메뉴 건너뛰기




Volumn 63, Issue 8, 2003, Pages 1853-1859

Methylated metabolites of arsenic trioxide are more potent than arsenic trioxide as apoptotic but not differentiation inducers in leukemia and lymphoma cells

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC TRIOXIDE; ARSINE DERIVATIVE; CACODYLIC ACID; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; IODODIMETHYLARSINE; METHANEARSONIC ACID; METHYLARSINE OXIDE; RETINOIC ACID RECEPTOR ALPHA; UNCLASSIFIED DRUG;

EID: 0037447171     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (97)

References (36)
  • 1
    • 0030324321 scopus 로고    scopus 로고
    • PML, PLZF and NPM genes in the molecular pathogenesis of acute promyelocytic leukemia
    • Pandolfi, P. P. PML, PLZF and NPM genes in the molecular pathogenesis of acute promyelocytic leukemia, Haematologica, 81: 472-82, 1996.
    • (1996) Haematologica , vol.81 , pp. 472-482
    • Pandolfi, P.P.1
  • 2
    • 0025875679 scopus 로고
    • The PML-RAR α fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
    • de The, H., Lavau, C., Marchio, A., Chomienne, C., Degos, L., and Dejean, A. The PML-RAR α fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. Cell. 66: 675-84, 1991.
    • (1991) Cell , vol.66 , pp. 675-684
    • De The, H.1    Lavau, C.2    Marchio, A.3    Chomienne, C.4    Degos, L.5    Dejean, A.6
  • 3
    • 0033561797 scopus 로고    scopus 로고
    • Deconstructing a disease: RARα, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia
    • Melnick, A., and Licht, J. D. Deconstructing a disease: RARα, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia, Blood, 93: 3167-215, 1999.
    • (1999) Blood , vol.93 , pp. 3167-3215
    • Melnick, A.1    Licht, J.D.2
  • 7
    • 0030772260 scopus 로고    scopus 로고
    • Differentiation therapy in acute promyelocytic leukemia: European experience
    • Degos, L. Differentiation therapy in acute promyelocytic leukemia: European experience. J. Cell Physiol., 173: 285-7, 1997.
    • (1997) J. Cell Physiol. , vol.173 , pp. 285-287
    • Degos, L.1
  • 9
    • 0008517022 scopus 로고    scopus 로고
    • Enzymatic methylation of arsenic species and other new approaches to arsenic toxicity
    • Aposhian, H. V. Enzymatic methylation of arsenic species and other new approaches to arsenic toxicity. Annu. Rev. Pharmacol. Toxicol., 37: 397-419, 1997.
    • (1997) Annu. Rev. Pharmacol. Toxicol. , vol.37 , pp. 397-419
    • Aposhian, H.V.1
  • 10
    • 0035341195 scopus 로고    scopus 로고
    • Recent advances in arsenic carcinogenesis: Modes of action, animal model systems, and methylated arsenic metabolites
    • Kitchin, K. T. Recent advances in arsenic carcinogenesis: modes of action, animal model systems, and methylated arsenic metabolites. Toxicol. Appl. Pharmacol., 172: 249-61, 2001.
    • (2001) Toxicol. Appl. Pharmacol. , vol.172 , pp. 249-261
    • Kitchin, K.T.1
  • 11
    • 0035419866 scopus 로고    scopus 로고
    • Determination of trivalent methylated arsenicals in biological matrices
    • Del Razo, L. M., Styblo, M., Cullen, W. R., and Thomas, D. J. Determination of trivalent methylated arsenicals in biological matrices. Toxicol. Appl. Pharmacol., 174: 282-93, 2001.
    • (2001) Toxicol. Appl. Pharmacol. , vol.174 , pp. 282-293
    • Del Razo, L.M.1    Styblo, M.2    Cullen, W.R.3    Thomas, D.J.4
  • 14
    • 0036803041 scopus 로고    scopus 로고
    • The role of biomethylation in toxicity and carcinogenicity of arsenic. A research update
    • Styblo, M., Drobna, Z., Jaspers, I., Lin, S., and Thomas, D. J. The role of biomethylation in toxicity and carcinogenicity of arsenic. A research update. Environ. Health Perspect., 110 SuppL 5: 767-771, 2002.
    • (2002) Environ. Health Perspect. , vol.110 , Issue.SUPPL. 5 , pp. 767-771
    • Styblo, M.1    Drobna, Z.2    Jaspers, I.3    Lin, S.4    Thomas, D.J.5
  • 15
    • 0034974261 scopus 로고    scopus 로고
    • Monomethylarsonous acid (MMAIII) and arsenite: LD50 in hamsters and in vitro inhibition of pyruvate dehydrogenase
    • Petrick, J. S., Jagadish, B., Mash, E. A., and Aposhian, H. V. Monomethylarsonous acid (MMAIII) and arsenite: LD50 in hamsters and in vitro inhibition of pyruvate dehydrogenase. Chem. Res. Toxicol., 14: 651-656, 2001.
    • (2001) Chem. Res. Toxicol. , vol.14 , pp. 651-656
    • Petrick, J.S.1    Jagadish, B.2    Mash, E.A.3    Aposhian, H.V.4
  • 17
    • 0026013478 scopus 로고
    • NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3)
    • Lanotte, M., Martin-Thouvenin, V., Najman, S., Ballerini, P., Valensi, F., and Bergen, R. NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3). Blood, 77: 1080-1086, 1991.
    • (1991) Blood , vol.77 , pp. 1080-1086
    • Lanotte, M.1    Martin-Thouvenin, V.2    Najman, S.3    Ballerini, P.4    Valensi, F.5    Bergen, R.6
  • 18
    • 0010740572 scopus 로고    scopus 로고
    • In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR α/PML proteins
    • Chen, G. Q., Zhu, J., Shi, X. G., Ni, J. H., Zhong, H. J., Si, G. Y., Jin, X. L., Tang, W., Li, X. S., Xong, S. M., Shen, Z. X., Sun, G. L., Ma, J., Zhang, P., Zhang, T. D., Gazin, C., Naoe, T., Chen, S. J., Wang, Z. Y., and Chen, Z. In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR α/PML proteins. Blood, 88: 1052-61, 1996.
    • (1996) Blood , vol.88 , pp. 1052-1061
    • Chen, G.Q.1    Zhu, J.2    Shi, X.G.3    Ni, J.H.4    Zhong, H.J.5    Si, G.Y.6    Jin, X.L.7    Tang, W.8    Li, X.S.9    Xong, S.M.10    Shen, Z.X.11    Sun, G.L.12    Ma, J.13    Zhang, P.14    Zhang, T.D.15    Gazin, C.16    Naoe, T.17    Chen, S.J.18    Wang, Z.Y.19    Chen, Z.20    more..
  • 20
    • 0033568238 scopus 로고    scopus 로고
    • Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide dependent pathway
    • Jing, Y., Dai, J., Cahlmers-Redman, R. M. E., Tatton, W., and Waxman, S. arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide dependent pathway. Blood, 94: 2102-11, 1999.
    • (1999) Blood , vol.94 , pp. 2102-2111
    • Jing, Y.1    Dai, J.2    Cahlmers-Redman, R.M.E.3    Tatton, W.4    Waxman, S.5
  • 21
    • 50849152175 scopus 로고
    • The reaction of methylarsenicals with thiols: Some biological implications
    • Cullen, W. R., McBride, B. C., and Reglinski, J. The reaction of methylarsenicals with thiols: some biological implications. J. Inorganic Biochem., 21: 179-194, 1984.
    • (1984) J. Inorganic Biochem. , vol.21 , pp. 179-194
    • Cullen, W.R.1    McBride, B.C.2    Reglinski, J.3
  • 22
    • 0031022263 scopus 로고    scopus 로고
    • Comparative inhibition of yeast glutathione reductase by arsenicals and arsenothiols
    • Styblo, M., Serves, S. V., Cullen, W. R., and Thomas, D. J. Comparative inhibition of yeast glutathione reductase by arsenicals and arsenothiols. Chem. Res. Toxicol., 10: 27-33, 1997.
    • (1997) Chem. Res. Toxicol. , vol.10 , pp. 27-33
    • Styblo, M.1    Serves, S.V.2    Cullen, W.R.3    Thomas, D.J.4
  • 23
    • 0017367539 scopus 로고
    • Preparation and purification of 74As-labeled arsenate and arsenite for use in biological experiments
    • Reay, P. F., and Asher, C. J. Preparation and purification of 74As-labeled arsenate and arsenite for use in biological experiments. Anal. Biochem., 78: 557-60, 1977.
    • (1977) Anal. Biochem. , vol.78 , pp. 557-560
    • Reay, P.F.1    Asher, C.J.2
  • 24
    • 0029598798 scopus 로고
    • Comparative in vitro methylation of trivalent and pentavalent arsenicals
    • Styblo, M., Yamauchi, H., and Thomas, D. J. Comparative in vitro methylation of trivalent and pentavalent arsenicals. Toxicol. Appl. Pharmacol., 135: 172-8, 1995.
    • (1995) Toxicol. Appl. Pharmacol. , vol.135 , pp. 172-178
    • Styblo, M.1    Yamauchi, H.2    Thomas, D.J.3
  • 25
    • 0029793469 scopus 로고    scopus 로고
    • Alterations in expression, binding to ligand and DNA, and transcriptional activity of rearranged and wild-type retinoid receptors in retinoid-resistant acute promyelocytic leukemia cell lines
    • Rosenauer, A., Raelson, J. V., Nervi, C., Eydoux, P., DeBlasio, A., and Miller, W. H., Jr. Alterations in expression, binding to ligand and DNA, and transcriptional activity of rearranged and wild-type retinoid receptors in retinoid-resistant acute promyelocytic leukemia cell lines. Blood. 88: 2671-82, 1996.
    • (1996) Blood , vol.88 , pp. 2671-2682
    • Rosenauer, A.1    Raelson, J.V.2    Nervi, C.3    Eydoux, P.4    DeBlasio, A.5    Miller W.H., Jr.6
  • 26
    • 0028932963 scopus 로고
    • The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML
    • Borden, K. L., Boddy, M. N., Lally, J., O'Reilly, N. J., Martin, S., Howe, K., Solomon, E., and Freemont, P. S. The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML. EMBO J., 14: 1532-41, 1995.
    • (1995) EMBO J. , vol.14 , pp. 1532-1541
    • Borden, K.L.1    Boddy, M.N.2    Lally, J.3    O'Reilly, N.J.4    Martin, S.5    Howe, K.6    Solomon, E.7    Freemont, P.S.8
  • 29
    • 0035161286 scopus 로고    scopus 로고
    • Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo
    • Jing, Y., Wang, L., Xia, L., Chen, G. Q., Chen, Z., Miller, W. H., and Waxman, S. Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo. Blood, 97: 264-9, 2001.
    • (2001) Blood , vol.97 , pp. 264-269
    • Jing, Y.1    Wang, L.2    Xia, L.3    Chen, G.Q.4    Chen, Z.5    Miller, W.H.6    Waxman, S.7
  • 31
    • 0032933610 scopus 로고    scopus 로고
    • Malignant cells can be sensitixed to undergo growth inhibition and apoptosis by arsenic trioxide trough modulation of the glutathione redox system
    • Dai, J., Weinberg, R. S., Waxman, S., and Jing, Y. Malignant cells can be sensitixed to undergo growth inhibition and apoptosis by arsenic trioxide trough modulation of the glutathione redox system. Blood, 93: 268-277, 1999.
    • (1999) Blood , vol.93 , pp. 268-277
    • Dai, J.1    Weinberg, R.S.2    Waxman, S.3    Jing, Y.4
  • 32
    • 0034759637 scopus 로고    scopus 로고
    • The cellular metabolism and systemic toxicity of arsenic
    • Thomas, D. J., Styblo, M., and Lin, S. The cellular metabolism and systemic toxicity of arsenic. Toxicol. Appl. Pharmacol., 176: 127-44, 2001.
    • (2001) Toxicol. Appl. Pharmacol. , vol.176 , pp. 127-144
    • Thomas, D.J.1    Styblo, M.2    Lin, S.3
  • 34
    • 0037267336 scopus 로고    scopus 로고
    • Differential activation of AP-1 in human bladder epithelial cells by inorganic and methylated arsenicals
    • Drobna, Z., Jaspers, I., Thomas, D. J., and Styblo, M. Differential activation of AP-1 in human bladder epithelial cells by inorganic and methylated arsenicals. FASEB J., 17: 67-69, 2003.
    • (2003) FASEB J. , vol.17 , pp. 67-69
    • Drobna, Z.1    Jaspers, I.2    Thomas, D.J.3    Styblo, M.4
  • 35
    • 0021660653 scopus 로고
    • Selenium-glutathione peroxidase: Properties and synthesis
    • Tappel, A. L. selenium-glutathione peroxidase: properties and synthesis. Curr. Topics Cell. Regul., 24: 87-97, 1984.
    • (1984) Curr. Topics Cell. Regul. , vol.24 , pp. 87-97
    • Tappel, A.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.