메뉴 건너뛰기




Volumn 54, Issue 7, 2005, Pages 1958-1967

Impact of the liver-specific expression of SHIP2 (SH2-containing inositol 5′-phosphatase 2) on insulin signaling and glucose metabolism in mice

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; GLUCOSE; GLUCOSE 6 PHOSPHATASE; INSULIN RECEPTOR SUBSTRATE 1; LIVER ENZYME; MESSENGER RNA; PHOSPHATIDYLINOSITOL; PROTEIN SH2; SH2 CONTAINING INOSITOL 5' PHOSPHATASE 2; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; UNCLASSIFIED DRUG;

EID: 21344475048     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.54.7.1958     Document Type: Article
Times cited : (58)

References (50)
  • 1
    • 0036434431 scopus 로고    scopus 로고
    • Insulin regulation of glucose uptake: A complex interplay of intracellular signalling pathways
    • Khan AH, Pessin JE: Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways. Diabetologia 45:1475-1483, 2002
    • (2002) Diabetologia , vol.45 , pp. 1475-1483
    • Khan, A.H.1    Pessin, J.E.2
  • 2
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signalling and the regulation of glucose and lipid metabolism
    • Saltiel AR, Kahn CR: Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414:799-806, 2001
    • (2001) Nature , vol.414 , pp. 799-806
    • Saltiel, A.R.1    Kahn, C.R.2
  • 3
    • 0036710280 scopus 로고    scopus 로고
    • IRS proteins and the common path to diabetes
    • White MF: IRS proteins and the common path to diabetes. Am J Physiol Endocrinol Metab 283:E413-E422, 2002
    • (2002) Am J Physiol Endocrinol Metab , vol.283
    • White, M.F.1
  • 4
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley LC: The phosphoinositide 3-kinase pathway. Science 296:1655-1657, 2002
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 5
    • 0032143284 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase: The key switch mechanism in insulin signalling
    • Shepherd PR, Withers DJ, Siddle K: Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling. Biochem J 333:471-490, 1998
    • (1998) Biochem J , vol.333 , pp. 471-490
    • Shepherd, P.R.1    Withers, D.J.2    Siddle, K.3
  • 6
    • 0036143774 scopus 로고    scopus 로고
    • Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival
    • Ueki K, Fruman DA, Brachmann SM, Tseng Y-H, Cantley LC, Kahn CR: Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival. Mol Cell Biol 22:965-977, 2002
    • (2002) Mol Cell Biol , vol.22 , pp. 965-977
    • Ueki, K.1    Fruman, D.A.2    Brachmann, S.M.3    Tseng, Y.-H.4    Cantley, L.C.5    Kahn, C.R.6
  • 8
    • 3543017307 scopus 로고    scopus 로고
    • Intracellular delivery of phosphatidylinositol (3,4,5)-trisphosphate causes incorporation of glucose transporter 4 into the plasma membrane of muscle and fat cells without increasing glucose uptake
    • Sweeney G, Garg RR, Ceddia RB, Li D, Ishiki M, Somwar R, Foster LJ, Neilsen PO, Prestwich GD, Rudich A, Klip A: Intracellular delivery of phosphatidylinositol (3,4,5)-trisphosphate causes incorporation of glucose transporter 4 into the plasma membrane of muscle and fat cells without increasing glucose uptake. J Biol Chem 279:32233-32242, 2004
    • (2004) J Biol Chem , vol.279 , pp. 32233-32242
    • Sweeney, G.1    Garg, R.R.2    Ceddia, R.B.3    Li, D.4    Ishiki, M.5    Somwar, R.6    Foster, L.J.7    Neilsen, P.O.8    Prestwich, G.D.9    Rudich, A.10    Klip, A.11
  • 9
    • 0242468741 scopus 로고    scopus 로고
    • Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change
    • Milburn CC, Deak M, Kelly SM, Price NC, Alessi DR, Van Aalten DM: Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change. Biochem J 375:531-538, 2003
    • (2003) Biochem J , vol.375 , pp. 531-538
    • Milburn, C.C.1    Deak, M.2    Kelly, S.M.3    Price, N.C.4    Alessi, D.R.5    Van Aalten, D.M.6
  • 10
    • 1542328927 scopus 로고    scopus 로고
    • Structure, regulation and function of PKB/AKT: A major therapeutic target
    • Hanada M, Feng J, Hemmings BA: Structure, regulation and function of PKB/AKT: a major therapeutic target. Biochim Biophys Acta 1697:3-16, 2004
    • (2004) Biochim Biophys Acta , vol.1697 , pp. 3-16
    • Hanada, M.1    Feng, J.2    Hemmings, B.A.3
  • 11
    • 0031590449 scopus 로고    scopus 로고
    • Identification of a second SH2-domain-containing protein closely related to the phosphatidylinositol polyphosphate 5-phosphatase SHIP
    • Pesesse X, Deleu S, De Smedt F, Drayer L, Erneux C: Identification of a second SH2-domain-containing protein closely related to the phosphatidylinositol polyphosphate 5-phosphatase SHIP. Biochem Biophys Res Commun 239:697-700, 1997
    • (1997) Biochem Biophys Res Commun , vol.239 , pp. 697-700
    • Pesesse, X.1    Deleu, S.2    De Smedt, F.3    Drayer, L.4    Erneux, C.5
  • 16
    • 0032561507 scopus 로고    scopus 로고
    • The SH2 domain containing inositol 5-phosphatase SHIP2 displays phosphatidylinositol 3,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate 5-phosphatase activity
    • Pesesse X, Moreau C, Drayer AL, Woscholski R, Parker P, Erneux C: The SH2 domain containing inositol 5-phosphatase SHIP2 displays phosphatidylinositol 3,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate 5-phosphatase activity. FEBS Lett 437:301-303, 1998
    • (1998) FEBS Lett , vol.437 , pp. 301-303
    • Pesesse, X.1    Moreau, C.2    Drayer, A.L.3    Woscholski, R.4    Parker, P.5    Erneux, C.6
  • 17
    • 0037702455 scopus 로고    scopus 로고
    • The termination of PI3K signalling by SHIP1 and SHIP2 inositol 5-phosphatases
    • Backers K, Blero D, Paternotte N, Zhang J, Erneux C: The termination of PI3K signalling by SHIP1 and SHIP2 inositol 5-phosphatases. Adv Enzyme Regul 43:15-28, 2003
    • (2003) Adv Enzyme Regul , vol.43 , pp. 15-28
    • Backers, K.1    Blero, D.2    Paternotte, N.3    Zhang, J.4    Erneux, C.5
  • 18
    • 0035135318 scopus 로고    scopus 로고
    • Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5′-phosphatase catalytic activity
    • Wada T, Sasaoka T, Funaki M, Hori H, Murakami S, Ishiki M, Haruta T, Asano T, Ogawa W, Ishihara H, Kobayashi M: Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5′-phosphatase catalytic activity. Mol Cell Biol 21:163-1646, 2001
    • (2001) Mol Cell Biol , vol.21 , pp. 163-1646
    • Wada, T.1    Sasaoka, T.2    Funaki, M.3    Hori, H.4    Murakami, S.5    Ishiki, M.6    Haruta, T.7    Asano, T.8    Ogawa, W.9    Ishihara, H.10    Kobayashi, M.11
  • 19
    • 0034775501 scopus 로고    scopus 로고
    • SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes
    • Sasaoka T, Hori H, Wada T, Ishiki M, Haruta T, Ishihara H, Kobayashi M: SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes. Diabetologia 44:1258-1267, 2001
    • (2001) Diabetologia , vol.44 , pp. 1258-1267
    • Sasaoka, T.1    Hori, H.2    Wada, T.3    Ishiki, M.4    Haruta, T.5    Ishihara, H.6    Kobayashi, M.7
  • 20
    • 2442553111 scopus 로고    scopus 로고
    • SH2-containing inositol phosphatase 2 predominantly regulates Akt2, and not Akt1, phosphorylation at the plasma membrane in response to insulin in 3T3-L1 adipocytes
    • Sasaoka T, Wada T, Fukui K, Murakami S, Ishihara H, Suzuki R, Tobe K, Kadowaki T, Kobayashi M: SH2-containing inositol phosphatase 2 predominantly regulates Akt2, and not Akt1, phosphorylation at the plasma membrane in response to insulin in 3T3-L1 adipocytes. J Biol Chem 279:14835-14843, 2004
    • (2004) J Biol Chem , vol.279 , pp. 14835-14843
    • Sasaoka, T.1    Wada, T.2    Fukui, K.3    Murakami, S.4    Ishihara, H.5    Suzuki, R.6    Tobe, K.7    Kadowaki, T.8    Kobayashi, M.9
  • 21
    • 0036329397 scopus 로고    scopus 로고
    • Association of SH2-containing inositol phosphatase 2 with the insulin resistance of diabetic db/db mice
    • Hori H, Sasaoka T, Ishihara H, Wada T, Murakami S, Ishiki M, Kobayashi M: Association of SH2-containing inositol phosphatase 2 with the insulin resistance of diabetic db/db mice. Diabetes 51:2387-2394, 2002
    • (2002) Diabetes , vol.51 , pp. 2387-2394
    • Hori, H.1    Sasaoka, T.2    Ishihara, H.3    Wada, T.4    Murakami, S.5    Ishiki, M.6    Kobayashi, M.7
  • 22
    • 3042687456 scopus 로고    scopus 로고
    • Impact of Src homology 2-containing inositol 5′-phosphatase 2 on the regulation of insulin signaling leading to protein synthesis in 3T3-L1 adipocytes cultured with excess amino acids
    • Murakami S, Sasaoka T, Wada T, Fukui K, Nagira K, Ishihara H, Usui I, Kobayashi M: Impact of Src homology 2-containing inositol 5′-phosphatase 2 on the regulation of insulin signaling leading to protein synthesis in 3T3-L1 adipocytes cultured with excess amino acids. Endocrinology 145:3215-3223, 2004
    • (2004) Endocrinology , vol.145 , pp. 3215-3223
    • Murakami, S.1    Sasaoka, T.2    Wada, T.3    Fukui, K.4    Nagira, K.5    Ishihara, H.6    Usui, I.7    Kobayashi, M.8
  • 23
  • 24
    • 0034687208 scopus 로고    scopus 로고
    • Diabetes: The importance of the liver
    • Rutter GA: Diabetes: the importance of the liver. Curr Biol 10:R736-R738, 2000
    • (2000) Curr Biol , vol.10
    • Rutter, G.A.1
  • 27
    • 0031982799 scopus 로고    scopus 로고
    • Liver microsomal glucose-6-phosphatase is competitively inhibited by the lipid products of phosphatidylinositol 3-kinase
    • Mithieux G, Daniele N, Payrastre B, Zitoun C: Liver microsomal glucose-6-phosphatase is competitively inhibited by the lipid products of phosphatidylinositol 3-kinase. J Biol Chem 273:17-19, 1998
    • (1998) J Biol Chem , vol.273 , pp. 17-19
    • Mithieux, G.1    Daniele, N.2    Payrastre, B.3    Zitoun, C.4
  • 29
    • 0141839103 scopus 로고    scopus 로고
    • Novel concepts in insulin regulation of hepatic gluconeogenesis
    • Barthel A, Schmoll D: Novel concepts in insulin regulation of hepatic gluconeogenesis. Am J Physiol Endocrinol Metab 285:E685-E692, 2003
    • (2003) Am J Physiol Endocrinol Metab , vol.285
    • Barthel, A.1    Schmoll, D.2
  • 30
    • 0036260017 scopus 로고    scopus 로고
    • Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element-binding protein 1c and glucokinase genes in rat hepatocytes
    • Matsumoto M, Ogawa W, Teshigawara K, Inoue H, Miyake K, Sakaue H, Kasuga M: Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element-binding protein 1c and glucokinase genes in rat hepatocytes. Diabetes 51:1672-1680, 2002
    • (2002) Diabetes , vol.51 , pp. 1672-1680
    • Matsumoto, M.1    Ogawa, W.2    Teshigawara, K.3    Inoue, H.4    Miyake, K.5    Sakaue, H.6    Kasuga, M.7
  • 31
    • 0027247998 scopus 로고
    • The regulation of gene expression by insulin is differentially impaired in the liver of the genetically obese-hyperglycemic Wistar fatty rat
    • Noguchi T, Matsuda T, Tomari Y, Yamada K, Imai E, Wang Z, Ikeda H, Tanaka T: The regulation of gene expression by insulin is differentially impaired in the liver of the genetically obese-hyperglycemic Wistar fatty rat. FEBS Lett 328:145-148, 1993
    • (1993) FEBS Lett , vol.328 , pp. 145-148
    • Noguchi, T.1    Matsuda, T.2    Tomari, Y.3    Yamada, K.4    Imai, E.5    Wang, Z.6    Ikeda, H.7    Tanaka, T.8
  • 32
    • 0029797604 scopus 로고    scopus 로고
    • Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
    • Shimano H, Horton JD, Hammer RE, Shimomura I, Brown MS, Goldstein JL: Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J Clin Invest 98:1575-1584, 1996
    • (1996) J Clin Invest , vol.98 , pp. 1575-1584
    • Shimano, H.1    Horton, J.D.2    Hammer, R.E.3    Shimomura, I.4    Brown, M.S.5    Goldstein, J.L.6
  • 35
    • 0036853886 scopus 로고    scopus 로고
    • Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver
    • Miyake K, Ogawa W, Matsumoto M, Nakamura T, Sakaue H, Kasuga M: Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver. J Clin Invest 110:1483-1491, 2002
    • (2002) J Clin Invest , vol.110 , pp. 1483-1491
    • Miyake, K.1    Ogawa, W.2    Matsumoto, M.3    Nakamura, T.4    Sakaue, H.5    Kasuga, M.6
  • 39
    • 0033956846 scopus 로고    scopus 로고
    • The db/db mouse, a model for diabetic dyslipidemia: Molecular characterization and effects of Western diet feeding
    • Kobayashi K, Forte TM, Taniguchi S, Ishida BY, Oka K, Chan L: The db/db mouse, a model for diabetic dyslipidemia: molecular characterization and effects of Western diet feeding. Metabolism 49:22-31, 2000
    • (2000) Metabolism , vol.49 , pp. 22-31
    • Kobayashi, K.1    Forte, T.M.2    Taniguchi, S.3    Ishida, B.Y.4    Oka, K.5    Chan, L.6
  • 42
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • Maehama T, Dixon JE: The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 273:13375-13378, 1998
    • (1998) J Biol Chem , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 45
    • 0035787576 scopus 로고    scopus 로고
    • Cell-specific roles of glucokinase in glucose homeostasis
    • Postic C, Shiota M, Magnuson MA: Cell-specific roles of glucokinase in glucose homeostasis. Recent Prog Horm Res 56:195-217, 2001
    • (2001) Recent Prog Horm Res , vol.56 , pp. 195-217
    • Postic, C.1    Shiota, M.2    Magnuson, M.A.3
  • 46
    • 0141704191 scopus 로고    scopus 로고
    • Overexpression of sterol regulatory element-binding protein-la in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver
    • Horton JD, Shimomura I, Ikemoto S, Bashmakov Y, Hammer RE: Overexpression of sterol regulatory element-binding protein-la in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver. J Biol Chem 278:36652-36660, 2003
    • (2003) J Biol Chem , vol.278 , pp. 36652-36660
    • Horton, J.D.1    Shimomura, I.2    Ikemoto, S.3    Bashmakov, Y.4    Hammer, R.E.5
  • 47
    • 4644311421 scopus 로고    scopus 로고
    • Hepatic insulin resistance precedes the development of diabetes in a model of intrauterine growth retardation
    • Vuguin P, Raab E, Liu B, Barzilai N, Simmons R: Hepatic insulin resistance precedes the development of diabetes in a model of intrauterine growth retardation. Diabetes 53:2617-2622, 2004
    • (2004) Diabetes , vol.53 , pp. 2617-2622
    • Vuguin, P.1    Raab, E.2    Liu, B.3    Barzilai, N.4    Simmons, R.5
  • 48
    • 0033636780 scopus 로고    scopus 로고
    • Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice
    • Shimomura I, Matsuda M, Hammer RE, Bashmakov Y, Brown MS, Goldstein JL: Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. Mol Cell 6:77-86, 2000
    • (2000) Mol Cell , vol.6 , pp. 77-86
    • Shimomura, I.1    Matsuda, M.2    Hammer, R.E.3    Bashmakov, Y.4    Brown, M.S.5    Goldstein, J.L.6
  • 49
    • 0030856736 scopus 로고    scopus 로고
    • Metabolic impact of adenovirus-mediated overexpression of the glucose-6-phosphatase catalytic subunit in hepatocytes
    • Seoane J, Trinh K, O'Doherty RM, Gómez-Foix AM, Lange AJ, Newgard CB, Guinovart JJ: Metabolic impact of adenovirus-mediated overexpression of the glucose-6-phosphatase catalytic subunit in hepatocytes. J Biol Chem 272:26972-26977, 1997
    • (1997) J Biol Chem , vol.272 , pp. 26972-26977
    • Seoane, J.1    Trinh, K.2    O'Doherty, R.M.3    Gómez-Foix, A.M.4    Lange, A.J.5    Newgard, C.B.6    Guinovart, J.J.7
  • 50
    • 0037189517 scopus 로고    scopus 로고
    • Phosphoenolpyruvate carboxykinase overexpression selectively attenuates insulin signaling and hepatic insulin sensitivity in transgenic mice
    • Sun Y, Liu S, Ferguson S, Wang L, Klepcyk P, Yun JS, Friedman JE: Phosphoenolpyruvate carboxykinase overexpression selectively attenuates insulin signaling and hepatic insulin sensitivity in transgenic mice. J Biol Chem 277:23301-23307, 2002
    • (2002) J Biol Chem , vol.277 , pp. 23301-23307
    • Sun, Y.1    Liu, S.2    Ferguson, S.3    Wang, L.4    Klepcyk, P.5    Yun, J.S.6    Friedman, J.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.