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Volumn 5, Issue 1, 2004, Pages 3-13

Aldosterone and cardiovascular remodelling: Focus on myocardial failure

Author keywords

Aldosterone; Heart failure; Myocardial; Remodelling; Vascular

Indexed keywords

ALDOSTERONE; ALDOSTERONE ANTAGONIST; ALDOSTERONE SYNTHASE; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANTIOXIDANT; CALCINEURIN INHIBITOR; CANDESARTAN; CANRENONE; CORTICOSTEROID; CYCLOHEXIMIDE; CYCLOSPORIN A; DACTINOMYCIN; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; EPLERENONE; GLUCOCORTICOID ANTAGONIST; LOSARTAN; MIFEPRISTONE; MINERALOCORTICOID RECEPTOR; NEUROHORMONE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PYRROLIDINE DITHIOCARBAMATE; SPIRONOLACTONE; TACROLIMUS; UNINDEXED DRUG; VALSARTAN;

EID: 1842737277     PISSN: 14703203     EISSN: None     Source Type: Journal    
DOI: 10.3317/jraas.2004.005     Document Type: Review
Times cited : (13)

References (149)
  • 2
    • 0029550256 scopus 로고
    • Aldosterone escape during ACE inhibitor therapy in chronic heart failure
    • Struthers AD. Aldosterone escape during ACE inhibitor therapy in chronic heart failure. Eur Heart J 1995;16(suppl N):103-06.
    • (1995) Eur. Heart J. , vol.16 , Issue.SUPPL. N , pp. 103-106
    • Struthers, A.D.1
  • 3
    • 0025088737 scopus 로고
    • Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality
    • CONSENSUS Trial Study Group
    • Swedberg K, Eneroth P, Kjekshus J, Wilhelmsen L. Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group. Circulation 1990;82:1730-6.
    • (1990) Circulation , vol.82 , pp. 1730-1736
    • Swedberg, K.1    Eneroth, P.2    Kjekshus, J.3    Wilhelmsen, L.4
  • 4
    • 0024842845 scopus 로고
    • Characterization of two genes encoding human steroid 11 beta-hydroxylase (P-450(11) beta)
    • Mornet E, Dupont J, Vitek A, White PC. Characterization of two genes encoding human steroid 11 beta-hydroxylase (P-450(11) beta). J Biol Chem 1989;264:20961-7.
    • (1989) J. Biol. Chem. , vol.264 , pp. 20961-20967
    • Mornet, E.1    Dupont, J.2    Vitek, A.3    White, P.C.4
  • 5
    • 0035830440 scopus 로고    scopus 로고
    • Aldosterone production is activated in failing ventricle in humans
    • Mizuno Y, Yoshimura M, Yasue H et al. Aldosterone production is activated in failing ventricle in humans. Circulation 2001;103:72-7.
    • (2001) Circulation , vol.103 , pp. 72-77
    • Mizuno, Y.1    Yoshimura, M.2    Yasue, H.3
  • 6
    • 0033852821 scopus 로고    scopus 로고
    • Spironolactone inhibits the transcardiac extraction of aldosterone in patients with congestive heart failure
    • TsutamotoT, Wada A, Maeda K et al. Spironolactone inhibits the transcardiac extraction of aldosterone in patients with congestive heart failure. J Am Coll Cardiol 2000;36:838-44.
    • (2000) J. Am. Coll. Cardiol. , vol.36 , pp. 838-844
    • Tsutamoto, T.1    Wada, A.2    Maeda, K.3
  • 8
    • 0032570807 scopus 로고    scopus 로고
    • Myocardial production of aldosterone and corticosterone in the rat. Physiological regulation
    • Silvestre JS, Robert V, Heymes C et al. Myocardial production of aldosterone and corticosterone in the rat. Physiological regulation. J Biol Chem 1998;273:4883-91.
    • (1998) J. Biol. Chem. , vol.273 , pp. 4883-4891
    • Silvestre, J.S.1    Robert, V.2    Heymes, C.3
  • 11
    • 0036209144 scopus 로고    scopus 로고
    • Aldosterone synthase (CYP11B2) expression and myocardial fibrosis in the failing human heart
    • Satoh M, Nakamura M, Saitoh H et al. Aldosterone synthase (CYP11B2) expression and myocardial fibrosis in the failing human heart. Clin Sci (Lond) 2002;102:381-6.
    • (2002) Clin. Sci. (Lond) , vol.102 , pp. 381-386
    • Satoh, M.1    Nakamura, M.2    Saitoh, H.3
  • 12
    • 18544389493 scopus 로고    scopus 로고
    • Expression of aldosterone synthase gene in failing human heart: Quantitative analysis using modified real-time polymerase chain reaction
    • Yoshimura M, Nakamura S, Ito T et al. Expression of aldosterone synthase gene in failing human heart: quantitative analysis using modified real-time polymerase chain reaction. J Clin Endocrinol Metab 2002;87:3936-40.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 3936-3940
    • Yoshimura, M.1    Nakamura, S.2    Ito, T.3
  • 13
    • 0036013909 scopus 로고    scopus 로고
    • Effects of long-term enalapril and losartan therapy of heart failure on cardiovascular aldosterone
    • Xiu JC, Wu P, Xu JP et al. Effects of long-term enalapril and losartan therapy of heart failure on cardiovascular aldosterone. J Endocrinol Invest 2002;25:463-8.
    • (2002) J. Endocrinol. Invest. , vol.25 , pp. 463-468
    • Xiu, J.C.1    Wu, P.2    Xu, J.P.3
  • 14
    • 0036911628 scopus 로고    scopus 로고
    • Time course of gene expression in rat experimental autoimmune myocarditis
    • Hanawa H, Abe S, Hayashi M et al. Time course of gene expression in rat experimental autoimmune myocarditis. Clin Sci (Lond) 2002;103:623-32.
    • (2002) Clin. Sci. (Lond) , vol.103 , pp. 623-632
    • Hanawa, H.1    Abe, S.2    Hayashi, M.3
  • 16
    • 0032570807 scopus 로고    scopus 로고
    • Myocardial production of aldosterone and corticosterone in the rat. Physiological regulation
    • Silvestre JS, Robert V, Heymes C et al. Myocardial production of aldosterone and corticosterone in the rat. Physiological regulation. J Biol Chem 1998;273:4883-91.
    • (1998) J. Biol. Chem. , vol.273 , pp. 4883-4891
    • Silvestre, J.S.1    Robert, V.2    Heymes, C.3
  • 17
    • 0037373553 scopus 로고    scopus 로고
    • Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: Effects of 11 beta-hydroxysteroid dehydrogenase inactivation
    • Young MJ, Moussa L, Dilley R, Funder JW. Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: effects of 11 beta-hydroxysteroid dehydrogenase inactivation. Endocrinology 2003;144:1121-5.
    • (2003) Endocrinology , vol.144 , pp. 1121-1125
    • Young, M.J.1    Moussa, L.2    Dilley, R.3    Funder, J.W.4
  • 18
    • 0029788193 scopus 로고    scopus 로고
    • Regulation of aldosterone synthase in human vascular endothelial cells by angiotensin II and adrenocorticotropin
    • Takeda Y, Miyamori I, YonedaT et al. Regulation of aldosterone synthase in human vascular endothelial cells by angiotensin II and adrenocorticotropin. J Clin Endocrinol Metab 1996;81:2797-800.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 2797-2800
    • Takeda, Y.1    Miyamori, I.2    Yoneda, T.3
  • 19
    • 0038343383 scopus 로고    scopus 로고
    • Aldosterone: Direct effects on and production by the heart
    • White PC. Aldosterone: direct effects on and production by the heart. J Clin Endocrinol Metab 2003;88:2376-83.
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 2376-2383
    • White, P.C.1
  • 20
    • 0026689952 scopus 로고
    • Immunohistochemical and biochemical evidence for a cardiovascular mineralocorticoid receptor
    • Lombes M, Oblin ME, Gasc JM, Baulieu EE, Farman N, Bonvalet JP. Immunohistochemical and biochemical evidence for a cardiovascular mineralocorticoid receptor. Circ Res 1992; 71:503-10.
    • (1992) Circ. Res. , vol.71 , pp. 503-510
    • Lombes, M.1    Oblin, M.E.2    Gasc, J.M.3    Baulieu, E.E.4    Farman, N.5    Bonvalet, J.P.6
  • 21
    • 0029022285 scopus 로고
    • Prerequisite for cardiac aldosterone action. Mineralocorticoid receptor and 11 beta-hydroxysteroid dehydrogenase in the human heart
    • Lombes M, Alfaidy N, Eugene E, Lessana A, Farman N, Bonvalet JP. Prerequisite for cardiac aldosterone action. Mineralocorticoid receptor and 11 beta-hydroxysteroid dehydrogenase in the human heart. Circulation 1995;92:175-82.
    • (1995) Circulation , vol.92 , pp. 175-182
    • Lombes, M.1    Alfaidy, N.2    Eugene, E.3    Lessana, A.4    Farman, N.5    Bonvalet, J.P.6
  • 22
    • 0031949446 scopus 로고    scopus 로고
    • Regulation of sodium transport by steroid hormones
    • Bonvalet JP. Regulation of sodium transport by steroid hormones. Kidney Int 1998;65(suppl):S49-S56.
    • (1998) Kidney Int. , vol.65 , Issue.SUPPL.
    • Bonvalet, J.P.1
  • 23
    • 0012473279 scopus 로고
    • The nuclear receptor superfamily: The second decade
    • Mangelsdorf DJ, Thummel C, Beato M et al. The nuclear receptor superfamily: the second decade. Cell 1995;83:835-9.
    • (1995) Cell , vol.83 , pp. 835-839
    • Mangelsdorf, D.J.1    Thummel, C.2    Beato, M.3
  • 24
    • 0031046241 scopus 로고    scopus 로고
    • 11 beta-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess
    • White PC, Mune T, Agarwal AK. 11 beta-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess. Endocr Rev 1997;18:135-56.
    • (1997) Endocr. Rev. , vol.18 , pp. 135-156
    • White, P.C.1    Mune, T.2    Agarwal, A.K.3
  • 25
    • 0027182566 scopus 로고
    • Glucocorticoid metabolism in the cardiac interstitium: 11 beta-hydroxysteroid dehydrogenase activity in cardiac fibroblasts
    • Slight S, Ganjam VK, Nonneman DJ, Weber KT. Glucocorticoid metabolism in the cardiac interstitium: 11 beta-hydroxysteroid dehydrogenase activity in cardiac fibroblasts. J Lab Clin Med 1993;122:180-7.
    • (1993) J. Lab. Clin. Med. , vol.122 , pp. 180-187
    • Slight, S.1    Ganjam, V.K.2    Nonneman, D.J.3    Weber, K.T.4
  • 26
    • 0029931451 scopus 로고    scopus 로고
    • Does aldosterone-induced cardiac fibrosis involve direct effects on cardiac fibroblasts?
    • Kohler E, Bertschin S, Woodtli T, Resink T, Erne P. Does aldosterone-induced cardiac fibrosis involve direct effects on cardiac fibroblasts? J Vasc Res 1996;33:315-26.
    • (1996) J. Vasc. Res. , vol.33 , pp. 315-326
    • Kohler, E.1    Bertschin, S.2    Woodtli, T.3    Resink, T.4    Erne, P.5
  • 27
    • 0037230196 scopus 로고    scopus 로고
    • Aldosterone stimulates proliferation of cardiac fibroblasts by activating Ki-RasA and MAPK 1/2 signaling
    • Stockand JD, Meszaros JG. Aldosterone stimulates proliferation of cardiac fibroblasts by activating Ki-RasA and MAPK 1/2 signaling. Am J Physiol Heart Circ Physiol 2003;284:H176-H184.
    • (2003) Am. J. Physiol. Heart Circ. Physiol. , vol.284
    • Stockand, J.D.1    Meszaros, J.G.2
  • 28
    • 0035090207 scopus 로고    scopus 로고
    • Mineralocorticoid receptor affects AP-1 and nuclear factor-kappab activation in angiotensin II-induced cardiac injury
    • Fiebeler A, Schmidt F, Muller DN et al. Mineralocorticoid receptor affects AP-1 and nuclear factor-kappab activation in angiotensin II-induced cardiac injury. Hypertension 2001;37(2 Part 2):787-93.
    • (2001) Hypertension , vol.37 , Issue.2 PART 2 , pp. 787-793
    • Fiebeler, A.1    Schmidt, F.2    Muller, D.N.3
  • 29
    • 0037195911 scopus 로고    scopus 로고
    • Human epidermal growth factor receptor-1 expression renders Chinese hamster ovary cells sensitive to alternative aldosterone signaling
    • Krug AW, Schuster C, Gassner B et al. Human epidermal growth factor receptor-1 expression renders Chinese hamster ovary cells sensitive to alternative aldosterone signaling. J Biol Chem 2002;277:45892-7.
    • (2002) J. Biol. Chem. , vol.277 , pp. 45892-45897
    • Krug, A.W.1    Schuster, C.2    Gassner, B.3
  • 30
    • 0242384919 scopus 로고    scopus 로고
    • Aldosterone stimulates epidermal growth factor receptor (EGFR) expression
    • Krug AW, Grossmann C, Schuster C et al. Aldosterone stimulates epidermal growth factor receptor (EGFR) expression. J Biol Chem 2003;278:43060-6.
    • (2003) J. Biol. Chem. , vol.278 , pp. 43060-43066
    • Krug, A.W.1    Grossmann, C.2    Schuster, C.3
  • 31
    • 0037488488 scopus 로고    scopus 로고
    • Transgenic model of aldosterone-driven cardiac hypertrophy and heart failure
    • Qin W, Rudolph AE, Bond BR et al. Transgenic model of aldosterone-driven cardiac hypertrophy and heart failure. Circ Res 2003;93:69-76.
    • (2003) Circ. Res. , vol.93 , pp. 69-76
    • Qin, W.1    Rudolph, A.E.2    Bond, B.R.3
  • 32
    • 0036108564 scopus 로고    scopus 로고
    • Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase
    • Hafezi-Moghadam A, Simoncini T, Yang E et al. Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase. Nat Med 2002;8:473-9.
    • (2002) Nat. Med. , vol.8 , pp. 473-479
    • Hafezi-Moghadam, A.1    Simoncini, T.2    Yang, E.3
  • 33
    • 0037076296 scopus 로고    scopus 로고
    • Reversible cardiac fibrosis and heart failure induced by conditional expression of an antisense mRNA of the mineralocorticoid receptor in cardiomyocytes
    • Beggah AT, Escoubet B, Puttini S et al. Reversible cardiac fibrosis and heart failure induced by conditional expression of an antisense mRNA of the mineralocorticoid receptor in cardiomyocytes. Proc Natl Acad Sci USA 2002;99:7160-5.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 7160-7165
    • Beggah, A.T.1    Escoubet, B.2    Puttini, S.3
  • 34
    • 0029166430 scopus 로고
    • Rapid aldosterone signaling in vascular smooth muscle cells: Involvement of phospholipase C, diacylglycerol and protein kinase C alpha
    • Christ M, Meyer C, Sippel K, Wehling M. Rapid aldosterone signaling in vascular smooth muscle cells: involvement of phospholipase C, diacylglycerol and protein kinase C alpha. Biochem Biophys Res Commun 1995;213:123-9.
    • (1995) Biochem. Biophys. Res. Commun. , vol.213 , pp. 123-129
    • Christ, M.1    Meyer, C.2    Sippel, K.3    Wehling, M.4
  • 35
    • 0030737574 scopus 로고    scopus 로고
    • Aldosterone rapidly represses protein kinase C activity in neonatal rat cardiomyocytes in vitro
    • Sato A, Liu JP, Funder JW. Aldosterone rapidly represses protein kinase C activity in neonatal rat cardiomyocytes in vitro. Endocrinology 1997;138:3410-16.
    • (1997) Endocrinology , vol.138 , pp. 3410-3416
    • Sato, A.1    Liu, J.P.2    Funder, J.W.3
  • 36
    • 0142020893 scopus 로고    scopus 로고
    • Aldosterone potentiates 1,25-dihydroxyvitamin D3 action in renal thick ascending limb via a nongenomic, ERK-dependent pathway
    • Good DW, George T, Watts BA 3rd. Aldosterone potentiates 1,25-dihydroxyvitamin D3 action in renal thick ascending limb via a nongenomic, ERK-dependent pathway. Am J Physiol Cell Physiol 2003;285:C1122-30.
    • (2003) Am. J. Physiol. Cell Physiol. , vol.285
    • Good, D.W.1    George, T.2    Watts III, B.A.3
  • 37
  • 38
    • 0031790731 scopus 로고    scopus 로고
    • Oxidative stress and the pathogenesis of heart failure
    • Ball AM, Sole MJ. Oxidative stress and the pathogenesis of heart failure. Cardiol Clin 1998;16(4):665-6ix.
    • (1998) Cardiol. Clin. , vol.16 , Issue.4
    • Ball, A.M.1    Sole, M.J.2
  • 39
    • 0035140261 scopus 로고    scopus 로고
    • A controlled clinical trial of vitamin E supplementation in patients with congestive heart failure
    • Keith ME, Jeejeebhoy KN, Langer A et al. A controlled clinical trial of vitamin E supplementation in patients with congestive heart failure. Am J Clin Nutr 2001;73:219-24.
    • (2001) Am. J. Clin. Nutr. , vol.73 , pp. 219-224
    • Keith, M.E.1    Jeejeebhoy, K.N.2    Langer, A.3
  • 40
    • 0033634980 scopus 로고    scopus 로고
    • Conditioned nutritional requirements and the pathogenesis and treatment of myocardial failure
    • Sole MJ, Jeejeebhoy KN. Conditioned nutritional requirements and the pathogenesis and treatment of myocardial failure. Curr Opin Clin Nutr Metab Care 2000;3:417-24.
    • (2000) Curr. Opin. Clin. Nutr. Metab. Care , vol.3 , pp. 417-424
    • Sole, M.J.1    Jeejeebhoy, K.N.2
  • 42
    • 0035800882 scopus 로고    scopus 로고
    • Oxidative stressmediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy
    • Cesselli D, Jakoniuk I, Barlucchi L et al. Oxidative stressmediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy. Circ Res 2001;89:279-86.
    • (2001) Circ. Res. , vol.89 , pp. 279-286
    • Cesselli, D.1    Jakoniuk, I.2    Barlucchi, L.3
  • 43
    • 0035838457 scopus 로고    scopus 로고
    • Enhanced generation of reactive oxygen species in the limb skeletal muscles from a murine infarct model of heart failure
    • Tsutsui H, IdeT, Hayashidani S et al. Enhanced generation of reactive oxygen species in the limb skeletal muscles from a murine infarct model of heart failure. Circulation 2001;104: 134-6.
    • (2001) Circulation , vol.104 , pp. 134-136
    • Tsutsui, H.1    Ide, T.2    Hayashidani, S.3
  • 44
    • 0033922326 scopus 로고    scopus 로고
    • Angiotensin II induces renal oxidant stress in vivo and heme oxygenase-1 in vivo and in vitro
    • Haugen EN, Croatt AJ, Nath KA. Angiotensin II induces renal oxidant stress in vivo and heme oxygenase-1 in vivo and in vitro. Kidney Int 2000;58:144-52.
    • (2000) Kidney Int. , vol.58 , pp. 144-152
    • Haugen, E.N.1    Croatt, A.J.2    Nath, K.A.3
  • 45
    • 0030005713 scopus 로고    scopus 로고
    • Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone
    • Rajagopalan S, Kurz S, Munzel T et al. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. J Clin Invest 1996;97:1916-23.
    • (1996) J. Clin. Invest. , vol.97 , pp. 1916-1923
    • Rajagopalan, S.1    Kurz, S.2    Munzel, T.3
  • 46
    • 0012906173 scopus 로고    scopus 로고
    • Superoxide anion from the adventitia of the rat thoracic aorta inactivates nitric oxide
    • Wang HD, Pagano PJ, Du Y et al. Superoxide anion from the adventitia of the rat thoracic aorta inactivates nitric oxide. Circ Res 1998;82:810-18.
    • (1998) Circ. Res. , vol.82 , pp. 810-818
    • Wang, H.D.1    Pagano, P.J.2    Du, Y.3
  • 49
    • 0033021938 scopus 로고    scopus 로고
    • Superoxide anion production is increased in a model of genetic hypertension: Role of the endothelium
    • Kerr S, Brosnan MJ, McIntyre M, Reid JL, Dominiczak AF, Hamilton CA. Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium. Hypertension 1999;33:1353-8.
    • (1999) Hypertension , vol.33 , pp. 1353-1358
    • Kerr, S.1    Brosnan, M.J.2    McIntyre, M.3    Reid, J.L.4    Dominiczak, A.F.5    Hamilton, C.A.6
  • 50
    • 0033588198 scopus 로고    scopus 로고
    • Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium
    • Ide T, Tsutsui H, Kinugawa S et al. Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium. Circ Res 1999;85:357-63.
    • (1999) Circ. Res. , vol.85 , pp. 357-363
    • Ide, T.1    Tsutsui, H.2    Kinugawa, S.3
  • 51
    • 0034735910 scopus 로고    scopus 로고
    • Metallothioneins, oxidative stress and the cardiovascular system
    • Nath R, Kumar D, Li T, Singal PK. Metallothioneins, oxidative stress and the cardiovascular system. Toxicology 2000; 155:17-26.
    • (2000) Toxicology , vol.155 , pp. 17-26
    • Nath, R.1    Kumar, D.2    Li, T.3    Singal, P.K.4
  • 52
    • 0034636125 scopus 로고    scopus 로고
    • Vascular superoxide production and vasomotor function in hypertension induced by deoxycorticosterone acetate-salt
    • Somers MJ, Mavromatis K, Galis ZS, Harrison DG. Vascular superoxide production and vasomotor function in hypertension induced by deoxycorticosterone acetate-salt. Circulation 2000;101:1722-8.
    • (2000) Circulation , vol.101 , pp. 1722-1728
    • Somers, M.J.1    Mavromatis, K.2    Galis, Z.S.3    Harrison, D.G.4
  • 53
    • 0022640297 scopus 로고
    • Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
    • Gryglewski RJ, Palmer RM, Moncada S. Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 1986;320:454-6.
    • (1986) Nature , vol.320 , pp. 454-456
    • Gryglewski, R.J.1    Palmer, R.M.2    Moncada, S.3
  • 54
    • 0032956654 scopus 로고    scopus 로고
    • Two-week administration of tempol attenuates both hypertension and renal excretion of 8-Iso prostaglandin f2alpha
    • Schnackenberg CG, Wilcox CS. Two-week administration of tempol attenuates both hypertension and renal excretion of 8-Iso prostaglandin f2alpha. Hypertension 1999;33(1 Pt 2):424-8.
    • (1999) Hypertension , vol.33 , Issue.1 PART 2 , pp. 424-428
    • Schnackenberg, C.G.1    Wilcox, C.S.2
  • 55
    • 0020668901 scopus 로고
    • Potential oxidative pathways of catecholamines in the formation of lipid peroxides and genesis of heart disease
    • Singal PK, Beamish RE, Dhalla NS. Potential oxidative pathways of catecholamines in the formation of lipid peroxides and genesis of heart disease. Adv Exp Med Biol 1983;161:391-401.
    • (1983) Adv. Exp. Med. Biol. , vol.161 , pp. 391-401
    • Singal, P.K.1    Beamish, R.E.2    Dhalla, N.S.3
  • 56
    • 0033781454 scopus 로고    scopus 로고
    • Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology
    • Griendling KK, Sorescu D, Lassegue B, Ushio-Fukai M. Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler Thromb Vasc Biol 2000;20: 2175-83.
    • (2000) Arterioscler. Thromb. Vasc. Biol. , vol.20 , pp. 2175-2183
    • Griendling, K.K.1    Sorescu, D.2    Lassegue, B.3    Ushio-Fukai, M.4
  • 58
    • 0038141826 scopus 로고    scopus 로고
    • Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling
    • Pu Q, Neves MF, Virdis A, Touyz RM, Schiffrin EL. Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling. Hypertension 2003;42:49-55.
    • (2003) Hypertension , vol.42 , pp. 49-55
    • Pu, Q.1    Neves, M.F.2    Virdis, A.3    Touyz, R.M.4    Schiffrin, E.L.5
  • 59
    • 0036841807 scopus 로고    scopus 로고
    • Aldosterone-induced inflammation in the rat heart: Role of oxidative stress
    • Sun Y, Zhang J, Lu L, Chen SS, Quinn MT, Weber KT. Aldosterone-induced inflammation in the rat heart: role of oxidative stress. Am J Pathol 2002;161:1773-81.
    • (2002) Am. J. Pathol. , vol.161 , pp. 1773-1781
    • Sun, Y.1    Zhang, J.2    Lu, L.3    Chen, S.S.4    Quinn, M.T.5    Weber, K.T.6
  • 60
    • 0027959070 scopus 로고
    • Effect of a nonselective endothelin antagonist on vascular remodeling in deoxycorticosterone acetate-salt hypertensive rats. Evidence for a role of endothelin in vascular hypertrophy
    • Li JS, Lariviere R, Schiffrin EL. Effect of a nonselective endothelin antagonist on vascular remodeling in deoxycorticosterone acetate-salt hypertensive rats. Evidence for a role of endothelin in vascular hypertrophy. Hypertension 1994; 24:183-8.
    • (1994) Hypertension , vol.24 , pp. 183-188
    • Li, J.S.1    Lariviere, R.2    Schiffrin, E.L.3
  • 61
    • 0036672213 scopus 로고    scopus 로고
    • Contribution of endothelin-1 to renal activator protein-1 activation and macrophage infiltration in aldosterone-induced hypertension
    • Tostes RC, Touyz RM, He G, Chen X, Schiffrin EL. Contribution of endothelin-1 to renal activator protein-1 activation and macrophage infiltration in aldosterone-induced hypertension. Clin Sci (Lond) 2002;103(suppl 48):25S-30S.
    • (2002) Clin. Sci. (Lond) , vol.103 , Issue.SUPPL. 48
    • Tostes, R.C.1    Touyz, R.M.2    He, G.3    Chen, X.4    Schiffrin, E.L.5
  • 62
    • 0035926310 scopus 로고    scopus 로고
    • Gene expression of endothelin-1 (ET-1) and release of mature peptide by activated human neutrophils
    • Cambiaggi C, Mencarelli M, Muscettola M, Grasso G. Gene expression of endothelin-1 (ET-1) and release of mature peptide by activated human neutrophils. Cytokine 2001; 14:230-3.
    • (2001) Cytokine , vol.14 , pp. 230-233
    • Cambiaggi, C.1    Mencarelli, M.2    Muscettola, M.3    Grasso, G.4
  • 64
    • 0033178254 scopus 로고    scopus 로고
    • Interactions between endothelin-1 and the renin-angiotensin-aldosterone system
    • Rossi GP, Sacchetto A, Cesari M, Pessina AC. Interactions between endothelin-1 and the renin-angiotensin-aldosterone system. Cardiovasc Res 1999;43:300-07.
    • (1999) Cardiovasc. Res. , vol.43 , pp. 300-307
    • Rossi, G.P.1    Sacchetto, A.2    Cesari, M.3    Pessina, A.C.4
  • 65
    • 0037780685 scopus 로고    scopus 로고
    • Effect of eplerenone, a selective aldosterone blocker, on blood pressure, serum and macrophage oxidative stress, and atherosclerosis in apolipoprotein E-deficient mice
    • Keidar S, Hayek T, Kaplan M et al. Effect of eplerenone, a selective aldosterone blocker, on blood pressure, serum and macrophage oxidative stress, and atherosclerosis in apolipoprotein E-deficient mice. J Cardiovasc Pharmacol 2003;41:955-63.
    • (2003) J. Cardiovasc. Pharmacol. , vol.41 , pp. 955-963
    • Keidar, S.1    Hayek, T.2    Kaplan, M.3
  • 66
    • 0034651798 scopus 로고    scopus 로고
    • Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure
    • Farquharson CA, Struthers AD. Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure. Circulation 2000;101:594-7.
    • (2000) Circulation , vol.101 , pp. 594-597
    • Farquharson, C.A.1    Struthers, A.D.2
  • 68
    • 0342460492 scopus 로고    scopus 로고
    • Hormonal changes and catabolic/anabolic imbalance in chronic heart failure and their importance for cardiac cachexia
    • Anker SD, Chua TP, Ponikowski P et al. Hormonal changes and catabolic/anabolic imbalance in chronic heart failure and their importance for cardiac cachexia. Circulation 1997;96: 526-34.
    • (1997) Circulation , vol.96 , pp. 526-534
    • Anker, S.D.1    Chua, T.P.2    Ponikowski, P.3
  • 69
    • 0035818917 scopus 로고    scopus 로고
    • Aldosterone in congestive heart failure
    • Weber KT. Aldosterone in congestive heart failure. N Engl J Med 2001;345:1689-97.
    • (2001) N. Engl. J. Med. , vol.345 , pp. 1689-1697
    • Weber, K.T.1
  • 70
    • 85019316271 scopus 로고
    • Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
    • The CONSENSUS Trial Study Group
    • Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). The CONSENSUS Trial Study Group. N Engl J Med 1987;316:1429-35.
    • (1987) N. Engl. J. Med. , vol.316 , pp. 1429-1435
  • 71
    • 0025913812 scopus 로고
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. The SOLVD Investigators
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. The SOLVD Investigators. N Engl J Med 1991;325:293-302.
    • (1991) N. Engl. J. Med. , vol.325 , pp. 293-302
  • 72
    • 0033028679 scopus 로고    scopus 로고
    • How often are angiotensin II and aldosterone concentrations raised during chronic ACE inhibitor treatment in cardiac failure?
    • MacFadyen RJ, Lee AF, Morton JJ, Pringle SD, Struthers AD. How often are angiotensin II and aldosterone concentrations raised during chronic ACE inhibitor treatment in cardiac failure? Heart 1999;82:57-61.
    • (1999) Heart , vol.82 , pp. 57-61
    • MacFadyen, R.J.1    Lee, A.F.2    Morton, J.J.3    Pringle, S.D.4    Struthers, A.D.5
  • 73
    • 0033533456 scopus 로고    scopus 로고
    • Comparison of candesartan, enalapril, and their combination in congestive heart failure: Randomized evaluation of strategies for left ventricular dysfunction (RESOLVD) pilot study. The RESOLVD Pilot Study Investigators
    • McKelvie RS, Yusuf S, Pericak D et al. Comparison of candesartan, enalapril, and their combination in congestive heart failure: randomized evaluation of strategies for left ventricular dysfunction (RESOLVD) pilot study. The RESOLVD Pilot Study Investigators. Circulation 1999;100:1056-64.
    • (1999) Circulation , vol.100 , pp. 1056-1064
    • McKelvie, R.S.1    Yusuf, S.2    Pericak, D.3
  • 74
    • 0019865836 scopus 로고
    • Rise in plasma concentration of aldosterone during long-term angiotensin II suppression
    • Staessen J, Lijnen P, Fagard R, Verschueren LJ, Amery A. Rise in plasma concentration of aldosterone during long-term angiotensin II suppression. J Endocrinol 1981;91:457-65.
    • (1981) J. Endocrinol. , vol.91 , pp. 457-465
    • Staessen, J.1    Lijnen, P.2    Fagard, R.3    Verschueren, L.J.4    Amery, A.5
  • 75
    • 0035818884 scopus 로고    scopus 로고
    • A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure
    • Cohn JN,Tognoni G. A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N Engl J Med 2001;345:1667-75.
    • (2001) N. Engl. J. Med. , vol.345 , pp. 1667-1675
    • Cohn, J.N.1    Tognoni, G.2
  • 76
    • 0041408235 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: The CHARM-Added trial
    • McMurray JJ, Ostergren J, Swedberg K et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial. Lancet 2003;362: 767-71.
    • (2003) Lancet , vol.362 , pp. 767-771
    • McMurray, J.J.1    Ostergren, J.2    Swedberg, K.3
  • 77
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
    • Pitt B, Zannad F, Remme WJ et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 1999;341:709-17.
    • (1999) N. Engl. J. Med. , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3
  • 78
    • 0027227646 scopus 로고
    • Anti-aldosterone treatment and the prevention of myocardial fibrosis in primary and secondary hyperaldosteronism
    • Brilla CG, Matsubara LS, Weber KT. Anti-aldosterone treatment and the prevention of myocardial fibrosis in primary and secondary hyperaldosteronism. J Mol Cell Cardiol 1993;25: 563-75.
    • (1993) J. Mol. Cell Cardiol. , vol.25 , pp. 563-575
    • Brilla, C.G.1    Matsubara, L.S.2    Weber, K.T.3
  • 79
    • 0025675680 scopus 로고
    • Remodeling of the rat right and left ventricles in experimental hypertension
    • Brilla CG, Pick R, Tan LB, Janicki JS, Weber KT. Remodeling of the rat right and left ventricles in experimental hypertension. Circ Res 1990;67:1355-64.
    • (1990) Circ. Res. , vol.67 , pp. 1355-1364
    • Brilla, C.G.1    Pick, R.2    Tan, L.B.3    Janicki, J.S.4    Weber, K.T.5
  • 80
    • 0026638123 scopus 로고
    • Reactive and reparative myocardial fibrosis in arterial hypertension in the rat
    • Brilla CG, Weber KT. Reactive and reparative myocardial fibrosis in arterial hypertension in the rat. Cardiovasc Res 1992;26:671-7.
    • (1992) Cardiovasc. Res. , vol.26 , pp. 671-677
    • Brilla, C.G.1    Weber, K.T.2
  • 81
    • 0037180412 scopus 로고    scopus 로고
    • Increased carotid wall elastic modulus and fibronectin in aldosterone-salt-treated rats: Effects of eplerenone
    • Lacolley P, Labat C, Pujol A, Delcayre C, Benetos A, Safar M. Increased carotid wall elastic modulus and fibronectin in aldosterone-salt-treated rats: effects of eplerenone. Circulation 2002;106:2848-53.
    • (2002) Circulation , vol.106 , pp. 2848-2853
    • Lacolley, P.1    Labat, C.2    Pujol, A.3    Delcayre, C.4    Benetos, A.5    Safar, M.6
  • 82
    • 0038410160 scopus 로고    scopus 로고
    • Aldosterone inhibits inducible nitric oxide synthase in neonatal rat cardiomyocytes
    • Chun TY, Bloem LJ, Pratt JH. Aldosterone inhibits inducible nitric oxide synthase in neonatal rat cardiomyocytes. Endocrinology 2003;144:1712-17.
    • (2003) Endocrinology , vol.144 , pp. 1712-1717
    • Chun, T.Y.1    Bloem, L.J.2    Pratt, J.H.3
  • 83
    • 0033840926 scopus 로고    scopus 로고
    • Induction of cardiac fibrosis by aldosterone
    • Lijnen P, Petrov V. Induction of cardiac fibrosis by aldosterone. J Mol Cell Cardiol 2000;32:865-79.
    • (2000) J. Mol. Cell Cardiol. , vol.32 , pp. 865-879
    • Lijnen, P.1    Petrov, V.2
  • 84
    • 85047676796 scopus 로고
    • Aldosterone and cardiac fibrosis: In vitro studies
    • Fullerton MJ, Funder JW. Aldosterone and cardiac fibrosis: in vitro studies. Cardiovasc Res 1994;28:1863-7.
    • (1994) Cardiovasc. Res. , vol.28 , pp. 1863-1867
    • Fullerton, M.J.1    Funder, J.W.2
  • 85
    • 0030222294 scopus 로고    scopus 로고
    • Potentiation of angiotensin II action by corticosteroids in vascular tissue
    • Ullian ME, Walsh LG, Morinelli TA. Potentiation of angiotensin II action by corticosteroids in vascular tissue. Cardiovasc Res 1996;32:266-73.
    • (1996) Cardiovasc. Res. , vol.32 , pp. 266-273
    • Ullian, M.E.1    Walsh, L.G.2    Morinelli, T.A.3
  • 86
    • 0028275578 scopus 로고
    • Collagen metabolism in cultured adult rat cardiac fibroblasts: Response to angiotensin II and aldosterone
    • Brilla CG, Zhou G, Matsubara L, Weber KT. Collagen metabolism in cultured adult rat cardiac fibroblasts: response to angiotensin II and aldosterone. J Mol Cell Cardiol 1994;26: 809-20.
    • (1994) J. Mol. Cell Cardiol. , vol.26 , pp. 809-820
    • Brilla, C.G.1    Zhou, G.2    Matsubara, L.3    Weber, K.T.4
  • 87
    • 0024146930 scopus 로고
    • Cell-associated plasminogen activation: Regulation and physiological functions
    • Saksela O, Rifkin DB. Cell-associated plasminogen activation: regulation and physiological functions. Annu Rev Cell Biol 1988;4:93-126.
    • (1988) Annu. Rev. Cell Biol. , vol.4 , pp. 93-126
    • Saksela, O.1    Rifkin, D.B.2
  • 88
    • 0024840912 scopus 로고
    • Proteinases and extracellular matrix remodeling
    • Alexander CM, Werb Z. Proteinases and extracellular matrix remodeling. Curr Opin Cell Biol 1989;1:974-82.
    • (1989) Curr. Opin. Cell Biol. , vol.1 , pp. 974-982
    • Alexander, C.M.1    Werb, Z.2
  • 89
    • 0030054203 scopus 로고    scopus 로고
    • Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene
    • Eitzman DT, McCoy RD, Zheng X et al. Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene. J Clin Invest 1996;97:232-7.
    • (1996) J. Clin. Invest. , vol.97 , pp. 232-237
    • Eitzman, D.T.1    McCoy, R.D.2    Zheng, X.3
  • 90
    • 0026688810 scopus 로고
    • Aldosterone enhances angiotensin II receptor binding and inositol phosphate responses
    • Ullian ME, Schelling JR, Linas SL. Aldosterone enhances angiotensin II receptor binding and inositol phosphate responses. Hypertension 1992;20:67-73.
    • (1992) Hypertension , vol.20 , pp. 67-73
    • Ullian, M.E.1    Schelling, J.R.2    Linas, S.L.3
  • 91
    • 0034457808 scopus 로고    scopus 로고
    • Synergistic effect of adrenal steroids and angiotensin II on plasminogen activator inhibitor-1 production
    • Brown NJ, Kim KS, Chen YQ et al. Synergistic effect of adrenal steroids and angiotensin II on plasminogen activator inhibitor-1 production. J Clin Endocrinol Metab 2000;85:336-44.
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 336-344
    • Brown, N.J.1    Kim, K.S.2    Chen, Y.Q.3
  • 93
    • 0036893647 scopus 로고    scopus 로고
    • Selective aldosterone blockade prevents angiotensin II/salt-induced vascular inflammation in the rat heart
    • Rocha R, Martin-Berger CL, Yang P, Scherrer R, Delyani J, McMahon E. Selective aldosterone blockade prevents angiotensin II/salt-induced vascular inflammation in the rat heart. Endocrinology 2002;143:4828-36.
    • (2002) Endocrinology , vol.143 , pp. 4828-4836
    • Rocha, R.1    Martin-Berger, C.L.2    Yang, P.3    Scherrer, R.4    Delyani, J.5    McMahon, E.6
  • 94
    • 0032588244 scopus 로고    scopus 로고
    • Angiotensin AT1 receptor subtype as a cardiac target of aldosterone: Role in aldosterone-salt-induced fibrosis
    • Robert V, Heymes C, Silvestre JS, Sabri A, Swynghedauw B, Delcayre C. Angiotensin AT1 receptor subtype as a cardiac target of aldosterone: role in aldosterone-salt-induced fibrosis. Hypertension 1999;33:981-6.
    • (1999) Hypertension , vol.33 , pp. 981-986
    • Robert, V.1    Heymes, C.2    Silvestre, J.S.3    Sabri, A.4    Swynghedauw, B.5    Delcayre, C.6
  • 95
    • 0343081008 scopus 로고    scopus 로고
    • Aldosterone upregulates Ca(2+) current in adult rat cardiomyocytes
    • Benitah JP, Vassort G. Aldosterone upregulates Ca(2+) current in adult rat cardiomyocytes. Circ Res 1999;85:1139-45.
    • (1999) Circ. Res. , vol.85 , pp. 1139-1145
    • Benitah, J.P.1    Vassort, G.2
  • 96
    • 0032540267 scopus 로고    scopus 로고
    • A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
    • Molkentin JD, Lu JR, Antos CL et al. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 1998;93:215-28.
    • (1998) Cell , vol.93 , pp. 215-228
    • Molkentin, J.D.1    Lu, J.R.2    Antos, C.L.3
  • 97
    • 0037065888 scopus 로고    scopus 로고
    • Calcineurin inhibition attenuates mineralocorticoid-induced cardiac hypertrophy
    • Takeda Y, Yoneda T, Demura M, Usukura M, Mabuchi H. Calcineurin inhibition attenuates mineralocorticoid-induced cardiac hypertrophy. Circulation 2002;105:677-9.
    • (2002) Circulation , vol.105 , pp. 677-679
    • Takeda, Y.1    Yoneda, T.2    Demura, M.3    Usukura, M.4    Mabuchi, H.5
  • 98
    • 0034038579 scopus 로고    scopus 로고
    • Aldosterone mediates angiotensin II-stimulated rat vascular smooth muscle cell proliferation
    • Xiao F, Puddefoot JR, Vinson GP. Aldosterone mediates angiotensin II-stimulated rat vascular smooth muscle cell proliferation. J Endocrinol 2000;165:533-6.
    • (2000) J. Endocrinol. , vol.165 , pp. 533-536
    • Xiao, F.1    Puddefoot, J.R.2    Vinson, G.P.3
  • 99
    • 0036193852 scopus 로고    scopus 로고
    • Aldosterone and D-glucose stimulate the proliferation of human cardiac myofibroblasts in vitro
    • Neumann S, Huse K, Semrau R et al. Aldosterone and D-glucose stimulate the proliferation of human cardiac myofibroblasts in vitro. Hypertension 2002;39:756-60.
    • (2002) Hypertension , vol.39 , pp. 756-760
    • Neumann, S.1    Huse, K.2    Semrau, R.3
  • 100
    • 0034455339 scopus 로고    scopus 로고
    • Sodium-induced cardiac aldosterone synthesis causes cardiac hypertrophy
    • Takeda Y, Yoneda T, Demura M, Miyamori I, Mabuchi H. Sodium-induced cardiac aldosterone synthesis causes cardiac hypertrophy. Endocrinology 2000;141:1901-04.
    • (2000) Endocrinology , vol.141 , pp. 1901-1904
    • Takeda, Y.1    Yoneda, T.2    Demura, M.3    Miyamori, I.4    Mabuchi, H.5
  • 102
    • 85047694494 scopus 로고    scopus 로고
    • A mechanistic role for cardiac myocyte apoptosis in heart failure
    • Wencker D, Chandra M, Nguyen K et al. A mechanistic role for cardiac myocyte apoptosis in heart failure. J Clin Invest 2003;111:1497-504.
    • (2003) J. Clin. Invest. , vol.111 , pp. 1497-1504
    • Wencker, D.1    Chandra, M.2    Nguyen, K.3
  • 103
    • 0001739436 scopus 로고    scopus 로고
    • Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell
    • Leri A, Claudio PP, Li Q et al. Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. J Clin Invest 1998; 101:1326-42.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1326-1342
    • Leri, A.1    Claudio, P.P.2    Li, Q.3
  • 104
    • 0036901481 scopus 로고    scopus 로고
    • Appraisal of the role of angiotensin II and aldosterone in ventricular myocyte apoptosis in adult normotensive rat
    • De Angelis N, Fiordaliso F, Latini R et al. Appraisal of the role of angiotensin II and aldosterone in ventricular myocyte apoptosis in adult normotensive rat. J Mol Cell Cardiol 2002; 34:1655-65.
    • (2002) J. Mol. Cell Cardiol. , vol.34 , pp. 1655-1665
    • De Angelis, N.1    Fiordaliso, F.2    Latini, R.3
  • 106
    • 0037185555 scopus 로고    scopus 로고
    • Mifepristone protects CA1 hippocampal neurons following traumatic brain injury in rat
    • McCullers DL, Sullivan PG, Scheff SW, Herman JP. Mifepristone protects CA1 hippocampal neurons following traumatic brain injury in rat. Neuroscience 2002;109:219-30.
    • (2002) Neuroscience , vol.109 , pp. 219-230
    • McCullers, D.L.1    Sullivan, P.G.2    Scheff, S.W.3    Herman, J.P.4
  • 107
    • 1642534461 scopus 로고    scopus 로고
    • Mice lacking osteopontin exhibit increased left ventricular dilation and reduced fibrosis after aldosterone infusion
    • Sam F, Kerstetter DL, Ooi H et al. Mice lacking osteopontin exhibit increased left ventricular dilation and reduced fibrosis after aldosterone infusion. Am J Hypertens 2004; 17:188-93.
    • (2004) Am. J. Hypertens. , vol.17 , pp. 188-193
    • Sam, F.1    Kerstetter, D.L.2    Ooi, H.3
  • 108
    • 0034658131 scopus 로고    scopus 로고
    • Effect of spironolactone on ventricular arrhythmias in congestive heart failure secondary to idiopathic dilated or to ischemic cardiomyopathy
    • Ramires FJ, Mansur A, Coelho O et al. Effect of spironolactone on ventricular arrhythmias in congestive heart failure secondary to idiopathic dilated or to ischemic cardiomyopathy. Am J Cardiol 2000;85:1207-11.
    • (2000) Am. J. Cardiol. , vol.85 , pp. 1207-1211
    • Ramires, F.J.1    Mansur, A.2    Coelho, O.3
  • 109
    • 0028906168 scopus 로고
    • Relations between heart failure, ejection fraction, arrhythmia suppression and mortality: Analysis of the Cardiac Arrhythmia Suppression Trial
    • Hallstrom A, Pratt CM, Greene HL et al. Relations between heart failure, ejection fraction, arrhythmia suppression and mortality: analysis of the Cardiac Arrhythmia Suppression Trial. J Am Coll Cardiol 1995;25:1250-7.
    • (1995) J. Am. Coll. Cardiol. , vol.25 , pp. 1250-1257
    • Hallstrom, A.1    Pratt, C.M.2    Greene, H.L.3
  • 110
    • 0027465156 scopus 로고
    • Angiotensin-converting enzyme inhibitor and spironolactone combination therapy. New objectives in congestive heart failure treatment
    • Zannad F. Angiotensin-converting enzyme inhibitor and spironolactone combination therapy. New objectives in congestive heart failure treatment. Am J Cardiol 1993;71:34A-39A.
    • (1993) Am. J. Cardiol. , vol.71
    • Zannad, F.1
  • 111
    • 0028860490 scopus 로고
    • Effects of adding spironolactone to an angiotensin-converting enzyme inhibitor in chronic congestive heart failure secondary to coronary artery disease
    • Barr CS, Lang CC, Hanson J, Arnott M, Kennedy N, Struthers AD. Effects of adding spironolactone to an angiotensin-converting enzyme inhibitor in chronic congestive heart failure secondary to coronary artery disease. Am J Cardiol 1995;76:1259-65.
    • (1995) Am. J. Cardiol. , vol.76 , pp. 1259-1265
    • Barr, C.S.1    Lang, C.C.2    Hanson, J.3    Arnott, M.4    Kennedy, N.5    Struthers, A.D.6
  • 112
    • 0019967321 scopus 로고
    • Catecholamine-mediated constrictor effects of aldosterone on vascular smooth muscle
    • Weber MA, Purdy RE. Catecholamine-mediated constrictor effects of aldosterone on vascular smooth muscle. Life Sci 1982;30:2009-17.
    • (1982) Life Sci. , vol.30 , pp. 2009-2017
    • Weber, M.A.1    Purdy, R.E.2
  • 113
    • 0034727695 scopus 로고    scopus 로고
    • Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: Insights from the randomized aldactone evaluation study (RALES). Rales Investigators
    • Zannad F, Alla F, Dousset B, Perez A, Pitt B. Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: insights from the randomized aldactone evaluation study (RALES). Rales Investigators. Circulation 2000;102:2700-06.
    • (2000) Circulation , vol.102 , pp. 2700-2706
    • Zannad, F.1    Alla, F.2    Dousset, B.3    Perez, A.4    Pitt, B.5
  • 114
    • 0142085752 scopus 로고    scopus 로고
    • Effects of eplerenone, enalapril, and eplerenone/enalapril in patients with essential hypertension and left ventricular hypertrophy: The 4E-left ventricular hypertrophy study
    • Pitt B, Reichek N, Willenbrock R et al. Effects of eplerenone, enalapril, and eplerenone/enalapril in patients with essential hypertension and left ventricular hypertrophy: the 4E-left ventricular hypertrophy study. Circulation 2003; 108:1831-8.
    • (2003) Circulation , vol.108 , pp. 1831-1838
    • Pitt, B.1    Reichek, N.2    Willenbrock, R.3
  • 115
    • 0035948631 scopus 로고    scopus 로고
    • Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals
    • Gerstein HC, Mann JF, Yi Q et al. Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals. JAMA 2001;286:421-6.
    • (2001) JAMA , vol.286 , pp. 421-426
    • Gerstein, H.C.1    Mann, J.F.2    Yi, Q.3
  • 116
    • 0001644827 scopus 로고    scopus 로고
    • Eplerenone Reduces Proteinuria in Type II Diabetes Mellitus: Implications for Aldosterone Involvement in the Pathogenesis of Renal Dysfunction
    • Epstein M, Buckalew V, Altamirano J, Roniker B, Krause S, Kleiman J. Eplerenone Reduces Proteinuria in Type II Diabetes Mellitus: Implications for Aldosterone Involvement in the Pathogenesis of Renal Dysfunction. JACC 2002;39(suppl 1): 249A.
    • (2002) JACC , vol.39 , Issue.SUPPL. 1
    • Epstein, M.1    Buckalew, V.2    Altamirano, J.3    Roniker, B.4    Krause, S.5    Kleiman, J.6
  • 117
    • 0037417252 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
    • Pitt B, Remme W, Zannad F, Neaton J et al. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med 2003;348:1309-21.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 1309-1321
    • Pitt, B.1    Remme, W.2    Zannad, F.3    Neaton, J.4
  • 118
    • 0032974550 scopus 로고    scopus 로고
    • Eplerenone: Antihypertensive treatment of heart failure: Aldosterone antagonist
    • Rabasseda X, Silvestre J, Castaner J. Eplerenone: antihypertensive treatment of heart failure: aldosterone antagonist. Drugs Future 1999;24:488-501.
    • (1999) Drugs Future , vol.24 , pp. 488-501
    • Rabasseda, X.1    Silvestre, J.2    Castaner, J.3
  • 119
    • 0037900716 scopus 로고    scopus 로고
    • Aldosterone resurgens-letter from EPHESUS
    • Funder JW. Aldosterone resurgens-letter from EPHESUS. J Clin Endocrinol Metab 2003;88:2373-5.
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 2373-2375
    • Funder, J.W.1
  • 120
    • 0029928474 scopus 로고    scopus 로고
    • Salt sensitivity of blood pressure in humans
    • Weinberger MH. Salt sensitivity of blood pressure in humans. Hypertension 1996;27(3 Pt 2):481-90.
    • (1996) Hypertension , vol.27 , Issue.3 PART 2 , pp. 481-490
    • Weinberger, M.H.1
  • 121
    • 0032878222 scopus 로고    scopus 로고
    • Levels of mineralocorticoids in whites and blacks
    • Pratt JH, Rebhun JF, Zhou L et al. Levels of mineralocorticoids in whites and blacks. Hypertension 1999;34:315-19.
    • (1999) Hypertension , vol.34 , pp. 315-319
    • Pratt, J.H.1    Rebhun, J.F.2    Zhou, L.3
  • 122
    • 0035348104 scopus 로고    scopus 로고
    • Heart failure in blacks: Etiologic and epidemiologic differences
    • Yancy CW. Heart failure in blacks: etiologic and epidemiologic differences. Curr Cardiol Rep 2001;3:191-7.
    • (2001) Curr. Cardiol. Rep. , vol.3 , pp. 191-197
    • Yancy, C.W.1
  • 123
    • 0037414091 scopus 로고    scopus 로고
    • Efficacy and tolerability of eplerenone and losartan in hypertensive black and white patients
    • Flack JM, Oparil S, Pratt JH et al. Efficacy and tolerability of eplerenone and losartan in hypertensive black and white patients. J Am Coll Cardiol 2003;41:1148-55.
    • (2003) J. Am. Coll. Cardiol. , vol.41 , pp. 1148-1155
    • Flack, J.M.1    Oparil, S.2    Pratt, J.H.3
  • 124
    • 0035997359 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in mild-to-moderate hypertension
    • Weinberger MH, Roniker B, Krause SL, Weiss RJ. Eplerenone, a selective aldosterone blocker, in mild-to-moderate hypertension. Am J Hypertens 2002;15:709-16.
    • (2002) Am. J. Hypertens. , vol.15 , pp. 709-716
    • Weinberger, M.H.1    Roniker, B.2    Krause, S.L.3    Weiss, R.J.4
  • 125
    • 0036330671 scopus 로고    scopus 로고
    • Efficacy of eplerenone added to renin-angiotensin blockade in hypertensive patients
    • Krum H, Nolly H, Workman D et al. Efficacy of eplerenone added to renin-angiotensin blockade in hypertensive patients. Hypertension 2002;40:117-23.
    • (2002) Hypertension , vol.40 , pp. 117-123
    • Krum, H.1    Nolly, H.2    Workman, D.3
  • 126
    • 0029788193 scopus 로고    scopus 로고
    • Regulation of aldosterone synthase in human vascular endothelial cells by angiotensin II and adrenocorticotropin
    • Takeda Y, Miyamori I, Yoneda T et al. Regulation of aldosterone synthase in human vascular endothelial cells by angiotensin II and adrenocorticotropin. J Clin Endocrinol Metab 1996;81:2797-800.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 2797-2800
    • Takeda, Y.1    Miyamori, I.2    Yoneda, T.3
  • 127
    • 0027997406 scopus 로고
    • Vascular aldosterone. Biosynthesis and a link to angiotensin II-induced hypertrophy of vascular smooth muscle cells
    • Hatakeyama H, Miyamori I, Fujita T, Takeda Y, Takeda R, Yamamoto H. Vascular aldosterone. Biosynthesis and a link to angiotensin II-induced hypertrophy of vascular smooth muscle cells. J Biol Chem 1994;269:24316-20.
    • (1994) J. Biol. Chem. , vol.269 , pp. 24316-24320
    • Hatakeyama, H.1    Miyamori, I.2    Fujita, T.3    Takeda, Y.4    Takeda, R.5    Yamamoto, H.6
  • 129
    • 0028831049 scopus 로고
    • Production of aldosterone in isolated rat blood vessels
    • Takeda Y, Miyamori I, Yoneda T et al. Production of aldosterone in isolated rat blood vessels. Hypertension 1995;25:170-3.
    • (1995) Hypertension , vol.25 , pp. 170-173
    • Takeda, Y.1    Miyamori, I.2    Yoneda, T.3
  • 130
    • 0024329644 scopus 로고
    • Molecular cloning of a mineralocorticoid (type I) receptor complementary DNA from rat hippocampus
    • Patel PD, Sherman TG, Goldman DJ, Watson SJ. Molecular cloning of a mineralocorticoid (type I) receptor complementary DNA from rat hippocampus. Mol Endocrinol 1989;3:1877-85.
    • (1989) Mol. Endocrinol. , vol.3 , pp. 1877-1885
    • Patel, P.D.1    Sherman, T.G.2    Goldman, D.J.3    Watson, S.J.4
  • 131
    • 0023585013 scopus 로고
    • High affinity aldosterone binding sites (type I receptors) in rat heart
    • Pearce P, Funder JW. High affinity aldosterone binding sites (type I receptors) in rat heart. Clin Exp Pharmacol Physiol 1987;14(11-12):859-66.
    • (1987) Clin. Exp. Pharmacol. Physiol. , vol.14 , Issue.11-12 , pp. 859-866
    • Pearce, P.1    Funder, J.W.2
  • 132
    • 0031041163 scopus 로고    scopus 로고
    • Vascular aldosterone in genetically hypertensive rats
    • Takeda Y, Miyamori I, Inaba S et al. Vascular aldosterone in genetically hypertensive rats. Hypertension 1997;29(1 Pt 1): 45-8.
    • (1997) Hypertension , vol.29 , Issue.1 PART 1 , pp. 45-48
    • Takeda, Y.1    Miyamori, I.2    Inaba, S.3
  • 133
    • 0030925069 scopus 로고    scopus 로고
    • Prevention of aortic fibrosis by spironolactone in spontaneously hypertensive rats
    • Benetos A, Lacolley P, Safar ME. Prevention of aortic fibrosis by spironolactone in spontaneously hypertensive rats. Arterioscler Thromb Vasc Biol 1997;17:1152-6.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 1152-1156
    • Benetos, A.1    Lacolley, P.2    Safar, M.E.3
  • 134
    • 0028785677 scopus 로고
    • Determinants of cardiac fibrosis in experimental hypermineralocorticoid states
    • Young M, Head G, Funder J. Determinants of cardiac fibrosis in experimental hypermineralocorticoid states. Am J Physiol 1995;269(4 Pt 1):E657-E662.
    • (1995) Am. J. Physiol. , vol.269 , Issue.4 PART 1
    • Young, M.1    Head, G.2    Funder, J.3
  • 135
    • 0028982073 scopus 로고
    • Aldosterone inhibits nitric oxide synthesis in rat vascular smooth muscle cells induced by interleukin-1 beta
    • Ikeda U, Kanbe T, Nakayama I, Kawahara Y, Yokoyama M, Shimada K. Aldosterone inhibits nitric oxide synthesis in rat vascular smooth muscle cells induced by interleukin-1 beta. Eur J Pharmacol 1995;290:69-73.
    • (1995) Eur. J. Pharmacol. , vol.290 , pp. 69-73
    • Ikeda, U.1    Kanbe, T.2    Nakayama, I.3    Kawahara, Y.4    Yokoyama, M.5    Shimada, K.6
  • 136
    • 0036796624 scopus 로고    scopus 로고
    • Aldosterone induces acute endothelial dysfunction in vivo in humans: Evidence for an aldosterone-induced vasculopathy
    • Farquharson CA, Struthers AD. Aldosterone induces acute endothelial dysfunction in vivo in humans: evidence for an aldosterone-induced vasculopathy. Clin Sci (Lond) 2002;103: 425-31.
    • (2002) Clin. Sci. (Lond) , vol.103 , pp. 425-431
    • Farquharson, C.A.1    Struthers, A.D.2
  • 137
    • 0032169994 scopus 로고    scopus 로고
    • Inverse relationship between aldosterone and large artery compliance in chronically treated heart failure patients
    • Duprez DA, De Buyzere ML, Rietzschel ER et al. Inverse relationship between aldosterone and large artery compliance in chronically treated heart failure patients. Eur Heart J 1998;19:1371-6.
    • (1998) Eur. Heart J. , vol.19 , pp. 1371-1376
    • Duprez, D.A.1    De Buyzere, M.L.2    Rietzschel, E.R.3
  • 138
    • 0031406824 scopus 로고    scopus 로고
    • Association between increased plasma levels of aldosterone and decreased systemic arterial compliance in subjects with essential hypertension
    • Blacher J, Amah G, Girerd X et al. Association between increased plasma levels of aldosterone and decreased systemic arterial compliance in subjects with essential hypertension. Am J Hypertens 1997;10(12 Pt 1):1326-34.
    • (1997) Am. J. Hypertens. , vol.10 , Issue.12 PART 1 , pp. 1326-1334
    • Blacher, J.1    Amah, G.2    Girerd, X.3
  • 139
    • 0029020640 scopus 로고
    • Haplotype analysis of CYP11B2
    • White PC, Slutsker L. Haplotype analysis of CYP11B2. Endocr Res 1995;21:437-442.
    • (1995) Endocr. Res. , vol.21 , pp. 437-442
    • White, P.C.1    Slutsker, L.2
  • 140
    • 0031911098 scopus 로고    scopus 로고
    • Associations between human aldosterone synthase (CYP11B2) gene polymorphisms and left ventricular size, mass, and function
    • Kupari M, Hautanen A, Lankinen L et al. Associations between human aldosterone synthase (CYP11B2) gene polymorphisms and left ventricular size, mass, and function. Circulation 1998;97:569-75.
    • (1998) Circulation , vol.97 , pp. 569-575
    • Kupari, M.1    Hautanen, A.2    Lankinen, L.3
  • 141
    • 0031846630 scopus 로고    scopus 로고
    • Structural analysis and evaluation of the aldosterone synthase gene in hypertension
    • Brand E, Chatelain N, Mulatero P et al. Structural analysis and evaluation of the aldosterone synthase gene in hypertension. Hypertension 1998;32:198-204.
    • (1998) Hypertension , vol.32 , pp. 198-204
    • Brand, E.1    Chatelain, N.2    Mulatero, P.3
  • 142
    • 0035120417 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor-153A/G and 1166A/C gene polymorphisms and increase in aortic stiffness with age in hypertensive subjects
    • Lajemi M, Labat C, Gautier S et al. Angiotensin II type 1 receptor-153A/G and 1166A/C gene polymorphisms and increase in aortic stiffness with age in hypertensive subjects. J Hypertens 2001;19:407-13.
    • (2001) J. Hypertens. , vol.19 , pp. 407-413
    • Lajemi, M.1    Labat, C.2    Gautier, S.3
  • 143
    • 0036899784 scopus 로고    scopus 로고
    • Association between aldosterone synthase (CYP11B2) gene polymorphisin and left ventricular volume in patients with dilated cardiomyopathy
    • Takai E, Akita H, Kanazawa K et al. Association between aldosterone synthase (CYP11B2) gene polymorphisin and left ventricular volume in patients with dilated cardiomyopathy. Heart 2002;88:649-50.
    • (2002) Heart , vol.88 , pp. 649-650
    • Takai, E.1    Akita, H.2    Kanazawa, K.3
  • 144
    • 0036268068 scopus 로고    scopus 로고
    • An aldosterone synthase gene variant is associated with improvement in left ventricular ejection fraction in dilated cardiomyopathy
    • Tiago AD, Badenhorst D, Skudicky D et al. An aldosterone synthase gene variant is associated with improvement in left ventricular ejection fraction in dilated cardiomyopathy. Cardiovasc Res 2002;54:584-9.
    • (2002) Cardiovasc. Res. , vol.54 , pp. 584-589
    • Tiago, A.D.1    Badenhorst, D.2    Skudicky, D.3
  • 145
    • 0029762716 scopus 로고    scopus 로고
    • High glucose stimulates aldosterone-induced hypertrophy via type I mineralocorticoid receptors in neonatal rat cardiomyocytes
    • Sato A, Funder JW. High glucose stimulates aldosterone-induced hypertrophy via type I mineralocorticoid receptors in neonatal rat cardiomyocytes. Endocrinology 1996;137:4145-53.
    • (1996) Endocrinology , vol.137 , pp. 4145-4153
    • Sato, A.1    Funder, J.W.2
  • 146
    • 0035947750 scopus 로고    scopus 로고
    • Exaggerated left ventricular dilation and reduced collagen deposition after myocardial infarction in mice lacking osteopontin
    • Trueblood NA, Xie Z, Communal C et al. Exaggerated left ventricular dilation and reduced collagen deposition after myocardial infarction in mice lacking osteopontin. Circ Res 2001;88:1080-7.
    • (2001) Circ. Res. , vol.88 , pp. 1080-1087
    • Trueblood, N.A.1    Xie, Z.2    Communal, C.3
  • 147
    • 0037428123 scopus 로고    scopus 로고
    • DNA microarray profiling to identify angiotensin-responsive genes in vascular smooth muscle cells: Potential mediators of vascular disease
    • Campos AH, Zhao Y, Pollman MJ, Gibbons GH. DNA microarray profiling to identify angiotensin-responsive genes in vascular smooth muscle cells: potential mediators of vascular disease. Circ Res 2003;92:111-18.
    • (2003) Circ. Res. , vol.92 , pp. 111-118
    • Campos, A.H.1    Zhao, Y.2    Pollman, M.J.3    Gibbons, G.H.4
  • 148
    • 0038299329 scopus 로고    scopus 로고
    • Aldosteronism: An immunostimulatory state precedes proinflammatory/fibrogenic cardiac phenotype
    • Gerling IC, Sun Y, Ahokas RA et al. Aldosteronism: an immunostimulatory state precedes proinflammatory/fibrogenic cardiac phenotype. Am J Physiol Heart Circ Physiol 2003;285:H813-H821.
    • (2003) Am. J. Physiol. Heart Circ. Physiol. , vol.285
    • Gerling, I.C.1    Sun, Y.2    Ahokas, R.A.3
  • 149
    • 0642306163 scopus 로고    scopus 로고
    • Aldosteronism and Peripheral Blood Mononuclear Cell Activation. A Neuroendocrine-Immune Interface
    • Ahokas RA, Warrington KJ, Gerling IC et al. Aldosteronism and Peripheral Blood Mononuclear Cell Activation. A Neuroendocrine-Immune Interface. Circ Res 2003;93:124-35.
    • (2003) Circ. Res. , vol.93 , pp. 124-135
    • Ahokas, R.A.1    Warrington, K.J.2    Gerling, I.C.3


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