A novel germline mutation of PTEN associated with brain tumours of multiple lineages

British Journal of Cancer

Volumn 86, Issue 10, 2002, Pages 1586-1591

  Staal, F J T ^a   Van der Luijt, R B ^b   Baert, M R M ^a   Drunen, J Van ^b   Bakel, H Van ^b   Peters, E ^b   De Valk, I ^b   Van Amstel, H K P ^b   Taphoorn, M J B ^b   Jansen, G H ^b   Van Veelen, C W M ^b   Burgering, B ^b   Staal, G E J ^b  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Akt; Glioma; PKB; PTEN; Transfection; Tumour suppressor gene

Indexed keywords

DNA; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ADULT; APOPTOSIS; ARTICLE; BRAIN TUMOR; CASE REPORT; CELL PROLIFERATION; COWDEN SYNDROME; ENZYME ACTIVATION; GENE MUTATION; GENETIC DISORDER; GENETIC TRANSFECTION; GLIOMA; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MENINGIOMA; MISSENSE MUTATION; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ADULT; AMINO ACID SUBSTITUTION; APOPTOSIS; BRAIN NEOPLASMS; CELL DIVISION; CELL LINEAGE; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; ENZYME ACTIVATION; FRONTAL LOBE; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HUMANS; INSULIN; LOSS OF HETEROZYGOSITY; MALE; MENINGEAL NEOPLASMS; MENINGIOMA; MODELS, MOLECULAR; MUTATION, MISSENSE; NEOPLASM PROTEINS; NEOPLASMS, MULTIPLE PRIMARY; OLIGODENDROGLIOMA; PHOSPHORIC MONOESTER HYDROLASES; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS; U937 CELLS;

EID: 18444378128     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600206     Document Type: Article

References (19)

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