Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23

EMBO Journal

Volumn 23, Issue 18, 2004, Pages 3689-3699

  MacPherson, David ^a   Kim, Jungho ^b   Kim, Teresa ^a   Rhee, Byung Kirl ^b   Van Oostrom, Conny Th M ^c   DiTullio Jr , Richard A ^d,e   Venere, Monica ^d,e   Halazonetis, Thanos D ^d,e   Bronson, Roderick ^f   De Vries, Annemieke ^c   Fleming, Mark ^g   Jacks, Tyler ^a,h  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Sogang University   (South Korea)

^c NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^d WISTAR INSTITUTE   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f TUFTS UNIVERSITY   (United States)

^g BOSTON CHILDREN S HOSPITAL   (United States)

^h HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Apoptosis; Chk2; Lymphoma; p53; Phosphoryrlation

Indexed keywords

ALANINE; PROTEIN MDM2; PROTEIN P53; REGULATOR PROTEIN; SERINE; TUMOR SUPPRESSOR PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; B CELL LYMPHOMA; B LYMPHOCYTE; BRAIN DEVELOPMENT; CELL LINEAGE; CEREBELLUM; CONTROLLED STUDY; DELETION MUTANT; FIBROBLAST; GENE LOCUS; GENE TARGETING; LIFESPAN; MITOSIS INHIBITION; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; THYMOCYTE;

ANIMALS; APOPTOSIS; CELL CYCLE; CELLS, CULTURED; CEREBELLUM; DNA DAMAGE; FEMALE; FIBROBLASTS; HOMOZYGOTE; INFRARED RAYS; LYMPHOMA, B-CELL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHORYLATION; POINT MUTATION; SERINE; SURVIVAL RATE; THYMUS GLAND; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; MURINAE;

EID: 20844451888     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600363     Document Type: Article

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