Three-dimensional quantitative structure-activity relationship analyses of β-lactam antibiotics and tripeptides as substrates of the mammalian H +/peptide cotransporter PEPT1

Journal of Medicinal Chemistry

Volumn 48, Issue 13, 2005, Pages 4410-4419

  Biegel, Annegret ^a   Gebauer, Sabine ^a   Hartrodt, Bianka ^a   Brandsch, Matthias ^a   Neubert, Klaus ^a   Thondorf, Iris ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; AMPICILLIN; BETA LACTAM ANTIBIOTIC; CEFACLOR; CEFADROXIL; CEFALEXIN; CEFALOTIN; CEFAMANDOLE; CEFAPIRIN; CEFAZOLIN; CEFEPIME; CEFIXIME; CEFMETAZOLE; CEFODIZIME; CEFOTAXIME; CEFOXITIN; CEFPIROME; CEFPODOXIME; CEFRADINE; CEFTIBUTEN; CEFTRIAXONE; CEFUROXIME; CLOXACILLIN; CYCLACILLIN; DICLOXACILLIN; FLUCLOXACILLIN; LATAMOXEF; METAMPICILLIN; OXACILLIN; PENICILLIN G; PENICILLIN V; PEPTIDE TRANSPORTER 1; PHENETICILLIN; PIPERACILLIN; TRIPEPTIDE;

ARTICLE; BINDING AFFINITY; DRUG BINDING; DRUG BINDING SITE; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; QUANTITATIVE ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANIMALS; BETA-LACTAMS; CELL LINE, TUMOR; DIPEPTIDES; DRUG DESIGN; HUMANS; MAMMALS; MODELS, MOLECULAR; OLIGOPEPTIDES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SYMPORTERS;

EID: 21244441988     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm048982w     Document Type: Article

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