-
1
-
-
0043240182
-
Ovarian cancer: Strategies for overcoming resistance to chemotherapy
-
Agarwal R, Kaye SB (2003) Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat Rev Cancer 7:502
-
(2003)
Nat Rev Cancer
, vol.7
, pp. 502
-
-
Agarwal, R.1
Kaye, S.B.2
-
2
-
-
0036358635
-
Arsenic trioxide in multiple myeloma: Rationale and future directions
-
Anderson KC, Boise LH, Louie R, Waxman S (2002) Arsenic trioxide in multiple myeloma: rationale and future directions. Cancer J 8:12
-
(2002)
Cancer J
, vol.8
, pp. 12
-
-
Anderson, K.C.1
Boise, L.H.2
Louie, R.3
Waxman, S.4
-
3
-
-
0034637481
-
Identification, characterization, and crystal structure of the omega class glutathione transferases
-
Board PG, Coggan M, Chelvanayagam G, Easteal S, Jermiin LS, Schulte GK, Danley DE, Hoth LR, Griffor MC, Kamath AV, Rosner MH, Chrunyk BA, Perregaux DE, Gabel CA, Geoghegan KF, Pandit J (2000) Identification, characterization, and crystal structure of the omega class glutathione transferases. J Biol Chem 275:24798
-
(2000)
J Biol Chem
, vol.275
, pp. 24798
-
-
Board, P.G.1
Coggan, M.2
Chelvanayagam, G.3
Easteal, S.4
Jermiin, L.S.5
Schulte, G.K.6
Danley, D.E.7
Hoth, L.R.8
Griffor, M.C.9
Kamath, A.V.10
Rosner, M.H.11
Chrunyk, B.A.12
Perregaux, D.E.13
Gabel, C.A.14
Geoghegan, K.F.15
Pandit, J.16
-
4
-
-
0010740572
-
3 induces NB4 cell apoptosis with down regulation of bcl-2 expression and modulation of PML-RAR alpha/PML proteins
-
3 induces NB4 cell apoptosis with down regulation of bcl-2 expression and modulation of PML-RAR alpha/PML proteins. Blood 88:1052
-
(1996)
Blood
, vol.88
, pp. 1052
-
-
Chen, G.Q.1
Zhu, J.2
Shi, X.G.3
Ni, J.H.4
Zhong, H.J.5
Si, G.Y.6
Jin, X.L.7
Tang, W.8
Li, X.S.9
Xong, S.M.10
Shen, Z.X.11
Sun, G.L.12
Ma, J.13
Zhang, P.14
Zhang, T.D.15
Gazin, C.16
Naoe, T.17
Chen, S.J.18
Wang, Z.Y.19
Chen, Z.20
more..
-
5
-
-
0037447171
-
Methylated metabolites of arsenic trioxide are more potent than arsenic trioxide as apoptotic but not differentiation inducers in leukemia and lymphoma cells
-
Chen GQ, Zhou L, Styblo M, Walton F, Jing Y, Weinberg R, Chen Z, Waxman S (2003) Methylated metabolites of arsenic trioxide are more potent than arsenic trioxide as apoptotic but not differentiation inducers in leukemia and lymphoma cells. Cancer Res 63:1853
-
(2003)
Cancer Res
, vol.63
, pp. 1853
-
-
Chen, G.Q.1
Zhou, L.2
Styblo, M.3
Walton, F.4
Jing, Y.5
Weinberg, R.6
Chen, Z.7
Waxman, S.8
-
6
-
-
0035283244
-
Incidence of transitional cell carcinoma and arsenic in drinking water: A follow-up study of 8,102 residents in an arseniasis-endemic area in Northeastern Taiwan
-
Chiou HY, Chiou ST, Hsu YH, Chou YL, Chin-Hsiao Tseng CH, Wei ML, Chen CJ (2001) Incidence of transitional cell carcinoma and arsenic in drinking water: a follow-up study of 8,102 residents in an arseniasis-endemic area in Northeastern Taiwan. Am J Epidemiol 153:411
-
(2001)
Am J Epidemiol
, vol.153
, pp. 411
-
-
Chiou, H.Y.1
Chiou, S.T.2
Hsu, Y.H.3
Chou, Y.L.4
Chin-Hsiao Tseng, C.H.5
Wei, M.L.6
Chen, C.J.7
-
7
-
-
0032933610
-
Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system
-
Dai J, Weinberg RS, Waxman S, Jing Y (1999) Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system. Blood 93:268
-
(1999)
Blood
, vol.93
, pp. 268
-
-
Dai, J.1
Weinberg, R.S.2
Waxman, S.3
Jing, Y.4
-
8
-
-
0037851760
-
Glutathione depletion overcomes resistance to arsenic trioxide in arsenic-resistant cell lines
-
Davison K, Cote S, Mader S, Miller WH (2003) Glutathione depletion overcomes resistance to arsenic trioxide in arsenic-resistant cell lines. Leukemia 5:931
-
(2003)
Leukemia
, vol.5
, pp. 931
-
-
Davison, K.1
Cote, S.2
Mader, S.3
Miller, W.H.4
-
9
-
-
0036919717
-
Induction of apoptosis in cancer: New therapeutic opportunities
-
Ding HF, Fisher DE (2002) Induction of apoptosis in cancer: new therapeutic opportunities. Ann Med 34:451
-
(2002)
Ann Med
, vol.34
, pp. 451
-
-
Ding, H.F.1
Fisher, D.E.2
-
10
-
-
0016382598
-
Symptoms of X-ray damage to radiosensitive mouse leukemic cells: Asynchronous populations
-
Ehmann UK, Nagasawa H, Petersen DF, Lett JT (1974) Symptoms of X-ray damage to radiosensitive mouse leukemic cells: asynchronous populations. Radiat Res 6:453
-
(1974)
Radiat Res
, vol.6
, pp. 453
-
-
Ehmann, U.K.1
Nagasawa, H.2
Petersen, D.F.3
Lett, J.T.4
-
11
-
-
0036184777
-
Arsenic trioxide cytotoxicity in steroid and chemotherapy-resistant myeloma cell lines: Enhancement of apoptosis by manipulation of cellular redox state
-
Gartenhaus RB, Prachand SN, Paniaqua M, Li Y, Gordon LI (2002) Arsenic trioxide cytotoxicity in steroid and chemotherapy-resistant myeloma cell lines: enhancement of apoptosis by manipulation of cellular redox state. Clin Cancer Res 8:566
-
(2002)
Clin Cancer Res
, vol.8
, pp. 566
-
-
Gartenhaus, R.B.1
Prachand, S.N.2
Paniaqua, M.3
Li, Y.4
Gordon, L.I.5
-
12
-
-
0038346303
-
Difference in uptake and toxicity of trivalent and pentavalent inorganic arsenic in rat heart microvessel endothelial cells
-
Hirano S, Cui X, Li S, Kanno S, Kobayashi Y, Hayakawa T, Shraim A (2003) Difference in uptake and toxicity of trivalent and pentavalent inorganic arsenic in rat heart microvessel endothelial cells. Arch Toxicol 77:305
-
(2003)
Arch Toxicol
, vol.77
, pp. 305
-
-
Hirano, S.1
Cui, X.2
Li, S.3
Kanno, S.4
Kobayashi, Y.5
Hayakawa, T.6
Shraim, A.7
-
13
-
-
0017064979
-
A fluorimetric method for determination of oxidized and reduced glutathione in tissues
-
Hissin PJ, Hilf R (1976) A fluorimetric method for determination of oxidized and reduced glutathione in tissues. Anal Biochem 74:214
-
(1976)
Anal Biochem
, vol.74
, pp. 214
-
-
Hissin, P.J.1
Hilf, R.2
-
14
-
-
0042170060
-
Arsenic trioxide induces apoptosis in cells of MOLT-4 and its daunorubicin-resistant cell line via depletion of intracellular glutathione, disruption of mitochondrial membrane potential and activation of caspase-3
-
Hu XM, Hirano T, Oka K (2003) Arsenic trioxide induces apoptosis in cells of MOLT-4 and its daunorubicin-resistant cell line via depletion of intracellular glutathione, disruption of mitochondrial membrane potential and activation of caspase-3. Cancer Chemother Pharmacol 52:47
-
(2003)
Cancer Chemother Pharmacol
, vol.52
, pp. 47
-
-
Hu, X.M.1
Hirano, T.2
Oka, K.3
-
15
-
-
0036372619
-
Redox potential of GSH/GSSG couple: Assay and biological significance
-
Jones DP (2002) Redox potential of GSH/GSSG couple: assay and biological significance. Methods Enzymol 348:93
-
(2002)
Methods Enzymol
, vol.348
, pp. 93
-
-
Jones, D.P.1
-
16
-
-
0034721764
-
The MRP2/cMOAT transporter and arsenic-glutathione complex formation are required for biliary excretion of arsenic
-
Kala SV, Neely MW, Kala G, Prater CI, Atwood DW, Rice JS, Lieberman MW (2000) The MRP2/cMOAT transporter and arsenic-glutathione complex formation are required for biliary excretion of arsenic. J Biol Chem 275:33404
-
(2000)
J Biol Chem
, vol.275
, pp. 33404
-
-
Kala, S.V.1
Neely, M.W.2
Kala, G.3
Prater, C.I.4
Atwood, D.W.5
Rice, J.S.6
Lieberman, M.W.7
-
17
-
-
1342331929
-
Formation and urinary excretion of arsenic triglutathione and methylarsenic diglutathione
-
Kala SV, Kala G, Prater CI, Sartorelli AC, Lieberman MW (2004) Formation and urinary excretion of arsenic triglutathione and methylarsenic diglutathione. Chem Res Toxicol 17:243
-
(2004)
Chem Res Toxicol
, vol.17
, pp. 243
-
-
Kala, S.V.1
Kala, G.2
Prater, C.I.3
Sartorelli, A.C.4
Lieberman, M.W.5
-
18
-
-
0033582482
-
The cloning and characterization of a new stress response protein. A mammalian member of a family of theta class glutathione S-transferase-like proteins
-
Kodym R, Calkins P, Story M (1999) The cloning and characterization of a new stress response protein. A mammalian member of a family of theta class glutathione S-transferase-like proteins. J Biol Chem 274:5131
-
(1999)
J Biol Chem
, vol.274
, pp. 5131
-
-
Kodym, R.1
Calkins, P.2
Story, M.3
-
19
-
-
0035976997
-
NF-kappaB1 (p50) homodimers contribute to transcription of the bcl-2 oncogene
-
Kurland JF, Kodym R, Story MD, Spurgers KB, McDonnell TJ, Meyn RE (2001) NF-kappaB1 (p50) homodimers contribute to transcription of the bcl-2 oncogene. J Biol Chem 276:45380
-
(2001)
J Biol Chem
, vol.276
, pp. 45380
-
-
Kurland, J.F.1
Kodym, R.2
Story, M.D.3
Spurgers, K.B.4
McDonnell, T.J.5
Meyn, R.E.6
-
20
-
-
0033563729
-
Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore
-
Larochette N, Decaudin D, Jacotot E, Brenner C, Marzo I, Susin SA, Zamzami N, Xie Z, Reed J, Kroemer G (1999) Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore. Exp Cell Res 249:413
-
(1999)
Exp Cell Res
, vol.249
, pp. 413
-
-
Larochette, N.1
Decaudin, D.2
Jacotot, E.3
Brenner, C.4
Marzo, I.5
Susin, S.A.6
Zamzami, N.7
Xie, Z.8
Reed, J.9
Kroemer, G.10
-
21
-
-
0035852735
-
Induction of oxyradicals by arsenic: Implication for mechanism of genotoxicity
-
Liu SX, Athar M, Lippai I, Waldren C, Hei TK (2001) Induction of oxyradicals by arsenic: implication for mechanism of genotoxicity. Proc Natl Acad Sci U S A 98:1643
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 1643
-
-
Liu, S.X.1
Athar, M.2
Lippai, I.3
Waldren, C.4
Hei, T.K.5
-
22
-
-
0038265069
-
Recent advances in understanding apoptosis: New therapeutic opportunities in cancer chemotherapy
-
Makin G, Dive C (2003) Recent advances in understanding apoptosis: new therapeutic opportunities in cancer chemotherapy. Trends Mol Med 6:251
-
(2003)
Trends Mol Med
, vol.6
, pp. 251
-
-
Makin, G.1
Dive, C.2
-
23
-
-
0038199888
-
Drug resistance in cancer: A multifactorial problem
-
Mattern J (2003) Drug resistance in cancer: a multifactorial problem. Anticancer Res 2C:1769
-
(2003)
Anticancer Res
, vol.2 C
, pp. 1769
-
-
Mattern, J.1
-
24
-
-
0030754701
-
Resistance to radiation-induced apoptosis in bcl-2-expressing cells is reversed by depleting cellular thiols
-
Mirkovic N, Voehringer DW, Story MD, McConkey DJ, McDonnell TJ, Meyn RE (1997) Resistance to radiation-induced apoptosis in bcl-2-expressing cells is reversed by depleting cellular thiols. Oncogene 15:1461
-
(1997)
Oncogene
, vol.15
, pp. 1461
-
-
Mirkovic, N.1
Voehringer, D.W.2
Story, M.D.3
McConkey, D.J.4
McDonnell, T.J.5
Meyn, R.E.6
-
25
-
-
0038610951
-
Direct activation of the apoptosis machinery as a mechanism to target cancer cells
-
Nguyen JT, Wells JA (2003) Direct activation of the apoptosis machinery as a mechanism to target cancer cells. Proc Natl Acad Sci U S A 100:7533
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 7533
-
-
Nguyen, J.T.1
Wells, J.A.2
-
26
-
-
0036104528
-
A major human arsenic metabolite, dimethylarsinic acid, requires reduced glutathione to induce apoptosis
-
Sakurai T, Qu W, Sakurai MH, Waalkes MP (2002) A major human arsenic metabolite, dimethylarsinic acid, requires reduced glutathione to induce apoptosis. Chem Res Toxicol 5:629
-
(2002)
Chem Res Toxicol
, vol.5
, pp. 629
-
-
Sakurai, T.1
Qu, W.2
Sakurai, M.H.3
Waalkes, M.P.4
-
27
-
-
0036118319
-
Apoptosis and chemoresistance in transgenic cancer models
-
Schmitt CA, Lowe SW (2002) Apoptosis and chemoresistance in transgenic cancer models. J Mol Med 80:137
-
(2002)
J Mol Med
, vol.80
, pp. 137
-
-
Schmitt, C.A.1
Lowe, S.W.2
-
28
-
-
0037972159
-
Induction of oxidative DNA damage by arsenite and its trivalent and pentavalent methylated metabolites in cultured human cells and isolated DNA
-
Schwerdtle T, Walter I, Mackiw I, Hartwig A (2003) Induction of oxidative DNA damage by arsenite and its trivalent and pentavalent methylated metabolites in cultured human cells and isolated DNA. Carcinogenesis 24:967
-
(2003)
Carcinogenesis
, vol.24
, pp. 967
-
-
Schwerdtle, T.1
Walter, I.2
Mackiw, I.3
Hartwig, A.4
-
29
-
-
0000531696
-
Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells
-
Shao W, Fanelli M, Ferrara FF, Riccioni R, Rosenauer A, Davison K, Lamph WW, Waxman S, Pelicci PG, Lo Coco F, Avvisati G, Testa U, Peschle C, Gambacorti-Passerini C, Nervi C, Miller WH Jr (1998) Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells. J Natl Cancer Inst 90:124
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 124
-
-
Shao, W.1
Fanelli, M.2
Ferrara, F.F.3
Riccioni, R.4
Rosenauer, A.5
Davison, K.6
Lamph, W.W.7
Waxman, S.8
Pelicci, P.G.9
Lo Coco, F.10
Avvisati, G.11
Testa, U.12
Peschle, C.13
Gambacorti-Passerini, C.14
Nervi, C.15
Miller Jr., W.H.16
-
30
-
-
0032054940
-
Marked increase in bladder and lung cancer mortality in a region of Northern Chile due to arsenic in drinking water
-
Smith AH, Goycolea M, Haque R, Biggs ML (1998) Marked increase in bladder and lung cancer mortality in a region of Northern Chile due to arsenic in drinking water. Am J Epidemiol 147:660
-
(1998)
Am J Epidemiol
, vol.147
, pp. 660
-
-
Smith, A.H.1
Goycolea, M.2
Haque, R.3
Biggs, M.L.4
-
31
-
-
0032487923
-
Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide
-
Soignet SL, Maslak P, Wang ZG, Jhanwar S, Calleja E, Dardashti LJ, Corso D, DeBlasio A, Gabrilove J, Scheinberg DA, Pandolfi PP, Warrell RP Jr (1998) Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide. N Engl J Med 339:1341
-
(1998)
N Engl J Med
, vol.339
, pp. 1341
-
-
Soignet, S.L.1
Maslak, P.2
Wang, Z.G.3
Jhanwar, S.4
Calleja, E.5
Dardashti, L.J.6
Corso, D.7
DeBlasio, A.8
Gabrilove, J.9
Scheinberg, D.A.10
Pandolfi, P.P.11
Warrell Jr., R.P.12
-
32
-
-
0034004681
-
Arsenic in drinking water and bladder cancer
-
Steinmaus C, Moore L, Hopenhayn-Rich C, Biggs ML, Smith AH (2000) Arsenic in drinking water and bladder cancer. Cancer Invest 18:174
-
(2000)
Cancer Invest
, vol.18
, pp. 174
-
-
Steinmaus, C.1
Moore, L.2
Hopenhayn-Rich, C.3
Biggs, M.L.4
Smith, A.H.5
-
34
-
-
0028575336
-
Radiation-induced apoptosis in sensitive and resistant cells isolated from a mouse lymphoma
-
Story MD, Voehringer DW, Malone CG, Hobbs ML, Meyn RE (1994) Radiation-induced apoptosis in sensitive and resistant cells isolated from a mouse lymphoma. Int J Radiat Biol 66:659
-
(1994)
Int J Radiat Biol
, vol.66
, pp. 659
-
-
Story, M.D.1
Voehringer, D.W.2
Malone, C.G.3
Hobbs, M.L.4
Meyn, R.E.5
-
35
-
-
0032831848
-
Bcl-2 expression correlates with apoptosis induction but not tumor growth delay in transplantable murine lymphomas treated with different chemotherapy drugs
-
Story MD, Mirkovic N, Hunter N, Meyn RE (1999) Bcl-2 expression correlates with apoptosis induction but not tumor growth delay in transplantable murine lymphomas treated with different chemotherapy drugs. Cancer Chemother Pharmacol 44:367
-
(1999)
Cancer Chemother Pharmacol
, vol.44
, pp. 367
-
-
Story, M.D.1
Mirkovic, N.2
Hunter, N.3
Meyn, R.E.4
-
36
-
-
0032848668
-
Modulation of apoptosis and enhancement of chemosensitivity by decreasing cellular thiols in a mouse B-cell lymphoma cell line that overexpresses bcl-2
-
Story MD, Meyn RE (1999) Modulation of apoptosis and enhancement of chemosensitivity by decreasing cellular thiols in a mouse B-cell lymphoma cell line that overexpresses bcl-2. Cancer Chemother Pharmacol 44:362
-
(1999)
Cancer Chemother Pharmacol
, vol.44
, pp. 362
-
-
Story, M.D.1
Meyn, R.E.2
-
37
-
-
0031671479
-
ASTRO research fellowship: The role of BCL-2 and glutathione in an antioxidant pathway to prevent radiation-induced apoptosis
-
Vlachaki MT, Meyn RE (1998) ASTRO research fellowship: the role of BCL-2 and glutathione in an antioxidant pathway to prevent radiation-induced apoptosis. Int J Radiat Oncol Biol Phys 42:185
-
(1998)
Int J Radiat Oncol Biol Phys
, vol.42
, pp. 185
-
-
Vlachaki, M.T.1
Meyn, R.E.2
-
38
-
-
0029982119
-
Arsenite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species
-
Wang TS, Kuo CF, Jan KY, Huang H (1996) Arsenite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species. J Cell Physiol 169:256
-
(1996)
J Cell Physiol
, vol.169
, pp. 256
-
-
Wang, T.S.1
Kuo, C.F.2
Jan, K.Y.3
Huang, H.4
-
39
-
-
0034663032
-
Arsenic trioxide induces dose- And time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis
-
Warrell PJ, Rafii S (2000) Arsenic trioxide induces dose- and time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis. Blood 96:1525
-
(2000)
Blood
, vol.96
, pp. 1525
-
-
Warrell, P.J.1
Rafii, S.2
-
40
-
-
0035038845
-
History of the development of arsenic derivatives in cancer therapy
-
Waxman S, Anderson KC (2001) History of the development of arsenic derivatives in cancer therapy. Oncologist 6 [Suppl 2]:3
-
(2001)
Oncologist
, vol.6
, Issue.2 SUPPL.
, pp. 3
-
-
Waxman, S.1
Anderson, K.C.2
-
41
-
-
0032718622
-
Arsenic trioxide sensitivity is associated with low level of glutathione in cancer cells
-
Yang CH, Kuo ML, Chen JC, Chen YC (1999) Arsenic trioxide sensitivity is associated with low level of glutathione in cancer cells. Br J Cancer 81:796
-
(1999)
Br J Cancer
, vol.81
, pp. 796
-
-
Yang, C.H.1
Kuo, M.L.2
Chen, J.C.3
Chen, Y.C.4
-
43
-
-
0034873709
-
Human monomethylarsonic acid (MMA(V)) reductase is a member of the glutathione-S-transferase superfamily
-
Zakharyan RA, Sampayo-Reyes A, Healy SM, Tsaprailis G, Board PG, Liebler DC, Aposhian HV (2001) Human monomethylarsonic acid (MMA(V)) reductase is a member of the glutathione-S-transferase superfamily. Chem Res Toxicol 8:1051
-
(2001)
Chem Res Toxicol
, vol.8
, pp. 1051
-
-
Zakharyan, R.A.1
Sampayo-Reyes, A.2
Healy, S.M.3
Tsaprailis, G.4
Board, P.G.5
Liebler, D.C.6
Aposhian, H.V.7
-
44
-
-
0001837016
-
Arsenic trioxide treated 72 cases of acute promyelocytic leukemia
-
Zhang P, Wang SY, Hu LH, Shi FD, Qui FD, Hong RJ, Han XY (1996) Arsenic trioxide treated 72 cases of acute promyelocytic leukemia. Chin J Hematol 17:58
-
(1996)
Chin J Hematol
, vol.17
, pp. 58
-
-
Zhang, P.1
Wang, S.Y.2
Hu, L.H.3
Shi, F.D.4
Qui, F.D.5
Hong, R.J.6
Han, X.Y.7
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