Design, synthesis, and biological evaluation of fluoroneplanocin A as the novel mechanism-based inhibitor of S-adenosylhomocysteine hydrolase

Journal of Medicinal Chemistry

Volumn 46, Issue 2, 2003, Pages 201-203

  Jeong, Lak Shin ^a   Yoo, Su Jeong ^a   Lee, Kang Man ^a   Koo, Mi Jeong ^a   Choi, Won Jun ^a   Kim, Hea Ok ^b   Moon, Hyung Ryong ^a   Lee, Min Young ^a   Park, Jae Gyu ^a   Lee, Sang Kook ^a   Chun, Moon Woo ^b  

^a Ewha Womans University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSYLHOMOCYSTEINASE INHIBITOR; ANTIVIRUS AGENT; FLUOROBENZENE; FLUORONEPLANOCIN A; N FLUOROBENZENESULFONIMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; FLUORINATION; HUMAN; HUMAN CELL; NONHUMAN;

ADENOSINE; ADENOSYLHOMOCYSTEINASE; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DRUG DESIGN; ENZYME INHIBITORS; HERPESVIRUS 1, HUMAN; HERPESVIRUS 2, HUMAN; HIV-1; HUMANS; HYDROLASES; VESICULAR STOMATITIS-INDIANA VIRUS;

EID: 0037448351     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm025557z     Document Type: Article

References (21)

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