Leptin receptors are expressed in coronary arteries, and hyperleptinemia causes significant coronary endothelial dysfunction

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 289, Issue 1 58-1, 2005, Pages

  Knudson, Jarrod D ^a   Dincer, Ü Deniz ^a   Zhang, Cuihua ^a   Swafford Jr , Albert N ^a   Koshida, Ryoji ^a   Picchi, Andrea ^a   Focardi, Marta ^a   Dick, Gregory M ^a   Tune, Johnathan D ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Coronary circulation; Endothelium; Metabolic syndrome; Microcirculation; Obesity

Indexed keywords

ACETYLCHOLINE; LEPTIN; LEPTIN RECEPTOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY BLOOD FLOW; DOG; ENDOTHELIUM CELL; GENE EXPRESSION; HEART MUSCLE OXYGEN CONSUMPTION; HUMAN; HUMAN CELL; HYPERLEPTINEMIA; IMMUNOCYTOCHEMISTRY; ISCHEMIC HEART DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK FACTOR; VASODILATATION;

ANIMALS; ARTERIOLES; CELLS, CULTURED; CORONARY CIRCULATION; CORONARY VESSELS; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; HUMANS; HYPERLIPIDEMIAS; LEPTIN; NITRIC OXIDE; OBESITY; RATS; RATS, ZUCKER; RECEPTORS, CELL SURFACE; VASODILATION;

EID: 21644438084     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.01159.2004     Document Type: Article

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