-
1
-
-
0037104968
-
Functional downregulation of P2X3 receptor subunit in rat sensory neurons reveals a significant role in chronic neuropathic and inflammatory pain
-
J. Barclay, S. Patel, G. Dorn, G. Wotherspoon, S. Moffatt, L. Eunson, S. Abdel'al, F. Natt, J. Hall, J. Winter, S. Bevan, W. Wishart, A. Fox, and P. Ganju Functional downregulation of P2X3 receptor subunit in rat sensory neurons reveals a significant role in chronic neuropathic and inflammatory pain J Neurosci 22 2002 8139 8147
-
(2002)
J Neurosci
, vol.22
, pp. 8139-8147
-
-
Barclay, J.1
Patel, S.2
Dorn, G.3
Wotherspoon, G.4
Moffatt, S.5
Eunson, L.6
Abdel'Al, S.7
Natt, F.8
Hall, J.9
Winter, J.10
Bevan, S.11
Wishart, W.12
Fox, A.13
Ganju, P.14
-
2
-
-
0028025001
-
New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor
-
A. Brake, M.J. Wagenbach, and D. Julius New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor Nature 371 1994 519 523
-
(1994)
Nature
, vol.371
, pp. 519-523
-
-
Brake, A.1
Wagenbach, M.J.2
Julius, D.3
-
3
-
-
0035313093
-
Purine-mediated signalling in pain and visceral perception
-
G. Burnstock Purine-mediated signalling in pain and visceral perception Trends Pharmacol Sci 22 2001 182 188
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 182-188
-
-
Burnstock, G.1
-
4
-
-
0021704654
-
Temperature preference of genetically obese (ob/ob) mice
-
H.J. Carlisle, and P.U. Dubuc Temperature preference of genetically obese (ob/ob) mice Physiol Behav 33 1984 899 902
-
(1984)
Physiol Behav
, vol.33
, pp. 899-902
-
-
Carlisle, H.J.1
Dubuc, P.U.2
-
5
-
-
0034646740
-
Impaired nociception and pain sensation in mice lacking the capsaicin receptor
-
M.J. Caterina, A. Leffler, A.B. Malmberg, W.J. Martin, J. Trafton, K.R. Petersen-Zeitz, M. Koltzenburg, A.I. Basbaum, and D. Julius Impaired nociception and pain sensation in mice lacking the capsaicin receptor Science 288 2000 306 313 [see comments]
-
(2000)
Science
, vol.288
, pp. 306-313
-
-
Caterina, M.J.1
Leffler, A.2
Malmberg, A.B.3
Martin, W.J.4
Trafton, J.5
Petersen-Zeitz, K.R.6
Koltzenburg, M.7
Basbaum, A.I.8
Julius, D.9
-
6
-
-
0029102288
-
A P2X purinoceptor expressed by a subset of sensory neurons
-
C.C. Chen, A.N. Akopian, L. Silvilotti, D. Colquhoun, G. Burnstock, and J.N. Wood A P2X purinoceptor expressed by a subset of sensory neurons Nature 377 1995 428 431
-
(1995)
Nature
, vol.377
, pp. 428-431
-
-
Chen, C.C.1
Akopian, A.N.2
Silvilotti, L.3
Colquhoun, D.4
Burnstock, G.5
Wood, J.N.6
-
7
-
-
0034718839
-
Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice
-
D.A. Cockayne, S.G. Hamilton, Q.M. Zhu, P.M. Dunn, Y. Zhong, S. Novakovic, A.B. Malmberg, G. Cain, A. Berson, L. Kassotakis, L. Hedley, W.G. Lachnit, G. Burnstock, S.B. McMahon, and A.P. Ford Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice Nature 407 2000 1011 1015
-
(2000)
Nature
, vol.407
, pp. 1011-1015
-
-
Cockayne, D.A.1
Hamilton, S.G.2
Zhu, Q.M.3
Dunn, P.M.4
Zhong, Y.5
Novakovic, S.6
Malmberg, A.B.7
Cain, G.8
Berson, A.9
Kassotakis, L.10
Hedley, L.11
Lachnit, W.G.12
Burnstock, G.13
McMahon, S.B.14
Ford, A.P.15
-
8
-
-
0030922667
-
Distinct ATP receptors on pain-sensing and stretch-sensing neurons
-
S.P. Cook, L. Vulchanova, K.M. Hargreaves, R. Elde, and E.W. McCleskey Distinct ATP receptors on pain-sensing and stretch-sensing neurons Nature 387 1997 505 508
-
(1997)
Nature
, vol.387
, pp. 505-508
-
-
Cook, S.P.1
Vulchanova, L.2
Hargreaves, K.M.3
Elde, R.4
McCleskey, E.W.5
-
9
-
-
0026759019
-
Behavioral temperature regulation during withdrawal from ethanol dependency in mice
-
L.I. Crawshaw, C.S. O'Connor, D.L. Hayteas, and J.C. Crabbe Behavioral temperature regulation during withdrawal from ethanol dependency in mice Ann NY Acad Sci 654 1992 428 430
-
(1992)
Ann NY Acad Sci
, vol.654
, pp. 428-430
-
-
Crawshaw, L.I.1
O'Connor, C.S.2
Hayteas, D.L.3
Crabbe, J.C.4
-
10
-
-
10344261343
-
SiRNA relieves chronic neuropathic pain
-
G. Dorn, S. Patel, G. Wotherspoon, M. Hemmings-Mieszczak, J. Barclay, F.J. Natt, P. Martin, S. Bevan, A. Fox, P. Ganju, W. Wishart, and J. Hall siRNA relieves chronic neuropathic pain Nucleic Acids Res 32 2004 e49
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 49
-
-
Dorn, G.1
Patel, S.2
Wotherspoon, G.3
Hemmings-Mieszczak, M.4
Barclay, J.5
Natt, F.J.6
Martin, P.7
Bevan, S.8
Fox, A.9
Ganju, P.10
Wishart, W.11
Hall, J.12
-
13
-
-
0021794102
-
Relationship between autonomic and behavioral thermoregulation in the mouse
-
C.J. Gordon Relationship between autonomic and behavioral thermoregulation in the mouse Physiol Behav 34 1985 687 690
-
(1985)
Physiol Behav
, vol.34
, pp. 687-690
-
-
Gordon, C.J.1
-
14
-
-
0034991820
-
Acute and delayed thermoregulatory response of mice exposed to brevetoxin
-
C.J. Gordon, K.L. Kimm-Brinson, B. Padnos, and J.S. Ramsdell Acute and delayed thermoregulatory response of mice exposed to brevetoxin Toxicon 39 2001 1367 1374
-
(2001)
Toxicon
, vol.39
, pp. 1367-1374
-
-
Gordon, C.J.1
Kimm-Brinson, K.L.2
Padnos, B.3
Ramsdell, J.S.4
-
16
-
-
0036703646
-
Heat-evoked activation of the ion channel, TRPV4
-
A.D. Guler, H. Lee, T. Iida, I. Shimizu, M. Tominaga, and M. Caterina Heat-evoked activation of the ion channel, TRPV4 J Neurosci 22 2002 6408 6414
-
(2002)
J Neurosci
, vol.22
, pp. 6408-6414
-
-
Guler, A.D.1
Lee, H.2
Iida, T.3
Shimizu, I.4
Tominaga, M.5
Caterina, M.6
-
17
-
-
0036711339
-
Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats
-
P. Honore, K. Kage, J. Mikusa, A.T. Watt, J.F. Johnston, J.R. Wyatt, C.R. Faltynek, M.F. Jarvis, and K. Lynch Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats Pain 99 2002 11 19
-
(2002)
Pain
, vol.99
, pp. 11-19
-
-
Honore, P.1
Kage, K.2
Mikusa, J.3
Watt, A.T.4
Johnston, J.F.5
Wyatt, J.R.6
Faltynek, C.R.7
Jarvis, M.F.8
Lynch, K.9
-
18
-
-
0037168683
-
A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat
-
M.F. Jarvis, E.C. Burgard, S. McGaraughty, P. Honore, K. Lynch, T.J. Brennan, A. Subieta, T. Van Biesen, J. Cartmell, B. Bianchi, W. Niforatos, K. Kage, H. Yu, J. Mikusa, C.T. Wismer, C.Z. Zhu, K. Chu, C.H. Lee, A.O. Stewart, J. Polakowski, and B.F. Cox A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat Proc Natl Acad Sci USA 99 2002 17179 17184
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 17179-17184
-
-
Jarvis, M.F.1
Burgard, E.C.2
McGaraughty, S.3
Honore, P.4
Lynch, K.5
Brennan, T.J.6
Subieta, A.7
Van Biesen, T.8
Cartmell, J.9
Bianchi, B.10
Niforatos, W.11
Kage, K.12
Yu, H.13
Mikusa, J.14
Wismer, C.T.15
Zhu, C.Z.16
Chu, K.17
Lee, C.H.18
Stewart, A.O.19
Polakowski, J.20
Cox, B.F.21
more..
-
19
-
-
0018735337
-
Thermotaxis in neonatal rat pups
-
I.B. Johanson Thermotaxis in neonatal rat pups Physiol Behav 23 1979 871 874
-
(1979)
Physiol Behav
, vol.23
, pp. 871-874
-
-
Johanson, I.B.1
-
20
-
-
0020420357
-
Thermoregulatory behavior in rat pups from birth to weaning
-
N. Kleitman, and E. Satinoff Thermoregulatory behavior in rat pups from birth to weaning Physiol Behav 29 1982 537 541
-
(1982)
Physiol Behav
, vol.29
, pp. 537-541
-
-
Kleitman, N.1
Satinoff, E.2
-
21
-
-
0037850063
-
Localization and function of ATP and GABAA receptors expressed by nociceptors and other postnatal sensory neurons in rat
-
C. Labrakakis, C.K. Tong, T. Weissman, C. Torsney, and A.B. MacDermott Localization and function of ATP and GABAA receptors expressed by nociceptors and other postnatal sensory neurons in rat J Physiol 549 2003 131 142
-
(2003)
J Physiol
, vol.549
, pp. 131-142
-
-
Labrakakis, C.1
Tong, C.K.2
Weissman, T.3
Torsney, C.4
MacDermott, A.B.5
-
22
-
-
13944255381
-
Altered thermal selection behavior in mice lacking transient receptor potential vanilloid 4
-
H. Lee, T. Iida, A. Mizuno, M. Suzuki, and M.J. Caterina Altered thermal selection behavior in mice lacking transient receptor potential vanilloid 4 J Neurosci 25 2005 1304 1310
-
(2005)
J Neurosci
, vol.25
, pp. 1304-1310
-
-
Lee, H.1
Iida, T.2
Mizuno, A.3
Suzuki, M.4
Caterina, M.J.5
-
24
-
-
0032217269
-
ATP P2x receptors and sensory synaptic transmission between primary afferent fibers and spinal dorsal horn neurons in rats
-
P. Li, A.A. Calejesan, and M. Zhuo ATP P2x receptors and sensory synaptic transmission between primary afferent fibers and spinal dorsal horn neurons in rats J Neurophysiol 80 1998 3356 3360
-
(1998)
J Neurophysiol
, vol.80
, pp. 3356-3360
-
-
Li, P.1
Calejesan, A.A.2
Zhuo, M.3
-
25
-
-
0141646406
-
A specific inhibitory pathway between substantia gelatinosa neurons receiving direct C-fiber input
-
Y. Lu, and E.R. Perl A specific inhibitory pathway between substantia gelatinosa neurons receiving direct C-fiber input J Neurosci 23 2003 8752 8758
-
(2003)
J Neurosci
, vol.23
, pp. 8752-8758
-
-
Lu, Y.1
Perl, E.R.2
-
26
-
-
0035878076
-
PKCgamma contributes to a subset of the NMDA-dependent spinal circuits that underlie injury-induced persistent pain
-
W.J. Martin, A.B. Malmberg, and A.I. Basbaum PKCgamma contributes to a subset of the NMDA-dependent spinal circuits that underlie injury-induced persistent pain J Neurosci 21 2001 5321 5327
-
(2001)
J Neurosci
, vol.21
, pp. 5321-5327
-
-
Martin, W.J.1
Malmberg, A.B.2
Basbaum, A.I.3
-
27
-
-
0347949526
-
Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration
-
S. McGaraughty, C.T. Wismer, C.Z. Zhu, J. Mikusa, P. Honore, K.L. Chu, C.H. Lee, C.R. Faltynek, and M.F. Jarvis Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration Br J Pharmacol 140 2003 1381 1388
-
(2003)
Br J Pharmacol
, vol.140
, pp. 1381-1388
-
-
McGaraughty, S.1
Wismer, C.T.2
Zhu, C.Z.3
Mikusa, J.4
Honore, P.5
Chu, K.L.6
Lee, C.H.7
Faltynek, C.R.8
Jarvis, M.F.9
-
28
-
-
0017344097
-
An analysis of response properties of spinal cord dorsal horn neurones to nonnoxious and noxious stimuli in the spinal rat
-
D. Menetrey, G.J. Giesler Jr, and J.M. Besson An analysis of response properties of spinal cord dorsal horn neurones to nonnoxious and noxious stimuli in the spinal rat Exp Brain Res 27 1977 15 33
-
(1977)
Exp Brain Res
, vol.27
, pp. 15-33
-
-
Menetrey, D.1
Giesler Jr., G.J.2
Besson, J.M.3
-
29
-
-
0033030271
-
Heritability of nociception I: Responses of 11 inbred mouse strains on 12 measures of nociception
-
J. Mogil, S.G. Wilson, K. Bon, S.E. Lee, K. Chung, P. Raber, J.O. Pieper, H.S. Hain, J.K. Belknap, L. Hubert, G.I. Elmer, J.M. Chung, and M. Devor Heritability of nociception I: Responses of 11 inbred mouse strains on 12 measures of nociception Pain 80 1999 67 82
-
(1999)
Pain
, vol.80
, pp. 67-82
-
-
Mogil, J.1
Wilson, S.G.2
Bon, K.3
Lee, S.E.4
Chung, K.5
Raber, P.6
Pieper, J.O.7
Hain, H.S.8
Belknap, J.K.9
Hubert, L.10
Elmer, G.I.11
Chung, J.M.12
Devor, M.13
-
30
-
-
0021711550
-
The cytoarchitectonic organization of the spinal cord in the rat. I. the lower thoracic and lumbosacral cord
-
C. Molander, Q. Xu, and G. Grant The cytoarchitectonic organization of the spinal cord in the rat. I. The lower thoracic and lumbosacral cord J Comp Neurol 230 1984 133 141
-
(1984)
J Comp Neurol
, vol.230
, pp. 133-141
-
-
Molander, C.1
Xu, Q.2
Grant, G.3
-
31
-
-
0037077041
-
A heat-sensitive TRP channel expressed in keratinocytes
-
A.M. Peier, A.J. Reeve, D.A. Andersson, A. Moqrich, T.J. Earley, A.C. Hergarden, G.M. Story, S. Colley, J.B. Hogenesch, P. McIntyre, S. Bevan, and A. Patapoutian A heat-sensitive TRP channel expressed in keratinocytes Science 296 2002 2046 2049
-
(2002)
Science
, vol.296
, pp. 2046-2049
-
-
Peier, A.M.1
Reeve, A.J.2
Andersson, D.A.3
Moqrich, A.4
Earley, T.J.5
Hergarden, A.C.6
Story, G.M.7
Colley, S.8
Hogenesch, J.B.9
McIntyre, P.10
Bevan, S.11
Patapoutian, A.12
-
32
-
-
0346218117
-
Pivotal role of nucleotide P2X2 receptor subunit of the ATP-gated ion channel mediating ventilatory responses to hypoxia
-
W. Rong, A.V. Gourine, D.A. Cockayne, Z. Xiang, A.P. Ford, K.M. Spyer, and G. Burnstock Pivotal role of nucleotide P2X2 receptor subunit of the ATP-gated ion channel mediating ventilatory responses to hypoxia J Neurosci 23 2003 11315 11321
-
(2003)
J Neurosci
, vol.23
, pp. 11315-11321
-
-
Rong, W.1
Gourine, A.V.2
Cockayne, D.A.3
Xiang, Z.4
Ford, A.P.5
Spyer, K.M.6
Burnstock, G.7
-
34
-
-
0034718892
-
Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors
-
V. Souslova, P. Cesare, Y. Ding, A.N. Akopian, L. Stanfa, R. Suzuki, K. Carpenter, A. Dickenson, S. Boyce, R. Hill, D. Nebenuis-Oosthuizen, A.J. Smith, E.J. Kidd, and J.N. Wood Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors Nature 407 2000 1015 1017
-
(2000)
Nature
, vol.407
, pp. 1015-1017
-
-
Souslova, V.1
Cesare, P.2
Ding, Y.3
Akopian, A.N.4
Stanfa, L.5
Suzuki, R.6
Carpenter, K.7
Dickenson, A.8
Boyce, S.9
Hill, R.10
Nebenuis-Oosthuizen, D.11
Smith, A.J.12
Kidd, E.J.13
Wood, J.N.14
-
35
-
-
0032726925
-
Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice
-
M. Tsuda, S. Ueno, and K. Inoue Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice Br J Pharmacol 128 1999 1497 1504
-
(1999)
Br J Pharmacol
, vol.128
, pp. 1497-1504
-
-
Tsuda, M.1
Ueno, S.2
Inoue, K.3
-
36
-
-
0034256565
-
Mechanical allodynia caused by intraplantar injection of P2X receptor agonist in rats: Involvement of heteromeric P2X2/3 receptor signaling in capsaicin-insensitive primary afferent neurons
-
M. Tsuda, S. Koizumi, A. Kita, Y. Shigemoto, S. Ueno, and K. Inoue Mechanical allodynia caused by intraplantar injection of P2X receptor agonist in rats: involvement of heteromeric P2X2/3 receptor signaling in capsaicin-insensitive primary afferent neurons J Neurosci 20 2000 RC90
-
(2000)
J Neurosci
, vol.20
, pp. 90
-
-
Tsuda, M.1
Koizumi, S.2
Kita, A.3
Shigemoto, Y.4
Ueno, S.5
Inoue, K.6
-
37
-
-
0031866948
-
Trinitrophenyl-substituted nucleotides are potent antagonists selective for P2X1, P2X3, and heteromeric P2X2/3 receptors
-
C. Virginio, G. Robertson, A. Surprenant, and R.A. North Trinitrophenyl-substituted nucleotides are potent antagonists selective for P2X1, P2X3, and heteromeric P2X2/3 receptors Mol Pharmacol 53 1998 969 973
-
(1998)
Mol Pharmacol
, vol.53
, pp. 969-973
-
-
Virginio, C.1
Robertson, G.2
Surprenant, A.3
North, R.A.4
-
38
-
-
0032217032
-
P2X3 is expressed by DRG neurons that terminate in inner lamina II
-
L. Vulchanova, M.S. Riedl, S.J. Shuster, L.S. Stone, K.M. Hargreaves, G. Buell, A. Surprenant, R.A. North, and R. Elde P2X3 is expressed by DRG neurons that terminate in inner lamina II Eur J Neurosci 10 1998 3470 3478
-
(1998)
Eur J Neurosci
, vol.10
, pp. 3470-3478
-
-
Vulchanova, L.1
Riedl, M.S.2
Shuster, S.J.3
Stone, L.S.4
Hargreaves, K.M.5
Buell, G.6
Surprenant, A.7
North, R.A.8
Elde, R.9
-
39
-
-
0034988626
-
Sensory processing in the deep spinal dorsal horn of neurokinin-1 receptor knockout mice
-
H.R. Weng, H. Mansikka, R. Winchurch, S.N. Raja, and P.M. Dougherty Sensory processing in the deep spinal dorsal horn of neurokinin-1 receptor knockout mice Anesthesiology 94 2001 1105 1112
-
(2001)
Anesthesiology
, vol.94
, pp. 1105-1112
-
-
Weng, H.R.1
Mansikka, H.2
Winchurch, R.3
Raja, S.N.4
Dougherty, P.M.5
-
40
-
-
0030276412
-
Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: Electrophysiological evidence
-
D.C. Yeomans, and H.K. Proudfit Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: electrophysiological evidence Pain 68 1996 141 150
-
(1996)
Pain
, vol.68
, pp. 141-150
-
-
Yeomans, D.C.1
Proudfit, H.K.2
-
41
-
-
0030275438
-
Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: Behavioral evidence
-
D.C. Yeomans, V. Pirec, and H.K. Proudfit Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: behavioral evidence Pain 68 1996 133 140
-
(1996)
Pain
, vol.68
, pp. 133-140
-
-
Yeomans, D.C.1
Pirec, V.2
Proudfit, H.K.3
-
43
-
-
0344305541
-
Transgenic mice possessing increased numbers of nociceptors do not exhibit increased behavioral sensitivity in models of inflammatory and neuropathic pain
-
M. Zwick, D.C. Molliver, J. Lindsay, C.A. Fairbanks, T. Sengoku, K.M. Albers, and B.M. Davis Transgenic mice possessing increased numbers of nociceptors do not exhibit increased behavioral sensitivity in models of inflammatory and neuropathic pain Pain 106 2003 491 500
-
(2003)
Pain
, vol.106
, pp. 491-500
-
-
Zwick, M.1
Molliver, D.C.2
Lindsay, J.3
Fairbanks, C.A.4
Sengoku, T.5
Albers, K.M.6
Davis, B.M.7
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