-
1
-
-
2642566893
-
Organizational challenges in clinical genomic research
-
Altshuler JS, Altshuler D: Organizational challenges in clinical genomic research. Nature 2004, 429:478-481.
-
(2004)
Nature
, vol.429
, pp. 478-481
-
-
Altshuler, J.S.1
Altshuler, D.2
-
2
-
-
20044386880
-
Highly multiplexed molecular inversion probe genotyping: Over 10,000 targeted SNPs genotyped in a single tube assay
-
Hardenbol P, Yu F, Belmont J, et al.: Highly multiplexed molecular inversion probe genotyping: over 10,000 targeted SNPs genotyped in a single tube assay. Genome Res 2005, 15:269-275.
-
(2005)
Genome Res.
, vol.15
, pp. 269-275
-
-
Hardenbol, P.1
Yu, F.2
Belmont, J.3
-
4
-
-
2142773942
-
The fine-scale structure of recombination rate variation in the human genome
-
McVean GA, Myers SR, Hunt S, et al.: The fine-scale structure of recombination rate variation in the human genome. Science 2004, 304:581-584.
-
(2004)
Science
, vol.304
, pp. 581-584
-
-
McVean, G.A.1
Myers, S.R.2
Hunt, S.3
-
5
-
-
13844313862
-
Whole-genome patterns of common DNA variation in three human populations
-
Hinds DA, Stuve LL, Nilsen GB, et al.: Whole-genome patterns of common DNA variation in three human populations. Science 2005, 307:1072-1079.
-
(2005)
Science
, vol.307
, pp. 1072-1079
-
-
Hinds, D.A.1
Stuve, L.L.2
Nilsen, G.B.3
-
6
-
-
0037234409
-
In silico quantitative trait locus map for atherosclerosis susceptibility in apolipoprotein E-deficient mice
-
Smith JD, James D, Dansky HM, et al.: In silico quantitative trait locus map for atherosclerosis susceptibility in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2003, 23:117-122.
-
(2003)
Arterioscler. Thromb. Vasc. Biol.
, vol.23
, pp. 117-122
-
-
Smith, J.D.1
James, D.2
Dansky, H.M.3
-
7
-
-
0032827782
-
The power of association studies to detect the contribution of candidate genetic loci to variation in complex traits
-
Long AD, Langley CH: The power of association studies to detect the contribution of candidate genetic loci to variation in complex traits. Genome Res 1999, 9:720-731.
-
(1999)
Genome Res.
, vol.9
, pp. 720-731
-
-
Long, A.D.1
Langley, C.H.2
-
8
-
-
0037356574
-
Mapping quantitative trait loci in the case of a spike in the phenotype distribution
-
Broman KW: Mapping quantitative trait loci in the case of a spike in the phenotype distribution. Genetics 2003, 163:1169-1175.
-
(2003)
Genetics
, vol.163
, pp. 1169-1175
-
-
Broman, K.W.1
-
9
-
-
85047682649
-
Review of assumptions and problems in the appropriate conceptualization of effect size
-
Grissom RJ, Kim JJ: Review of assumptions and problems in the appropriate conceptualization of effect size. Psychol Methods 2001, 6:135-146.
-
(2001)
Psychol. Methods
, vol.6
, pp. 135-146
-
-
Grissom, R.J.1
Kim, J.J.2
-
10
-
-
0034987323
-
The power to detect linkage disequilibrium with quantitative traits in selected samples
-
Abecasis GR, Cookson WO, Cardon LR: The power to detect linkage disequilibrium with quantitative traits in selected samples. Am J Hum Genet 2001, 68:1463-1474.
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 1463-1474
-
-
Abecasis, G.R.1
Cookson, W.O.2
Cardon, L.R.3
-
11
-
-
0742288585
-
The complex interplay among factors that influence allelic association
-
Zondervan KT, Cardon LR: The complex interplay among factors that influence allelic association. Nat Rev Genet 2004, 5:89-100.
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 89-100
-
-
Zondervan, K.T.1
Cardon, L.R.2
-
12
-
-
0035825219
-
Endophenotypes as quantitative risk factors for psychiatric disease: Rationale and study design
-
Almasy L, Blangero J: Endophenotypes as quantitative risk factors for psychiatric disease: rationale and study design. Am J Med Genet 2001, 105:42-44.
-
(2001)
Am. J. Med. Genet.
, vol.105
, pp. 42-44
-
-
Almasy, L.1
Blangero, J.2
-
13
-
-
0038823525
-
The endophenotype concept in psychiatry: Etymology and strategic intentions
-
Gottesman II, Gould TD: The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003, 160:636-645.
-
(2003)
Am. J. Psychiatry
, vol.160
, pp. 636-645
-
-
Gottesman, I.I.1
Gould, T.D.2
-
14
-
-
18344386779
-
Genome scans provide evidence for low-HDL-C loci on chromosomes 8q23, 16q24.1-24.2, and 20q13.11 in Finnish families
-
Soro A, Pajukanta P, Lilja HE, et al.: Genome scans provide evidence for low-HDL-C loci on chromosomes 8q23, 16q24.1-24.2, and 20q13.11 in Finnish families. Am J Hum Genet 2002, 70:1333-1340.
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 1333-1340
-
-
Soro, A.1
Pajukanta, P.2
Lilja, H.E.3
-
16
-
-
0036908801
-
Multiplex relative risk and estimation of the number of loci underlying an inherited disease
-
Schliekelman P, Slatkin M: Multiplex relative risk and estimation of the number of loci underlying an inherited disease. Am J Hum Genet 2002, 71:1369-1385.
-
(2002)
Am. J. Hum. Genet.
, vol.71
, pp. 1369-1385
-
-
Schliekelman, P.1
Slatkin, M.2
-
17
-
-
0025019555
-
Linkage strategies for genetically complex traits. I. Multilocus models
-
Risch N: Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet 1990, 46:222-228.
-
(1990)
Am. J. Hum. Genet.
, vol.46
, pp. 222-228
-
-
Risch, N.1
-
18
-
-
0029568046
-
Use of sibling risk ratios and components of genetic variance in the characterization of a simulated oligogenic disease
-
Almasy L, Tierney C, Risch N: Use of sibling risk ratios and components of genetic variance in the characterization of a simulated oligogenic disease. Genet Epidemiol 1995, 12:565-570.
-
(1995)
Genet. Epidemiol.
, vol.12
, pp. 565-570
-
-
Almasy, L.1
Tierney, C.2
Risch, N.3
-
20
-
-
20444363585
-
A review of the 'Statistical Analysis for Genetic Epidemiology' (S.A.G.E.) software package
-
Elston RC, Gray-McGuire C: A review of the 'Statistical Analysis for Genetic Epidemiology' (S.A.G.E.) software package. Hum Genomics 2004, 1:456-459.
-
(2004)
Hum. Genomics
, vol.1
, pp. 456-459
-
-
Elston, R.C.1
Gray-McGuire, C.2
-
21
-
-
0035742719
-
A tournament of linkage tests in complex inheritance
-
Zhang W, Tapper W, Collins A, et al.: A tournament of linkage tests in complex inheritance. Hum Hered 2001, 52:140-148.
-
(2001)
Hum. Hered.
, vol.52
, pp. 140-148
-
-
Zhang, W.1
Tapper, W.2
Collins, A.3
-
22
-
-
0021957675
-
A comparison of sib-pair linkage tests for disease susceptibility loci
-
Blackwelder WC, Elston RC: A comparison of sib-pair linkage tests for disease susceptibility loci. Genet Epidemiol 1985, 2:85-97.
-
(1985)
Genet. Epidemiol.
, vol.2
, pp. 85-97
-
-
Blackwelder, W.C.1
Elston, R.C.2
-
23
-
-
0031795349
-
Linkage and association
-
Elston RC: Linkage and association. Genet Epidemiol 1998, 15:565-576.
-
(1998)
Genet. Epidemiol.
, vol.15
, pp. 565-576
-
-
Elston, R.C.1
-
24
-
-
0025008677
-
Linkage strategies for genetically complex traits. II. The power of affected relative pairs
-
Risch N: Linkage strategies for genetically complex traits. II. The power of affected relative pairs. Am J Hum Genet 1990, 46:229-241.
-
(1990)
Am. J. Hum. Genet.
, vol.46
, pp. 229-241
-
-
Risch, N.1
-
25
-
-
11144330100
-
Mathematical assumptions versus biological reality: Myths in affected sib pair linkage analysis
-
Elston RC, Song D, Iyengar SK: Mathematical assumptions versus biological reality: myths in affected sib pair linkage analysis. Am J Hum Genet 2005, 76:152-156.
-
(2005)
Am. J. Hum. Genet.
, vol.76
, pp. 152-156
-
-
Elston, R.C.1
Song, D.2
Iyengar, S.K.3
-
26
-
-
0028040135
-
Linkage analysis in nuclear families. 1: Optimality criteria for affected sib-pair tests
-
Knapp M, Seuchter SA, Baur MP: Linkage analysis in nuclear families. 1: Optimality criteria for affected sib-pair tests. Hum Hered 1994, 44:37-43.
-
(1994)
Hum. Hered.
, vol.44
, pp. 37-43
-
-
Knapp, M.1
Seuchter, S.A.2
Baur, M.P.3
-
27
-
-
0028123781
-
Linkage analysis in nuclear families. 2: Relationship between affected sib-pair tests and lod score analysis
-
Knapp M, Seuchter SA, Baur MP: Linkage analysis in nuclear families. 2: Relationship between affected sib-pair tests and lod score analysis. Hum Hered 1994, 44:44-51.
-
(1994)
Hum. Hered.
, vol.44
, pp. 44-51
-
-
Knapp, M.1
Seuchter, S.A.2
Baur, M.P.3
-
28
-
-
0030728925
-
Allele-sharing models: LOD scores and accurate linkage tests
-
Kong A, Cox NJ: Allele-sharing models: LOD scores and accurate linkage tests. Am J Hum Genet 1997, 61:1179-1188.
-
(1997)
Am. J. Hum. Genet.
, vol.61
, pp. 1179-1188
-
-
Kong, A.1
Cox, N.J.2
-
29
-
-
0029046177
-
Complete multipoint sib-pair analysis of qualitative and quantitative traits
-
Kruglyak L, Lander ES: Complete multipoint sib-pair analysis of qualitative and quantitative traits. Am J Hum Genet 1995, 57:439-454.
-
(1995)
Am. J. Hum. Genet.
, vol.57
, pp. 439-454
-
-
Kruglyak, L.1
Lander, E.S.2
-
30
-
-
0029886532
-
Parametric and nonparametric linkage analysis: A unified multipoint approach
-
Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES: Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet 1996, 58:1347-1363.
-
(1996)
Am. J. Hum. Genet.
, vol.58
, pp. 1347-1363
-
-
Kruglyak, L.1
Daly, M.J.2
Reeve-Daly, M.P.3
Lander, E.S.4
-
32
-
-
0031966959
-
Multipoint quantitative-trait linkage analysis in general pedigrees
-
Almasy L, Blangero J: Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 1998, 62:1198-1211.
-
(1998)
Am. J. Hum. Genet.
, vol.62
, pp. 1198-1211
-
-
Almasy, L.1
Blangero, J.2
-
33
-
-
0036338150
-
Merlin - Rapid analysis of dense genetic maps using sparse gene flow trees
-
Abecasis GR, Cherny SS, Cookson WO, Cardon LR: Merlin - rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 2002, 30:97-101.
-
(2002)
Nat. Genet.
, vol.30
, pp. 97-101
-
-
Abecasis, G.R.1
Cherny, S.S.2
Cookson, W.O.3
Cardon, L.R.4
-
34
-
-
0035220056
-
Variance component methods for detecting complex trait loci
-
Blangero J, Williams JT, Almasy L: Variance component methods for detecting complex trait loci. Adv Genet 2001, 42:151-181.
-
(2001)
Adv. Genet.
, vol.42
, pp. 151-181
-
-
Blangero, J.1
Williams, J.T.2
Almasy, L.3
-
35
-
-
0034797728
-
Association analysis in a variance components framework
-
Abecasis GR, Cardon LR, Cookson WO, et al.: Association analysis in a variance components framework. Genet Epidemiol 2001, 21(Suppl 1):S341-S346.
-
(2001)
Genet. Epidemiol.
, vol.21
, Issue.SUPPL. 1
-
-
Abecasis, G.R.1
Cardon, L.R.2
Cookson, W.O.3
-
36
-
-
0035257236
-
Association study designs for complex diseases
-
Cardon LR, Bell JI: Association study designs for complex diseases. Nat Rev Genet 2001, 2:91-99.
-
(2001)
Nat. Rev. Genet.
, vol.2
, pp. 91-99
-
-
Cardon, L.R.1
Bell, J.I.2
-
37
-
-
0036071296
-
Testing for population subdivision and association in four case-control studies
-
Ardlie KG, Lunetta KL, Seielstad M: Testing for population subdivision and association in four case-control studies. Am J Hum Genet 2002, 71:304-311.
-
(2002)
Am. J. Hum. Genet.
, vol.71
, pp. 304-311
-
-
Ardlie, K.G.1
Lunetta, K.L.2
Seielstad, M.3
-
38
-
-
0037442092
-
Population stratification and spurious allelic association
-
Cardon LR, Palmer LJ: Population stratification and spurious allelic association. Lancet 2003, 361:598-604.
-
(2003)
Lancet
, vol.361
, pp. 598-604
-
-
Cardon, L.R.1
Palmer, L.J.2
-
39
-
-
12144285594
-
Assessing the impact of population stratification on genetic association studies
-
Freedman ML, Reich D, Penney KL, et al.: Assessing the impact of population stratification on genetic association studies. Nat Genet 2004, 36:388-393.
-
(2004)
Nat. Genet.
, vol.36
, pp. 388-393
-
-
Freedman, M.L.1
Reich, D.2
Penney, K.L.3
-
40
-
-
2442585696
-
The effects of human population structure on large genetic association studies
-
Marchini J, Cardon LR, Phillips MS, Donnelly P: The effects of human population structure on large genetic association studies. Nat Genet 2004, 36:512-517.
-
(2004)
Nat. Genet.
, vol.36
, pp. 512-517
-
-
Marchini, J.1
Cardon, L.R.2
Phillips, M.S.3
Donnelly, P.4
-
41
-
-
0033926805
-
Association mapping in structured populations
-
Pritchard JK, Stephens M, Rosenberg NA, Donnelly P: Association mapping in structured populations. Am J Hum Genet 2000, 67:170-181.
-
(2000)
Am. J. Hum. Genet.
, vol.67
, pp. 170-181
-
-
Pritchard, J.K.1
Stephens, M.2
Rosenberg, N.A.3
Donnelly, P.4
-
42
-
-
0027377799
-
Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
-
Spielman RS, McGinnis RE, Ewens WJ: Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 1993, 52:506-516.
-
(1993)
Am. J. Hum. Genet.
, vol.52
, pp. 506-516
-
-
Spielman, R.S.1
McGinnis, R.E.2
Ewens, W.J.3
-
43
-
-
0029858544
-
The TDT and other family-based tests for linkage disequilibrium and association
-
Spielman RS, Ewens WJ: The TDT and other family-based tests for linkage disequilibrium and association. Am J Hum Genet 1996, 59:983-989.
-
(1996)
Am. J. Hum. Genet.
, vol.59
, pp. 983-989
-
-
Spielman, R.S.1
Ewens, W.J.2
-
44
-
-
0035055544
-
The family based association test method: Strategies for studying general genotype - Phenotype associations
-
Horvath S, Xu X, Laird NM: The family based association test method: strategies for studying general genotype - phenotype associations. Eur J Hum Genet 2001, 9:301-306.
-
(2001)
Eur. J. Hum. Genet.
, vol.9
, pp. 301-306
-
-
Horvath, S.1
Xu, X.2
Laird, N.M.3
-
45
-
-
0347992868
-
Family-based tests for associating haplotypes with general phenotype data: Application to asthma genetics
-
Horvath S, Xu X, Lake SL, et al.: Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genet Epidemiol 2004, 26:61-69.
-
(2004)
Genet. Epidemiol.
, vol.26
, pp. 61-69
-
-
Horvath, S.1
Xu, X.2
Lake, S.L.3
-
46
-
-
0032897131
-
The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping
-
Teng J, Risch N: The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping. Genome Res 1999, 9:234-241.
-
(1999)
Genome Res.
, vol.9
, pp. 234-241
-
-
Teng, J.1
Risch, N.2
-
47
-
-
0032427048
-
The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling
-
Risch N, Teng J: The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling. Genome Res 1998, 8:1273-1288.
-
(1998)
Genome Res.
, vol.8
, pp. 1273-1288
-
-
Risch, N.1
Teng, J.2
-
48
-
-
6344244729
-
Statistical tests for admixture mapping with case-control and cases-only data
-
Montana G, Pritchard JK: Statistical tests for admixture mapping with case-control and cases-only data. Am J Hum Genet 2004, 75:771-789.
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 771-789
-
-
Montana, G.1
Pritchard, J.K.2
-
49
-
-
0035528928
-
Case-control studies of association in structured or admixed populations
-
Pritchard JK, Donnelly P: Case-control studies of association in structured or admixed populations. Theor Popul Biol 2001, 60:227-237.
-
(2001)
Theor. Popul. Biol.
, vol.60
, pp. 227-237
-
-
Pritchard, J.K.1
Donnelly, P.2
-
50
-
-
0036275126
-
BeadArray technology: Enabling an accurate, cost-effective approach to high-throughput genotyping
-
56-58
-
Oliphant A, Barker DL, Stuelpnagel JR, Chee MS: BeadArray technology: enabling an accurate, cost-effective approach to high-throughput genotyping. Biotechniques 2002, Suppl: 56-58, 60-61.
-
(2002)
Biotechniques
, Issue.SUPPL.
, pp. 60-61
-
-
Oliphant, A.1
Barker, D.L.2
Stuelpnagel, J.R.3
Chee, M.S.4
-
51
-
-
0037685262
-
Multiplexed genotyping with sequence-tagged molecular inversion probes
-
Hardenbol P, Baner J, Jain M, et al.: Multiplexed genotyping with sequence-tagged molecular inversion probes. Nat Biotechnol 2003, 21:673-678.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 673-678
-
-
Hardenbol, P.1
Baner, J.2
Jain, M.3
-
52
-
-
4544335122
-
Guidelines for genotyping in genome-wide linkage studies: Single-nucleotide-polymorphism maps versus microsatellite maps
-
Evans DM, Cardon LR: Guidelines for genotyping in genome-wide linkage studies: single-nucleotide-polymorphism maps versus microsatellite maps. Am J Hum Genet 2004, 75:687-692.
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 687-692
-
-
Evans, D.M.1
Cardon, L.R.2
-
53
-
-
3042548992
-
Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: Comparison with microsatellites
-
John S, Shephard N, Liu G, et al.: Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: comparison with microsatellites. Am J Hum Genet 2004, 75:54-64.
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 54-64
-
-
John, S.1
Shephard, N.2
Liu, G.3
-
54
-
-
8844269435
-
Comparison of microsatellites versus single-nucleotide polymorphisms in a genome linkage screen for prostate cancer-susceptibility Loci
-
Schaid DJ, Guenther JC, Christensen GB, et al.: Comparison of microsatellites versus single-nucleotide polymorphisms in a genome linkage screen for prostate cancer-susceptibility Loci. Am J Hum Genet 2004, 75:948-965.
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 948-965
-
-
Schaid, D.J.1
Guenther, J.C.2
Christensen, G.B.3
-
55
-
-
8844250042
-
Ignoring linkage disequilibrium among tightly linked markers induces false-positive evidence of linkage for affected sib pair analysis
-
Huang Q, Shete S, Amos CI: Ignoring linkage disequilibrium among tightly linked markers induces false-positive evidence of linkage for affected sib pair analysis. Am J Hum Genet 2004, 75:1106-1112.
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 1106-1112
-
-
Huang, Q.1
Shete, S.2
Amos, C.I.3
-
56
-
-
0344441428
-
Estimating recombination rates from population-genetic data
-
Stumpf MP, McVean GA: Estimating recombination rates from population-genetic data. Nat Rev Genet 2003, 4:959-968.
-
(2003)
Nat. Rev. Genet.
, vol.4
, pp. 959-968
-
-
Stumpf, M.P.1
McVean, G.A.2
-
57
-
-
1842435261
-
Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations
-
Crawford DC, Carlson CS, Rieder MJ, et al.: Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations. Am J Hum Genet 2004, 74:610-622.
-
(2004)
Am. J. Hum. Genet.
, vol.74
, pp. 610-622
-
-
Crawford, D.C.1
Carlson, C.S.2
Rieder, M.J.3
-
58
-
-
18444369013
-
The structure of haplotype blocks in the human genome
-
Gabriel SB, Schaffner SF, Nguyen H, et al.: The structure of haplotype blocks in the human genome. Science 2002, 296:2225-2229.
-
(2002)
Science
, vol.296
, pp. 2225-2229
-
-
Gabriel, S.B.1
Schaffner, S.F.2
Nguyen, H.3
-
59
-
-
0034791035
-
High-resolution haplotype structure in the human genome
-
Daly MJ, Rioux JD, Schaffner SF, et al.: High-resolution haplotype structure in the human genome. Nat Genet 2001, 29:229-232.
-
(2001)
Nat. Genet.
, vol.29
, pp. 229-232
-
-
Daly, M.J.1
Rioux, J.D.2
Schaffner, S.F.3
-
60
-
-
0036725017
-
Human genome sequence variation and the influence of gene history, mutation and recombination
-
Reich DE, Schaffner SF, Daly MJ, et al.: Human genome sequence variation and the influence of gene history, mutation and recombination. Nat Genet 2002, 32:135-142.
-
(2002)
Nat. Genet.
, vol.32
, pp. 135-142
-
-
Reich, D.E.1
Schaffner, S.F.2
Daly, M.J.3
-
61
-
-
0043267974
-
Haplotype blocks and linkage disequilibrium in the human genome
-
Wall JD, Pritchard JK: Haplotype blocks and linkage disequilibrium in the human genome. Nat Rev Genet 2003, 4:587-597.
-
(2003)
Nat. Rev. Genet.
, vol.4
, pp. 587-597
-
-
Wall, J.D.1
Pritchard, J.K.2
-
62
-
-
0042387813
-
Assessing the performance of the haplotype block model of linkage disequilibrium
-
Wall JD, Pritchard JK: Assessing the performance of the haplotype block model of linkage disequilibrium. Am J Hum Genet 2003, 73:502-515.
-
(2003)
Am. J. Hum. Genet.
, vol.73
, pp. 502-515
-
-
Wall, J.D.1
Pritchard, J.K.2
-
63
-
-
79959503826
-
The International HapMap Project
-
The International HapMap Project. Nature 2003, 426:789-796.
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
-
64
-
-
13144282294
-
Exhaustive allelic transmission disequilibrium tests as a new approach to genome-wide association studies
-
Lin S, Chakravarti A, Cutler DJ: Exhaustive allelic transmission disequilibrium tests as a new approach to genome-wide association studies. Nat Genet 2004, 36:1181-1188.
-
(2004)
Nat. Genet.
, vol.36
, pp. 1181-1188
-
-
Lin, S.1
Chakravarti, A.2
Cutler, D.J.3
-
65
-
-
18744406980
-
The distribution of long range admixture linkage disequilibrium in an African-American population
-
Rybicki BA, Iyengar SK, Harris T, et al.: The distribution of long range admixture linkage disequilibrium in an African-American population. Hum Hered 2002, 53:187-196.
-
(2002)
Hum. Hered.
, vol.53
, pp. 187-196
-
-
Rybicki, B.A.1
Iyengar, S.K.2
Harris, T.3
-
66
-
-
2342597140
-
A high-density admixture map for disease gene discovery in african americans
-
Smith MW, Patterson N, Lautenberger JA, et al.: A high-density admixture map for disease gene discovery in african americans. Am J Hum Genet 2004, 74:1001-1013.
-
(2004)
Am. J. Hum. Genet.
, vol.74
, pp. 1001-1013
-
-
Smith, M.W.1
Patterson, N.2
Lautenberger, J.A.3
-
67
-
-
13944250687
-
Admixture mapping for hypertension loci with genome-scan markers
-
Zhu X, Luke A, Cooper RS, et al.: Admixture mapping for hypertension loci with genome-scan markers. Nat Genet 2005, 37:177-181.
-
(2005)
Nat. Genet.
, vol.37
, pp. 177-181
-
-
Zhu, X.1
Luke, A.2
Cooper, R.S.3
-
68
-
-
0036799545
-
The allelic architecture of human disease genes: Common disease-common variant...or not?
-
Pritchard JK, Cox NJ: The allelic architecture of human disease genes: common disease-common variant...or not? Hum Mol Genet 2002, 11:2417-2423.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2417-2423
-
-
Pritchard, J.K.1
Cox, N.J.2
-
69
-
-
0037373275
-
Discovering genotypes underlying human phenotypes: Past successes for mendelian disease, future approaches for complex disease
-
Botstein D, Risch N: Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nat Genet 2003, 33(Suppl):228-237.
-
(2003)
Nat. Genet.
, vol.33
, Issue.SUPPL.
, pp. 228-237
-
-
Botstein, D.1
Risch, N.2
-
70
-
-
0035423317
-
Mismatch repair detection (MRD): High-throughput scanning for DNA variations
-
Faham M, Baharloo S, Tomitaka S, et al.: Mismatch repair detection (MRD): high-throughput scanning for DNA variations. Hum Mol Genet 2001, 10:1657-1664.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1657-1664
-
-
Faham, M.1
Baharloo, S.2
Tomitaka, S.3
-
71
-
-
13944265645
-
Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9
-
Cohen J, Pertsemlidis A, Kotowski IK, et al.: Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9. Nat Genet 2005, 37:161-165.
-
(2005)
Nat. Genet.
, vol.37
, pp. 161-165
-
-
Cohen, J.1
Pertsemlidis, A.2
Kotowski, I.K.3
-
72
-
-
3843056691
-
Multiple rare alleles contribute to low plasma levels of HDL cholesterol
-
Cohen JC, Kiss RS, Pertsemlidis A, et al.: Multiple rare alleles contribute to low plasma levels of HDL cholesterol. Science 2004, 305:869-872.
-
(2004)
Science
, vol.305
, pp. 869-872
-
-
Cohen, J.C.1
Kiss, R.S.2
Pertsemlidis, A.3
-
73
-
-
10744233914
-
A tiling resolution DNA microarray with complete coverage of the human genome
-
Ishkanian AS, Malloff CA, Watson SK, et al.: A tiling resolution DNA microarray with complete coverage of the human genome. Nat Genet 2004, 36:299-303.
-
(2004)
Nat. Genet.
, vol.36
, pp. 299-303
-
-
Ishkanian, A.S.1
Malloff, C.A.2
Watson, S.K.3
-
75
-
-
3242808027
-
Large-scale copy number polymorphism in the human genome
-
Sebat J, Lakshmi B, Troge J, et al.: Large-scale copy number polymorphism in the human genome. Science 2004, 305:525-528.
-
(2004)
Science
, vol.305
, pp. 525-528
-
-
Sebat, J.1
Lakshmi, B.2
Troge, J.3
-
76
-
-
10744231187
-
Representational oligonucleotide microarray analysis: A high-resolution method to detect genome copy number variation
-
Lucito R, Healy J, Alexander J, et al.: Representational oligonucleotide microarray analysis: a high-resolution method to detect genome copy number variation. Genome Res 2003, 13:2291-2305.
-
(2003)
Genome Res.
, vol.13
, pp. 2291-2305
-
-
Lucito, R.1
Healy, J.2
Alexander, J.3
-
77
-
-
0033674221
-
Detecting gene copy number fluctuations in tumor cells by microarray analysis of genomic representations
-
Lucito R, West J, Reiner A, et al.: Detecting gene copy number fluctuations in tumor cells by microarray analysis of genomic representations. Genome Res 2000, 10:1726-1736.
-
(2000)
Genome Res.
, vol.10
, pp. 1726-1736
-
-
Lucito, R.1
West, J.2
Reiner, A.3
-
78
-
-
10844232112
-
Whole genome DNA copy number changes identified by high density oligonucleotide arrays
-
Huang J, Wei W, Zhang J, et al.: Whole genome DNA copy number changes identified by high density oligonucleotide arrays. Hum Genomics 2004, 1:287-299.
-
(2004)
Hum. Genomics
, vol.1
, pp. 287-299
-
-
Huang, J.1
Wei, W.2
Zhang, J.3
-
79
-
-
2442671820
-
Allelic imbalance analysis by high-density single-nucleotide polymorphic allele (SNP) array with whole genome amplified DNA
-
Wong KK, Tsang YT, Shen J, et al.: Allelic imbalance analysis by high-density single-nucleotide polymorphic allele (SNP) array with whole genome amplified DNA. Nucleic Acids Res 2004, 32:e69.
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Wong, K.K.1
Tsang, Y.T.2
Shen, J.3
-
80
-
-
4544354302
-
Concurrent analysis of loss of heterozygosity (LOH) and copy number abnormality (CNA) for oral premalignancy progression using the Affymetrix 10K SNP mapping array
-
Zhou X, Mok SC, Chen Z, et al.: Concurrent analysis of loss of heterozygosity (LOH) and copy number abnormality (CNA) for oral premalignancy progression using the Affymetrix 10K SNP mapping array. Hum Genet 2004, 115:327-330.
-
(2004)
Hum. Genet.
, vol.115
, pp. 327-330
-
-
Zhou, X.1
Mok, S.C.2
Chen, Z.3
-
81
-
-
0142209375
-
Genomic priorities and public health
-
Merikangas KR, Risch N: Genomic priorities and public health. Science 2003, 302:599-601.
-
(2003)
Science
, vol.302
, pp. 599-601
-
-
Merikangas, K.R.1
Risch, N.2
|