Endocrinology , vol.129 , pp. 2000-2010
    • Gibson, M.K.1    Nemmers, L.A.2    Beckman W.C., Jr.3    Davis, V.L.4    Curtis, S.W.5    Korach, K.S.6
  • 34
    • 0027768899 scopus 로고
    • The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling
    • 34. Dauvois S, White R, Parker MG: The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling. J Cell Sci 106: 1377-1388, 1993
    • (1993) J Cell Sci , vol.106 , pp. 1377-1388
    • Dauvois, S.1    White, R.2    Parker, M.G.3
  • 35
    • 0018175970 scopus 로고
    • Estrogen control of progesterone receptor in human breast cancer: Role of estradiol and antiestrogen
    • 35. Horwitz KB, Koseki Y, McGuire WL: Estrogen control of progesterone receptor in human breast cancer: role of estradiol and antiestrogen. Endocrinology 103: 1742-1751, 1978
    • (1978) Endocrinology , vol.103 , pp. 1742-1751
    • Horwitz, K.B.1    Koseki, Y.2    McGuire, W.L.3
  • 36
    • 0025892428 scopus 로고
    • Characterization of the hormone responsive element involved in the regulation of the progesterone receptor gene
    • 36. Savouret JF, Bailly A, Misrahi M, Rauch C, Redeuilh G, Chauchereau A, Milgrom E: Characterization of the hormone responsive element involved in the regulation of the progesterone receptor gene. EMBO J 10: 1875-1883, 1991
    • (1991) Embo J , vol.10 , pp. 1875-1883
    • Savouret, J.F.1    Bailly, A.2    Misrahi, M.3    Rauch, C.4    Redeuilh, G.5    Chauchereau, A.6    Milgrom, E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.