ANOVA, a putative astrocytic RNA-binding protein gene that maps to chromosome 19q13.3

Neurogenetics

Volumn 1, Issue 1, 1997, Pages 31-36

  Ueki, Keisuke ^a   Ramaswamy, Shivapriya ^a   Billings, Stephanie J ^a   Mohrenweiser, Harvey W ^b   Louis, David N ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

Author keywords

Chromosome 19; Glioma; NOVA; RNA binding

Indexed keywords

COMPLEMENTARY DNA; NERVE PROTEIN; NOVA2 PROTEIN, HUMAN; RNA BINDING PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; ASTROCYTE; BRAIN; CHROMOSOME 19; COSMID; GENE LIBRARY; GENETICS; GLIOMA; HUMAN; IN SITU HYBRIDIZATION; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; SEQUENCE HOMOLOGY; SINGLE STRAND CONFORMATION POLYMORPHISM; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ASTROCYTES; BASE SEQUENCE; BLOTTING, NORTHERN; BRAIN; CHROMOSOMES, HUMAN, PAIR 19; CLONING, MOLECULAR; COSMIDS; DNA, COMPLEMENTARY; GENE LIBRARY; GLIOMA; HUMANS; IN SITU HYBRIDIZATION; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RNA-BINDING PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TISSUE DISTRIBUTION;

EID: 0031128823     PISSN: 13646745     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100480050005     Document Type: Article

References (28)

1. Rubio, M.-P., Correa, K. M., Ueki, K., Mohrenweiser, H. W., Gusella, J. F., von Deimling, A., and Louis, D. N. (1994) The putative glioma tumor suppressor gene on chromosome 19q maps between APOC2 and HRC. Cancer Res., 54, 4760-4763.
2. Yong, W. H., Chou, D., Ueki, K., Harsh, G. R., von Deimling, A., Gusella, J. F., Mohrenweiser, H. W., and Louis, D. N. (1995) Chromosome 19q deletions in human gliomas overlap telomeric to D19S219 and may target a 425 kb region centromeric to D19S112. J. Neuropathol. Exp. Neurol., 54, 622-626.
3. Yong, W. H., Ueki, K., Chou, D., Reeves, S. A., von Deimling, A., Gusella, J. F., Mohrenweiser, H. W., Buckler, A. J., and Louis, D. N. (1995) Cloning of a highly conserved human protein serine threonine phosphatase gene from the glioma candidate region on chromosome 19q13.3. Genomics, 29, 533-536.
4. Gordon, L. A., Bergmann, A., Christensen, M., Danganan, L., Lee, D. A., Ashworth, L. K., Nelson, D. O., Olsen, A. S., Mohrenweiser, H. W., Carrano, A. V., and Brandriff, B. F. (1995) A 30-Mb metric fluorescence in situ hybridization map of human chromosome 19q. Genomics, 30, 187-192.
5. Ashworth, L. K., Batzer, M. A., Brandriff, B., Branscomb, E., de Jong, P., Garcia, E., Garnes, J. A., Gordon, L. A., Lamerdin, J. E., Lennon, G., Mohrenweiser, H., Olsen, A. S., Slezak, T., and Carrano, A. V. (1995) An integrated metric physical map of human chromosome 19. Nature Genet., 11, 422-427.
6. Buckler, A. J., Chang, D. D., Graw, S. L., Brook, J. D., Haber, D. A., Sharp, P. A., and Housman, D. E. (1991) Exon amplification: a strategy to isolate mammalian genes based on RNA splicing. Proc. Natl. Acad. Sci. USA, 88, 4005-4009.
7. Church, D. M., Stotler, C. J., Rutter, J. L., Murrell, J. R., Trofatter, J. A., and Buckler, A. J. (1994) Isolation of genes from complex sources of mammalian genomic DNA using exon amplification. Nature Genet., 6, 98-105.
8. Trofatter, J. A., Long, K. R., Murrell, J. R., Stotler, C. J., Gusella, J. F., and Buckler, A. J. (1995) An expression-independent catalogue of genes from human chromosome 22. Genome Res., 5, 214-224.
9. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Press, Cold Spring Harbor.
10. Rubio, M.-P., von Deimling, A., Yandell, D. W., Wiestier, O. D., Gusella, J. F., and Louis, D. N. (1993) Accumulation of wild-type p53 protein in human astrocytomas. Cancer Res., 53, 3465-3467.
11. Buckanovich, R. J., Posner, J. B., and Darnell, R. B. (1993) Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system. Neuron, 11, 657-672.
12. Buckanovich, R. j., Yang, Y Y L., and Darnell, R. B. (1996) Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies. J. Neuroscience, 16, 1114-1122.
13. Kozak, M. (1986) Point mutations define a sequence franking the AUG initiator codon that modulates transcription by eukaryotic ribosomes. Cell, 44, 283-292.
14. Musco, G., Stier, G., Joseph, C., Morelli, M. A. C., Nilges, M., Gibson, T. J., and Pastore, A. (1996) Three-dimensional structure and stability of the KH domain: molecular insigts into the fragile X syndrome. Cell, 85, 237-245.
15. Hormigo, A., Dalmau, J., Rosenblum, M. K., River, M. E., and Posner, J. B. (1994) Immunological and pathological study of anti-Ri-associated encephalopathy. Ann. Neurol., 36, 896-902.
16. Luque, F. A., Furneaux, H. M., Ferziger, R., Rosenblum, M. K., Wray, S. H., Schold, J. S. C., Glantz, M. J., Jaecle, K. A., Biran, H., Lesser, M., Paulsen, W. A., River, M. E., and Posner, J. B. (1991) Anti-Ri: an antibody associated with paraneoplastic opsoclonus and breast cancer. Ann. Neurol., 29, 241-251.
17. Matunis, M. J., Michel, W. M., and Dreyfuss, G. (1992) Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein. Mol. Cell. Biol., 12, 164-171.
18. Burd, C. G., and Dreyfuss, G. (1994) Conserved structure and diversity of functions of RNA-binding proteins. Science, 265, 615-621.
19. Verkerk, A. J. M. H., Pieretti, M., Sutcliffe, J. S., Fu, Y-H., Kuhl, D. P. A., Pizutti, A., Reiner, O., Richards, S., Victoria, M. F., Zhang, F., Eussen, B. E., van Ommen, G. J. B., Blonden, L. A. J., Riggins, G. J., Chastain, J. L., Kunst, C. B., Galjaard, H., Caskey, C. T., Nelson, D. L., Oostra, B. A., and Warren, S. T. (1991) Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell, 65, 905-914.
20. De Boulle, K., Verkerk, A. J. M. H., Reyniers, E., Vits, L., Hendrickx, J., Van Roy, B., Van Den Vos, F., de Graaff, E., Oostra, B. A., and Williams, P. J. (1993) A point mutation in the FMR-1 gene assocated with fragile X mental retardation. Nature Genet., 3, 31-35.
21. Smoller, D., Friedel, C., Schmid, A., Bettler, D., Lam, L., and Yedvobnick, B. (1990) The Drosophila neurogenic locus mastermind encodes a nuclear protein unusually rich in amino acid homopolymers. Genes Dev., 4, 1688-1700.
22. Leffers, H., Dejgaard, k., and Celis, J. E. (1995) Characterization of two major cellular poly(C)-binding proteins, each containing three K-homologous (KH) domains. Eur. J. Biochem., 230, 447-453.
23. Michelotti, E. F., Michelotti, G. A., Aronsohn, A. I., and Levens, D. (1996) Heterogeneous nuclear ribonucleoprotein K is a transcriptional factor. Mol. Cell. Biol., 16, 2350-2360.
24. Bustelo, X. R., Suen, K., Michael, W. M., Greyfuss, G., and Barbacid, M. (1995) Association of the vav proto-oncogene product with poly(rC)-specific RNA-binding proteins. Mol. Cell. Biol., 15, 1324-1332.
25. Szabo, A., Dalmau, J., Manley, G., Rosenfeld, M., Wong, E., Henson, J., Posner, J. B., and Furneaux, H. M. (1991) HuD, a pareneoplastic encephalomyelitis antigen, contains PNA-binding domains and is homologous to elav and sex-lethal. Cell, 67, 325-333.
26. Dejgaard, K., Leffers, H., Rasmussen, H. H., Madsen, P., Kruse, T. A., Gesser, B., Nielsen, H., and Celis, J. E. (1994) Identification, molecular cloning, expression and chromosomal mapping of a family of transformation upregulated hnRNP-K proteins derived by alternative splicing. J. Mol. Biol., 236, 33-48.
27. Honnorat, J., Antoine, J. C., Derrington, E., Aguera, M., and F., B. M. (1996) Antibodies to a subpopulation of glial cells and a 66 kDa developmental protein in patients with paraneoplastic neurological syndromes. J. Neurol. Neurosurg. Psych., 61, 270-278.
28. Rosenberg, J. E., Lisle, D. K., Burwick, J. A., Ueki, K., von Deimling, A., Mohrenweiser, H. W., and Louis, D. N. (1996) Refined deletion mapping of the chromosome 19q glioma tumor suppressor gene to the D19S412-STD interval. Oncogene, 13, 2483-2485.