S-(2-Chloroethyl)glutathione-generated p53 Mutation Spectra Are Influenced by Differential Repair Rates More than Sites of Initial DNA Damage

Journal of Biological Chemistry

Volumn 279, Issue 14, 2004, Pages 13435-13446

  Valadez, J Gerardo ^a,b   Guengerich, F Peter ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ETHYLENE; UREA; YEAST;

DNA REPAIR; NUCLEOTIDES; PHENOTYPES;

MUTAGENESIS;

1,2 DIBROMOETHANE; DNA; ETHYLNITROSOUREA; GLUTATHIONE; GLUTATHIONE DERIVATIVE; MUSTARD GAS DERIVATIVE; NUCLEOTIDE; PROTEIN P53; S (2 CHLOROETHYL)GLUTATHIONE; UNCLASSIFIED DRUG;

ARTICLE; DNA DAMAGE; DNA MODIFICATION; DNA REPAIR; EXON; FLUORESCENCE; GENE MUTATION; HALF LIFE TIME; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REPORTER GENE;

ALKYLATING AGENTS; DNA ADDUCTS; DNA REPAIR; GENES, REPORTER; GLUTATHIONE; MUTAGENESIS; MUTAGENS; NUCLEOTIDES; SACCHAROMYCES CEREVISIAE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 1842691080     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M312358200     Document Type: Article

References (84)

1. Bauer, K. H. (1928) Mutationstheorie der Geschwulstenstehung, Springer Verlag, Berlin
2. Heidelberger, C. (1975) Annu. Rev. Biochem. 44, 79-121
3. Ames, B. N. (1979) Science 204, 587-593
4. Benzer, S. (1961) Proc. Natl. Acad. Sci. U. S. A. 47, 403-416
5. Rogozin, I. B., and Pavlov, Y. I. (2003) Mutat. Res. 544, 65-85
6. Olson, W. A., Habermann, R. T., Weisburger, E. K., Ward, J. M., and Weisburger, J. H. (1973) J. Natl. Cancer Inst. 51, 1993-1995
7. Rannug, U. (1980) Mutat. Res. 76, 269-295
8. Sun, M. (1984) Science 223, 464-466
9. Foster, P. L., Wilkinson, W. G., Miller, J. K., Sullivan, A. D., and Barnes, W. M. (1988) Mutat. Res. 194, 171-181
10. Ballering, L. A. P., Nivard, M. J. M., and Vogel, E. W. (1994) Carcinogenesis 15, 869-875
11. Graves, R. J., Trueman, P., Jones, S., and Green, T. (1996) Mutagenesis 11, 229-233
12. Cmarik, J. L., Humphreys, W. G., Bruner, K. L., Lloyd, R. S., Tibbetts, C., and Guengerich, F. P. (1992) J. Biol. Chem. 267, 6672-6679
13. Ozawa, N., and Guengerich, F. P. (1983) Proc. Natl. Acad. Sci. U. S. A. 80, 5266-5270
14. Peterson, L. A., Harris, T. M., and Guengerich, F. P. (1988) J. Am. Chem. Soc. 110, 3284-3291
15. Humphreys, W. G., Kim, D.-H., Cmarik, J. L., Shimada, T., and Guengerich, F. P. (1990) Biochemistry 29, 10342-10350
16. Liu, L., Pegg, A. E., Williams, K. M., and Guengerich, F. P. (2002) J. Biol. Chem. 277, 37920-37928
17. Koga, N., Inskeep, P. B., Harris, T. M., and Guengerich, F. P. (1986) Biochemistry 25, 2192-2198
18. Inskeep, P. B., Koga, N., Cmarik, J. L., and Guengerich, F. P. (1986) Cancer Res. 46, 2839-2844
19. Kim, D.-H., Humphreys, W. G., and Guengerich, F. P. (1990) Chem. Res. Toxicol. 3, 587-594
20. Horsfall, M. J., Gordon, A. J. E., Burns, P. A., Zielenska, M., van der Vliet, G. M. E., and Glickman, B. W. (1990) Environ. Mol. Mutagen. 15, 107-122
21. Zarbl, H., Sukumar, S., Arthur, A. V., Martin-Zanca, D., and Barbacid, M. (1985) Nature 315, 382-385
22. Wei, S. J. C., Chang, R. L., Wong, C. Q., Bhachech, N., Cui, X. X., Hennig, E., Yagi, H., Sayer, J. M., Jerina, D. M., Preston, B. D., and Conney, A. H. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 11227-11230
23. Pfeifer, G. P. (2000) Mutat. Res. 450, 1-3
24. Pfeifer, G. P. (2000) Mutat. Res. 450, 155-166
25. Hu, W., Feng, Z., and Tang, M. S. (2003) Biochemistry 42, 10012-10023
26. Pfeifer, G. P., Drouin, R., Riggs, A. D., and Holmquist, G. P. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 1374-1378
27. Tornaletti, S., and Pfeifer, G. P. (1994) Science 263, 1436-1438
28. Yoon, J. H., Lee, C. S., O'Connor, T. R., Yasui, A., and Pfeifer, G. P. (2000) J. Mol. Biol. 299, 681-693
29. Denissenko, M. F., Pao, A., Tang, M., and Pfeifer, G. P. (1996) Science 274, 430-432
30. Smith, L. E., Denissenko, M. F., Bennett, W. P., Li, H., Amin, S., Tang, M., and Pfeifer, G. P. (2000) J. Natl. Cancer Inst. 92, 803-811
31. Yoon, J. H., Smith, L. E., Feng, Z., Tang, M., Lee, C. S., and Pfeifer, G. P. (2001) Cancer Res. 61, 7110-7117
32. Scharer, E., and Iggo, R. (1992) Nucleic Acids Res. 20, 1539-1545
33. Ishioka, C., Frebourg, T., Yan, Y. X., Vidal, M., Friend, S. H., Schmidt, S., and Iggo, R. (1993)Nat. Genet. 5, 124-129
34. Flaman, J. M., Frebourg, T., Moreau, V., Charbonnier, F., Martin, C., Chappuis, P., Sappino, A. P., Limacher, I. M., Bron, L., Benhattar, J., Tada, M., van Meir, E. G., Estreicher, A., and Iggo, R. D. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 3963-3967
35. Moshinsky, D. J., and Wogan, G. N. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 2266-2271
36. Moshinsky, D. J., and Wogan, G. N. (2000) Environ. Mol. Mutagen. 35, 31-38
37. Fronza, G., Inga, A., Monti, P., Scott, G., Campomenosi, P., Menichini, P., Ottaggio, L., Viaggi, S., Burns, P. A., Gold, B., and Abbondandolo, A. (2000) Mutat. Res. 462, 293-301
38. Lee, G. S., Blonsky, K. S., Van On, D. L., Savage, E. A., Morgan, A. R., and von Borstel, R. C. (1992) J. Mol. Biol. 223, 617-626
39. Maxam, A. M., and Gilbert, W. (1977) Proc. Natl. Acad. Sci. U. S. A. 74, 560-564
40. Maxam, A. M., and Gilbert, W. (1980) Methods Enzymol. 65, 499-560
41. Kohn, K. W., Hartley, J. A., and Mattes, W. B. (1987) Nucleic Acids Res. 15, 10531-10549
42. Mueller, P. R., and Wold, B. (1989) Science 246, 780-786
43. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K. (1995) Current Protocols in Molecular Biology, John Wiley & Sons, New York
44. Cariello, N. F., Piegorsch, W. W., Adams, W. T., and Skopek, T. R. (1994) Carcinogenesis 15, 2281-2285
45. Cariello, N. F., Douglas, G. R., Gorelick, N. J., Hart, D. W., Wilson, J. D., and Soussi, T. (1998) Nucleic Acids Res. 26, 198-199
46. Pfeifer, G. P., Drouin, R., and Holmquist, G. P. (1993) Mutation Res. 288, 39-46
47. Szabó, P. E., Pfeifer, G. P., Mann, J. R., and Singer-Sam, J. (1996) in Technologies for Detection of DNA Damage and Mutations (Pfeifer, G. P., ed) pp. 343-349, Plenum Press, New York
48. Dai, S. M., Chen, H. H., Chang, C., Riggs, A. D., and Flanagan, S. D. (2000) Nat. Biotechnol. 18, 1108-1111
49. Ambrose, B. J. B., and Pless, R. C. (1985) Biochemistry 24, 6194-6200
50. Ambrose, B. J. B., Pless, R. C., and Ayers, M. E. (1988) Anal. Biochem. 169, 151-158
51. Pfeifer, G. P., and Holmquist, G. P. (1997) Biochim. Biophys. Acta 1333, M1-M8
52. Richardson, F. C., and Richardson, K. K. (1990) Mutat. Res. 233, 127-138
53. Muench, K. F., Misra, R. P., and Humayun, M. Z. (1983) Proc. Natl. Acad. Sci. U. S. A. 80, 6-10
54. Wurdeman, R. L., Church, K. M., and Gold, B. (1989) J. Am. Chem. Soc. 111, 6408-6412
55. Said, B., and Shank, R. C. (1991) Nucleic Acids Res. 19, 1311-1316
56. Benasutti, M., Ejadi, S., Whitlow, M. D., and Loechler, E. L. (1988) Biochemistry 27, 472-481
57. Hurley, L. H., and Needham-VanDevanter, D. R. (1986) Acct. Chem. Res. 19, 230-237
58. Cloutier, J. F., Castonguay, A., O'Connor, T. R., and Drouin, R. (2001) J. Mol. Biol. 306, 169-188
59. Groopman, J. D., Croy, R. G., and Wogan, G. N. (1981) Proc. Natl. Acad. Sci. U. S. A. 78, 5445-5449
60. Tretyakova, N. Y., Niles, J. C., Burney, S., Wishnok, J. S., and Tannenbaum, S. R. (1999) Chem. Res. Toxicol. 12, 459-466
61. You, Y. H., and Pfeifer, G. P. (2001) J. Mol. Biol. 305, 389-399
62. Holmquist, G. P., and Gao, S. (1996) Mutat. Res. 386, 69-101
63. Hatahet, Z., Zhou, M., Reha-Krantz, L. J., Morrical, S. W., and Wallace, S. S. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 8556-8561
64. Vaisman, A., Frank, E. G., Iwai, S., Ohashi, E., Ohmori, H., Hanaoka, F., and Woodgate, R. (2003) DNA Repair (Amsterdam) 2, 991-1006
65. Suo, Z., and Johnson, K. A. (1998) J. Biol. Chem. 273, 27259-27267
66. Sagher, D., and Strauss, B. (1983) Biochemistry 22, 4518-4526
67. Kim, M.-S., and Guengerich, F. P. (1998) Chem. Res. Toxicol. 11, 311-316
68. Tornaletti, S., Rozek, D., and Pfeifer, G. P. (1993) Oncogene 8, 2051-2057
69. Pfeifer, G. P., and Denissenko, M. F. (1998) Environ. Mol. Mutagenesis 31, 197-205
70. Denissenko, M. F., Pao, A., Pfeifer, G. P., and Tang, M. (1998) Oncogene 16, 1241-1247
71. Hainaut, P., and Pfeifer, G. P. (2001) Carcinogenesis 22, 367-374
72. Yoon, J. H., Lee, C. S., and Pfeifer, G. P. (2003) Carcinogenesis 24, 113-119
73. Wei, S. J. C., Chang, R. L., Bhachech, N., Cui, X. X., Merkler, K. A., Wong, C. Q., Hennig, E., Yagi, H., Jerina, D. M., and Conney, A. H. (1993) Cancer Res. 53, 3294-3301
74. Wei, S. J. C., Chang, R. L., Cui, X. X., Merkler, K. A., Wong, C. Q., Yagi, H., Jerina, D. M., and Conney, A. H. (1996) Cancer Res. 56, 3695-3703
75. Schiltz, M., Cui, X. X., Lu, Y.-P., Yagi, H., Jerina, D. M., Zdzienicka, M. Z., Chang, R. L., Conney, A. H., and Wei, S. J. C. (1999) Carcinogenesis 20, 2279-2285
76. Bailey, E. A., Iyer, R. S., Stone, M. P., Harris, T. M., and Essigmann, J. M. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 1535-1539
77. Lawley, P. D. (1984) in Chemical Carcinogens (Searle, C. E., ed), 2nd Ed., pp. 324-484, American Chemical Society, Washington, D. C.
78. Persmark, M., and Guengerich, F. P. (1994) Biochemistry 33, 8662-8672
79. Watson, J. D., and Crick, F. H. C. (1953) Nature 171, 964-967
80. Topal, M. D., and Fresco, J. R. (1976) Nature 263, 285-289
81. Colominas, C., Luque, F. J., and Orozco, M. (1996) J. Am. Chem. Soc. 118, 6811-6821
82. Lawley, P. D., and Brookes, P. (1961) Nature 192, 1081-1082
83. Kierdaszuk, B., Johansson, C., Drakenberg, T., Stolarski, R., and Shugar, D. (1993) Biophys. Chem. 46, 207-215
84. Suen, W., Spiro, T. G., Sowers, L. C., and Fresco, J. R. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 4500-4505