Increased plasma HB-EGF associated with obesity and coronary artery disease

Biochemical and Biophysical Research Communications

Volumn 292, Issue 3, 2002, Pages 781-786

  Matsumoto, Satoru ^a   Kishida, Ken ^a   Shimomura, Iichiro ^a   Maeda, Norikazu ^a   Nagaretani, Hiroyuki ^a   Matsuda, Morihiro ^a   Nishizawa, Hitoshi ^a   Kihara, Shinji ^a   Funahashi, Tohru ^a   Matsuzawa, Yuji ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Adipocytokines; Atherosclerosis; Coronary artery disease; HB EGF; Obesity

Indexed keywords

HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MESSENGER RNA;

ADIPOSE TISSUE; ADULT; AGED; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR RISK; CELL MIGRATION; CELL PROLIFERATION; CORONARY ARTERY DISEASE; DISEASE ASSOCIATION; HUMAN; HUMAN TISSUE; LIPID STORAGE; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; OBESITY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SMOOTH MUSCLE FIBER;

EID: 18444415739     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2002.6720     Document Type: Article

References (36)

1. Pathophysiology and pathogenesis of visceral fat obesity
2. Visceral fat accumulation and cardiovascular disease
3. Large scale cDNA sequencing for analysis of quantitative and qualitative aspects of gene expression
4. Analysis of an expression profile of genes in the human adipose tissue
5. Role of adipocytokines on the pathogenesis of atherosclerosis in visceral obesity
6. Positional cloning of the mouse obese gene and its human homologue
7. Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin
8. Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
9. Enhanced expression of PAI-1 in visceral fat: Possible contributor to vascular disease in obesity
10. The role of TNFalpha and TNF receptors in obesity and insulin resistance
11. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (adipose most abundant gene transcript 1)
12. Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin
13. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages
14. Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway
15. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
16. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
17. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys
18. Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
19. A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF
20. Structure of heparin-binding EGF-like growth factor. Multiple forms, primary structure, and glycosylation of the mature protein
21. Heparin-binding EGF-like growth factor
22. Heparin-binding EGF-like growth factor synthesis by smooth muscle cells
23. Localization of heparin-binding EGF-like growth factor in the smooth muscle cells and macrophages of human atherosclerotic plaques
24. Localization of CD9, an enhancer protein for proheparin-binding epidermal growth factor-like growth factor, in human atherosclerotic plaques: Possible involvement of juxtacrine growth mechanism on smooth muscle cell proliferation
25. Localization of heparin-binding epidermal growth factor-like growth factor in human coronary arteries. Possible roles of HB-EGF in the formation of coronary atherosclerosis
26. Plasma heparin-binding EGF-like growth factor levels in patients after partial hepatectomy as determined with an enzyme-linked immunosorbent assay
27. Abdominal fat: Standardized technique for measurement at CT
28. Plasma leptin levels and body fat distribution
29. Role of membrane-anchored heparin-binding epidermal growth factor-like growth factor and CD9 on macrophages
30. Expression of heparin-binding epidermal growth factor-like growth factor in neointimal cells induced by balloon injury in rat carotid arteries
31. Molecular mechanism of metabolic syndrome X: Contribution of adipocytokines adipocyte-derived bioactive substances
32. Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men
33. The role of TNF alpha in adipocyte metabolism
34. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
35. Obesity and the regulation of energy balance
36. Etiology of the metabolic syndrome: Potential role of insulin resistance, leptin resistance, and other players