Are L-adenosine and its derivatives substrates for S-adenosyl-L- homocysteine hydrolase?

Journal of Medicinal Chemistry

Volumn 48, Issue 10, 2005, Pages 3649-3653

  Wang, Mengmeng ^a   Zhang, Jinsong ^a   Andrei, Daniela ^b   Kuczera, Krzysztof ^a   Borchardt, Ronald T ^a   Wnuk, Stanislaw F ^b  

^a UNIVERSITY OF KANSAS   (United States)

^b FLORIDA INTERNATIONAL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2',3' O ISOPROPYLIDENE LEVO ADENOSINE; ADENOSINE DERIVATIVE; ADENOSYLHOMOCYSTEINASE; LEVO ADENOSINE 5' CARBOXALDEHYDE OXIME DERIVATIVE; OXIME DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DEPROTECTION REACTION; DRUG INHIBITION; ENANTIOMER; OXIDATION;

ADENOSINE; ADENOSYLHOMOCYSTEINASE; ANTI-HIV AGENTS; ANTIVIRAL AGENTS; BINDING SITES; COMPUTER SIMULATION; HEPATITIS B VIRUS; MODELS, MOLECULAR; OXIMES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 18644366017     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0490484     Document Type: Article

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