Structural requirements for determining the substrate affinity of peptide transporters PEPT1 and PEPT2

Pflugers Archiv European Journal of Physiology

Volumn 440, Issue 5, 2000, Pages 679-684

  Terada, Tomohiro ^a   Sawada, Kyoko ^a   Irie, Megumi ^a   Saito, Hideyuki ^a   Hashimoto, Yukiya ^a   Inui, Ken Ichi ^a  

^a KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

Cyclic dipeptides; Di and tripeptides; Peptide transporters; Substrate affinity; or Carbonyl function

Indexed keywords

AMINO ACID; AMINOLEVULINIC ACID; BETA LACTAM ANTIBIOTIC; DIPEPTIDE; GLYCYLSARCOSINE; TETRAPEPTIDE; VALACICLOVIR;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BRUSH BORDER; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN TRANSPORT; RABBIT; RAT; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

EID: 0033812060     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240000339     Document Type: Article

References (25)

1. +/peptide symporter PepT1 expressed in Xenopus laevis oocytes
2. Electrophysiological analysis of the function of the mammalian renal peptide transporter expressed in Xenopus laevis oocytes
3. +/peptide cotransport system, PEPT1
4. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
5. 50) of an enzymatic reaction
6. Cellular and molecular mechanisms of renal peptide transport
7. Delta-aminolevulinic acid transport by intestinal and renal peptide transporters and its physiological and clinical implications
8. Minimal molecular determinants of substrates for recognition by the intestinal peptide transporter
9. Differential recognition of β-lactam antibiotics by intestinal and renal peptide transporters, PEPT1 and PEPT2
10. Valacyclovir: A substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2
11. Cellular uptake mechanism of amino acid ester prodrugs in Caco-2/hPEPT1 cells overexpressing a human peptide transporter
12. Structural requirements for interaction with oligopeptide transporter in Caco-2 cells
13. Dipeptide transporters
14. Peptide transporters in the intestine and the kidney
15. Intestinal absorption of stable cyclic dipeptides by the oligopeptide transporter in rat
16. +/peptide cotransporter in rat digestive tract
17. Proton/peptide cotransporter (PEPT2) from human kidney: Functional characterization and chromosomal localization
18. +/peptide cotransporter mediating absorption of β-lactam antibiotics in the intestine and kidney
19. Molecular cloning and tissue distribution of rat peptide transporter PEPT2
20. Recognition of 1-amino acid ester compounds by rat peptide transporters PEPT1 and PEPT2
21. Localization of PEPT1 and PEPT2 proton-coupled oligopeptide transporter mRNA and protein in rat kidney
22. +/peptide cotransporters in rat renal brush-border membranes
23. +/peptide cotransporters, PEPT1 and PEPT2
24. +/peptide cotransporter PEPT1: Localization of PEPT1 and transport of β-lactam antibiotics
25. 1 cells