Clonal selection, clonal senescence, and clonal succession: The evolution of the T cell response to infection with a persistent virus

Journal of Immunology

Volumn 168, Issue 7, 2002, Pages 3309-3317

  Davenport, Miles P ^a   Fazou, Chrysoula ^a   McMichael, Andrew J ^a   Callan, Margaret F C ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL CYCLE; CELL DIVISION; CELL POPULATION; CELL SPECIFICITY; CELL SURVIVAL; CLINICAL ARTICLE; CLONAL VARIATION; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ACTIVITY; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MATHEMATICAL MODEL; MEMORY CELL; MOLECULAR CLONING; MOLECULAR EVOLUTION; PRIORITY JOURNAL; PROGENY; T LYMPHOCYTE; VIRUS INFECTION; VIRUS REPLICATION;

EID: 0036533483     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.7.3309     Document Type: Article

References (34)

1. Single-cell PCR analysis of TCR repertoires selected by antigen in vivo: A high magnitude CD8 response is comprised of very few clones
2. Antigen-specific development of primary and memory T cells in vivo
3. Functional maturation of an antiviral cytotoxic T-cell response
4. Evolution of a complex T cell receptor repertoire during primary and recall bacterial infection
5. Conserved T cell receptor repertoire in primary and memory CD8 T cell responses to an acute viral infection
6. A kinetic basis for T cell receptor repertoire selection during an immune response
7. T cell affinity maturation by selective expansion during infection
8. + T-cell memory determined by clonal burst size
9. + T cells during the primary immune response to Epstein-Barr virus in vivo
10. + T cells in acute infectious mononucleosis
11. + T cells specific for EBV in healthy virus carriers
12. + T-cell selection, function, and death in the primary immune response in vivo
13. Epitope focusing in the primary cytotoxic T cell response to Epstein-Barr virus and its relationship to T cell memory
14. Ageing of lymphocytes and lymphocytes in the aged
15. Population dynamics of immune responses to persistent viruses
16. Antigenic oscillations and shifting immunodominance in HIV-1 infections
17. T cell response to Epstein-Barr virus transactivators in chronic rheumatoid arthritis
18. Specific cytotoxic T lymphocytes recognize the immediate-early transactivator Zta of Epstein-Barr virus
19. An Epstein-Barr virus-specific cytotoxic T cell epitope in EBNA 3A
20. T cell death and memory
21. Counting antigen-specific CD8 T cells: A reevalution of bystander activation during viral infection
22. Decay kinetics of human immunodeficiency virus specific effector cytotoxic T lymphocytes after combination antiretroviral therapy
23. Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation
24. + T cell differentiation: Initial antigen encounter triggers a developmental program in naive cells
25. + T cell response in vivo
26. Kinetics of T-cell receptor binding to peptide/I-Ek complexes: Correlation of the dissociation rate with T-cell responsiveness
27. A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists
28. Individual variations in the murine T cell response to a specific peptide reflect variability in naive repertoires
29. + T cells
30. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells
31. Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes
32. + T cells upon acute versus persistent viral infection
33. + T cells
34. Negative selection during the peripheral immune response to antigen