Response of memory CD8+ T cells to severe acute respiratory syndrome (SARS) coronavirus in recovered SARS patients and healthy individuals

Journal of Immunology

Volumn 175, Issue 1, 2005, Pages 591-598

  Chen, Huabiao ^a   Hou, Jinlin ^b   Jiang, Xiaodong ^c   Ma, Shiwu ^b   Meng, Minjie ^d   Wang, Baomei ^a   Zhang, Minghui ^a   Zhang, Mingxia ^b   Tang, Xiaoping ^e   Zhang, Fuchun ^e   Wan, Tao ^a   Li, Nan ^a   Yu, Yizhi ^a   Hu, Hongbo ^f   Yang, Ruifu ^g   He, Wei ^f   Wang, Xiaoning ^d   Cao, Xuetao ^a,c  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b FIRST MILITARY MEDICAL UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d SOUTHERN MEDICAL UNIVERSITY   (China)

^e LINYI PEOPLE'S HOSPITAL   (China)

^f INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^g BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR5; GAMMA INTERFERON; GRANZYME A; HERMES ANTIGEN; HLA A ANTIGEN; PERFORIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORONAVIRUS; CYTOTOXIC T LYMPHOCYTE; ENZYME RELEASE; FEMALE; HUMAN; HUMAN CELL; MALE; MEMORY CELL; PRIORITY JOURNAL; SEVERE ACUTE RESPIRATORY SYNDROME;

EID: 21244483419     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.1.591     Document Type: Article

References (51)

1. Lee, N., D. Hui, A. Wu, P. Chan, P. Cameron, G. M. Joynt, A. Ahuja, M. Y. Yung, C. B. Leung, K. F. To, et al. 2003. A major outbreak of severe acute respiratory syndrome in Hong Kong. N. Engl. J. Med. 348: 1986-1994.
2. Ksiazek, T. G., D. Erdman, C. S. Goldsmith, S. R. Zaki, T. Peret, S. Emery, S. Tong, C. Urbani, J. A. Comer, W. Lim, et al. 2003. A novel coronavirus associated with severe acute respiratory syndrome. N. Engl. J. Med. 348: 1953-1966.
3. Peiris, J. S., S. T. Lai, L. L. Poon, Y. Guan, L. Y. Yam, W. Lim, J. Nicholls, W. K. Yee, W. W. Yan, M. T. Cheung, et al. 2003. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet 361: 1319-1325.
4. Drosten, C., S. Gunther, W. Preiser, S. van der Werf, H. R. Brodt, S. Becker, H. Rabenau, M. Panning, L. Kolesnikova, R. A. Fouchier, et al. 2003. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N. Engl. J. Med. 348: 1967-1976.
5. Rota, P. A., M. S. Oberste, S. S. Monroe, W. A. Nix, R. Campagnoli, J. P. Icenogle, S. Penaranda, B. Bankamp, K. Maher, M. H. Chen, et al. 2003. Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science 300: 1394-1399.
6. Marra, M. A., S. J. Jones, C. R. Astell, R. A. Holt, A. Brooks-Wilson, Y. S. Butterfield, J. Khattra, J. K. Asano, S. A. Barber, S. Y. Chan, et al. 2003. The genome sequence of the SARS-associated coronavirus. Science 300: 1399-1404.
7. Qin, E., Q. Zhu, M. Yu, B. Fan, G. Chang, B. Si, B. Yang, W. Peng, T. Jiang, B. Liu, et al. 2003. A complete sequence and comparative analysis of a SARS-associated virus (Isolate BJ01). Chin. Sci. Bull. 48: 941-948.
8. Peiris, J. S., C. M. Chu, V. C. Cheng, K. S. Chan, I. F. Hung, L. L. Poon, K. I. Law, B. S. Tang, T. Y. Hon, C. S. Chan, et al. 2003. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet 361: 1767-1772.
9. Nicholls, J. M., L. L. Poon, K. C. Lee, W. F. Ng, S. T. Lai, C. Y. Leung, C. M. Chu, P. K. Hui, K. L. Mak, W. Lim, et al. 2003. Lung pathology of fatal severe acute respiratory syndrome. Lancet 361: 1773-1778.
10. Panesar, N. S. 2003. Lymphopenia in SARS. Lancet. 361: 1985.
11. Li, T., Z. Qiu, L. Zhang, Y. Han, W. He, Z. Liu, X. Ma, H. Fan, W. Lu, J. Xie, et al. 2004. Significant changes of peripheral T lymphocyte subsets in patients with severe acute respiratory syndrome. J. Infect. Dis. 189: 648-651.
12. Cui, W., Y. Fan, W. Wu, F. Zhang, J. Y. Wang, and A. P. Ni. 2003. Expression of lymphocytes and lymphocyte subsets in patients with severe acute respiratory syndrome. Clin. Infect. Dis. 37: 857-859.
13. + T-cell epitope SSp-1 of SARS-CoV spike protein. Blood 104: 200-206.
14. Wang, Y. D., W. Y. Sin, G. B. Xu, H. H. Yang, T. Y. Wong, X. W. Pang, X. Y. He, H. G. Zhang, J. N. Ng, C. S. Cheng, et al. 2004. T-cell epitopes in severe acute respiratory syndrome (SARS) coronavirus spike protein elicit a specific T-cell immune response in patients who recover from SARS. J. Virol. 78: 5612-5618.
15. Wang, Y. D., and W. F. Chen. 2004. Detecting specific cytotoxic T lymphocytes against SARS-coronavirus with DimerX HLA-A2:lg fusion protein. Clin. Immunol. 113: 151-154.
16. Fleischhauer, K., E. Zino, B. Mazzi, G. M. Severini, E. Benazzi, and C. Bordignon. 1996. HLA-A*02 subtype distribution in Caucasians from northern Italy: identification of A*0220. Tissue Antigens 48: 673-679.
17. Du Pasquier, R. A., M. J. Kuroda, J. E. Schmitz, Y. Zheng, K. Martin, F. W. Peyerl, M. Lifton, D. Gorgone, P. Autissier, N. L. Letvin, and I. J. Koralnik. 2003. Low frequency of cytotoxic T lymphocytes against the novel HLA-A*0201-restricted JC virus epitope VP1p36 in patients with proven or possible progressive multifocal leukoencephalopathy. J. Virol. 77: 11918-11926.
18. Day, C. L., N. P. Seth, M. Lucas, H. Appel, L. Gauthier, G. M. Lauer, G. K. Robbins, Z. M. Szczepiorkowski, D. R. Casson, R. T. Chung, et al. 2003. Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers. J. Clin. Invest. 112: 831-842.
19. + T-cell epitopes. Blood 99: 2100-2106.
20. Mongkolsapaya, J., W. Dejnirattisai, X. N. Xu, S. Vasanawathana, N. Tangthawornchaikul, A. Chairunsri, S. Sawasdivorn, T. Duangchinda, T. Dong, S. Rowland-Jones, et al. 2003. Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nat. Med. 9: 921-927.
21. Savage, P. A., J. J. Boniface, and M. M. Davis. 1999. A kinetic basis for T cell receptor repertoire selection during an immune response. Immunity 10: 485-492.
22. Davenport, M. P., C. Fazou, A. J. McMichael, and M. F. Callan. 2002. Clonal selection, clonal senescence, and clonal succession: the evolution of the T cell response to infection with a persistent virus. J. Immunol. 168: 3309-3317.
23. + T-cell memory determined by clonal burst size. Nature 369: 652-654.
24. + T cells in primary and secondary influenza pneumonia. Immunity 8: 683-691.
25. Lukacher, A. E., V. L. Braciale, and T. J. Braciale. 1984. In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific. J. Exp. Med. 160: 814-826.
26. + T cells. J. Immunol. 168: 5933-5942.
27. Janeway, C. A., and K. Bottomly. 1994. Signals and signs for lymphocytes responses. Cell 76: 275-285.
28. Celluzzi, C. M., J. I. Mayordomo, W. J. Storkus, M. T. Lotze, and L. D. Falo. 1996. Peptide-pulsed dendritic cells induce antigen-specific, CTL-mediated protective tumor immunity. J. Exp. Med. 183: 283-287.
29. Subklewe, M., A. Chahroudi, A. Schmaljohn, M. G. Kurilla, N. Bhardwaj, and R. M. Steinman. 1999. Induction of Epstein-Barr virus-specific cytotoxic T-lymphocyte responses using dendritic cells pulsed with EBNA-3A peptides or UV-inactivated, recombinant EBNA-3A vaccinia virus. Blood 94: 1372-1381.
30. Sallusto, F., D. Lenig, R. Forster, M. Lipp, and A. Lanzavecchia. 1999. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401: 708-712.
31. Champagne, P., G. S. Ogg, A. S. King, C. Knabenhans, K. Ellefsen, M. Nobile, V. Appay, G. P. Rizzardi, S. Fleury, M. Lipp, et al. 2001. Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature 410: 106-111.
32. Ding, Y., H. Wang, H. Shen, Z. Li, J. Geng, H. Han, J. Cai, X. Li, W. Kang, D. Weng, et al. 2003. The clinical pathology of severe acute respiratory syndrome (SARS): a report from China. J. Pathol. 200: 282-289.
33. Lang, Z., L. Zhang, S. Zhang, X. Meng, J. Li, C. Song, L. Sun, and Y. Zhou. 2003. Pathological study on severe acute respiratory syndrome. Chin. Med. J. 116: 976-980.
34. Lang, Z. W., L. J. Zhang, S. J. Zhang, X. Meng, J. Q. Li, C. Z. Song, L. Sun, Y. S. Zhou, and D. E. Dwyer. 2003. A clinicopathological study of three cases of severe acute respiratory syndrome (SARS). Pathology 35: 526-531.
35. Lee, C. H., R. F. Chen, J. W. Liu, W. T. Yeh, J. C. Chang, P. M. Liu, H. L. Eng, M. C. Lin, and K. D. Yang. 2004. Altered p38 mitogen-activated protein kinase expression in different leukocytes with increment of immunosuppressive mediators in patients with severe acute respiratory syndrome. J. Immunol. 172: 7841-7847.
36. Yang, H. Y., P. L. Dundon, S. R. Nahill, and R. M. Welsh. 1989. Virus-induced polyclonal cytotoxic T lymphocyte stimulation. J. Immunol. 142: 1710-1718.
37. Selin, L. K., S. R. Nahill, and R. M. Welsh. 1994. Cross-reactivities in memory cytotoxic T lymphocyte recognition of heterologous viruses. J. Exp. Med. 179: 1933-1943.
38. Klenerman, P., and R. M. Zinkernagel. 1998. Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes. Nature 394: 482-485.
39. Martinez, F. D., A. L. Wright, L. M. Taussig, C. J. Holberg, M. Halonen, and W. J. Morgan. 1995. Asthma and wheezing in the first six years of life. N. Engl. J. Med. 332: 133-138.
40. Crowe, J. E. 2001. Respiratory syncytial virus vaccine development. Vaccine 20(Suppl. 1): S32-S37.
41. Selin, L. K., S. M. Varga, I. C. Wong, and R. M. Welsh. 1998. Protective heterologous antiviral immunity and enhanced immunopathogenesis mediated by memory T cell populations. J. Exp. Med. 188: 1705-1715.
42. +-T-cell memory in mice challenged with unrelated pathogens. J. Virol. 77: 7756-7763.
43. + T cells in heterologous antiviral immunity and immunopathology in the lung. Nat. Immunol. 2: 1067-1076.
44. Van Bever, H. P., S. Y. Chng, and D. Y. Goh. 2004. Childhood severe acute respiratory syndrome, coronavirus infections and asthma. Pediatr. Allergy Immunol. 15: 206-209.
45. Wong, G. W., A. M. Li, P. C. Ng, and T. F. Fok. 2003. Severe acute respiratory syndrome in children. Pediatr. Pulmonol. 36: 261-266.
46. Marshall, E., and M. Enserink. 2004. Caution urged on SARS vaccines. Science 303: 944-946.
47. Yang, Z. Y., W. P. Kong, Y. Huang, A. Roberts, B. R. Murphy, K. Subbarao, and G. J. Nabel. 2004. A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice. Nature 428: 561-564.
48. Subbarao, K., J. McAuliffe, L. Vogel, G. Fahle, S. Fischer, K. Tatti, M. Packard, W. J. Shieh, S. Zaki, and B. Murphy. 2004. Prior infection and passive transfer of neutralizing antibody prevent replication of severe acute respiratory syndrome coronavirus in the respiratory tract of mice. J. Virol. 78: 3572-3577.
49. Kim, T. W., J. H. Lee, C. F. Hung, S. Peng, R. Roden, M. C. Wang, R. Viscidi, Y. C. Tsai, L. He, P. J. Chen, et al. 2004. Generation and characterization of DNA vaccines targeting the nucleocapsid protein of severe acute respiratory syndrome coronavirus. J. Virol. 78: 4638-4645.
50. Gao, W., A. Tamin, A. Soloff, L. D'Aiuto, E. Nwanegbo, P. D. Robbins, W. J. Bellini, S. Barratt-Boyes, and A. Gambotto. 2003. Effects of a SARS-associated coronavirus vaccine in monkeys. Lancet 362: 1895-1896.
51. Bisht, H., A. Roberts, L. Vogel, A. Bukreyev, P. L. Collins, B. R. Murphy, K. Subbarao, and B. Moss. 2004. Severe acute respiratory syndrome coronavirus spike protein expressed by attenuated vaccinia virus protectively immunizes mice. Proc. Natl. Acad. Sci. USA 101: 6641-6646.