SOCS1 and SHP1 hypermethylation in mantle cell lymphoma and follicular lymphoma: Implications for epigenetic activation of the Jak/STAT pathway [2]

Leukemia

Volumn 18, Issue 2, 2004, Pages 356-358

  Chim, C S ^a   Wong, K Y ^a   Loong, F ^a   Srivastava, Gopesh ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; JANUS KINASE; PROTEIN BCL 2; PROTEIN TYROSINE PHOSPHATASE; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING;

B CELL LYMPHOMA; CANCER INHIBITION; CARCINOGENESIS; CELL TRANSFORMATION; CHROMOSOME 11Q; CHROMOSOME 12P; CHROMOSOME TRANSLOCATION 11; CHROMOSOME TRANSLOCATION 14; DNA METHYLATION; ENZYME ACTIVATION; FOLLICULAR LYMPHOMA; GENE MUTATION; HUMAN; LETTER; MANTLE CELL LYMPHOMA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 1242307338     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2403216     Document Type: Letter

References (8)

1. Sanchez-Beato M, Sanchez-Aguilera A, Piris MA. Cell cycle deregulation in B-cell lymphomas. Blood 2003; 101: 1220-1235.
2. Ward AC, Touw I, Yoshimura A. The Jak-Stat pathway in normal and perturbed hematopoiesis. Blood 2000; 95: 19-29.
3. Alexander WS. Suppressors of cytokine signaling (SOCS) in the immune system. Nat Rev Immunol 2002; 2: 410-416.
4. Wu C, Sun M, Liu L, Zhou GW. The function of the protein tyrosine phosphatase SHP1 in cancer. Gene 2003; 306: 1-12.
5. Chim CS, Liang R, Tam C, Kwong YL. p15 and p16 promoter methylation in acute promyelocytic leukemia. J Clin Oncol 2001; 19: 2033-2040.
6. Nagai H, Naka T, Terada Y, Komazaki T, Yabe A, Jin E et al. Hypermethylation associated with inactivation of the SOCS1 gene, a JAK/STAT inhibitor, in human hepatoblastomas. J Hum Genet 2003; 48: 65-69.
7. Oka T, Ouchida M, Koyama M, Ogama Y, Takada S, Nakatani Y et al. Gene silencing of the tyrosine phosphatase SHP1 gene by aberrant methylation in leukemias/lymphomas. Cancer Res 2002; 62: 6390-6394.
8. Veillette A, Latour S, Davidson D. Negative regulation of immunoreceptor signaling. Annu Rev Immunol 2002; 20: 669-707.