Advances in the molecular diagnosis of ochratoxin A-producing fungi

Food Additives and Contaminants

Volumn 22, Issue 4, 2005, Pages 324-334

  Niessen, L ^a   Schmidt, H ^a   Muhlencoert E ^a   Farber P ^b   Karolewiez, A ^b   Geisen, R ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b FEDERAL RESEARCH INSTITUTE OF NUTRITION AND FOOD   (Germany)

Author keywords

Aspergillus; Biosynthesis; Coffee; Diagnosis; Grape products; Ochratoxin A; PCR; Penicillium; Wheat

Indexed keywords

CALMODULIN; OCHRATOXIN;

ARTICLE; ASPERGILLUS; ASPERGILLUS OCHRACEUS; BIOSYNTHESIS; FOOD CONTAMINATION; FOOD INDUSTRY; FOOD PROCESSING; FUNGAL CONTAMINATION; FUNGAL GENE; GENE SEQUENCE; MOLECULAR DYNAMICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PENICILLIUM; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION;

ASPERGILLUS; FOOD CONTAMINATION; FOOD MICROBIOLOGY; GENES, FUNGAL; MYCOLOGICAL TYPING TECHNIQUES; MYCOTOXINS; OCHRATOXINS; PENICILLIUM; POLYMERASE CHAIN REACTION;

ASPERGILLUS; ASPERGILLUS CARBONARIUS; ASPERGILLUS OCHRACEUS; FUNGI; PENICILLIUM; PENICILLIUM NORDICUM; PENICILLIUM VERRUCOSUM; TRITICUM AESTIVUM; VITIS SP.;

EID: 19444363108     PISSN: 0265203X     EISSN: None     Source Type: Journal    
DOI: 10.1080/02652030500058452     Document Type: Article

References (64)

1. Abarca ML, Accensi F, Bragulat MR, Castellá G, Cabañes FJ. 2003. Aspergillus carbonarius as the main source of ochratoxin A contamination in dried vine fruits from the Spanish market. Journal of Food Protection 66:504-506.
2. Alexandrakis G, Sears M, Gloor P. 1998. Postmortem diagnosis of Fusarium panophthalmitis by the polymerase chain reaction. American Journal of Ophthalmology 121:221-223.
3. Aoki T, O'Donnell K. 1999. Morphological and molecular characterization of Fusarium pseudograminearum sp. nov, formerly recognized as the group 1 population of F. graminearum. Mycologia 91:597-609.
4. Battilani P, Pietri A, Bertuzzi T, Languisco L, Giorni P, Kozakiewicz Z. 2003. Occurrence of ochratoxin A-producing fungi in grapes grown in Italy. Journal of Food Protection 66:633-636.
5. Bennett JW, Klich M. 2003. Mycotoxins. Clinical Microbiology Reviews 16:497-516.
6. Bingle LEH, Simpson TJ, Lazarus CM. 1999. Ketosynthase domain probes identify two subclasses of fungal polyketide synthase genes. Fungal Genetics and Biology 26:209-223.
7. Bluhm BH, Flaherty JE, Cousin MA, Woloshuk CP. 2002. Multiplex polymerase chain reaction assay for the differential detection of trichothecene- and fumonisin-producing species of Fusarium in cornmeal. Journal of Food Protection 65: 1955-1961.
8. Bogs C, Battilani P, Geisen R. 2005. Development of a molecular detection and differentiation system for ochratoxin A-producing Penicillium species and its application to analyse the occurrence of P. nordicum in fermented meats. International Journal of Food Microbiology (submitted).
9. Castella G, Larsen TO, Cabañes FJ, Schmidt H, Alboresi A, Niessen L, Färber P, Geisen R. 2002. Molecular characterization of ochratoxin A producing strains of the genus Penicillium. Systematic and Applied Microbiology 25:74-83.
10. Chelkowski J. 1991. Preface and introduction. In: Chelkowski J, editor, Cereal grain mycotoxins, fungi and quality in drying and storage. Amsterdam: Elsevier. pp I-XX.
11. Delacruz L, Bach PH. 1990. The role of ochratoxin A metabolism and biochemistry in animal and human nephropathy. Journal of Biopharmaceutical Science 1:277-304.
12. Edwards SG, Pirgozliev SR, Hare MC, Jenkinson P. 2001. Quantification of trichothecene-producing Fusarium species in harvested grain by competitive PCR to determine efficacies of fungicides against Fusarium head blight of winter wheat. Applied Environmental Microbiology 67:1575-1580.
13. Färber P, Geisen R. 2004. Analysis of differentially expressed ochratoxin A biosynthesis genes of Penicillium nordicum. European Journal of Plant Pathology 110:661-669.
14. Feng GH, Leonard TJ. 1998. Culture conditions control expression of the genes for aflatoxin and sterigmatocystin biosynthesis in Aspergillus parasiticus and A. nidulans. Applied and Environmental Microbiology 64:2275-2277.
15. Ferreira NP, Pitout MJ. 1969. The biogenesis of ochratoxin. Journal of the Suid Afrikaans Chemical Institute 22:1-8.
16. Frisvad JC, Filtenborg O, Lund F, Thrane U. 1992a. New selective media for the detection of toxigenic fungi in cereal products, meat and cheese. In: Samson RA, Hocking AD, Pitt JI, King AD, editors. Modern methods in food mycology. Amsterdam: Elsevier. pp 275-284.
17. Frisvad JC, Filtenborg O, Lund F, Thrane U. 1992b. Collaborative study on media for detecting and enumerating toxigenic Penicillium and Aspergillus species. In: Samson RA, Hocking AD, Pitt JI, King AD, editors. Modern methods in food mycology. Amsterdam: Elsevier. pp 255-261.
18. Geisen R. 1996. A multiplex PCR reaction for the detection of aflatoxin and sterigmatocystin producing fungi. Systematic and Applied Microbiology 19:388-392.
19. Geisen R. 2004. Molecular monitoring of environmental conditions influencing the induction of ochratoxin A biosynthesis genes in Penicillium nordicum. Molecular Nutrition and Food Research 48:532-540.
20. Geisen R. Mayer Z, Karolewiez A, Färber P. 2004. Development of a real time PCR system for detection of Penicillium nordicum and for monitoring ochratoxin A production in foods by targeting the ochratoxin polyketide synthase gene. Systematic and Applied Microbiology 27: 501-507.
21. Karolewiez A, Färber P, Geisen R. 2003. Construction of a gene bank of the ochratoxinogenic species Penicillium nordicum and characterization of lambda clones carrying ochratoxin biosynthetic genes. In: 1st FEMS Congress of European Microbiologists Abstract Book. Ljubljana: Federation of European Microbiological Societies (FEMS) vol. 1. p 468.
22. González Jaén MT, Mirete S, Patino B, López-Errasquín E, Vázquez C. 2004. Genetic markers for the analysis of variability and for production of specific diagnostic sequences in fumonisin-producing strains of Fusarium verticillioides. European Journal of Plant Pathology 110:525-532.
23. Hamamoto H, Hasegawa K, Nakaune R, Lee YJ, Akutsu K, Hibi T. 2001. PCR-based detection of sterol demethylation inhibitor-resistant strains of Penicillium digitatum. Pest Management Science 57:839-843.
24. Haugland RA, Vesper SJ. 2000. Method for identifying and quantifying specific fungi and bacteria. Patent 6,387,652, 14 May 2002. Washington, DC: US Patent and Trademark Office.
25. Hocking AD, Pitt JI. 1980. Dichloran-glycerol medium for enumeration of xerophilic fungi from low moisture foods. Applied and Environmental Microbiology 39:488-492.
26. Huff JE. 1991. Carcinogenicity of ochratoxin A in experimental animals. In: Castegnaro M, Plestina R, Dirheimer G, Chernozemsky N, Bartsch H, editors. Mycotoxins, endemic nephropathy and urinary tract tumors. Lyon: IARC. pp 229-244.
27. Huff WE, Hamilton PB. 1979. Mycotoxins - their biosynthesis in fungi: ochratoxins - metabolites of combined pathways. Journal of Food Protection 42:815-820.
28. King AD, Hocking AD, Pitt JI. 1979. Dichloran-rose bengal medium for enumeration of molds from foods. Applied and Environmental Microbiology 37:959-964.
29. Knoll S, Mulfinger S, Niessen L, Vogel RF. 2002. Rapid preparation of Fusarium DNA from cereals for diagnostic PCR using sonification and an extraction kit. Plant Pathology 51:728-734.
30. Kuiper-Goodman T, Scott PM. 1989. Risk assessment of the mycotoxin ochratoxin A. Biomedical and Environmental Sciences 2:179-248.
31. Larsen TO, Svendsen A, Smedsgaard J. 2001. Biochemical characterization of ochratoxin A-producing strains of the genus Penicillium. Applied and Environmental Microbiology 67:3630-3635.
32. Lee T, Oh DW, Kim HS, Lee J, Kim YH, Yun SH, Lee YW. 2001. Identification of deoxynivalenol- and nivalenol-producing chemotypes of Gibberella zeae by using PCR. Applied and Environmental Microbiology 67:2966-2972.
33. Liang, P, Pardee AB. 1992. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 257:967-971.
34. Marek P, Annamalai T, Venkitanarayanan K. 2003. Detection of Penicillium expansum by polymerase chain reaction. International Journal of Food Microbiology 89:139-144.
35. Martins ML, Martins HM, Gimeno A. 2003. Incidence of microflora and of ochratoxin A in green coffee beans (Coffea arabica). Food Additives and Contaminants 20:1127-1131.
36. Möller EM, Bahnweg G, Sandermann H, Geiger HH. 1992. A simple and efficient protocol for isolation of high molecular weight DNA from filamentous fungi, fruit bodies, and infected plant tissues. Nucleic Acids Research 20:6115-6116.
37. Mühlencoert E. 2004. Ochratoxin A production by Aspergillus ochraceus. Thesis, Technical University, Munich.
38. Mühlencoert E, Mayer I, Zapf MW, Vogel RF, Niessen L. 2004. Production of ochratoxin A by Aspergillus ochraccus. European Journal of Plant Pathology 110:651-659.
39. Niessen L, Vogel RF. 1997. Detection of Fusarium graminearum using GaoA-targeted primers. Systematic and Applied Microbiology 20:111-123.
40. Niessen L, Vogel RF. 1998. Group specific PCR-detection of potential trichothecene-producing Fusarium species in pure cultures and cereal samples. Systematic and Applied Microbiology 21:618-631.
41. Northold MD. 1979. The effect of water activity and temperature on the production of some mycotaxins. PhD thesis, University of Wageningen.
42. Northold MD, Frisvad JC, Samson RA. 1995. Occurrence of food-borne fungi and factors for growth. In: Samson RA, Van Reenen-Hoekstra ES, editors. Introduction to Food-Borne Fungi. Delft: Centraalbureau voor Schimmelcultures. pp 243-250.
43. O'Callaghan JO, Caddick MX, Dobson ADW. 2003. A polyketide synthase gene required for ochratoxin A biosynthesis in Aspergillus ochraceus. Microbiology 149:3485-3491.
44. Pardo E, Marín S, Ramos AJ, Sanchis V. 2004. Occurrence of ochratoxigenic fungi and ochratoxin A in green coffee from different origins. Food Science and Technology 10:45-50.
45. Paterson RRM, Archer S, Kozakiewicz Z, Lea A, Locke T, O'Grady E. 2000. A gene probe for the patulin metabolic pathway with potential for use in patulin and novel disease control. Biocontrol Science and Technology 10:509-512.
46. Pelegrinelli-Fungaro MH, Vissoto PC, Sartori D, Vioas-Boas LA, Furlaneto MC, Taniwaki MH. 2004. A molecular method for detection of Aspergillus carbonarius in coffee beans. Current Microbiology 49:123-127.
47. Perrone G, Susca A, Stea G, Mulè G. 2004. PCR assay for identification of Aspergillus carbonarius and Aspergillus japonicus. European Journal of Plant Pathology 110:641-649.
48. Petzinger E, Ziegler K. 2000. Ochratoxin A from a toxicological perspective. Journal of Veterinary and Pharmacological Therapy 23:91-98.
49. Schmidt H, Bannier M, Vogel RF, Niessen L. 2004a. Detection and quantification of Aspergillus ochraceus in green coffee by PCR. Letters in Applied Microbiology 38:464-469.
50. Schmidt H, Ehrmann M, Vogel RF, Taniwaki MH, Niessen L. 2003. Molecular typing of Aspergillus ochraceus and construction of species specific SCAR-primers based on AFLP. Systematic and Applied Microbiology 26:434-438.
51. Schmidt H, Taniwaki MH, Vogel RF, Niessen L. 2004b. Utilization of AFLP markers for PCR-based identification of Aspergillus carbonarius and indication of its presence in green coffee samples. Journal of Applied Microbiology 97:899-909.
52. Schnerr H, Niessen L, Vogel RF. 2001. Real time detection of the tri5 gene in Fusarium species by LightCycler™-PCR using SYBR Green I for continuous fluorescence monitoring. International Journal of Food Microbiology 71:53-61.
53. Schnerr H, Vogel RF, Niessen L. 2002. Correlation between DNA of trichothecene-producing Fusarium species and deoxynivalenol concentrations in wheat-samples. Letters in Applied Microbiology 35:121-125.
54. Serra R, Abrunhosa L, Kozakievicz Z, Venancio A. 2003. Black Aspergillus species as ochratoxin A producers in Portuguese wine grapes. International Journal of Food Microbiology 88: 63-68.
55. Shapira R, Paster N, Eyal O, Menasherov M, Mett A, Salomon R. 1996. Detection of aflatoxinogenic molds in grains by PCR. Applied and Environmental Microbiology 62:3270-3273.
56. Steyn PS. 1993. Ochratoxin A: its chemistry, conformation and biosynthesis. In: Creppy EE, Castegnaro M, Dirheimer G, editors. Human ochratoxicosis and its pathologies. London: John Libbey. Vol. 231. pp 51-58.
57. Steyn PS, Holzapfel WH. 1970. The biosynthesis of the ochratoxins, metabolites of Aspergillus ochraceus. Phytochemistry 9:1977-1983.
58. Sweeney M, Dobson ADW. 1999. Molecular biology of mycotoxin biosynthesis. FEMS Microbiology Letters 175:149-163.
59. Tang CM, Holden DW, Aufauvre-Brown A, Cohen J. 1993. The detection of Aspergillus spp. by the polymerase chain reaction and its evaluation in bronchoalveolar lavage fluid. American Review of Respiratory Disease 148:1313-1317.
60. Taniwaki MH, Pitt JI, Teixeira AA, Imanaka BT. 2003. The source of ochratoxin A in Brazilian coffee and its formation in relation to processing methods. International Journal of Food Microbiology 82:173-179.
61. Tjamos SE, Antoniou PP, Kazantzidou, A, Antonopoulos DF, Papageorgiou, I, Tjamos EC. 2004. Aspergillus niger and Aspergillus carbonarius in Corinth raisin and wine-producing vineyards in Greece: population composition, Ochratoxin A production and chemical control. Journal of Phytopathology (Berlin) 152:250-255.
62. Van der Merwe KJ, Steyn PS, Fourie LF, Scott DB, Theron JJ. 1965. Ochratoxin A, a toxic metabolite produced by Aspergillus ochraceus Wilh. Nature 205:1112-1113.
63. Vos P, Hogers R, Bleeker M, Reijans M, Van de Lee T, Hornes M, Frijters A, Pot J, Peleman J, Kuiper M, Zabeau M. 1995. AFLP: a new technique for DNA fingerprinting. Nucleic Acids Research 23:4407-4414.
64. Wei RD, Strong FM, Smalley EB. 1971. Incorporation of chlorine-36 into ochratoxin A. Applied Microbiology 22:276-277.