A dopamine D4 receptor antagonist attenuates ischemia-induced neuronal cell damage via upregulation of neuronal apoptosis inhibitory protein

Journal of Cerebral Blood Flow and Metabolism

Volumn 25, Issue 7, 2005, Pages 794-806

  Okada, Yoshinori ^a,b   Sakai, Harumi ^a   Kohiki, Eri ^b   Suga, Etsuko ^b   Yanagisawa, Yoshiko ^b   Tanaka, Kazunori ^a   Hadano, Shinji ^a,b   Osuga, Hitoshi ^a,b   Ikeda, Joh E ^a,b,c  

^a TOKAI UNIVERSITY   (Japan)

^b TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Antiapoptosis; Dopamine receptor antagonist; IAP; Ischemia; NAIP; Oxidative stress

Indexed keywords

3 [[4 (4 CHLOROPHENYL) 1 PIPERAZINYL]METHYL] 1H PYRROLO[2,3 B]PYRIDINE; DOPAMINE RECEPTOR 4 ANTAGONIST; DOPAMINE RECEPTOR BLOCKING AGENT; INHIBITOR OF APOPTOSIS PROTEIN; NEURONAL APOPTOSIS INHIBITORY PROTEIN; NEUROPROTECTIVE AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; BRAIN PROTECTION; CONTROLLED STUDY; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SCREENING; ENZYME LINKED IMMUNOSORBENT ASSAY; GERBIL; HIPPOCAMPUS; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; NERVE CELL LESION; NERVE CELL NECROSIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; RNA INTERFERENCE; STROKE; TECHNIQUE;

ANIMALS; APOPTOSIS; CELL LINE; DRUG EVALUATION, PRECLINICAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GERBILLINAE; HIPPOCAMPUS; HUMANS; ISCHEMIA; MALE; NERVE TISSUE PROTEINS; NEURONAL APOPTOSIS-INHIBITORY PROTEIN; NEURONS; OXIDATIVE STRESS; PYRIDINES; PYRROLES; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4; UP-REGULATION; VITAMIN K 3;

EID: 21344432353     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600078     Document Type: Article

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