A SNP Map of the Rat Genome Generated from cDNA Sequences

Science

Volumn 303, Issue 5659, 2004, Pages 807-

  Zimdahl, Heike ^a   Nyakatura, Gerald ^b   Brandt, Petra ^b   Schulz, Herbert ^a   Hummel, Oliver ^a,c   Fartmann, Berthold ^b   Brett, David ^b   Droege, Marcus ^b   Monti, Jan ^a   Lee, Young Ae ^a   Sun, Yinyan ^a,c   Zhao, Shaying ^d   Winter, Eitan E ^e   Ponting, Chris P ^e   Chen, Yuan ^f   Kasprzyk, Arek ^f   Birney, Ewan ^f   Ganten, Detlev ^a   Hubner, Norbert ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b MWG Biotech AG   (Germany)

^c MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^d J CRAIG VENTER INSTITUTE   (United States)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASE CONTROL; DNA; HUMAN ENGINEERING;

NUCLEOTIDES; RAT GENOME;

GENES;

COMPLEMENTARY DNA;

GENOME;

ARTICLE; DNA LIBRARY; GENE LOCUS; GENE MAPPING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; CHROMOSOME MAPPING; COMPUTATIONAL BIOLOGY; DATABASES, NUCLEIC ACID; DNA, COMPLEMENTARY; GENE LIBRARY; GENOME; HAPLOTYPES; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RATS, SPRAGUE-DAWLEY; SEQUENCE ALIGNMENT; TRANSCRIPTION, GENETIC;

RODENTIA;

EID: 10744225849     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1092427     Document Type: Article

References (9)

1. Rat Genome Sequencing Project Consortium. Data available from www.hgsc.bcm.tmc.edu/projects/rat/.
2. Materials and Methods are available as supporting online material on Science Online.
3. Z. Ning, A. J. Cox, J. C. Mullikin. Genome Res. 11, 1725 (2001).
4. K. Lindblad-Toh et al., Nature Genet. 24, 38 (2000).
5. International 5NP Map Working Group, Nature 409, 928 (2001).
6. C. M. Wade et al., Nature 420, 574 (2002).
7. J. T. Mendell, H. C. Dietz. Cell 107, 411 (2001).
8. All SNP data aligned to the assembled rat genome sequence and annotation with respect to described genes and genomic features are incorporated into the ENSEMBL database (www.ensembl.org). Integrating our data into the ENSEMBL database allows it to be visualized within the context of the growing body of information about the human and other genome sequences represented. Additionally, all data can be found at dbSNP (www.ncbi.nlm.nih.gov/5NP), which details the exact allelic variant of the described SNP. SNPs can be accessed from dbSNP and ENSEMBL databases using accession numbers ss16343960 to ss16355610.
9. We thank all members of the Rat Genome Sequencing Project Consortium for providing the assembled rat genome sequence. We also thank H. Lehrach and T. J. Altman for comments on the manuscript. Supported by MWG and by a grant from the NGFN/ BMBF (German Ministry for Research and Education) to N.H.