A comparative sequence analysis reveals a common GBD/FH3-FH1-FH2-DAD architecture in formins from Dictyostelium, fungi and metazoa

BMC Genomics

Volumn 6, Issue , 2005, Pages

  Rivero, Francisco ^a   Muramoto, Tetsuya ^c   Meyer, Ann Kathrin ^a   Urushihara, Hideko ^c   Uyeda, Taro Q P ^b   Kitayama, Chikako ^b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; COMPLEMENTARY DNA; ISOPROTEIN; METHENAMINE; PROFILIN; PROLINE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RNA;

ARTICLE; CELL FUSION; COMPARATIVE GENE MAPPING; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DICTYOSTELIUM DISCOIDEUM; DNA SEQUENCE; EUKARYOTE; FUNGUS; GENE EXPRESSION PROFILING; GENETIC VARIABILITY; METAZOON; MOLECULAR PHYLOGENY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DOMAIN; PROTEIN STRUCTURE; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SEXUAL DEVELOPMENT;

AMOEBA (GENUS); DICTYOSTELIUM; DICTYOSTELIUM DISCOIDEUM; EUKARYOTA; FUNGI; METAZOA;

EID: 20444381052     PISSN: 14712164     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-6-28     Document Type: Article

References (50)

1. Zigmond SH: Formin-induced nucleation of actin filaments. Curr Opin Cell Biol 2004, 16:99-105.
2. Zeller R, Jackson-Grusby L, Leder P: The limb deformity gene is required for apical ectodermal ridge differentiation and anteroposterior limb pattern formation. Genes Dev 1989, 3:1481-1592.
3. Castrillon DH, Wasserman SA: Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene. Development 1994, 120:3367-3377.
4. Evangelista M, Blundell K, Longtine MS, Chow CJ, Adames N, Pringle JR, Peter M, Boone C: Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis. Science 1997, 276:118-122.
5. Chang F, Drubin D, Nurse P: cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin. J Cell Biol 1997, 137:169-182.
6. Wallar BJ, Alberts AS: The formins: active scaffolds that remodel the cytoskeleton. Trends Cell Biol 2003, 13:435-466.
7. Evangelista M, Zigmond S, Boone C: Formins: signaling effectors for assembly and polarization of actin filaments. J Cell Sci 2003, 116:2603-2611.
8. Higgs HN, Pollard TD: Regulation of actin filament network formation through Arp2/3 complex: activation by a diverse array of proteins. Annu Rev Biochem 2001, 70:649-676.
9. Pruyne D, Evangelista M, Yang C, Bi E, Zigmond S, Bretscher A, Boone C: Role of formins in actin assembly: nucleation and barbedend association. Science 2002, 297:612-615.
10. Li F, Higgs HN: The mouse formin, mDia, is a potent actin nucleation factor regulated by auto-inhibition. Curr Biol 2003, 13:1335-1340.
11. Kovar DR, Kuhn JR, Tichy AL, Pollard TD: The fission yeast cytokinesis formin Cdc12p is a barbed end actin filament capping protein gated by profilin. J Cell Biol 2003, 161:875-887.
12. Shimada A, Nyitrai M, Vetter IR, Kühlmann D, Bugyi B, Narumiya S, Geeves MA, Wittinghoffer A: The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization. Mol Cell 2004, 13:511-522.
13. Xu Y, Moseley JB, Sagot I, Poy F, Pellman D, Goode BL, Eck MJ: Crystal structures of a formin homology-2 domain reveal a tethered dimer architecture. Cell 2004, 116:711-723.
14. Petersen J, Nielsen O, Egel R, Hagan IM: FH3, a domain found in formins, targets the fission yeast formin Fus1 to the projection tip during conjugation. J Cell Biol 1998, 141:1217-1228.
15. Deeks MJ, Hussey PJ, Davies B: Formins: intermediates in signal transduction cascades that affect cytoskeletal organization. Trends Plant Sci 2002, 7:492-498.
16. Cvrčkov ́F, Novotný M, Pícková D, Žárský V: Formin homology 2 domains occur in multiple contexts in angiosperms. BMC Genomics 2004, 5:44.
17. Alberts AS: Identification of a carboxyl-terminal Diaphanous-related formin homology protein autoregulatory domain. J Biol Chem 2001, 276:2824-2830.
18. Noegel AA, Schleicher M: The actin cytoskeleton of Dictyostelium: a story told by mutants. J Cell Sci 2000, 113:759-766.
19. Rivero F, Somesh BP: Signal transduction pathways regulated by Rho GTPases in Dictyostelium. J Muscle Res Cell Motil 2002, 23:737-749.
20. Kitayama C, Uyeda TQP: ForC, a novel type of formin family protein lacking an FH1 domain, is involved in multicellular development in Dictyostelium discoideum. J Cell Sci 2003, 116:711-723.
21. Watanabe N, Kato T, Fujita A, Ishizaki T, Narumiya S: Cooperation between mDia1 and ROCK in Rho-induced actin reorganization. Nat Cell Biol 1999, 1:136-143.
22. Ishizaki T, Morishima Y, Okamoto M, Furuyashiki T, Kato T, Narumiya S: Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1. Nat Cell Biol 2001, 3:8-14.
23. Evangelista M, Pruyne D, Amberg DC, Boone C, Bretscher A: Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast. Nat Cell Biol 2002, 4:260-269.
24. Sagot I, Klee SK, Pellman D: Yeast formins regulate cell polarity by controlling the assembly of actin cables. Nat Cell Biol 2002, 4:42-50.
25. Holt MR, Koffer A: Cell motility: proline-rich proteins promote protrusions. Trends Cell Biol 2001, 11:38-46.
26. Macías MJ, Wiesner S, Sudol M: WW and SH3 domains, two different scaffolds to recognize proline-rich ligands. FEBS Lett 2002, 513:30-37.
27. Kobielak A, Pasolli HA, Fuchs E: Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables. Nature Cell Biol 2004, 6:21-30.
28. Fujiwara T, Tanaka K, Mino A, Kikyo M, Takahashi K, Shimizu K, Takai Y: Rho1p-Bni1p-Spa2p interactions: implication in localization at the bud site and regulation of the actin cytoskeleton in Saccharomyces cerevisiae. Mol Biol Cell 1998, 9:1221-1233.
29. Rizo J, Sudhof TC: C2-domains, structure and function of a universal Ca2+-binding domain. J Biol Chem 1998, 273:15879-15882.
30. Hurley JH, Newton AC, Parker PJ, Blumberg PM, Nishizuka Y: Taxonomy and function of C1 protein kinase C homology domains. Protein Sci 1997, 6:477-480.
31. Durocher D, Henckel J, Fersht AR, Jackson SP: The FHA domain is a modular phosphopeptide recognition motif. Mol Cell 1999, 4:387-394.
32. Saga Y, Okada H, Yanagisawa K: Macrocysts development in Dictyostelium. II. Mating-type-specific cell fusion and acquisition of fusion-competence. J Cell Sci 1983, 60:157-168.
33. Muramoto T, Suzuki K, Shimizu H, Kohara Y, Kohriki E, Obara S, Tanaka Y, Urushihara H: Construction of a gamete-enriched gene pool and RNAi-mediated functional analysis in Dictyostelium discoideum. Mech Dev 2003, 120:965-975.
34. Miyagi Y, Yamashita T, Fukaya M, Sonoda T, Okuno T, Yamada K, Watanabe M, Nagashima Y, Aoki I, Okuda K, Mishina M, Kawamoto S: Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor delta 2 subunit. J Neurosci 2002, 22:803-814.
35. Katoh M, Katoh M: Identification and characterization of human DIAPH3 gene in silico. Int J Mol Med 2004, 13:473-478.
36. Yasuda S, Oceguera-Yanez F, Kato T, Okamoto M, Yonemura S, Terada Y, Ishizaki T, Narumiya S: Cdc42 and mDia3 regulate microtubule attachment to chinetochores. Nature 2004, 428:767-771.
37. Peng J, Wallar BJ, Flanders A, Swiatek PJ, Alberts AS: Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42. Curr Biol 2003, 13:534-545.
38. Yayoshi-Yamamoto S, Taniuchi I, Watanabe T: FRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophages. Mol Cell Biol 2000, 20:6872-6881.
39. Westendorf JJ: The formin/diaphanous-related protein, FHOS, interacts with Rac1 and activates transcription from the serum response element. J Biol Chem 2001, 276:46453-46459.
40. Nakano K, Imai J, Arai R, Toh-e A, Matsui Y, Mabuchi I: The small GTPase Rho3 and the diaphanous/formin For3 function in polarized cell growth in fission yeast. J Cell Sci 2002, 115:4629-4639.
41. Magie CR, Meyer MR, Gorsuch MS, Parkhurst SM: Mutations in the Rho1 small GTPase disrupt morphogenesis and segmentation during early Drosophila development. Development 1999, 126:5353-5364.
42. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ: Basic local alignment search tool. J Mol Biol 1990, 215:403-410.
43. Dictybase, an online informatics resource for Dictyostelium. [http://dictybase.org]
44. National Center for Biotechnology Information. BLAST [http://www.ncbi.nlm.nih.gov/BLAST/]
45. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG: The ClustalX windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 1997, 25:4876-4882.
46. Hall TA: BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucl Acids Symp Ser 1999, 41:95-98.
47. Page RDM: TREEVIEW: An application to display phylogenetic trees on personal computers. Comput Applic Biosci 1996, 12:357-358.
48. Simple Modular Architecture Research Tool [http://smart.embl-heidelberg.de/]
49. InterProScan [http://www.ebi.ac.uk/InterProScan/]
50. Sussman M: Cultivation and synchronous morphogenesis of Dictyostelium under controlled experimental conditions. In Methods in Cell Biology Volume 28. Edited by: Spudich JA. San Diego: Academic Press; 1987:9-29.