TGF-β1 (transforming growth factor-β1)-mediated adhesion of gastric carcinoma cells involves a decrease in Ras/ERKs (extracellular-signal- regulated kinases) cascade activity dependent on c-Src activity

Biochemical Journal

Volumn 379, Issue 1, 2004, Pages 141-150

  Kim, Hwang Phill ^a   Lee, Mi Sook ^a   Yu, Jiyon ^b   Park, Jin Ah ^a   Jong, Hyun Soon ^a   Kim, Tae You ^a   Lee, Jung Weon ^a   Bang, Yung Jue ^a  

^a Seoul National University   (South Korea)

^b Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

c Src; Cell adhesion; Extracellular signal regulated kinases 1 and 2 (ERK1 ERK2); Gastric carcinoma; Integrin; Transforming growth factor 1 (TGF 1)

Indexed keywords

BIOMEDICAL ENGINEERING; CARCINOGENS; CELLS; DRUG PRODUCTS; GENES; GROWTH KINETICS; PROTEINS;

GENE EXPRESSION; PHOPHOLRATION;

BIOCHEMISTRY;

FIBRONECTIN; GUANOSINE TRIPHOSPHATE; INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN INHIBITOR; PROTEIN SUBUNIT; RAS PROTEIN; SCLEROPROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TYROSINE; ALPHA3 INTEGRIN; ENZYME INHIBITOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; TGFB1 PROTEIN, HUMAN; TGFB1 PROTEIN, RAT; TRANSFORMING GROWTH FACTOR BETA; TUMOR PROTEIN;

ARTICLE; BASAL CELL; CANCER CELL CULTURE; CELL ADHESION; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL PROCESSING; UPREGULATION; ANIMAL; BIOSYNTHESIS; CARCINOMA; CULTURE MEDIUM; DNA METHYLATION; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; STOMACH TUMOR;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CARCINOMA; CELL ADHESION; CULTURE MEDIA, SERUM-FREE; DNA METHYLATION; ENZYME INHIBITORS; EXTRACELLULAR MATRIX; FIBRONECTINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GUANOSINE TRIPHOSPHATE; HUMANS; INTEGRIN ALPHA3; INTEGRINS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM PROTEINS; PROTEIN SUBUNITS; RAS GTPASE-ACTIVATING PROTEINS; RATS; SRC-FAMILY KINASES; STOMACH NEOPLASMS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 1842866205     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031408     Document Type: Article

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