Identification of the main human cytochrome P450 enzymes involved in safrole 1′-hydroxylation

Chemical Research in Toxicology

Volumn 17, Issue 8, 2004, Pages 1151-1156

  Ueng, Yune Fang ^a,c   Hsieh, Chih Hang ^b   Don, Ming Jaw ^a   Chi, Chin Wen ^b,d   Ho, Li Kang ^b  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

1' HYDROXYSAFROLE; 4 METHYLPYRAZOLE; CHLORZOXAZONE; CYTOCHROME P450; CYTOCHROME P450 2C9; CYTOCHROME P450 2E1; CYTOCHROME P450 INHIBITOR; DIETHYLDITHIOCARBAMIC ACID; ESSENTIAL OIL; SAFROLE; SULFAPHENAZOLE; SULFATE; TOLBUTAMIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BACTERIAL MEMBRANE; CARCINOGENICITY; CATALYSIS; CONTROLLED STUDY; DNA ADDUCT; ENZYME ACTIVITY; ENZYME ANALYSIS; ESCHERICHIA COLI; FEMALE; HUMAN; HUMAN TISSUE; HYDROXYLATION; LIVER MICROSOME; MALE; MICHAELIS CONSTANT; MOUSE; NONHUMAN; PLANT; RAT; SASSAFRAS; SULFONATION;

CYTOCHROME P-450 ENZYME SYSTEM; DNA ADDUCTS; ENZYME INHIBITORS; ESCHERICHIA COLI; HUMANS; HYDROXYLATION; MICROSOMES, LIVER; SAFROLE;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; SASSAFRAS;

EID: 4243125326     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx030055p     Document Type: Article

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