A novel mechanism-based inhibitor (6'-bromo-5',6'-didehydro-6'-deoxy- 6'-fluorohomoadenosine) that covalently modifies human placental S- adenosylhomocysteine hydrolase

Journal of Biological Chemistry

Volumn 273, Issue 29, 1998, Pages 18191-18197

  Yuan, Chong Sheng ^a,c   Wnuk, Stanislaw F ^b,d   Robins, Morris J ^b   Borchardt, Ronald T ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b Brigham Young University   (United States)

^c Tanabe Research Laboratories   (United States)

^d FLORIDA INTERNATIONAL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6' BROMO 5',6' DIDEHYDRO 6' DEOXY 6' FLUOROHOMOADENOSINE; ADENOSYLHOMOCYSTEINASE; ENZYME INHIBITOR; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; COVALENT BOND; ENZYME BINDING; ENZYME INACTIVATION; ENZYME MECHANISM; PRIORITY JOURNAL;

ADENOSYLHOMOCYSTEINASE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; DEOXYADENOSINES; ENZYME INHIBITORS; HUMANS; HYDROLASES; MODELS, CHEMICAL; PEPTIDE MAPPING; PLACENTA;

FELIS CATUS;

EID: 0032540945     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.29.18191     Document Type: Article

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