Novel interaction of the Hsp90 chaperone machine with Ssl2, an essential DNA helicase in Saccharomyces cerevisiae

Current Genetics

Volumn 47, Issue 6, 2005, Pages 368-380

  Flom, Gary ^a   Weekes, Jared ^a   Johnson, Jill L ^a  

^a UNIVERSITY OF IDAHO   (United States)

Author keywords

Hop; Ssl2 XPB; Sti1; TFIIH; Utp21

Indexed keywords

CHAPERONE; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR; DNA; GENE PRODUCT; HEAT SHOCK PROTEIN 90; HELICASE; PROTEIN SSL2; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ARTICLE; CELL FUNCTION; DNA REPAIR; DNA TRANSCRIPTION; FUNGUS GROWTH; GENE MUTATION; GENETIC CODE; GENETIC SCREENING; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SACCHAROMYCES CEREVISIAE; STRUCTURAL HOMOLOGY;

DNA HELICASES; DNA REPAIR; HSP90 HEAT-SHOCK PROTEINS; MUTATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION, GENETIC;

SACCHAROMYCES CEREVISIAE;

EID: 21344449336     PISSN: 01728083     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00294-005-0580-6     Document Type: Article

References (84)

1. Abbas-Terki T, Briand PA, Donze O, Picard D (2002) The Hsp90 co-chaperones Cdc37 and Sti1 interact physically and genetically. Biol Chem 383:1335-1342 1:CAS:528:DC%2BD38Xpt1ertrg%3D
2. Atencio DP, Yaffe MP (1992) MAS5, a yeast homolog of DnaJ involved in mitochondrial protein import. Mol Cell Biol 12:283-291 1:STN:280:By2C3cjhsl0%3D
3. Bali M, Zhang B, Morano KA, Michels CA (2003) The Hsp90 molecular chaperone complex regulates maltose induction and stability of the Saccharomyces MAL gene transcription activator Mal63p. J Biol Chem 278:47441-47448 1:CAS:528:DC%2BD3sXpt1Cqtrk%3D
4. Bansal PK, Abdulle R, Kitagawa K (2004) Sgt1 associates with Hsp90: An initial step of assembly of the core kinetochore complex. Mol Cell Biol 24:8069-8079 1:CAS:528:DC%2BD2cXnslCrsLY%3D
5. Bender A, Pringle JR (1991) Use of a screen for synthetic lethal and multicopy suppressee mutants to identify two new genes involved in morphogenesis in Saccharomyces cerevisiae. Mol Cell Biol 11:1295-1305 1:CAS:528:DyaK3MXltVOnsb4%3D
6. Bisht KS, et al (2003) Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity. Cancer Res 63:8984-8995 1:CAS:528:DC%2BD3sXhtVSqtbbP
7. Bohen SP, Yamamoto KR (1993) Isolation of Hsp90 mutants by screening for decreased steroid receptor function. Proc Natl Acad Sci USA 90:11424-11428 1:CAS:528:DyaK2cXnsVyitw%3D%3D
8. Borkovich KA, Farrelly FW, Finkelstein DB, Taulien J, Lindquist S (1989) hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures. Mol Cell Biol 9:3919-3930 1:CAS:528:DyaK3cXpt1yksw%3D%3D
9. Brugge J, Yonemoto W, Darrow D (1983) Interaction between the Rous sarcoma virus transforming protein and two cellular phosphoproteins: analysis of the turnover and distribution of this complex. Mol Cell Biol 3:9-19 1:CAS:528:DyaL3sXltVWkuw%3D%3D
10. Camphausen K, Tofilon PJ (2004) Combining radiation and molecular targeting in cancer therapy. Cancer Biol Ther 3:247-250 1:CAS:528:DC%2BD2cXmt1Cmsb8%3D
11. Caplan AJ, Douglas MG (1991) Characterization of YDJ1: A yeast homologue of the bacterial dnaJ protein. J Cell Biol 114:609-621 1:CAS:528:DyaK38Xhs1OmsLs%3D
12. Carr-Schmid A, Pfund C, Craig EA, Kinzy TG (2002) Novel G-protein complex whose requirement is linked to the translational status of the cell. Mol Cell Biol 22:2564-2574 1:CAS:528:DC%2BD38XislWnsLc%3D
13. Chang HC, Nathan DF, Lindquist S (1997) In vivo analysis of the Hsp90 cochaperone Sti1 (p60). Mol Cell Biol 17:318-325 1:CAS:528:DyaK2sXhtlCqtA%3D%3D
14. Chen S, Smith DF (1998) Hop as an adaptor in the heat shock protein 70 (Hsp70) and hsp90 chaperone machinery. J Biol Chem 273:35194-35200 1:CAS:528:DyaK1MXisFagsw%3D%3D
15. Chen S, Prapapanich V, Rimerman RA, Honore B, Smith DF (1996) Interactions of p60, a mediator of progesterone receptor assembly, with heat shock proteins hsp90 and hsp70. Mol Endocrinol 10:682-693 1:CAS:528:DyaK28XjsVSqs7c%3D
16. Dey B, Caplan AJ, Boschelli F (1996) The Ydj1 molecular chaperone facilitates formation of active p60v-src in yeast. Mol Biol Cell 7:91-100 1:CAS:528:DyaK28XnvVyhsA%3D%3D
17. Donze O, Picard D (1999) Hsp90 binds and regulates Gcn2, the ligand-inducible kinase of the alpha subunit of eukaryotic translation initiation factor 2 [corrected]. Mol Cell Biol 19:8422-8432 1:CAS:528:DyaK1MXns1ygtbc%3D
18. Dosil M, Bustelo XR (2004) Functional characterization of Pwp2, a WD family protein essential for the assembly of the 90 S pre-ribosomal particle. J Biol Chem 279:37385-37397 1:CAS:528:DC%2BD2cXntFSguro%3D
19. Dragon F, et al (2002) A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature 417:967-970 1:CAS:528:DC%2BD38XkvVagsLg%3D
20. Duina AA, Marsh JA, Gaber RF (1996) Identification of two CyP-40-like cyclophilins in Saccharomyces cerevisiae, one of which is required for normal growth. Yeast 12:943-952 1:CAS:528:DyaK28XltleqtLk%3D
21. Duina AA, Kalton HM, Gaber RF (1998) Requirement for Hsp90 and a CyP-40-type cyclophilin in negative regulation of the heat shock response. J Biol Chem 273:18974-18978 1:CAS:528:DyaK1cXltFGrt74%3D
22. Fang Y, Fliss AE, Rao J, Caplan AJ (1998) SBA1 encodes a yeast hsp90 cochaperone that is homologous to vertebrate p23 proteins. Mol Cell Biol 18:3727-3734 1:CAS:528:DyaK1cXkt1Squ7o%3D
23. Feaver WJ et al (1993) Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair. Cell 75:1379-1387 1:CAS:528:DyaK2cXntVOqsQ%3D%3D
24. Freeman BC, Yamamoto KR (2002) Disassembly of transcriptional regulatory complexes by molecular chaperones. Science 296:2232-2235 1:CAS:528:DC%2BD38XkvFGht7w%3D
25. Ghaemmaghami S, et al (2003) Global analysis of protein expression in yeast. Nature 425:737-741 1:CAS:528:DC%2BD3sXotV2iu7c%3D
26. Giglia-Mari G, et al (2004) A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A. Nat Genet 36:714-719 1:CAS:528:DC%2BD2cXlt1Crsr8%3D
27. Gulyas KD, Donahue TF (1992) SSL2, a suppressor of a stem-loop mutation in the HIS4 leader encodes the yeast homolog of human ERCC-3. Cell 69:1031-1042 1:CAS:528:DyaK3sXkt1Wlt74%3D
28. Guzder SN, Sung P, Bailly V, Prakash L, Prakash S (1994) RAD25 is a DNA helicase required for DNA repair and RNA polymerase II transcription. Nature 369:578-581 1:CAS:528:DyaK2cXlsFWrt78%3D
29. Hernandez MP, Chadli A, Toft DO (2002) HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor. J Biol Chem 277:11873-11881 1:CAS:528:DC%2BD38XivVeksLc%3D
30. Ho Y, et al (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature 415:180-183 1:CAS:528:DC%2BD38Xms1SnsA%3D%3D
31. Imai J, Yahara I (2000) Role of HSP90 in salt stress tolerance via stabilization and regulation of calcineurin. Mol Cell Biol 20:9262-9270 1:CAS:528:DC%2BD3MXivVamu7Y%3D
32. Imai J, Maruya M, Yashiroda H, Yahara I, Tanaka K (2003) The molecular chaperone Hsp90 plays a role in the assembly and maintenance of the 26S proteasome. EMBO J 22:3557-3567 1:CAS:528:DC%2BD3sXlsl2lurk%3D
33. Isaacs JS, Xu W, Neckers L (2003) Heat shock protein 90 as a molecular target for cancer therapeutics. Cancer Cell 3:213-217 1:CAS:528:DC%2BD3sXislOrtb8%3D
34. Ito H, Fukuda Y, Murata K, Kimura A (1983) Transformation of intact yeast cells treated with alkali cations. J Bacteriol 153:163-168 1:CAS:528:DyaL3sXht1alsLs%3D
35. Itoh H, Ogura M, Komatsuda A, Wakui H, Miura AB, Tashima Y (1999) A novel chaperone-activity-reducing mechanism of the 90-kDa molecular chaperone HSP90. Biochem J 343:697-703 1:CAS:528:DyaK1MXntlymurc%3D
36. Johnson JL, Craig EA (2000) A role for the Hsp40 Ydj1 in repression of basal steroid receptor activity in yeast. Mol Cell Biol 20:3027-3036 1:CAS:528:DC%2BD3cXivFSkt7s%3D
37. Johnson JL, Craig EA (2002) Identifying functional interactions with molecular chaperones. Methods Enzymol 351:442-453 1:CAS:528:DC%2BD38XlsVejs70%3D
38. Kimura Y, Matsumoto S, Yahara I (1994) Temperature-sensitive mutants of hsp82 of the budding yeast Saccharomyces cerevisiae. Mol Gen Genet 242:517-527 1:CAS:528:DyaK2cXkt1ygsrg%3D
39. Kimura Y, Yahara I, Lindquist S (1995) Role of the protein chaperone YDJ1 in establishing Hsp90-mediated signal transduction pathways. Science 268:1362-1365 1:CAS:528:DyaK2MXmtVart7o%3D
40. Lee P, Shabbir A, Cardozo C, Caplan AJ (2004) Sti1 and Cdc37 can stabilize Hsp90 in chaperone complexes with a protein kinase. Mol Biol Cell 15:1785-1792 1:CAS:528:DC%2BD2cXivFals7Y%3D
41. Liu J, DeFranco DB (1999) Chromatin recycling of glucocorticoid receptors: Implications for multiple roles of heat shock protein 90. Mol Endocrinol 13:355-365 1:CAS:528:DyaK1MXhslWgsLg%3D
42. Liu XD, Morano KA, Thiele DJ (1999) The yeast Hsp110 family member, Sse1, is an Hsp90 cochaperone. J Biol Chem 274:26654-26660 1:CAS:528:DyaK1MXmt1alu7s%3D
43. Louvion JF, Abbas-Terki T, Picard D (1998) Hsp90 is required for pheromone signaling in yeast. Mol Biol Cell 9:3071-3083 1:CAS:528:DyaK1cXnt1GqsLY%3D
44. Machida H, Matsumoto Y, Shirai M, Kubota N (2003) Geldanamycin, an inhibitor of Hsp90, sensitizes human tumour cells to radiation. Int J Radiat Biol 79:973-980 1:CAS:528:DC%2BD2cXnvFam
45. Mayer MP, Bukau B (1999) Molecular chaperones: The busy life of Hsp90. Curr Biol 9:R322-325 1:CAS:528:DyaK1MXjs1CitL4%3D
46. Morishima Y, Murphy PJ, Li DP, Sanchez ER, Pratt WB (2000) Stepwise assembly of a glucocorticoid receptor. hsp90 heterocomplex resolves two sequential ATP-dependent events involving first hsp70 and then hsp90 in opening of the steroid binding pocket. J Biol Chem 275:18054-18060 1:CAS:528:DC%2BD3cXktlymt78%3D
47. Mumberg D, Muller R, Funk M (1995) Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds. Gene 156:119-122 1:CAS:528:DyaK2MXkvVamsb4%3D
48. Nathan DF, Lindquist S (1995) Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase. Mol Cell Biol 15:3917-3925 1:CAS:528:DyaK2MXmsVClsbc%3D
49. Nathan DF, Vos MH, Lindquist S (1997) In vivo functions of the Saccharomyces cerevisiae Hsp90 chaperone. Proc Natl Acad Sci USA 94:12949-12956 1:CAS:528:DyaK2sXnvFamsrY%3D
50. Neckers L (2002) Hsp90 inhibitors as novel cancer chemotherapeutic agents. Trends Mol Med 8:S55-S61 1:CAS:528:DC%2BD38XitlGhsb4%3D
51. Nicolet CM, Craig EA (1989) Isolation and characterization of STI1, a stress-inducible gene from Saccharomyces cerevisiae. Mol Cell Biol 9:3638-3646 1:CAS:528:DyaK3cXntFaqtg%3D%3D
52. Park E et al (1992) RAD25 (SSL2), the yeast homolog of the human xeroderma pigmentosum group B DNA repair gene, is essential for viability. Proc Natl Acad Sci USA 89:11416-11420 1:CAS:528:DyaK3sXkvVyiur4%3D
53. Pearl LH, Prodromou C (2001) Structure, function, and mechanism of the Hsp90 molecular chaperone. Adv Protein Chem 59:157-186 1:STN:280:DC%2BD387jtleiug%3D%3D
54. Pratt WB, Toft DO (2003) Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery. Exp Biol Med 228:111-133 1:CAS:528:DC%2BD3sXht1amtbY%3D
55. Prodromou C, et al (1999) Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones. EMBO J 18:754-762 1:CAS:528:DyaK1MXhslaisLg%3D
56. Prodromou C, Pearl LH (2003) Structure and functional relationships of Hsp90. Curr Cancer Drug Targets 3:301-323 1:CAS:528:DC%2BD3sXnsV2isrs%3D
57. Qiu H, Park E, Prakash L, Prakash S (1993) The Saccharomyces cerevisiae DNA repair gene RAD25 is required for transcription by RNA polymerase II. Genes Dev 7:2161-2171 1:CAS:528:DyaK2cXkslahsQ%3D%3D
58. Ranish JA, et al (2004) Identification of TFB5, a new component of general transcription and DNA repair factor IIH. Nat Genet 36:707-713 1:CAS:528:DC%2BD2cXlt1Cku7c%3D
59. Richter K, Muschler P, Hainzl O, Reinstein J, Buchner J (2003) Sti1 Is a Non-competitive Inhibitor of the Hsp90 ATPase. Binding prevents the N-terminal dimerization reaction during the atpase cycle. J Biol Chem 278:10328-10333 1:CAS:528:DC%2BD3sXitVCrsL4%3D
60. Rose MD, Novick P, Thomas JH, Botstein D, Fink GR (1987) A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene 60:237-243 1:CAS:528:DyaL1cXht1Gku74%3D
61. Rosenhagen MC et al (2003) The heat shock protein 90-targeting drug cisplatin selectively inhibits steroid receptor activation. Mol Endocrinol 17:1991-2001 1:CAS:528:DC%2BD3sXotFSrsLk%3D
62. Rothstein R (1991) Targeting, disruption, replacement and allele rescue: intergrative DNA transformation in yeast. In: Guthrie C, Fink GR (eds) Methods in enzymology: Guide to yeast genetics and molecular biology. Cold Harbor Laboratory, Cold Harbor, N.Y., pp 281-301
63. Russell JS, Burgan W, Oswald KA, Camphausen K, Tofilon PJ (2003) Enhanced cell killing induced by the combination of radiation and the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin: a multitarget approach to radiosensitization. Clin Cancer Res 9:3749-3755 1:CAS:528:DC%2BD3sXosVOksrc%3D
64. Schafer T, Strauss D, Petfalski E, Tollervey D, Hurt E (2003) The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes. EMBO J 22:1370-1380 12628929
65. Scheufler C et al (2000) Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine. Cell 101:199-210 1:CAS:528:DC%2BD3cXislKisrY%3D
66. Schiestl RH, Gietz RD (1989) High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr Genet 16:339-346 1:CAS:528:DyaK3cXpsFehsA%3D%3D
67. Schultz P, Fribourg S, Poterszman A, Mallouh V, Moras D, Egly JM (2000) Molecular structure of human TFIIH. Cell 102:599-607 1:CAS:528:DC%2BD3cXmsFWitL4%3D
68. Sherman F, Fink GR, Hicks JB (1986) Laboratory course manual for methods in yeast genetics. Cold Harbor Laboratory, Cold Harbor, N.Y.
69. Sikorski RS, Boeke JD (1991) In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeast. In: Guthrie C, Fink GR (eds) Metholds in enzymology: Guide to yeast genetics and molecular biology. Cold Harbor Laboratory, Cold Harbor, N.Y., pp 302-318
70. Sikorski RS, Hieter P (1989) A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27 1:CAS:528:DyaL1MXktVais70%3D
71. Smith DF (1993) Dynamics of heat shock protein 90-progesterone receptor binding and the disactivation loop model for steroid receptor complexes. Mol Endocrinol 7:1418-1429 1:CAS:528:DyaK2cXitlyitg%3D%3D
72. Smith DF, et al (1993) Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70. Mol Cell Biol 13:869-876 1:CAS:528:DyaK3sXps1GrtQ%3D%3D
73. Soti C, Racz A, Csermely P (2002) A Nucleotide-dependent molecular switch controls ATP binding at the C-terminal domain of Hsp90. N-terminal nucleotide binding unmasks a C-terminal binding pocket. J Biol Chem 277:7066-7075 1:CAS:528:DC%2BD38XitV2mur0%3D
74. Sweder KS, Hanawalt PC (1994) The COOH terminus of suppressor of stem loop (SSL2/RAD25) in yeast is essential for overall genomic excision repair and transcription-coupled repair. J Biol Chem 269:1852-1857 1:CAS:528:DyaK2cXhsFGlsL4%3D
75. Thomas BJ, Rothstein R (1989) Elevated recombination rates in transcriptionally active DNA. Cell 56:619-630 1:CAS:528:DyaL1MXhs1Oht7c%3D
76. MB Toledano A Delaunay B Biteau D Spector D Azevedo 2003 Oxidative stress responses in yeast In: S Hohmann, WH Mager (eds) Yeast stress responses Springer-Verlag Berlin 241-303
77. Valay JG, Simon M, Dubois MF, Bensaude O, Facca C, Faye G (1995) The KIN28 gene is required both for RNA polymerase II mediated transcription and phosphorylation of the Rpb1p CTD. J Mol Biol 249:535-544 1:CAS:528:DyaK2MXmtlKltbo%3D
78. van Brabant AJ, Stan R, Ellis NA (2000) DNA helicases, genomic instability, and human genetic disease. Annu Rev Genomics Hum Genet 1:409-459 11701636
79. Wegele H, Haslbeck M, Reinstein J, Buchner J (2003) Sti1 is a novel activator of the Ssa proteins. J Biol Chem 278:25970-25976 10.1074/ jbc.M301548200
80. Workman P (2003) Overview: Translating Hsp90 biology into Hsp90 drugs. Curr Cancer Drug Targets 3:297-300 1:CAS:528:DC%2BD3sXnsV2isro%3D
81. Yan W, Craig EA (1999) The glycine-phenylalanine-rich region determines the specificity of the yeast Hsp40 Sis1. Mol Cell Biol 19:7751-7758 1:CAS:528:DyaK1MXmvFektbk%3D
82. Young JC, Hartl FU (2000) Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co-chaperone p23. EMBO J 19:5930-5940 1:CAS:528:DC%2BD3cXovFahsrk%3D
83. Young JC, Moarefi I, Hartl FU (2001) Hsp90: A specialized but essential protein-folding tool. J Cell Biol 154:267-273 1:CAS:528:DC%2BD3MXlsVOjs7k%3D
84. Zhang L, Hach A, Wang C (1998) Molecular mechanism governing heme signaling in yeast: A higher-order complex mediates heme regulation of the transcriptional activator HAP1. Mol Cell Biol 18:3819-3828 1:CAS:528:DyaK1cXkt1Wjsrs%3D