Down-regulation of Galα(1,3)Gal expression by α1,2 fucosyltransferase: Further characterization of α1,2-fucosyltransferase transgenic mice

Transplantation

Volumn 64, Issue 3, 1997, Pages 495-500

  Cohney, Shlomo ^a   Mckenzie, Ian F C ^a   Patton, Katherine ^a   Prenzoska, Julijana ^a   Ostenreid, Karen ^a   Fodor, William L ^b   Sandrin, Mauro S ^a  

^a AUSTIN RESEARCH INSTITUTE   (Australia)

^b ALEXION PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; FUCOSYLTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPLEMENT DEPENDENT CYTOTOXICITY; CONTROLLED STUDY; DOWN REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION; TRANSGENE; TRANSGENIC MOUSE; XENOTRANSPLANTATION;

ABO BLOOD-GROUP SYSTEM; ANIMALS; DISACCHARIDES; DOWN-REGULATION; FEMALE; FUCOSYLTRANSFERASES; GENE EXPRESSION; HEMAGGLUTININS; HUMANS; LECTINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PLANT LECTINS;

EID: 0030742322     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199708150-00020     Document Type: Article

References (26)

1. Sandrin MS, McKenzie IFC. Galα(1,3)Gal, the major xenoantigen(s) recognised in pigs by human natural antibodies. Immunol Rev 1994; 141: 169.
2. Sandrin MS, Vaughan HA, Dabkowski PL, McKenzie IFC. Anti-pig IgM antibodies in human serum reacts predominantly with Galα(1,3)Gal epitopes. Proc Natl Acad Sci USA 1993; 90: 11391.
3. Sandrin MS, Vaughan HA, McKenzie IFC. Identification of Galα(1,3)Gal as the major epitope for pig-to-human vascularised xenografts. Transplant Rev 1994; 8: 134.
4. Cooper DK, Koren E, Oriol R. Oligosaccharides and discordant xenotransplantation. Immunol Rev 1994; 141: 31.
5. Cooper DK, Good AH, Koren E, et al. Identification of alpha-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: relevance to discordant xenografting in man. Transpl Immunol 1993; 1: 198.
6. Good AH, Cooper DKC, Malcolm AJ, et al. Identification of carbohydrate structures that bind human antiporcine antibodies: implications for discordant xenografting in humans. Transplant Proc 1992; 24: 559.
7. Galili U, Clark MR, Shohet SB, Buehler J, Macher BA. Evolutionary relationship between the natural anti-Gal antibody and the Galα1-3Gal epitope in primates. Proc Natl Acad Sci USA 1987; 84: 1369.
8. Galili U, Shohet SB, Korbin E, Stults CLM, Macher BA. Man, apes and Old World monkeys differ from other mammals in the expression of the α-galactosyl epitopes on nucleated cells. J Biol Chem 1988; 263: 17755.
9. Thall AD, Maly P, Lowe JB. Oocyte Galα1,3Gal epitopes implicated in sperm adhesion to the zona pellucida glycoprotein ZP3 are not required for fertilization in the mouse. J Biol Chem 1995; 270: 21437.
10. Tearle RG, Tange MJ, Zannettino ZL, et al. The α-1,3-galacto-syltransferase knockout mouse: implications for xenotransplantation. Transplantation 1996; 61: 13.
11. Sandrin MS, Fodor WL, Mouhtouris E, et al. Enzymatic remodeling of the carbohydrate surface of a xenogenic cell substantially reduces human antibody binding and complement-mediated cytolysis. Nature Med 1995; 1: 1261.
12. Weiss EH, Golden L, Zakut R, et al. The DNA sequence of the H-2Kb gene: evidence for gene conversion as a mechanism for the generation of polymorphism in histocompatibility antigens. EMBO J 1983; 2: 453.
13. Matsumoto I, Osawa T. Purification and characterization of an anti-H(O) phytohemagglutinin of ulex europaeus. Biochim Biophys Acta 1969; 194; 180.
14. Hogarth PM, Hibbs ML, Bonadonna L, Scott BM, Witort E, McKenzie IFC. The murine FcR for IgG (Ly17): molecular cloning and specificity. Immunogenetics 1987; 26: 161.
15. Hayes CE, Goldstein IJ. An a-D-galactosyl-binding lectin from Bandeiraea simplicifolia seeds. J Biol Chem 1974; 249: 1904.
16. Sandrin MS, Vaughan HA, McKenzie IFC, Tait BD, Parish CR. The human Ia system: definition and characterization by xenogeneic antisera. Immunogenetics 1979; 8: 185.
17. Vaughan HA, Loveland BE, Sandrin MS. Gal α(1,3)Gal is the major xenoepitope expressed on pig endothelial cells recognized by naturally occurring cytotoxic human antibodies. Transplantation 1994; 58(8): 879.
18. Cattoreti G, Becker MH, Key G, et al. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB1 and MIB3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J Pathol 1992; 168: 357.
19. Gown AM, deWever N, Battifora H. Microwave-based antigenic , unmasking, a revolutionary new technique for routine immunohistochemistry. Immunohistochemistry 1993; 1: 256.
20. Shan-Rong S, Key M, Kalra K. Antigen retrieval in formalinfixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. J Histochem Cytochem 1991; 39: 741.
21. McKenzie IFC, Koulmanda M, Mandel T, King P-X, Sandrin MS. Comparative studies of the major xenoantigen Galα(1,3)Gal in pigs and mice. Transplant Proc 1995; 27: 247.
22. Peters BP, Goldstein IJ. The use of fluorescein-conjugated Bandeiraea siplicifolia B4-isolectin as a histochemical reagent for the detection of α-D-galactpyranosyl groups. Exp Cell Res 1979; 120: 321.
23. Larsen RD, Ernst LK, Nair RP, Lowe JB. Molecular cloning, sequence, and expression of a human GDP-L-fucose:β-D-galactoside 2-α-L-fucosyltransferase cDNA that can form the H blood group antigen. Proc Natl Acad Sci USA 1990; 87: 6674.
24. Chen C-G, Fisicaro N, Shinkel TA, et al. Reduction in Gal-α-1,3-Gal epitope expression in transgenic mice expressing human H-transferase. Xenotransplantation 1996; 3: 69.
25. Koike C, Kannagi R, Takuma Y, et al. Introduction of α1,2-fucosyltransferase and its effect on α-Gal epitopes in transgenic pig. Xenotransplantation 1996; 3: 81.
26. Sharma A, Okabe J, Birch P, et al. Reduction in the level of Galα(1,3)Gal in transgenic mice and pigs by expression of an α(1,2)fucosyltransferase. Proc Natl Acad Sci USA 1996; 93: 7190.