Structural Basis for Differences in Substrate Selectivity in Kex2 and Furin Protein Convertases

Biochemistry

Volumn 43, Issue 9, 2004, Pages 2412-2421

  Holyoak, Todd ^a   Kettner, Charles A ^b   Petsko, Gregory A ^a   Fuller, Robert S ^c   Ringe, Dagmar ^a  

^a BRANDEIS UNIVERSITY   (United States)

^b DUPONT COMPANY   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; ION SOURCES; ORGANIC ACIDS; PROTEINS;

MONOVALENCY;

BIOCHEMISTRY;

BORONIC ACID DERIVATIVE; CATION; FUNGAL PROTEIN; FURIN; POTASSIUM ION; PROTEIN KEX2; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; MOLECULAR RECOGNITION; PRIORITY JOURNAL;

BINDING SITES; BORONIC ACIDS; CRYSTALLOGRAPHY, X-RAY; FURIN; OLIGOPEPTIDES; PROPROTEIN CONVERTASES; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

MAMMALIA;

EID: 1542297713     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035849h     Document Type: Article

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