Evolving significance of prognostic markers associated with new treatment strategies in neuroblastoma

Cancer Letters

Volumn 197, Issue 1-2, 2003, Pages 119-124

  Mora, Jaume ^a   Gerald, William L ^b   Cheung, Nai Kong V ^b  

^a HOSPITAL SANT JOAN DE DÉU   (Spain)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

19q13; Gene expression; Genetic classification; Genetic heterogeneity; Local regional neuroblastoma; Loss of heterozygosity; Metastasis; Microarray analysis; MYCN; Neuroblastoma; Ploidy; Prognostic markers; Relapse; Risk

Indexed keywords

FERRITIN; LACTATE DEHYDROGENASE; TUMOR MARKER;

AGE DISTRIBUTION; CANCER GROWTH; CANCER RISK; CANCER STAGING; CANCER SURVIVAL; CHROMOSOME 11Q; CHROMOSOME 14Q; CHROMOSOME 19Q; CHROMOSOME 1P; CHROMOSOME 9P; CONFERENCE PAPER; CORRELATION ANALYSIS; DNA MICROARRAY; GENE EXPRESSION PROFILING; HETEROZYGOSITY LOSS; HISTOPATHOLOGY; HUMAN; METASTASIS; MULTIVARIATE ANALYSIS; NEUROBLASTOMA; ONCOGENE C MYB; PLOIDY; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; TRIPLOIDY; VALIDATION PROCESS;

EID: 0038444702     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(03)00094-6     Document Type: Conference Paper

References (15)

1. Mora J., Cheung N.K.V., Gerald W. Genetic heterogeneity and clonal evolution in neuroblastoma. Br. J. Cancer. 85:2001;182-189.
2. Maris J.M., Matthay K.K. Molecular biology of neuroblastoma. J. Clin. Oncol. 17:1999;2264-2279.
3. Kushner B.H., Cheung N.K.V., LaQuaglia M.P., Ambros P.F., Ambros I.M., Bonilla M.A., Gerald W.L., Ladanyi M., Gilbert F., Rosenfield N.S., Yeh S.D.J. Survival from locally invasive or widespread neuroblastoma without cytotoxic therapy. J. Clin. Oncol. 14:1996;373-381.
4. Mora J., Gerald W., Chen L., Qin J., Cheung N.K. Survival analysis of clinical, pathologic and genetic features in neuroblastoma presenting as local-regional disease. Cancer. 91:2001;435-442.
5. Mora J., Cheung N.K.V., Juan G., Illei P., Cheung I., Chi S., Ladanyi M., Cordon-Cardo C., Gerald W.L. Schwannian cells of neuroblastoma are derived from a tumoral cell progenitor. Cancer Res. 61:2001;6892-6898.
6. Palitti F., Rizzoni M. Pattern of DNA segregation in multipolar anatelophases of different ploidy in euploid and aneuploid mammalian cells cultivated in vitro. Genetica. 43:1972;130-147.
7. Mora J., Oplanic S., Chen L., Cheung N.K.V., Gerald W. Novel regions of allelic imbalance identified by genome-wide analysis of neuroblastoma. Cancer Res. 62:2002;1761-1767.
8. Mora J., Cheung N.K.V., Chen L., Qin J., Gerald W. Loss of heterozygosity at 19q13.3 is associated with locally aggressive neuroblastoma. Clin. Cancer Res. 7:2001;1358-1361.
9. Cheung N.K.V., Kushner B.H., LaQuaglia M.P., Kramer K., Gollamudi S., Heller G., Gerald W., Yeh S., Finn R., Larson S.M., Wuest D., Byrnes M., Dantis E., Mora J., Cheung I.Y., Rosenfield N., Abramson S., O'Reilly R.J. N7: a novel multi-modality therapy of high risk neuroblastoma in children diagnosed over 1 year of age. Med. Ped. Oncol. 36:2001;227-230.
10. Kushner B.H., LaQuaglia M.P., Bonilla M.A., Lindsley K., Rosenfield N., Yeh S., Eddy J., Gerald W.L., Heller G., Cheung N.K.V. Highly effective induction therapy for stage 4 neuroblastoma in children over 1 year of age. J. Clin. Oncol. 12:1994;2607-2613.
11. Mora J., Gerald W., Qin J., Cheung N.K.V. Evolving significance of prognostic markers associated with treatment success in stage 4 neuroblastoma. Cancer. 94:2002;2756-2765.
12. Maris J.M., Weiss M.J., Guo C., Gerbing R.B., Stram D.O., White P.S., Hogarty M.D., Sulman E.P., Thompson P.M., Lukens J.N., Matthay K.K., Seeger R.C., Brodeur G.M. Loss of heterozygosity at 1p36 independently predicts for disease progression but not decreased overall survival probability in neuroblastoma patients: a Children's Cancer Group study. J. Clin. Oncol. 18:2000;1888-1899.
13. Bown N., Cotterill S., Lastowska M., O'Neill S., Pearson A.D.J., Plantaz D., Meddeb M., Danglot G., Brinkschmidt C., Christiansen H., Laureys G., Speleman F. Gain of chromosome 17 and adverse outcome in patients with neuroblastoma. N. Engl. J. Med. 340:1999;1954-1961.
14. Bowman L.C., Hancock M.L., Santana V.M., Hayes F.A., Kun L., Parham D.M., Furman W.L., Rao B.N., Green A.A., Crist W.M. Impact of intensified therapy on clinical outcome in infants and children with neuroblastoma: the St Jude Children's Research Hospital experience, 1962-1988. J. Clin. Oncol. 9:1991;1599-1608.
15. Caron H., van Sluis P., de Kraker J., Bokkerink J., Egeler M., Laureys G., Slater R., Westerveld A., Voute P.A., Versteeg R. Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma. N. Engl. J. Med. 334:1996;225-230.