Mapping the binding site of the small intestinal peptide carrier (PepT1) using comparative molecular field analysis

Receptors and Channels

Volumn 6, Issue 3, 1998, Pages 189-200

  Swaan, Peter W ^a,b   Koops, Bart C ^a,c   Moret, Ed E ^a   Tukker, Josef J ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b OHIO STATE UNIVERSITY   (United States)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Carrier mediated transport; CoMFA; Intestinal absorption; Molecular modeling; PepT1; Peptide transporter; QSAR; Structure transport relationship

Indexed keywords

PEPTIDE;

ARTICLE; BINDING SITE; CELL TRANSPORT; CHEMICAL STRUCTURE; CORRELATION FUNCTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; HUMAN; HYDROPHOBICITY; INTESTINE ABSORPTION; MOLECULAR MODEL; PERMEABILITY; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SMALL INTESTINE;

BINDING SITES; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELL MEMBRANE PERMEABILITY; ELECTROSTATICS; INTESTINE, SMALL; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OLIGOPEPTIDES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SYMPORTERS;

EID: 0032466466     PISSN: 10606823     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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