-
2
-
-
0037106514
-
Chemotherapy for advanced non-small-cell lung cancer: Who, what, when, why?
-
P.A. Bunn Jr Chemotherapy for advanced non-small-cell lung cancer Who, what, when, why? J Clin Oncol 20 suppl 18 2002 23s 33s
-
(2002)
J Clin Oncol
, vol.20
, Issue.18 SUPPL.
-
-
Bunn Jr., P.A.1
-
3
-
-
0037106273
-
Targeting the epidermal growth factor receptor for cancer therapy
-
J. Mendelsohn Targeting the epidermal growth factor receptor for cancer therapy J Clin Oncol 20 suppl 18 2002 1s 13s
-
(2002)
J Clin Oncol
, vol.20
, Issue.18 SUPPL.
-
-
Mendelsohn, J.1
-
4
-
-
0038718522
-
Developing inhibitors of the epidermal growth factor receptor for cancer treatment
-
V. Grünwald, M. Hidalgo Developing inhibitors of the epidermal growth factor receptor for cancer treatment J Natl Cancer Inst 95 2003 851 867
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 851-867
-
-
Grünwald, V.1
Hidalgo, M.2
-
5
-
-
0036780251
-
Clinical translation of angiogenesis inhibitors
-
R. Kerbel, J. Folkman Clinical translation of angiogenesis inhibitors Nat Rev Cancer 2 2002 727 739
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 727-739
-
-
Kerbel, R.1
Folkman, J.2
-
6
-
-
0036488496
-
Specialization of tumour vasculature
-
E. Ruoslahti Specialization of tumour vasculature Nat Cancer Rev 2 2002 83 90
-
(2002)
Nat Cancer Rev
, vol.2
, pp. 83-90
-
-
Ruoslahti, E.1
-
7
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
J. Schlessinger Cell signaling by receptor tyrosine kinases Cell 103 2000 211 225
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
8
-
-
0034600849
-
The ErbB signaling network: Receptor heterodimerization in development and cancer
-
M.A. Olayioye, R.M. Neve, H.A. Lane The ErbB signaling network Receptor heterodimerization in development and cancer EMBO J 19 2000 3159 3167
-
(2000)
EMBO J
, vol.19
, pp. 3159-3167
-
-
Olayioye, M.A.1
Neve, R.M.2
Lane, H.A.3
-
9
-
-
0024399929
-
Expression of epidermal growth factor receptor (EGF-R) in non-small cell lung cancer. Use of archival tissue and correlation of EGF-R with histology, tumour size, node status and survival
-
H. Dazzi, P.S. Hasleton, N. Thatcher Expression of epidermal growth factor receptor (EGF-R) in non-small cell lung cancer. Use of archival tissue and correlation of EGF-R with histology, tumour size, node status and survival Br J Cancer 59 1989 746 749
-
(1989)
Br J Cancer
, vol.59
, pp. 746-749
-
-
Dazzi, H.1
Hasleton, P.S.2
Thatcher, N.3
-
10
-
-
0028136407
-
Prognostic influence of the co-expression of epidermal growth factor receptor and c-erbB-2 protein in human lung adenocarcinoma
-
M. Tateishi, T. Ishida, S. Kohdono Prognostic influence of the co-expression of epidermal growth factor receptor and c-erbB-2 protein in human lung adenocarcinoma Surg Oncol 3 1994 109 113
-
(1994)
Surg Oncol
, vol.3
, pp. 109-113
-
-
Tateishi, M.1
Ishida, T.2
Kohdono, S.3
-
11
-
-
17444442088
-
Immunocytochemical markers in stage I lung cancer: Relevance to prognosis
-
U. Pastorino, S. Andreola, E. Tagliabue Immunocytochemical markers in stage I lung cancer Relevance to prognosis J Clin Oncol 15 1997 2858 2865
-
(1997)
J Clin Oncol
, vol.15
, pp. 2858-2865
-
-
Pastorino, U.1
Andreola, S.2
Tagliabue, E.3
-
12
-
-
0030980781
-
Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor alpha is frequent in resectable non-small cell lung cancer but does not predict tumor progression
-
V. Rusch, D. Klimstra, E. Venkatraman Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor alpha is frequent in resectable non-small cell lung cancer but does not predict tumor progression Clin Cancer Res 3 1997 515 522
-
(1997)
Clin Cancer Res
, vol.3
, pp. 515-522
-
-
Rusch, V.1
Klimstra, D.2
Venkatraman, E.3
-
13
-
-
0031979703
-
Do molecular markers predict survival in non-small-cell lung cancer?
-
T.M. Greatens, G.A. Niehans, J.B. Rubins Do molecular markers predict survival in non-small-cell lung cancer? Am J Respir Crit Care Med 157 1998 1093 1097
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1093-1097
-
-
Greatens, T.M.1
Niehans, G.A.2
Rubins, J.B.3
-
14
-
-
0031861210
-
Enzyme-linked immunosorbent assay of epidermal growth factor receptor in lung cancer: Comparisons with immunohistochemistry, clinicopathological features and prognosis
-
P. Pfeiffer, E. Nexo, S.M. Bentzen Enzyme-linked immunosorbent assay of epidermal growth factor receptor in lung cancer Comparisons with immunohistochemistry, clinicopathological features and prognosis Br J Cancer 78 1998 96 99
-
(1998)
Br J Cancer
, vol.78
, pp. 96-99
-
-
Pfeiffer, P.1
Nexo, E.2
Bentzen, S.M.3
-
15
-
-
0031963988
-
Prognostic value of ERBB-1, VEGF, cyclin A, FOS, JUN and MYC in patients with squamous cell lung carcinomas
-
M. Volm, W. Rittgen, P. Drings Prognostic value of ERBB-1, VEGF, cyclin A, FOS, JUN and MYC in patients with squamous cell lung carcinomas Br J Cancer 77 1998 663 669
-
(1998)
Br J Cancer
, vol.77
, pp. 663-669
-
-
Volm, M.1
Rittgen, W.2
Drings, P.3
-
16
-
-
0031907022
-
Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely resected stage I-IIIA non-small-cell lung cancer: Amphiregulin and microvessel count are independent prognostic indicators of survival
-
G. Fontanini, M. De Laurentiis, S. Vignati Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely resected stage I-IIIA non-small-cell lung cancer Amphiregulin and microvessel count are independent prognostic indicators of survival Clin Cancer Res 4 1998 241 249
-
(1998)
Clin Cancer Res
, vol.4
, pp. 241-249
-
-
Fontanini, G.1
De Laurentiis, M.2
Vignati, S.3
-
17
-
-
0033015810
-
Study of prognostic predictors for non-small cell lung cancer
-
X.L. Fu, X.Z. Zhu, D.R. Shi Study of prognostic predictors for non-small cell lung cancer Lung Cancer 23 1999 143 152
-
(1999)
Lung Cancer
, vol.23
, pp. 143-152
-
-
Fu, X.L.1
Zhu, X.Z.2
Shi, D.R.3
-
18
-
-
0032959632
-
A biologic risk model for stage I lung cancer: Immunohistochemical analysis of 408 patients with the use of ten molecular markers
-
T.A. D'Amico, M. Massey, J.E. Herndon II A biologic risk model for stage I lung cancer Immunohistochemical analysis of 408 patients with the use of ten molecular markers J Thorac Cardiovasc Surg 117 1999 736 743
-
(1999)
J Thorac Cardiovasc Surg
, vol.117
, pp. 736-743
-
-
D'Amico, T.A.1
Massey, M.2
Herndon II, J.E.3
-
19
-
-
18744434862
-
Epidermal growth factor receptor expression correlates with poor prognosis in non-small cell lung cancer patients with p53 overexpression
-
Y. Ohsaki, S. Tanno, Y. Fujita Epidermal growth factor receptor expression correlates with poor prognosis in non-small cell lung cancer patients with p53 overexpression Oncol Rep 7 2000 603 607
-
(2000)
Oncol Rep
, vol.7
, pp. 603-607
-
-
Ohsaki, Y.1
Tanno, S.2
Fujita, Y.3
-
20
-
-
0034042621
-
Matrix metalloproteinase 9 and the epidermal growth factor signal pathway in operable non-small cell lung cancer
-
G. Cox, J.L. Jones, K.J. O'Byrne Matrix metalloproteinase 9 and the epidermal growth factor signal pathway in operable non-small cell lung cancer Clin Cancer Res 6 2000 2349 2355
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2349-2355
-
-
Cox, G.1
Jones, J.L.2
O'Byrne, K.J.3
-
21
-
-
0035658821
-
Immunohistochemical analysis of epidermal growth factor receptor family members in stage I non-small cell lung cancer
-
W.W. Lai, F.F. Chen, M.H. Wu Immunohistochemical analysis of epidermal growth factor receptor family members in stage I non-small cell lung cancer Ann Thorac Surg 72 2001 1868 1876
-
(2001)
Ann Thorac Surg
, vol.72
, pp. 1868-1876
-
-
Lai, W.W.1
Chen, F.F.2
Wu, M.H.3
-
22
-
-
0842305848
-
Phosphorylation, but not overexpression, of epidermal growth factor receptor is associated with poor prognosis of non-small cell lung cancer patients
-
T. Kanematsu, S. Yano, H. Uehara Phosphorylation, but not overexpression, of epidermal growth factor receptor is associated with poor prognosis of non-small cell lung cancer patients Oncol Res 13 2003 289 298
-
(2003)
Oncol Res
, vol.13
, pp. 289-298
-
-
Kanematsu, T.1
Yano, S.2
Uehara, H.3
-
23
-
-
0142119289
-
Epidermal growth factor receptor in non-small-cell lung carcinomas: Correlation between gene copy number and protein expression and impact on prognosis
-
F.R. Hirsch, M. Varella-Garcia, P.A. Bunn Jr Epidermal growth factor receptor in non-small-cell lung carcinomas Correlation between gene copy number and protein expression and impact on prognosis J Clin Oncol 21 2003 3798 3807
-
(2003)
J Clin Oncol
, vol.21
, pp. 3798-3807
-
-
Hirsch, F.R.1
Varella-Garcia, M.2
Bunn Jr., P.A.3
-
24
-
-
1642453746
-
Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage I non-small cell lung cancer
-
A. Onn, A.M. Correa, M. Gilcrease Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage I non-small cell lung cancer Clin Cancer Res 10 2004 136 143
-
(2004)
Clin Cancer Res
, vol.10
, pp. 136-143
-
-
Onn, A.1
Correa, A.M.2
Gilcrease, M.3
-
25
-
-
0032928459
-
Amplification and overexpression of the cyclin D1 and epidermal growth factor receptor genes in non-small-cell lung cancer
-
P.T. Reissmann, H. Koga, R.A. Figlin Amplification and overexpression of the cyclin D1 and epidermal growth factor receptor genes in non-small-cell lung cancer J Cancer Res Clin Oncol 125 1999 61 70
-
(1999)
J Cancer Res Clin Oncol
, vol.125
, pp. 61-70
-
-
Reissmann, P.T.1
Koga, H.2
Figlin, R.A.3
-
26
-
-
18644377457
-
The role of EGF-R expression on patient survival in lung cancer: A systematic review with meta-analysis
-
A.P. Meert, B. Martin, P. Delmotte The role of EGF-R expression on patient survival in lung cancer A systematic review with meta-analysis Eur Respir J 20 2002 975 981
-
(2002)
Eur Respir J
, vol.20
, pp. 975-981
-
-
Meert, A.P.1
Martin, B.2
Delmotte, P.3
-
27
-
-
0034954124
-
The type III epidermal growth factor receptor mutation
-
M.W. Pedersen, M. Meltorn, L. Damstrup The type III epidermal growth factor receptor mutation Ann Oncol 12 2001 745 760
-
(2001)
Ann Oncol
, vol.12
, pp. 745-760
-
-
Pedersen, M.W.1
Meltorn, M.2
Damstrup, L.3
-
28
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness fo non-small-cell lung cancer to gefitinib
-
T.J. Lynch, D.W. Bell, R. Sordella Activating mutations in the epidermal growth factor receptor underlying responsiveness fo non-small-cell lung cancer to gefitinib N Engl J Med 350 2004 2129 2139
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
29
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
J.G. Paez, P.A. Janne, J.C. Lee EGFR mutations in lung cancer Correlation with clinical response to gefitinib therapy Science 304 2004 1497 1500
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
30
-
-
0041629450
-
Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
-
J. Mendelsohn, J. Baselga Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer J Clin Oncol 21 2003 2787 2799
-
(2003)
J Clin Oncol
, vol.21
, pp. 2787-2799
-
-
Mendelsohn, J.1
Baselga, J.2
-
31
-
-
0036124415
-
Epidermal growth factor receptors as a target for cancer treatment: The emerging role of IMC-C225 in the treatment of lung and head and neck cancers
-
R.S. Herbst, C.J. Langer Epidermal growth factor receptors as a target for cancer treatment The emerging role of IMC-C225 in the treatment of lung and head and neck cancers Semin Oncol 29 2002 27 36
-
(2002)
Semin Oncol
, vol.29
, pp. 27-36
-
-
Herbst, R.S.1
Langer, C.J.2
-
32
-
-
0038816710
-
Phase IB/IIIA study of anti-epidermal growth factor receptor antibody, cetuximab, in combination with gemcitabine/carboplatin in patients with advanced stage IV non-small cell lung cancer
-
F. Robert, G. Blumenschein, K. Dicke Phase IB/IIIA study of anti-epidermal growth factor receptor antibody, cetuximab, in combination with gemcitabine/carboplatin in patients with advanced stage IV non-small cell lung cancer Proc Am Soc Clin Oncol 22 2003 643 (abstr)
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 643
-
-
Robert, F.1
Blumenschein, G.2
Dicke, K.3
-
33
-
-
0038140036
-
A multicenter phase I/II study of anti-epidermal growth factor receptor antibody, cetuximab, in combination with paclitaxel and carboplatin in patients with IV non-small cell lung cancer
-
K. Kelly, N. Hanna, A. Rosenberg A multicenter phase I/II study of anti-epidermal growth factor receptor antibody, cetuximab, in combination with paclitaxel and carboplatin in patients with IV non-small cell lung cancer Proc Am Soc Clin Oncol 22 2003 644 (abstr)
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 644
-
-
Kelly, K.1
Hanna, N.2
Rosenberg, A.3
-
34
-
-
33751580192
-
A phase II study of cetuximab, an epidermal growth factor receptor (EGFR) blocking antibody, in combination with docetaxel in chemotherapy refractory/resistant patients with advanced non-small cell lung cancer: Final report
-
E. Kim, A. Mauer, H. Tran A phase II study of cetuximab, an epidermal growth factor receptor (EGFR) blocking antibody, in combination with docetaxel in chemotherapy refractory/resistant patients with advanced non-small cell lung cancer Final report Proc Am Soc Clin Oncol 22 2003 642 (abstr)
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 642
-
-
Kim, E.1
Mauer, A.2
Tran, H.3
-
35
-
-
0038140033
-
Cetuximab (Erbitux) in combination with cisplatin/vinorelbine vs cisplatin/vinorelbine alone in the first-line treatment of patients with epidermal growth factor receptor-expressing advanced non-small cell lung cancer
-
U. Gatzemeier, R. Rosell, R. Ramlau Cetuximab (Erbitux) in combination with cisplatin/vinorelbine vs cisplatin/vinorelbine alone in the first-line treatment of patients with epidermal growth factor receptor-expressing advanced non-small cell lung cancer Proc Am Soc Clin Oncol 22 2003 642 (abstr)
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 642
-
-
Gatzemeier, U.1
Rosell, R.2
Ramlau, R.3
-
36
-
-
4444377694
-
Randomized phase II study of cetuximab in combination with cisplatin (C) and vinorelbine (V) vs. CV alone in the first-line treatment of patients (pts) with epidermal growth factor receptor (EGFR)-expressing advanced non-small-cell lung cancer (NSCLC)
-
R. Rosell, C. Daniel, R. Ramlau Randomized phase II study of cetuximab in combination with cisplatin (C) and vinorelbine (V) vs. CV alone in the first-line treatment of patients (pts) with epidermal growth factor receptor (EGFR)-expressing advanced non-small-cell lung cancer (NSCLC) Proc Am Soc Clin Oncol 23 2004 618a
-
(2004)
Proc Am Soc Clin Oncol
, vol.23
-
-
Rosell, R.1
Daniel, C.2
Ramlau, R.3
-
37
-
-
0036368423
-
ZD1839 (Iressa) in non-small cell lung cancer
-
R.S. Herbst, M.S. Kies ZD1839 (Iressa) in non-small cell lung cancer Oncologist 7 suppl 4 2002 9 15
-
(2002)
Oncologist
, vol.7
, Issue.4 SUPPL.
, pp. 9-15
-
-
Herbst, R.S.1
Kies, M.S.2
-
38
-
-
0038343121
-
Erlotinib (Tarceva): An update on the clinical trial program
-
R.S. Herbst Erlotinib (Tarceva) An update on the clinical trial program Semin Oncol 30 suppl 7 2003 34 46
-
(2003)
Semin Oncol
, vol.30
, Issue.7 SUPPL.
, pp. 34-46
-
-
Herbst, R.S.1
-
39
-
-
0012381722
-
Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer
-
M. Fukuoka, S. Yano, G. Giaccone Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer J Clin Oncol 21 2003 2237 2246
-
(2003)
J Clin Oncol
, vol.21
, pp. 2237-2246
-
-
Fukuoka, M.1
Yano, S.2
Giaccone, G.3
-
40
-
-
0142055937
-
Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
-
M.G. Kris, R.B. Natale, R.S. Herbst Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer A randomized trial JAMA 290 2003 2149 2158
-
(2003)
JAMA
, vol.290
, pp. 2149-2158
-
-
Kris, M.G.1
Natale, R.B.2
Herbst, R.S.3
-
41
-
-
0038501053
-
Targeting epidermal growth factor receptor-Are we missing the mark?
-
J.E. Dancey, B. Freidlin Targeting epidermal growth factor receptor-Are we missing the mark? Lancet 362 2003 62 64
-
(2003)
Lancet
, vol.362
, pp. 62-64
-
-
Dancey, J.E.1
Freidlin, B.2
-
42
-
-
1542503746
-
Gefitinib (ZD1839) in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: A phase III trial (INTACT 1)
-
G. Giaccone, R.S. Herbst, C. Manegold Gefitinib (ZD1839) in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer A phase III trial (INTACT 1) J Clin Oncol 22 2004 777 784
-
(2004)
J Clin Oncol
, vol.22
, pp. 777-784
-
-
Giaccone, G.1
Herbst, R.S.2
Manegold, C.3
-
43
-
-
1542713370
-
Gefitinib (ZD1839) in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: A phase III trial (INTACT 2)
-
R.S. Herbst, G. Giaccone, J.H. Schiller Gefitinib (ZD1839) in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer A phase III trial (INTACT 2) J Clin Oncol 22 2004 785 794
-
(2004)
J Clin Oncol
, vol.22
, pp. 785-794
-
-
Herbst, R.S.1
Giaccone, G.2
Schiller, J.H.3
-
44
-
-
4444238981
-
Results of a phase III trial of erlotinib (OSI-774) combined with cisplatin and gemcitabine (GC) chemotherapy in advanced non-small cell lung cancer
-
U. Gatzemeier, A. Pluzanska, A. Szczesna Results of a phase III trial of erlotinib (OSI-774) combined with cisplatin and gemcitabine (GC) chemotherapy in advanced non-small cell lung cancer Proc Am Soc Clin Oncol 22 2004 7010
-
(2004)
Proc Am Soc Clin Oncol
, vol.22
, pp. 7010
-
-
Gatzemeier, U.1
Pluzanska, A.2
Szczesna, A.3
-
45
-
-
11344272935
-
TRIBUTE-A phase III trial of erlotinib HCl (OSI-774) combined with carboplatin and paclitaxel (CP) chemotherapy in advanced non-small cell lung cancer
-
R.S. Herbst, D. Drager, R. Herman TRIBUTE-A phase III trial of erlotinib HCl (OSI-774) combined with carboplatin and paclitaxel (CP) chemotherapy in advanced non-small cell lung cancer Proc Am Soc Clin Oncol 22 2004 7011
-
(2004)
Proc Am Soc Clin Oncol
, vol.22
, pp. 7011
-
-
Herbst, R.S.1
Drager, D.2
Herman, R.3
-
46
-
-
5644303684
-
A randomized placebo-controlled trial of erlotinib in patients with non-small cell lung cancer (NSCLC) following failure of 1st line or 2nd line chemotherapy. a National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) trial
-
F.A. Shepherd, J. Pereira, T.E. Ciuleanu A randomized placebo-controlled trial of erlotinib in patients with non-small cell lung cancer (NSCLC) following failure of 1st line or 2nd line chemotherapy. A National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) trial J Clin Oncol 22 2004 145
-
(2004)
J Clin Oncol
, vol.22
, pp. 145
-
-
Shepherd, F.A.1
Pereira, J.2
Ciuleanu, T.E.3
-
47
-
-
17844390172
-
Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: Current knowledge and future directions
-
W. Pao, V.A. Miller Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer Current knowledge and future directions J Clin Oncol 23 2005 2268 2556
-
(2005)
J Clin Oncol
, vol.23
, pp. 2268-2556
-
-
Pao, W.1
Miller, V.A.2
-
48
-
-
20044364940
-
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
-
H. Shigematsu Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers J Natl Cancer Inst 97 2005 339 346
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 339-346
-
-
Shigematsu, H.1
-
49
-
-
0033118889
-
Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers
-
M. Pegram, S. Hsu, G. Lewis Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers Oncogene 18 1999 2241 2251
-
(1999)
Oncogene
, vol.18
, pp. 2241-2251
-
-
Pegram, M.1
Hsu, S.2
Lewis, G.3
-
50
-
-
0345012211
-
Trastuzumab in combination with paclitaxel/carboplatin advanced non-small cell lung cancer: Final report of ECOG 2598
-
J. Schiller, C.J. Langer, A. Thor Trastuzumab in combination with paclitaxel/carboplatin advanced non-small cell lung cancer Final report of ECOG 2598 Proc Am Soc Clin Oncol 22 2003 648 (abstr)
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 648
-
-
Schiller, J.1
Langer, C.J.2
Thor, A.3
-
51
-
-
0942287963
-
Randomized phase II trial of gemcitabine-cisplatin with or without trastuzumab in HER2-positive non-small-cell lung cancer
-
U. Gatzemeier, G. Groth, C. Butts Randomized phase II trial of gemcitabine-cisplatin with or without trastuzumab in HER2-positive non-small-cell lung cancer Ann Oncol 15 2004 19 27
-
(2004)
Ann Oncol
, vol.15
, pp. 19-27
-
-
Gatzemeier, U.1
Groth, G.2
Butts, C.3
-
52
-
-
0035985170
-
Non-small cell lung cancer clinical trials with trastuzumab: Their foundation and preliminary results
-
R.G. Zinner, J. Kim, R.S. Herbst Non-small cell lung cancer clinical trials with trastuzumab their foundation and preliminary results Lung Cancer 37 2002 17 27
-
(2002)
Lung Cancer
, vol.37
, pp. 17-27
-
-
Zinner, R.G.1
Kim, J.2
Herbst, R.S.3
-
53
-
-
0032855959
-
K-ras oncogene mutation as a prognostic marker in non-small cell lung cancer: A combined analysis of 881 cases
-
M. Huncharek, J. Muscat, J.F. Geschwind K-ras oncogene mutation as a prognostic marker in non-small cell lung cancer A combined analysis of 881 cases Carcinogenesis 20 1999 1507 1510
-
(1999)
Carcinogenesis
, vol.20
, pp. 1507-1510
-
-
Huncharek, M.1
Muscat, J.2
Geschwind, J.F.3
-
54
-
-
12444326918
-
Ras signaling and apoptosis
-
J. Downward Ras signaling and apoptosis Curr Opin Genet Dev 8 1998 9 54
-
(1998)
Curr Opin Genet Dev
, vol.8
, pp. 9-54
-
-
Downward, J.1
-
55
-
-
0037674454
-
An overview of farnesyltransferase inhibitors and their role in lung cancer therapy
-
A.A. Adjei An overview of farnesyltransferase inhibitors and their role in lung cancer therapy Lung Cancer 41 2003 55 62
-
(2003)
Lung Cancer
, vol.41
, pp. 55-62
-
-
Adjei, A.A.1
-
56
-
-
20644442851
-
-
Web page accessed 2/5/04: http://www.schering-plough.com/schering-plough/ news/release.jsp?releaseID=492402
-
-
-
-
57
-
-
0035819527
-
Development of matrix metalloproteinase inhibitors in cancer therapy
-
M. Hidalgo, S.G. Eckhardt Development of matrix metalloproteinase inhibitors in cancer therapy J Natl Cancer Inst 93 2001 178 193
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 178-193
-
-
Hidalgo, M.1
Eckhardt, S.G.2
-
58
-
-
0036809005
-
Pretreatment serum levels of matrix metalloproteinase-9 and vascular endothelial growth factor in non-small-cell lung cancer
-
E. Laack, A. Kohler, C. Kugler Pretreatment serum levels of matrix metalloproteinase-9 and vascular endothelial growth factor in non-small-cell lung cancer Ann Oncol 13 2002 1550 1557
-
(2002)
Ann Oncol
, vol.13
, pp. 1550-1557
-
-
Laack, E.1
Kohler, A.2
Kugler, C.3
-
59
-
-
0001185393
-
Phase III study of the matrix metalloprotease (MMP) inhibitor prinomastat in patients having advanced non-small cell lung cancer
-
M. Smylie, R. Mercier, D. Aboulafia Phase III study of the matrix metalloprotease (MMP) inhibitor prinomastat in patients having advanced non-small cell lung cancer Proc Am Soc Clin Oncol 20 2001 307 (abstr)
-
(2001)
Proc Am Soc Clin Oncol
, vol.20
, pp. 307
-
-
Smylie, M.1
Mercier, R.2
Aboulafia, D.3
-
60
-
-
0003266302
-
Phase III study of the matrix metalloprotease inhibitor prinomastat in combination with gemcitabine and cisplatin in non-small cell lung cancer
-
D. Bissett, J. Pawel, R. Mercier Phase III study of the matrix metalloprotease inhibitor prinomastat in combination with gemcitabine and cisplatin in non-small cell lung cancer Proc Am Soc Clin Oncol 21 2002 296 (abstr)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
, pp. 296
-
-
Bissett, D.1
Pawel, J.2
Mercier, R.3
-
61
-
-
0011758420
-
Phase I/II trials on the safety, tolerability and efficacy of Æ-941 (Neovastat) in patients with solid tumors
-
B. Franqois, P. Champagne, W. Evans Phase I/II trials on the safety, tolerability and efficacy of Æ-941 (Neovastat) in patients with solid tumors Proc Am Soc Clin Oncol 20 2001 277 (abstr)
-
(2001)
Proc Am Soc Clin Oncol
, vol.20
, pp. 277
-
-
Franqois, B.1
Champagne, P.2
Evans, W.3
-
62
-
-
17644388904
-
Randomized phase II-III study of matrix metalloproteinase inhibitor (MMPI) BMS-275291 in combination with paclitaxel (P) and carboplatin (C) in advanced non-small cell lung cancer (NSCLC): NCIC-CTG BR.18
-
N.B. Leighl, F. Shepherd, L. Pazares Randomized phase II-III study of matrix metalloproteinase inhibitor (MMPI) BMS-275291 in combination with paclitaxel (P) and carboplatin (C) in advanced non-small cell lung cancer (NSCLC) NCIC-CTG BR.18 J Clin Oncol 22 suppl 2004 (abstr)
-
(2004)
J Clin Oncol
, vol.22
, Issue.SUPPL.
-
-
Leighl, N.B.1
Shepherd, F.2
Pazares, L.3
-
64
-
-
0000262572
-
Phase I/II trial of ISIS 3521, an antisense inhibitor of PKC-alpha, with carboplatin and paclitaxel in non-small cell lung cancer
-
A. Yuen, R. Advani, G. Fisher Phase I/II trial of ISIS 3521, an antisense inhibitor of PKC-alpha, with carboplatin and paclitaxel in non-small cell lung cancer Proc Am Soc Clin Oncol 19 2001 167 (abstr)
-
(2001)
Proc Am Soc Clin Oncol
, vol.19
, pp. 167
-
-
Yuen, A.1
Advani, R.2
Fisher, G.3
-
65
-
-
0009682705
-
Phase I/II trial of ISIS 3521/LY900003, an antisense inhibitor of PKC-alpha with cisplatin and gemcitabine in advanced non-small cell lung cancer
-
P. Ritch, R. Belt, S. George Phase I/II trial of ISIS 3521/LY900003, an antisense inhibitor of PKC-alpha with cisplatin and gemcitabine in advanced non-small cell lung cancer Proc Am Soc Clin Oncol 21 2002 1233 (abstr)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
, pp. 1233
-
-
Ritch, P.1
Belt, R.2
George, S.3
-
66
-
-
0242455819
-
A. Randomized phase III trial of chemotherapy and antisense oligonucleotide LY900003 (ISIS 3521) in patients with advanced NSCLC: Initial report
-
T.J. Lynch, R. Raju, M. Lind A. Randomized phase III trial of chemotherapy and antisense oligonucleotide LY900003 (ISIS 3521) in patients with advanced NSCLC: Initial report Proc Am Soc Clin Oncol 22 2003 623 (abstr)
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 623
-
-
Lynch, T.J.1
Raju, R.2
Lind, M.3
-
67
-
-
0028419153
-
The retinoid signaling pathway: Molecular and genetic analyses
-
P. Chambon The retinoid signaling pathway molecular and genetic analyses Semin Cell Biol 5 1994 115 125
-
(1994)
Semin Cell Biol
, vol.5
, pp. 115-125
-
-
Chambon, P.1
-
68
-
-
0035906224
-
Randomized phase III intergroup trial of isotretinoin to prevent second primary tumors in stage I non-small-cell lung cancer
-
S.M. Lippman, J.J. Lee, D.D. Karp Randomized phase III intergroup trial of isotretinoin to prevent second primary tumors in stage I non-small-cell lung cancer J Natl Cancer Inst 93 2001 605 618
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 605-618
-
-
Lippman, S.M.1
Lee, J.J.2
Karp, D.D.3
-
69
-
-
0035873816
-
Multi-institutional phase I/II trial of oral bexarotene in combination with cisplatin and vinorelbine in previously untreated patients with advanced non-small-cell lung cancer
-
F.R. Khuri, J.R. Rigas, R.A. Figlin Multi-institutional phase I/II trial of oral bexarotene in combination with cisplatin and vinorelbine in previously untreated patients with advanced non-small-cell lung cancer J Clin Oncol 19 2001 2626 2637
-
(2001)
J Clin Oncol
, vol.19
, pp. 2626-2637
-
-
Khuri, F.R.1
Rigas, J.R.2
Figlin, R.A.3
-
70
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
J. Folkman Tumor angiogenesis Therapeutic implications N Engl J Med 285 1971 1182 1186
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
71
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
G. Bergers, L.E. Benjamin Tumorigenesis and the angiogenic switch Nat Rev 3 2003 401 410
-
(2003)
Nat Rev
, vol.3
, pp. 401-410
-
-
Bergers, G.1
Benjamin, L.E.2
-
72
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
J. Folkman Angiogenesis in cancer, vascular, rheumatoid and other disease Nat Med 1 1995 27 31
-
(1995)
Nat Med
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
73
-
-
0023039225
-
A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines
-
D.R. Senger, C.A. Perruzzi, J. Feder A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines Cancer Res 46 1986 5629 5632
-
(1986)
Cancer Res
, vol.46
, pp. 5629-5632
-
-
Senger, D.R.1
Perruzzi, C.A.2
Feder, J.3
-
74
-
-
0029738062
-
Significance of vascular endothelial growth factor messenger RNA expression in primary lung cancer
-
Y. Ohta, Y. Endo, M. Tanaka Significance of vascular endothelial growth factor messenger RNA expression in primary lung cancer Clin Cancer Res 2 1996 1411 1416
-
(1996)
Clin Cancer Res
, vol.2
, pp. 1411-1416
-
-
Ohta, Y.1
Endo, Y.2
Tanaka, M.3
-
75
-
-
1842328560
-
Prognostic value of vascular endothelial growth factor and its receptor Flt-1 in squamous cell lung cancer
-
M. Volm, R. Koomagi, J. Mattern Prognostic value of vascular endothelial growth factor and its receptor Flt-1 in squamous cell lung cancer Int J Cancer 74 1997 64 68
-
(1997)
Int J Cancer
, vol.74
, pp. 64-68
-
-
Volm, M.1
Koomagi, R.2
Mattern, J.3
-
76
-
-
0031966682
-
Vascular endothelial growth factor expression in non-small-cell lung cancer: Prognostic significance in squamous cell carcinoma
-
H. Imoto, T. Osaki, S. Taga Vascular endothelial growth factor expression in non-small-cell lung cancer Prognostic significance in squamous cell carcinoma J Thorac Cardiovasc Surg 115 1998 1007 1014
-
(1998)
J Thorac Cardiovasc Surg
, vol.115
, pp. 1007-1014
-
-
Imoto, H.1
Osaki, T.2
Taga, S.3
-
77
-
-
0031779403
-
Tumor angiogenesis and vascular endothelial growth factor expression in stage I lung adenocarcinoma
-
T. Shibusa, N. Shijubo, S. Abe Tumor angiogenesis and vascular endothelial growth factor expression in stage I lung adenocarcinoma Clin Cancer Res 4 1998 1483 1487
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1483-1487
-
-
Shibusa, T.1
Shijubo, N.2
Abe, S.3
-
78
-
-
17444378271
-
Vascular endothelial growth factor, wild-type p53, and angiogenesis in early operable non-small cell lung cancer
-
A. Giatromanolaki, M.I. Koukourakis, S. Kakolyris Vascular endothelial growth factor, wild-type p53, and angiogenesis in early operable non-small cell lung cancer Clin Cancer Res 4 1998 3017 3024
-
(1998)
Clin Cancer Res
, vol.4
, pp. 3017-3024
-
-
Giatromanolaki, A.1
Koukourakis, M.I.2
Kakolyris, S.3
-
79
-
-
0032055269
-
Bcl2 and p53 regulate vascular endothelial growth factor (VEGF)-mediated angiogenesis in non-small cell lung carcinoma
-
G. Fontanini, L. Boldrini, S. Vignati Bcl2 and p53 regulate vascular endothelial growth factor (VEGF)-mediated angiogenesis in non-small cell lung carcinoma Eur J Cancer 34 1998 718 723
-
(1998)
Eur J Cancer
, vol.34
, pp. 718-723
-
-
Fontanini, G.1
Boldrini, L.2
Vignati, S.3
-
80
-
-
0032762668
-
Immunohistochemical study on tumor angiogenic factors in non-small cell lung cancer
-
H. Aikawa, H. Takahashi, S. Fujimura Immunohistochemical study on tumor angiogenic factors in non-small cell lung cancer Anticancer Res 19 1999 4305 4309
-
(1999)
Anticancer Res
, vol.19
, pp. 4305-4309
-
-
Aikawa, H.1
Takahashi, H.2
Fujimura, S.3
-
81
-
-
0344937998
-
PD-ECGF, bFGF, and VEGF expression in non-small cell lung carcinomas and their association with lymph node metastasis
-
M. Volm, R. Koomagi, J. Mattern PD-ECGF, bFGF, and VEGF expression in non-small cell lung carcinomas and their association with lymph node metastasis Anticancer Res 19 1999 651 655
-
(1999)
Anticancer Res
, vol.19
, pp. 651-655
-
-
Volm, M.1
Koomagi, R.2
Mattern, J.3
-
82
-
-
0032742909
-
Tumor angiogenesis and recurrence in stage I non-small cell lung cancer
-
Y. Ohta, Y. Tomita, M. Oda Tumor angiogenesis and recurrence in stage I non-small cell lung cancer Ann Thorac Surg 68 1999 1034 1038
-
(1999)
Ann Thorac Surg
, vol.68
, pp. 1034-1038
-
-
Ohta, Y.1
Tomita, Y.2
Oda, M.3
-
83
-
-
0032826888
-
Vascular endothelial growth factor and osteopontin in stage I lung adenocarcinoma
-
N. Shijubo, T. Uede, S. Kon Vascular endothelial growth factor and osteopontin in stage I lung adenocarcinoma Am J Respir Crit Care Med 160 1999 1269 1273
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1269-1273
-
-
Shijubo, N.1
Uede, T.2
Kon, S.3
-
84
-
-
0034056981
-
Vascular endothelial growth factor expression and neovascularisation in non-small cell lung cancer
-
T. Yano, S. Tanikawa, T. Fujie Vascular endothelial growth factor expression and neovascularisation in non-small cell lung cancer Eur J Cancer 36 2000 601 609
-
(2000)
Eur J Cancer
, vol.36
, pp. 601-609
-
-
Yano, T.1
Tanikawa, S.2
Fujie, T.3
-
85
-
-
0035889962
-
The intratumoral expression of vascular endothelial growth factor and interleukin-8 associated with angiogenesis in non-small cell lung carcinoma patients
-
D. Masuya, C. Huang, D. Liu The intratumoral expression of vascular endothelial growth factor and interleukin-8 associated with angiogenesis in non-small cell lung carcinoma patients Cancer 92 2001 2628 2638
-
(2001)
Cancer
, vol.92
, pp. 2628-2638
-
-
Masuya, D.1
Huang, C.2
Liu, D.3
-
86
-
-
0035889901
-
Immune function, telomerase, and angiogenesis in patients with primary, operable non-small cell lung carcinoma: Tumor size and lymph node status remain the most important prognostic features
-
D. Toomey, G. Smyth, C. Condron Immune function, telomerase, and angiogenesis in patients with primary, operable non-small cell lung carcinoma Tumor size and lymph node status remain the most important prognostic features Cancer 92 2001 2648 2657
-
(2001)
Cancer
, vol.92
, pp. 2648-2657
-
-
Toomey, D.1
Smyth, G.2
Condron, C.3
-
87
-
-
0035142923
-
Prognostic value of vascularity and vascular endothelial growth factor expression in non-small cell lung cancer
-
R. Baillie, J. Carlile, N. Pendleton Prognostic value of vascularity and vascular endothelial growth factor expression in non-small cell lung cancer J Clin Pathol 54 2001 116 120
-
(2001)
J Clin Pathol
, vol.54
, pp. 116-120
-
-
Baillie, R.1
Carlile, J.2
Pendleton, N.3
-
88
-
-
0035155064
-
Vascular endothelial growth factor expression in stage I non-small cell lung cancer correlates with neoangiogenesis and a poor prognosis
-
H. Han, J.F. Silverman, T.S. Santucci Vascular endothelial growth factor expression in stage I non-small cell lung cancer correlates with neoangiogenesis and a poor prognosis Ann Surg Oncol 8 2001 72 79
-
(2001)
Ann Surg Oncol
, vol.8
, pp. 72-79
-
-
Han, H.1
Silverman, J.F.2
Santucci, T.S.3
-
89
-
-
0036805178
-
Prognostic significance of p53, Ki-67, VEGF and Glut-1 in resected stage I adenocarcinoma of the lung
-
K. Minami, Y. Saito, H. Imamura Prognostic significance of p53, Ki-67, VEGF and Glut-1 in resected stage I adenocarcinoma of the lung Lung Cancer 38 2002 51 57
-
(2002)
Lung Cancer
, vol.38
, pp. 51-57
-
-
Minami, K.1
Saito, Y.2
Imamura, H.3
-
92
-
-
0037106374
-
Mechanisms and future directions for angiogenesis-based cancer therapies
-
F.A. Scappaticci Mechanisms and future directions for angiogenesis-based cancer therapies J Clin Oncol 20 2002 3906 3927
-
(2002)
J Clin Oncol
, vol.20
, pp. 3906-3927
-
-
Scappaticci, F.A.1
-
93
-
-
0036653448
-
Angiogenesis inhibitors in lung cancer
-
E.S. Kim, R.S. Herbst Angiogenesis inhibitors in lung cancer Curr Oncol Rep 4 2002 325 333
-
(2002)
Curr Oncol Rep
, vol.4
, pp. 325-333
-
-
Kim, E.S.1
Herbst, R.S.2
-
94
-
-
0036121273
-
Angiogenesis inhibitors in clinical development for lung cancer
-
R.S. Herbst, M. Hidalgo, A.S. Pierson Angiogenesis inhibitors in clinical development for lung cancer Semin Oncol 29 suppl 4 2002 66 77
-
(2002)
Semin Oncol
, vol.29
, Issue.4 SUPPL.
, pp. 66-77
-
-
Herbst, R.S.1
Hidalgo, M.2
Pierson, A.S.3
-
95
-
-
0030856731
-
Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
-
L.G. Presta, H. Chen, S.J. O'Connor Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders Cancer Res 57 1997 4593 4599
-
(1997)
Cancer Res
, vol.57
, pp. 4593-4599
-
-
Presta, L.G.1
Chen, H.2
O'Connor, S.J.3
-
96
-
-
0035253586
-
Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: Pharmacologic and long-term safety data
-
K. Margolin, M.S. Gordon, E. Holmgren Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer Pharmacologic and long-term safety data J Clin Oncol 19 2001 851 856
-
(2001)
J Clin Oncol
, vol.19
, pp. 851-856
-
-
Margolin, K.1
Gordon, M.S.2
Holmgren, E.3
-
97
-
-
0035253739
-
Phase I safety and pharmachokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer
-
M.S. Gordon, K. Margolin, M. Talpaz Phase I safety and pharmachokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer J Clin Oncol 19 2001 843 850
-
(2001)
J Clin Oncol
, vol.19
, pp. 843-850
-
-
Gordon, M.S.1
Margolin, K.2
Talpaz, M.3
-
98
-
-
2942657615
-
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced metastatic non-small-cell lung cancer
-
D.H. Johnson, L. Fehrenbacher, W.F. Novotny Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced metastatic non-small-cell lung cancer J Clin Oncol 22 2004 2184 2191
-
(2004)
J Clin Oncol
, vol.22
, pp. 2184-2191
-
-
Johnson, D.H.1
Fehrenbacher, L.2
Novotny, W.F.3
-
99
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
H. Hurwitz, L. Fehrenbacher, W. Novotny Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer N Engl J Med 350 2004 2335 2342
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
100
-
-
0042343801
-
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
-
J.C. Yang, L. Haworth, R.M. Sherry A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer N Engl J Med 349 2003 427 434
-
(2003)
N Engl J Med
, vol.349
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
-
101
-
-
0032893263
-
SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types
-
T.A. Fong, L.K. Shawver, L. Sun SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types Cancer Res 59 1999 99 106
-
(1999)
Cancer Res
, vol.59
, pp. 99-106
-
-
Fong, T.A.1
Shawver, L.K.2
Sun, L.3
-
102
-
-
0037087585
-
Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SU5416 in patients with solid tumors
-
B.C. Kuenen, L. Rosen, E.F. Smit Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SU5416 in patients with solid tumors J Clin Oncol 15 2002 1657 1667
-
(2002)
J Clin Oncol
, vol.15
, pp. 1657-1667
-
-
Kuenen, B.C.1
Rosen, L.2
Smit, E.F.3
-
103
-
-
21244462047
-
ZD6474, a small molecule targeting VEGF and EGF receptor signaling, inhibits lung angiogenesis and metastasis and improves survival in an orthotopic model of non-small cell lung cancer
-
W. Wu, T. Isobe, S. Itasaka ZD6474, a small molecule targeting VEGF and EGF receptor signaling, inhibits lung angiogenesis and metastasis and improves survival in an orthotopic model of non-small cell lung cancer Proc Am Assoc Cancer Research 2004
-
(2004)
Proc Am Assoc Cancer Research
-
-
Wu, W.1
Isobe, T.2
Itasaka, S.3
-
104
-
-
0001410793
-
Clinical evaluation of ZD6474, an orally active inhibitor of VEGF signaling in patients with solid tumors
-
H. Hurwitz, S.N. Holden, S.G. Eckhardt Clinical evaluation of ZD6474, an orally active inhibitor of VEGF signaling in patients with solid tumors Proc Am Soc Clin Oncol 21 2002 82 (abstr)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
, pp. 82
-
-
Hurwitz, H.1
Holden, S.N.2
Eckhardt, S.G.3
-
105
-
-
0141542201
-
A phase I study of an oral VEGF receptor tyrosine kinase inhibitor ZD6474, in Japanese patients with solid tumors
-
H. Minami, H. Ebi, M. Tahara A phase I study of an oral VEGF receptor tyrosine kinase inhibitor ZD6474, in Japanese patients with solid tumors Proc Am Soc Clin Oncol 21 2003 194 (abstr)
-
(2003)
Proc Am Soc Clin Oncol
, vol.21
, pp. 194
-
-
Minami, H.1
Ebi, H.2
Tahara, M.3
-
106
-
-
0037115398
-
ZD6126: A novel vascular-targeting agent that causes selective destruction of tumor vasculature
-
P.D. Davis, G.J. Dougherty, D.C. Blakey ZD6126 A novel vascular-targeting agent that causes selective destruction of tumor vasculature Cancer Res 62 2002 7247 7253
-
(2002)
Cancer Res
, vol.62
, pp. 7247-7253
-
-
Davis, P.D.1
Dougherty, G.J.2
Blakey, D.C.3
-
107
-
-
0036644835
-
Activity of a new vascular targeting agent, ZD6126, in pulmonary metastases by human lung adenocarcinoma in nude mice
-
H. Goto, S. Yano, H. Zhang Activity of a new vascular targeting agent, ZD6126, in pulmonary metastases by human lung adenocarcinoma in nude mice Cancer Res 62 2002 3711 3715
-
(2002)
Cancer Res
, vol.62
, pp. 3711-3715
-
-
Goto, H.1
Yano, S.2
Zhang, H.3
-
108
-
-
0012692946
-
A dose-escalation study of the novel vascular-targeting agent, ZD6126, in patients with solid tumors
-
S.M. Gadgeel, P.M. LoRusso, A.J. Wozniak A dose-escalation study of the novel vascular-targeting agent, ZD6126, in patients with solid tumors Proc Am Soc Clin Oncol 21 2002 110a (abstr)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Gadgeel, S.M.1
Lorusso, P.M.2
Wozniak, A.J.3
-
109
-
-
0031454617
-
Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
-
M.S. O'Reilly, T. Boehm, Y. Shing Endostatin An endogenous inhibitor of angiogenesis and tumor growth Cell 88 1997 277 285
-
(1997)
Cell
, vol.88
, pp. 277-285
-
-
O'Reilly, M.S.1
Boehm, T.2
Shing, Y.3
-
110
-
-
0037106261
-
Phase I study of recombinant human endostatin in patients with advanced solid tumors
-
R.S. Herbst, K.R. Hess, H.T. Tran Phase I study of recombinant human endostatin in patients with advanced solid tumors J Clin Oncol 20 2002 3792 3803
-
(2002)
J Clin Oncol
, vol.20
, pp. 3792-3803
-
-
Herbst, R.S.1
Hess, K.R.2
Tran, H.T.3
-
111
-
-
20244381389
-
Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small-cell lung cancer
-
R.S. Herbst, D.H. Johnson, E. Mininberg Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small-cell lung cancer J Clin Oncol 23 2005 2544 2555
-
(2005)
J Clin Oncol
, vol.23
, pp. 2544-2555
-
-
Herbst, R.S.1
Johnson, D.H.2
Mininberg, E.3
-
112
-
-
17744418769
-
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
-
G. Steinbach, P.M. Lynch, R.K. Phillips The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis N Engl J Med 342 2000 1946 1952
-
(2000)
N Engl J Med
, vol.342
, pp. 1946-1952
-
-
Steinbach, G.1
Lynch, P.M.2
Phillips, R.K.3
-
113
-
-
0034026144
-
Cyclooxygenase-2 inhibitor induces apoptosis and enhances cytotoxicity of various anticancer agents in non-small cell lung cancer cell lines
-
T. Hida, K. Kozaki, H. Muramatsu Cyclooxygenase-2 inhibitor induces apoptosis and enhances cytotoxicity of various anticancer agents in non-small cell lung cancer cell lines Clin Cancer Res 6 2000 2006 2011
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2006-2011
-
-
Hida, T.1
Kozaki, K.2
Muramatsu, H.3
-
114
-
-
0000726512
-
Celecoxib (Celebrex), a selective COX-2 inhibitor, enhances the response to preoperative paclitaxel/carboplatin in early stage non-small cell lung cancer
-
N. Altorki, R. Keresztes, J. Port Celecoxib (Celebrex), a selective COX-2 inhibitor, enhances the response to preoperative paclitaxel/carboplatin in early stage non-small cell lung cancer Proc Am Soc Clin Oncol 21 2002 26 (abstr)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
, pp. 26
-
-
Altorki, N.1
Keresztes, R.2
Port, J.3
-
115
-
-
0000363736
-
Cyclooxygenase-2 (COX-2) inhibition + docetaxel (Txt) in recurrent non-small cell lung cancer (NSCLC): Preliminary results of a phase II trial (THO-0054)
-
I. Csiki, T. Dang, A. Gonzalez Cyclooxygenase-2 (COX-2) inhibition + docetaxel (Txt) in recurrent non-small cell lung cancer (NSCLC) Preliminary results of a phase II trial (THO-0054) Proc Am Soc Clin Oncol 21 2002 1187 (abstr)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
, pp. 1187
-
-
Csiki, I.1
Dang, T.2
Gonzalez, A.3
-
116
-
-
0035902141
-
The microenvironment of the tumor-host interface
-
L.A. Liotta, E.C. Kohn The microenvironment of the tumor-host interface Nature 411 2001 375 379
-
(2001)
Nature
, vol.411
, pp. 375-379
-
-
Liotta, L.A.1
Kohn, E.C.2
-
117
-
-
0036990103
-
The organ microenvironment and cancer metastasis
-
I.J. Fidler The organ microenvironment and cancer metastasis Differentiation 70 2002 498 505
-
(2002)
Differentiation
, vol.70
, pp. 498-505
-
-
Fidler, I.J.1
-
118
-
-
0036411742
-
Clinical trial design for target-based therapy
-
E. Fox, G.A. Curt, F.M. Balis Clinical trial design for target-based therapy Oncologist 7 2002 401 409
-
(2002)
Oncologist
, vol.7
, pp. 401-409
-
-
Fox, E.1
Curt, G.A.2
Balis, F.M.3
-
119
-
-
0347519171
-
For investigational targeted drugs, combination trials pose challenges
-
B. Goldman For investigational targeted drugs, combination trials pose challenges J Natl Cancer Inst 95 2003 1744 1746
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 1744-1746
-
-
Goldman, B.1
-
120
-
-
0036733591
-
Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas
-
C.H. Baker, D. Kedar, M.F. McCarty Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas Am J Pathol 161 2002 929 938
-
(2002)
Am J Pathol
, vol.161
, pp. 929-938
-
-
Baker, C.H.1
Kedar, D.2
McCarty, M.F.3
-
121
-
-
0034777482
-
Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer is correlated with survival
-
J. Brabender, K.D. Danenberg, R. Metzger Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer is correlated with survival Clin Cancer Res 7 2001 1850 1855
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1850-1855
-
-
Brabender, J.1
Danenberg, K.D.2
Metzger, R.3
-
122
-
-
0042298072
-
Phase I/II study of the recombinant humanized monoclonal anti-VEGF antibody bevacizumab and the EGFR-TK inhibitor erlotinib in patients with recurrent non-small cell lung cancer
-
E.D. Mininberg, R.S. Herbst, T. Henderson Phase I/II study of the recombinant humanized monoclonal anti-VEGF antibody bevacizumab and the EGFR-TK inhibitor erlotinib in patients with recurrent non-small cell lung cancer Proc Am Soc Clin Oncol 22 2003 627 (abstr)
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 627
-
-
Mininberg, E.D.1
Herbst, R.S.2
Henderson, T.3
-
123
-
-
0345060457
-
Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice
-
A. Onn, T. Isobe, S. Itasaka Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice Clin Cancer Res 9 2003 5532 5539
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5532-5539
-
-
Onn, A.1
Isobe, T.2
Itasaka, S.3
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