Localization of CD9, an enhancer protein for proheparin-binding epidermal growth factor - Like growth factor, in human atherosclerotic plaques: Possible involvement of juxtacrine growth mechanism on smooth muscle cell proliferation

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 20, Issue 5, 2000, Pages 1236-1243

  Nishida, Makoto ^a,c   Miyagawa, Jun Ichiro ^a   Yamashita, Shizuya ^a   Higashiyama, Shigeki ^b   Nakata, Atsuyuki ^a   Ouchi, Noriyuki ^a   Tamura, Ritsu ^a   Yamamori, Katsumi ^a   Kihara, Shinji ^a   Taniguchi, Naoyuki ^b   Matsuzawa, Yuji ^a  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Atherosclerosis; CD9; Heparin binding epidermal growth factor like growth factor; Vascular smooth muscle cells

Indexed keywords

CD9 ANTIGEN; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; NEUTRALIZING ANTIBODY;

ANIMAL CELL; AORTA ATHEROSCLEROSIS; ARTERY INTIMA; ARTICLE; ATHEROGENESIS; ATHEROSCLEROTIC PLAQUE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; ENHANCER REGION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; L CELL; MITOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; VASCULAR SMOOTH MUSCLE;

EID: 0034102957     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.20.5.1236     Document Type: Article

References (37)

1. Ross R. The pathogenesis of atherosclerosis. Nature. 1993;362:801-809.
2. McBride W, Lange RA, Hillis LD. Restenosis after successful coronary angioplasty: pathophysiology and prevention. N Engl J Med. 1988;318:1734-1737.
3. Higashiyama S, Abraham JA, Miller J, Fiddes JC, Klagsbrun M. A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science. 1991;251:936-939.
4. Inui Y, Higashiyama S, Kawata S, Tamura S, Miyagawa J, Taniguchi N, Matsuzawa Y. Expression of heparin-binding epidermal growth factor in human hepatocellular carcinoma. Gastroenterology. 1994; 107:1799-1804.
5. Murayama Y, Miyagawa J, Higashiyama S, Kondo S, Yabu M, Isozaki K, Kayanoki Y, Kanayama S, Shinomura Y, Taniguchi N, Matsuzawa Y. Localization of heparin-binding epidermal growth factor-like growth factor in human gastric mucosa. Gastroenterology. 1995;109: 1051-1059.
6. Marikovsky M, Breuing K, Liu PY, Eriksson E, Higashiyama S, Farber P, Abraham J, Klagsbrun M. Appearance of heparin-binding EGF-like growth factor in wound fluid as a response to injury. Proc Natl Acad Sci USA. 1993;90:3889-3893.
7. Igura T, Kawata S, Miyagawa J, Inui Y, Tamura S, Fukuda K, Isozaki K, Yamamori K, Taniguchi N, Higashiyama S, Matsuzawa Y. Expression of heparin-binding epidermal growth factor-like growth factor in neointimal cells induced by balloon injury in rat carotid arteries. Arterioscler Thromb Vasc Biol. 1996;16:1524-1531.
8. Miyagawa J, Higashiyama S, Kawata S, Inui Y, Tamura S, Yamamoto K, Nishida M, Nakamura T, Yamashita S, Matsuzawa Y, Taniguchi N. Localization of heparin-binding EGF-like growth factor in the smooth muscle cells and macrophages of human atherosclerotic plaques. J Clin Invest. 1995;95:404-411.
9. Nakata A, Miyagawa J, Yamashita S, Nishida M, Tamura R, Yamamori K, Nakamura T, Nozaki S, Takemura K, Kawata S, Taniguchi N, Higashiyama S, Matsuzawa Y. Localization of heparin-binding epidermal growth factor-like growth factor (HB-EGF) in human coronary arteries: possible roles of HB-EGF in the formation of coronary atherosclerosis. Circulation. 1996;94:2778-2786.
10. Higashiyama S, Lau K, Besner GE, Abraham JA, Klagsbrun M. Structure of heparin-binding EGF-like growth factor: multiple forms, primary structure, and glycosylation of the mature protein. J Biol Chem. 1992;267:6205-6212.
11. Dluz SM, Higashiyama S, Damm D, Abraham JA, Klagsbrun M. Heparin-binding epidermal growth factor-like growth factor expression in cultured fetal human vascular smooth muscle cells: induction of mRNA levels and secretion of active mitogen. J Biol Chem. 1993;268:18330-18334.
12. Higashiyama S, Iwamoto R, Goishi K, Raab G, Taniguchi N, Klagsbrun M, Mekada E. The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor. J Cell Biol. 1995; 128:929-938.
13. Barnard JA, Beauchamp RD, Russell WE, Dubois RN, Coffey RJ. Epidermal growth factor-related peptides and their relevance to gastrointestinal pathophysiology. Gastroenterology. 1995;108:564-580.
14. Boucheix C, Benoit P, Frachet P, Billard M, Worthington RE, Gagnon J, Uzan G. Molecular cloning of the CD9 antigen: a new family of cell surface proteins. J Biol Chem. 1991;266:117-122.
15. Kersey JH, Lebien TW, Abramson CS, Newman R, Sutherland R, Greaves M. p24: a human leukemia-associated and lymphohemopoietic progenitor cell surface structure identified with monoclonal antibody. J Exp Med. 1981;153:726-731.
16. Iwamoto R, Higashiyama S, Mitamura T, Taniguchi N, Klagsbrun M, Mekada E. Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity. EMBO J. 1994;13:2322-2330.
17. Iwamoto R, Senoh H, Okada Y, Uchida T, Mekada E. An antibody that inhibits the binding of diphtheria toxin to cells revealed the association of a 27-kDa membrane protein with the diphtheria toxin receptor. J Biol Chem. 1991;266:20463-20469.
18. Stein J, Borzillo GV, Rettenmier CW. Direct stimulation of cells expressing receptors for macrophage colony-stimulating factor (CSF-1) by a plasma membrane-bound precursor of human CSF-1. Blood. 1990;76:1308-1314.
19. Mitamura T, Higashiyama S, Taniguchi N, Klagsbrun M, Mekada E. Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity. J Biol Chem. 1995;270:1015-1019.
20. Mitamura T, Iwamoto R, Umata T, Yomo T, Urabe I, Tsuneoka M, Mekada E. The 27-kD diphtheria toxin receptor-associated protein (DRAP27) from Vero cells is the monkey homologue of human CD9 antigen: expression of DRAP27 elevates the number of diphtheria toxin receptors on toxin-sensitive cells. J Cell Biol. 1992;118: 1389-1399.
21. Jennings LK, Fox CF, Kouns WC, McKay CP, Ballou LR, Schultz HE. The activation of human platelets mediated by anti-human platelet p24/CD9 monoclonal antibodies. J Biol Chem. 1990;265: 3815-3822.
22. Masellis-Smith A, Jensen GS, Seehafer JG, Slupsky JR, Shaw AR. Anti-CD9 monoclonal antibodies induce homotypic adhesion of pre-B cell lines by a novel mechanism. J Immunol. 1990;144:1607-1613.
23. Kaprielian Z, Cho KO, Hadjiargyrou M, Patterson PH. CD9, a major platelet cell surface glycoprotein, is a ROCA antigen and is expressed in the nervous system. J Neurosci. 1995;15:562-573.
24. Scherberich A, Moog S, Haan-Archipoff G, Azorsa DO, Lanza F, Beretz A. Tetraspanin CD9 is associated with very late-acting integrins in human vascular smooth muscle cells and modulates collagen matrix reorganization. ArteriosclerThromb Vasc Biol. 1998;18:1691-1697.
25. Forsyth KD. Anti-CD9 antibodies augment neutrophil adherence to endothelium. Immunology. 1991;72:292-296.
26. Ikeyama S, Koyama M, Yamaoka M, Sasada R, Miyake M. Suppression of cell motility and metastasis by transfection with human motility-related protein (MRP-1/CD9) DNA. J Exp Med. 1993;177: 1231-1237.
27. Rubinstein E, Naour FL, Billard M, Prenant M, Boucheix C. CD9 antigen is an accessory subunit of the VLA integrin complexes. Eur J Immunol. 1994;24:3005-3013.
28. Nakamura K, Iwamoto R, Mekada E. Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites. J Cell Biol. 1995; 129-1691-1705.
29. Berditchevski F, Odintsova E. Characterization of integrin-tetraspanin adhesion complexes: role of tetraspanins in integrin signaling. J Cell Biol. 1999;146:477-492.
30. Hadjiargyrou M, Patterson PH. An anti-CD9 monoclonal antibody promotes adhesion and induces proliferation of Schwann cells in vitro. J Neurosci. 1995;15:574-583.
31. Jennings LK, Crossno JT Jr, Fox CF, White MM, Green CA. Platelet p24/CD9, a member of the tetraspanin family of proteins. Ann N Y Acad Sci. 1994;714:175-194.
32. Inui S, Higashiyama S, Hashimoto K, Higashiyama M, Yoshikawa K, Taniguchi N. Possible role of coexpression of CD9 with membrane-anchored heparin-binding EGF-like growth factor and amphiregulin in cultured human keratinocyte growth. J Cell Physiol. 1997;171: 291-298.
33. Lagaudriere-Gesbert C, Le Naour F, Lebel-Binay S, Billard M, Lemichez E, Boquet P, Boucheix C, Conjeaud H, Rubinstein E. Functional analysis of four tetraspans, CD9, CD53, CD81, and CD82, suggests a common role in costimulation, cell adhesion, and migration: only CD9 upregulates HB-EGF activity. Cell Immunol. 1997;182:105-112.
34. Takemura T, Hino S, Murata Y, Yanagida H, Okada M, Yoshioka K, Harris RC. Coexpression of CD9 augments the ability of membrane-bound heparin-binding epidermal growth factor-like growth factor (proHB-EGF) to preserve renal epithelial cell viability. Kidney Int. 1999;55:71-81.
35. Ouchi N, Kihara S, Yamashita S, Higashiyama S, Nakagawa T, Shimomura I, Funahashi T, Kameda-Takemura K, Kawata S, Taniguchi N, Matsuzawa Y. Role of membrane-anchored heparin-binding epidermal growth factor-like growth factor and CD9 on macrophages. Biochem J. 1997;328:923-928.
36. Massagué J, Pandiella A. Membrane-anchored growth factors. Annu Rev Biochem. 1993;62:515-541.
37. Tajima Y, Huang EJ, Vosseller K, Ono M, Moore MA, Besmer P. Role of dimerization of the membrane-associated growth factor kit ligand in juxtacrine signaling: the S117H mutation affects dimerization and stability-phenotypes in hematopoiesis. J Exp Med. 1998; 187:1451-1461.