메뉴 건너뛰기




Volumn 9, Issue 2, 2005, Pages 114-121

Connective tissue growth factor mediates the profibrotic effects of transforming growth factor-β produced by tubular epithelial cells in response to high glucose

Author keywords

Connective tissue growth factor; Fibroblasts; Fibrogenesis; Glucose; Transforming growth factor ; Tubular epithelial cells

Indexed keywords

COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; FIBRONECTIN; GLUCOSE; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRANSFORMING GROWTH FACTOR BETA;

EID: 21044443167     PISSN: 13421751     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10157-005-0347-x     Document Type: Article
Times cited : (47)

References (40)
  • 2
    • 0028218461 scopus 로고
    • Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-β
    • Ziyadeh FN, Sharma K, Ericksen M, Wolf G. Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-β. J Clin Invest 1994;93:536-42.
    • (1994) J Clin Invest , vol.93 , pp. 536-542
    • Ziyadeh, F.N.1    Sharma, K.2    Ericksen, M.3    Wolf, G.4
  • 3
    • 0002779849 scopus 로고    scopus 로고
    • Therapy with antisense TGF-βl oligodoxynucleotides reduces kidney weight and matrix mRNAs in diabetic mice
    • DC Han BB Hoffman SW Hong J Guo FN Ziyadeh 2000 Therapy with antisense TGF-βl oligodoxynucleotides reduces kidney weight and matrix mRNAs in diabetic mice Am J Physiol 278 F628 34
    • (2000) Am J Physiol , vol.278 , pp. 628-34
    • Han, D.C.1    Hoffman, B.B.2    Hong, S.W.3    Guo, J.4    Ziyadeh, F.N.5
  • 4
    • 17344374676 scopus 로고    scopus 로고
    • Homeostasis of extracellular matrix by TGF-beta and lefty
    • S Tabibzadeh 2002 Homeostasis of extracellular matrix by TGF-beta and lefty Front Biosci 7 1231 46
    • (2002) Front Biosci , vol.7 , pp. 1231-46
    • Tabibzadeh, S.1
  • 5
    • 0031225015 scopus 로고    scopus 로고
    • Connective tissue growth factor: A mediator of TGF-beta action on fibroblasts
    • GR Grotendorst 1997 Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts Cytokine Growth Factor Rev 8 171 9
    • (1997) Cytokine Growth Factor Rev , vol.8 , pp. 171-9
    • Grotendorst, G.R.1
  • 6
    • 0344844508 scopus 로고    scopus 로고
    • Long-term exposure of proximal tubular epithelial cells to glucose induces transforming growth factor-β1 synthesis via an autocrine PDGF loop
    • Fraser D, Brunskill N, Ito T, Phillips A. Long-term exposure of proximal tubular epithelial cells to glucose induces transforming growth factor-β1 synthesis via an autocrine PDGF loop. Am J Pathol 2003;163:2565-74.
    • (2003) Am J Pathol , vol.163 , pp. 2565-2574
    • Fraser, D.1    Brunskill, N.2    Ito, T.3    Phillips, A.4
  • 7
    • 0035136844 scopus 로고    scopus 로고
    • TGF-beta 1 induces proliferation in human renal fibroblasts via induction of basic fibroblast growth factor (FGF-2
    • F Strutz M Zeisberg A Renziehausen B Raschke V Becker C Van Kooten 2001 TGF-beta 1 induces proliferation in human renal fibroblasts via induction of basic fibroblast growth factor (FGF-2 Kidney Int 59 579 92
    • (2001) Kidney Int , vol.59 , pp. 579-92
    • Strutz, F.1    Zeisberg, M.2    Renziehausen, A.3    Raschke, B.4    Becker, V.5    Van Kooten, C.6
  • 9
    • 0036236672 scopus 로고    scopus 로고
    • Localization of connective tissue growth factor mRNA in human diabetic nephropathy by in situ hybridization
    • T Umezono D Suzuki M Toyoda SY Zhang H Sakai 2002 Localization of connective tissue growth factor mRNA in human diabetic nephropathy by in situ hybridization Clin Exp Nephrol 6 13 20
    • (2002) Clin Exp Nephrol , vol.6 , pp. 13-20
    • Umezono, T.1    Suzuki, D.2    Toyoda, M.3    Zhang, S.Y.4    Sakai, H.5
  • 10
    • 0033802165 scopus 로고    scopus 로고
    • Connective tissue growth factor: Potential role in glomerulosclerosis and tublointerstitial fibrosis
    • S Gupta MR Clarkson J Duggan HR Brady 2000 Connective tissue growth factor: potential role in glomerulosclerosis and tublointerstitial fibrosis Kidney Int 58 1389 99
    • (2000) Kidney Int , vol.58 , pp. 1389-99
    • Gupta, S.1    Clarkson, M.R.2    Duggan, J.3    Brady, H.R.4
  • 11
    • 0038035643 scopus 로고    scopus 로고
    • GF/Hcs24 as a multifunctional growth factor for fibroblasts, chondrocytes and vascular endothelial cells
    • M Takigawa 2003 GF/Hcs24 as a multifunctional growth factor for fibroblasts, chondrocytes and vascular endothelial cells Drug News Perspect 16 11 21
    • (2003) Drug News Perspect , vol.16 , pp. 11-21
    • Takigawa, M.1
  • 12
    • 0036775477 scopus 로고    scopus 로고
    • Gene regulation of connective growth factor: New targets for antifibrotic therapy?
    • IE Blom R Goldschmeding A Leask 2002 Gene regulation of connective growth factor: new targets for antifibrotic therapy? Matrix Biol 21 473 82
    • (2002) Matrix Biol , vol.21 , pp. 473-82
    • Blom, I.E.1    Goldschmeding, R.2    Leask, A.3
  • 14
    • 0041322515 scopus 로고    scopus 로고
    • Urinary connective tissue growth factor excretion in patients with type 1 diabetes and nephropathy
    • RE Gilbert A Akdeniz S Weitz WR Usinger C Molineaux SE Jones 2003 Urinary connective tissue growth factor excretion in patients with type 1 diabetes and nephropathy Diabetes Care 26 2634 6
    • (2003) Diabetes Care , vol.26 , pp. 2634-6
    • Gilbert, R.E.1    Akdeniz, A.2    Weitz, S.3    Usinger, W.R.4    Molineaux, C.5    Jones, S.E.6
  • 16
    • 0037315742 scopus 로고    scopus 로고
    • Hepatocyte growth factor counteracts transforming growth factor-β1, through attenuation of connective tissue growth factor induction, and prevents renal fibrogenesis in 5/6 nephrectomized mice
    • T Inoue H Okada T Kobayashi Y Watanabe Y Kanno JB Kopp 2003 Hepatocyte growth factor counteracts transforming growth factor-β1, through attenuation of connective tissue growth factor induction, and prevents renal fibrogenesis in 5/6 nephrectomized mice FASEB J 17 268 70
    • (2003) FASEB J , vol.17 , pp. 268-70
    • Inoue, T.1    Okada, H.2    Kobayashi, T.3    Watanabe, Y.4    Kanno, Y.5    Kopp, J.B.6
  • 17
    • 0034761986 scopus 로고    scopus 로고
    • Pathogenesis of diabetic nephropathy: Focus on transforming growth factor-β and connective tissue growth factor
    • OV Sakharova MW Taal BM Brenner 2001 Pathogenesis of diabetic nephropathy: focus on transforming growth factor-β and connective tissue growth factor Curr Opin nephrol Hypertens 10 727 38
    • (2001) Curr Opin Nephrol Hypertens , vol.10 , pp. 727-38
    • Sakharova, O.V.1    Taal, M.W.2    Brenner, B.M.3
  • 18
    • 0037404251 scopus 로고    scopus 로고
    • Involvement of ERK pathway in albumin-induced MCP-1 expression in mouse proximal tubular cells
    • K Takaya D Koya M Isono T Sugimoto T Sugaya A Kashiwagi 2003 Involvement of ERK pathway in albumin-induced MCP-1 expression in mouse proximal tubular cells Am J Physiol 284 F1037 45
    • (2003) Am J Physiol , vol.284 , pp. 1037-45
    • Takaya, K.1    Koya, D.2    Isono, M.3    Sugimoto, T.4    Sugaya, T.5    Kashiwagi, A.6
  • 19
    • 0347360288 scopus 로고    scopus 로고
    • ERK and p38 mediate high-glucose-induced hypertrophy and TGF-beta expression in renal tubular cells
    • H Fujita S Omori K Ishikura M Hida M Awazu 2004 ERK and p38 mediate high-glucose-induced hypertrophy and TGF-beta expression in renal tubular cells Am J Physiol Renal Physiol 286 F120 6
    • (2004) Am J Physiol Renal Physiol , vol.286 , pp. 120-6
    • Fujita, H.1    Omori, S.2    Ishikura, K.3    Hida, M.4    Awazu, M.5
  • 20
    • 0034947508 scopus 로고    scopus 로고
    • Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice
    • Y Yamamoto I Kato T Doi H Yonekura S Ohashi M Takeuchi 2001 Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice J Clin Invest 108 261 8
    • (2001) J Clin Invest , vol.108 , pp. 261-8
    • Yamamoto, Y.1    Kato, I.2    Doi, T.3    Yonekura, H.4    Ohashi, S.5    Takeuchi, M.6
  • 22
    • 21044452015 scopus 로고    scopus 로고
    • Endogenous HGF likely counteracts TGF-β1 to prevent progression of renal injury in 5/6 nephrectomized mice (abstract)
    • T Inoue H Okada Y Kanno T Nakamura JB Kopp H Suzuki 2000 Endogenous HGF likely counteracts TGF-β1 to prevent progression of renal injury in 5/6 nephrectomized mice (abstract) J Am Soc Nephrol 11 621
    • (2000) J Am Soc Nephrol , vol.11 , pp. 621
    • Inoue, T.1    Okada, H.2    Kanno, Y.3    Nakamura, T.4    Kopp, J.B.5    Suzuki, H.6
  • 23
    • 0033957976 scopus 로고    scopus 로고
    • Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis
    • BL Riser M Denichilo P Cortes C Baker JM Grondini J Yee 2000 Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis J Am Soc Nephrol 11 25 38
    • (2000) J Am Soc Nephrol , vol.11 , pp. 25-38
    • Riser, B.L.1    Denichilo, M.2    Cortes, P.3    Baker, C.4    Grondini, J.M.5    Yee, J.6
  • 24
    • 0033605162 scopus 로고    scopus 로고
    • Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells
    • M Murphy C Godson S Cannon S Kato HS Mackenzie F Martin 1999 Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells J Biol Chem 274 5830 4
    • (1999) J Biol Chem , vol.274 , pp. 5830-4
    • Murphy, M.1    Godson, C.2    Cannon, S.3    Kato, S.4    MacKenzie, H.S.5    Martin, F.6
  • 25
    • 0345275808 scopus 로고    scopus 로고
    • Connective tissue growth factor and igf-1 are produced by human renal fibroblasts and cooperate in the induction of collagen production by high glucose
    • S Lam RN Der Van Geest NA Verhagen FA Van Nieuwenhoven IE Blom J Aten 2003 Connective tissue growth factor and igf-1 are produced by human renal fibroblasts and cooperate in the induction of collagen production by high glucose Diabetes 52 2975 83
    • (2003) Diabetes , vol.52 , pp. 2975-83
    • Lam, S.1    Der Van Geest, R.N.2    Verhagen, N.A.3    Van Nieuwenhoven, F.A.4    Blom, I.E.5    Aten, J.6
  • 27
    • 0031655355 scopus 로고    scopus 로고
    • Transcriptional activation of transforming growth factor-β1 in mesangial cell culture by high glucose concentration
    • BB Hoffman K Sharma Y Zhu FN Ziyadeh 1998 Transcriptional activation of transforming growth factor-β1 in mesangial cell culture by high glucose concentration Kidney Int 54 1107 16
    • (1998) Kidney Int , vol.54 , pp. 1107-16
    • Hoffman, B.B.1    Sharma, K.2    Zhu, Y.3    Ziyadeh, F.N.4
  • 28
    • 0026164948 scopus 로고
    • Structure, mapping, and expression of fisp-12, a growth factor-inducible gene encoding a secreted cysteine-rich protein
    • RP Ryseck H Macdonald-Bravo MG Mattei R Bravo 1991 Structure, mapping, and expression of fisp-12, a growth factor-inducible gene encoding a secreted cysteine-rich protein Cell Growth Differ 2 225 33
    • (1991) Cell Growth Differ , vol.2 , pp. 225-33
    • Ryseck, R.P.1    MacDonald-Bravo, H.2    Mattei, M.G.3    Bravo, R.4
  • 31
    • 0034710891 scopus 로고    scopus 로고
    • Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Spl glycosylation
    • XL Du D Edelstein L Rossetti IG Fantus H Goldberg F Ziyadeh 2000 Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Spl glycosylation Proc Natl Acad Sci USA 97 12222 6
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12222-6
    • Du, X.L.1    Edelstein, D.2    Rossetti, L.3    Fantus, I.G.4    Goldberg, H.5    Ziyadeh, F.6
  • 32
    • 0026502932 scopus 로고
    • Elevated glucose stimulates TGF-beta gene expression and bioactivity in proximal tubule
    • MV Rocco Y Chen S Goldfarb FN Ziyadeh 1992 Elevated glucose stimulates TGF-beta gene expression and bioactivity in proximal tubule Kidney Int 41 107 14
    • (1992) Kidney Int , vol.41 , pp. 107-14
    • Rocco, M.V.1    Chen, Y.2    Goldfarb, S.3    Ziyadeh, F.N.4
  • 33
    • 0029924637 scopus 로고    scopus 로고
    • Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice
    • K Sharma Y Jin J Guo FN Ziyadeh 1996 Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice Diabetes 45 522 30
    • (1996) Diabetes , vol.45 , pp. 522-30
    • Sharma, K.1    Jin, Y.2    Guo, J.3    Ziyadeh, F.N.4
  • 34
    • 0036073109 scopus 로고    scopus 로고
    • High glucose-enhanced activation of mesangial cell p38 MAPK by ET-1, ANG II, and platelet-derived growth factor
    • E Tsiani P Lekas IG Fantus J Dlugosz C Whiteside 2002 High glucose-enhanced activation of mesangial cell p38 MAPK by ET-1, ANG II, and platelet-derived growth factor Am J Physiol 282 E161 9
    • (2002) Am J Physiol , vol.282 , pp. 161-9
    • Tsiani, E.1    Lekas, P.2    Fantus, I.G.3    Dlugosz, J.4    Whiteside, C.5
  • 35
    • 0027229995 scopus 로고
    • Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair
    • A Igarashi H Okochi DM Bradham GR Grotendorst 1993 Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair Mol Biol Cell 4 637 45
    • (1993) Mol Biol Cell , vol.4 , pp. 637-45
    • Igarashi, A.1    Okochi, H.2    Bradham, D.M.3    Grotendorst, G.R.4
  • 36
    • 0347511753 scopus 로고    scopus 로고
    • Mediators of diabetic renal disease: The case for THF-β as the major mediator
    • FN Ziyadeh 2004 Mediators of diabetic renal disease: the case for THF-β as the major mediator J Am Soc Nephrol 15 S55 7
    • (2004) J Am Soc Nephrol , vol.15 , pp. 55-7
    • Ziyadeh, F.N.1
  • 37
    • 21044454845 scopus 로고    scopus 로고
    • Connective tissue growth factor expressed in tubular epithelium plays a pivotal role in renal fibrogenesis
    • H Okada T Kikuta T Kobayashi T Inoue Y Kanno M Takigawa 2005 Connective tissue growth factor expressed in tubular epithelium plays a pivotal role in renal fibrogenesis J. Am Soc Nephrol 16 133 43
    • (2005) J. Am Soc Nephrol , vol.16 , pp. 133-43
    • Okada, H.1    Kikuta, T.2    Kobayashi, T.3    Inoue, T.4    Kanno, Y.5    Takigawa, M.6
  • 38
    • 0034951422 scopus 로고    scopus 로고
    • Connective tissue growth factor in tubulointerstitial injury of diabetic nephropathy
    • S Wang M Denichilo C Brubaker R Hirschberg 2001 Connective tissue growth factor in tubulointerstitial injury of diabetic nephropathy Kidney Int 60 96 105
    • (2001) Kidney Int , vol.60 , pp. 96-105
    • Wang, S.1    Denichilo, M.2    Brubaker, C.3    Hirschberg, R.4
  • 39
    • 0037407520 scopus 로고    scopus 로고
    • Extracellular matrix metabolism in diabetic nephropathy
    • RM Mason NA Wahab 2003 Extracellular matrix metabolism in diabetic nephropathy J Am Soc Nephrol 14 1358 73
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1358-73
    • Mason, R.M.1    Wahab, N.A.2
  • 40
    • 0036051343 scopus 로고    scopus 로고
    • Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta
    • JG Abreu NI Ketpura B Reversade EM De Robertis 2002 Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta Nat Cell Biol 4 599 604
    • (2002) Nat Cell Biol , vol.4 , pp. 599-604
    • Abreu, J.G.1    Ketpura, N.I.2    Reversade, B.3    De Robertis, E.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.