Administration of monoclonal antibodies neutralizing the inflammatory mediators tumor necrosis factor alpha and interleukin -6 does not attenuate acute behavioral deficits following experimental traumatic brain injury in the rat

Restorative Neurology and Neuroscience

Volumn 23, Issue 1, 2005, Pages 31-42

  Marklund, Niklas ^a   Keck, Carrie ^a   Hoover, Rachel ^a   Soltesz, Kristie ^a   Millard, Marie ^a   Lebold, David ^a   Spangler, Zachary ^a   Banning, Adrian ^a   Benson, Jacqueline ^b   McIntosh, Tracy K ^a,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CENTOCOR INC   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Cerebral edema; Inflammation; Interleukin (IL) 6; Lateral fluid percussion; Morris water maze; Neuroscore; Rotating pole; Traumatic brain injury; Tumor necrosis factor (TNF)

Indexed keywords

IMMUNOGLOBULIN G; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; MONOCLONAL ANTIBODY; PHENOBARBITAL; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR DISORDER; BRAIN EDEMA; BRAIN INJURY; COGNITION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE SEVERITY; HEMISPHERE; LEARNING; MALE; MAZE TEST; MOTOR PERFORMANCE; NONHUMAN; OUTCOMES RESEARCH; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIBODIES, MONOCLONAL; BRAIN EDEMA; BRAIN INJURIES; COGNITION DISORDERS; INFLAMMATION MEDIATORS; INTERLEUKIN-6; LEARNING; MALE; MOTOR SKILLS; RATS; RATS, SPRAGUE-DAWLEY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 20244371332     PISSN: 09226028     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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