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Volumn 36, Issue 1, 2001, Pages 55-61
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New 3-[4-(aryl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)propane derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants
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Author keywords
5 HT1A antagonist; Antidepressant; Arylpiperazines; Serotonin reuptake inhibitor
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Indexed keywords
1 (2 METHOXYPHENYL) 4 (4 PHTHALIMIDOBUTYL)PIPERAZINE;
1 (5 CHLOROBENZO[B]THIOPHEN 3 YL) 3 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]PROPAN 1 OL;
1 (5 FLUOROBENZO[B]THIOPHEN 3 YL) 3 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]PROPAN 1 OL;
ANTIDEPRESSANT AGENT;
BENZOTHIOPHENE DERIVATIVE;
DULOXETINE;
FLUOXETINE;
N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE;
PROPANE;
SEROTONIN 1A ANTAGONIST;
SEROTONIN 1A RECEPTOR;
SEROTONIN TRANSPORTER;
SEROTONIN UPTAKE INHIBITOR;
UNCLASSIFIED DRUG;
ANIMAL TISSUE;
ARTICLE;
BINDING AFFINITY;
CONTROLLED STUDY;
DRUG ACTIVITY;
DRUG MECHANISM;
DRUG RECEPTOR BINDING;
DRUG SCREENING;
DRUG SYNTHESIS;
NONHUMAN;
RAT;
ANIMALS;
ANTIDEPRESSIVE AGENTS;
BINDING, COMPETITIVE;
CARRIER PROTEINS;
DOSE-RESPONSE RELATIONSHIP, DRUG;
GTP-BINDING PROTEINS;
GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE);
HIPPOCAMPUS;
MEMBRANE GLYCOPROTEINS;
MEMBRANE TRANSPORT PROTEINS;
NERVE TISSUE PROTEINS;
PIPERAZINES;
RATS;
RECEPTORS, SEROTONIN;
RECEPTORS, SEROTONIN, 5-HT1;
SEROTONIN ANTAGONISTS;
SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS;
SEROTONIN UPTAKE INHIBITORS;
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EID: 0035111317
PISSN: 02235234
EISSN: None
Source Type: Journal
DOI: 10.1016/S0223-5234(00)01198-3 Document Type: Article |
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Times cited : (48)
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References (24)
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