메뉴 건너뛰기




Volumn 9, Issue 4, 1999, Pages 267-276

Progession as exemplified by human astrocytic tumors

Author keywords

Cell cycle; Gliomas; Oncogenes; Supressor genes

Indexed keywords

PROTEIN P53;

EID: 0032587217     PISSN: 1044579X     EISSN: None     Source Type: Journal    
DOI: 10.1006/scbi.1999.0132     Document Type: Article
Times cited : (49)

References (82)
  • 2
    • 0024437036 scopus 로고
    • Supratentorial anaplastic gliomas in adults. The prognostic importance of extent of resection and prior low-grade glioma
    • Winger MJ, Macdonald DR, Cairncross JG. Supratentorial anaplastic gliomas in adults. The prognostic importance of extent of resection and prior low-grade glioma. J Neurosurg. 71:1989;487-493.
    • (1989) J Neurosurg , vol.71 , pp. 487-493
    • Winger, M.J.1    MacDonald, D.R.2    Cairncross, J.G.3
  • 3
    • 0023708370 scopus 로고
    • Clonal genomic alterations in glioma malignancy stages
    • James CD, Carlbom E, Dumanski JP, et al. Clonal genomic alterations in glioma malignancy stages. Cancer Res. 48:1988;5546-5551.
    • (1988) Cancer Res , vol.48 , pp. 5546-5551
    • James, C.D.1    Carlbom, E.2    Dumanski, J.P.3    et at4
  • 4
    • 0027407245 scopus 로고
    • Subsets of glioblastoma multiforme defined by molecular genetic analysis
    • von Deimling A, von Ammon K, Schoenfeld D, et al. Subsets of glioblastoma multiforme defined by molecular genetic analysis. Brain Path. 3:1993;19-26.
    • (1993) Brain Path , vol.3 , pp. 19-26
    • Von, D.A.1    Von, A.K.2    Schoenfeld, D.3    Et, A.4
  • 5
    • 0029890378 scopus 로고    scopus 로고
    • Analysis of p53 mutation and epidermal growth factor receptor amplification in recurrent gliomas with malignant progression
    • Reifenberger J, Ring GU, Gies U, et al. Analysis of p53 mutation and epidermal growth factor receptor amplification in recurrent gliomas with malignant progression. J Neuropathol Exp Neurol. 55:1996;822-831.
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 822-831
    • Reifenberger, J.1    Ring, G.U.2    Gies, U.3    Et, A.4
  • 6
    • 0026728283 scopus 로고
    • Treatment and survival of low-grade astrocytoma in adults - 1977-1988
    • McCormack BM, Miller DC, Budzilovich GN, et al. Treatment and survival of low-grade astrocytoma in adults - 1977-1988. Neurosurgery. 31:1992;636.
    • (1992) Neurosurgery , vol.31 , pp. 636
    • McCormack, B.M.1    Miller, D.C.2    Budzilovich, G.N.3    Et, A.4
  • 7
    • 0027245492 scopus 로고
    • Influence of location and extent of surgical resection on survival of patients with glioblastoma multiforme: Results of three consecutive Radiation Therapy Oncology Group (RTOG) clinical trials
    • Simpson JR, Horton J, Scott C, et al. Influence of location and extent of surgical resection on survival of patients with glioblastoma multiforme: results of three consecutive Radiation Therapy Oncology Group (RTOG) clinical trials. Int J Rad Oncol, Biol, Phys. 26:1993;239-244.
    • (1993) Int J Rad Oncol, Biol, Phys , vol.26 , pp. 239-244
    • Simpson, J.R.1    Horton, J.2    Scott, C.3    Et, A.4
  • 8
    • 0029736825 scopus 로고    scopus 로고
    • Characterization of genomic alterations associated with glioma progression by comparative genomic hybridization
    • Weber RG, Sabel M, Reifenberger J, et al. Characterization of genomic alterations associated with glioma progression by comparative genomic hybridization. Oncogene. 13:1996;983-994.
    • (1996) Oncogene , vol.13 , pp. 983-994
    • Weber, R.G.1    Sabel, M.2    Reifenberger, J.3    Et, A.4
  • 9
    • 84949655795 scopus 로고
    • Cerebral astrocytomas and their derivatives
    • Scherer HJ. Cerebral astrocytomas and their derivatives. Am J Cancer. 40:1940;159-198.
    • (1940) Am J Cancer , vol.40 , pp. 159-198
    • Scherer, H.J.1
  • 10
    • 0021130259 scopus 로고
    • Patterns of the early gross chromosomal changes in malignant human gliomas
    • Bigner SH, Mark J, Mahaley JMS, et al. Patterns of the early gross chromosomal changes in malignant human gliomas. Hereditas. 101:1984;103-113.
    • (1984) Hereditas , vol.101 , pp. 103-113
    • Bigner, S.H.1    Mark, J.2    Mahaley, J.M.S.3    Et, A.4
  • 12
    • 0021273420 scopus 로고
    • Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
    • Ullrich A, Coussens L, Hayflick JS, et al. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature. 309:1984;418-425.
    • (1984) Nature , vol.309 , pp. 418-425
    • Ullrich, A.1    Coussens, L.2    Hayflick, J.S.3    Et, A.4
  • 14
    • 0024616344 scopus 로고
    • Loss of heterozygosity on chromosome 10 in human glioblastoma multiforme
    • Fujimoto M, Fults DW, Thomas GA, et al. Loss of heterozygosity on chromosome 10 in human glioblastoma multiforme. Genomics. 4:1989;210-214.
    • (1989) Genomics , vol.4 , pp. 210-214
    • Fujimoto, M.1    Fults, D.W.2    Thomas, G.A.3    Et, A.4
  • 15
    • 0030957897 scopus 로고    scopus 로고
    • Classification and grading of low-grade astrocytic tumors in children
    • Giannini C, Scheithauer BW. Classification and grading of low-grade astrocytic tumors in children. Brain Pathol. 7:1997;785-798.
    • (1997) Brain Pathol , vol.7 , pp. 785-798
    • Giannini, C.1    Scheithauer, B.W.2
  • 16
    • 0029083997 scopus 로고
    • Chromosomal abnormalities in 47 pediatric brain tumors
    • Agamanolis DP, Malone JM. Chromosomal abnormalities in 47 pediatric brain tumors. Cancer Genet Cytogene. 81:1995;125-134.
    • (1995) Cancer Genet Cytogene , vol.81 , pp. 125-134
    • Agamanolis, D.P.1    Malone, J.M.2
  • 19
    • 0025143557 scopus 로고
    • Loss of genetic information in central nervous system tumors common to children and young adults
    • James CD, He J, Carlbom E, et al. Loss of genetic information in central nervous system tumors common to children and young adults. Genes Chromosome Cancer. 2:1990;94-102.
    • (1990) Genes Chromosome Cancer , vol.2 , pp. 94-102
    • James, C.D.1    He, J.2    Carlbom, E.3    Et, A.4
  • 20
    • 0026676710 scopus 로고
    • Cytogenetic and loss of heterozygosity studies in ependymomas, pilocytic astrocytomas, and oligodendrogliomas
    • Ransom DT, Ritland SR, Kimmel DW, et al. Cytogenetic and loss of heterozygosity studies in ependymomas, pilocytic astrocytomas, and oligodendrogliomas. Genes Chromosom Cancer. 5:1992;348-356.
    • (1992) Genes Chromosom Cancer , vol.5 , pp. 348-356
    • Ransom, D.T.1    Ritland, S.R.2    Kimmel, D.W.3    Et, A.4
  • 21
    • 0029150548 scopus 로고
    • Non-random chromosomal gains in pilocytic astrocytomas of childhood
    • White FV, Anthony DC, Yunis EJ, et al. non-random chromosomal gains in pilocytic astrocytomas of childhood. Hum Pathol. 26:1995;979-986.
    • (1995) Hum Pathol , vol.26 , pp. 979-986
    • White, F.V.1    Anthony, D.C.2    Yunis, E.J.3    Et, A.4
  • 22
    • 0032527870 scopus 로고    scopus 로고
    • Are juvenile pilocytic astrocytomas benign tumors? A cytogenetic study in 24 cases
    • Zattara-Cannoni H, Gambarelli D, Lena G, et al. Are juvenile pilocytic astrocytomas benign tumors? A cytogenetic study in 24 cases. Cancer Genet Cytogen. 104:1998;157-160.
    • (1998) Cancer Genet Cytogen , vol.104 , pp. 157-160
    • Zattara-Cannoni, H.1    Gambarelli, D.2    Lena, G.3    Et, A.4
  • 23
    • 0030005402 scopus 로고    scopus 로고
    • P53 gene mutations in human astrocytic brain tumors including pilocytic astrocytomas
    • Patt S, Gries H, Giraldo M, et al. p53 gene mutations in human astrocytic brain tumors including pilocytic astrocytomas. Hum Pathol. 27:1996;586-589.
    • (1996) Hum Pathol , vol.27 , pp. 586-589
    • Patt, S.1    Gries, H.2    Giraldo, M.3    Et, A.4
  • 24
    • 0027305401 scopus 로고
    • Deletions on the long arm of chromosome 17 in pilocytic astrocytoma
    • von Deimling A, Louis DN, Menon AG et al. Deletions on the long arm of chromosome 17 in pilocytic astrocytoma. Acta Neuropathol (Berl). 86:1993;81-85.
    • (1993) Acta Neuropathol (Berl) , vol.86 , pp. 81-85
    • Von Deimling, A.1    Louis, D.N.2    Menon, A.G.3
  • 25
    • 0030017285 scopus 로고    scopus 로고
    • Up-regulation of specific NF 1 gene transcripts in sporadic pilocytic astrocytomas
    • Platten M, Giordano MJ, Dirven CM, et al. Up-regulation of specific NF 1 gene transcripts in sporadic pilocytic astrocytomas. Am J Pathol. 149:1996;621-627.
    • (1996) Am J Pathol , vol.149 , pp. 621-627
    • Platten, M.1    Giordano, M.J.2    Dirven, C.M.3    Et, A.4
  • 26
    • 0026520151 scopus 로고
    • Prognostic value of cytogenetic analysis in human cerebral astrocytomas
    • Kimmel DW, O'Fallon JR, Scheithauer BW, et al. Prognostic value of cytogenetic analysis in human cerebral astrocytomas. Ann Neurol. 31:1992;534-542.
    • (1992) Ann Neurol , vol.31 , pp. 534-542
    • Kimmel, D.W.1    O'Fallon, J.R.2    Scheithauer, B.W.3    Et, A.4
  • 27
    • 0038726748 scopus 로고
    • Loss of distinct regions on the short arm of chromosome 17 associated with tumorigenesis of human astrocytomas
    • el-Azouzi M, Chung RY, Farmer GE, et al. Loss of distinct regions on the short arm of chromosome 17 associated with tumorigenesis of human astrocytomas. Proc Natl Acad Sci USA. 86:1989;7186-7190.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 7186-7190
    • El-Azouzi, M.1    Chung, R.Y.2    Farmer, G.E.3    Et, A.4
  • 28
    • 0025187735 scopus 로고
    • Allelotype of human malignant astrocytoma
    • Fults D, Pedone CA, Thomas GA, et al. Allelotype of human malignant astrocytoma. Cancer Res. 50:1990;5784-5789.
    • (1990) Cancer Res , vol.50 , pp. 5784-5789
    • Fults, D.1    Pedone, C.A.2    Thomas, G.A.3    Et, A.4
  • 29
    • 0026547577 scopus 로고
    • P53 mutation and loss of heterozygosity on chromosomes 17 and 10 during human astrocytoma progression
    • Fults D, Brockmeyer D, Tullous MW, et al. p53 mutation and loss of heterozygosity on chromosomes 17 and 10 during human astrocytoma progression. Cancer Res. 52:1992;674-679.
    • (1992) Cancer Res , vol.52 , pp. 674-679
    • Fults, D.1    Brockmeyer, D.2    Tullous, M.W.3    Et, A.4
  • 30
    • 0026563318 scopus 로고
    • Loss of heterozygosity on the short arm of chromosome 17 in human astrocytomas
    • Wu JK, Darras BT. Loss of heterozygosity on the short arm of chromosome 17 in human astrocytomas. Neurol Res. 14:1992;39-44.
    • (1992) Neurol Res , vol.14 , pp. 39-44
    • Wu, J.K.1    Darras, B.T.2
  • 31
    • 0026629404 scopus 로고
    • P53 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma
    • von Deimling A, Eibl RH, Ohgaki H, et al. p53 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma. Cancer Res. 52:1992;2987-2990.
    • (1992) Cancer Res , vol.52 , pp. 2987-2990
    • Von, D.A.1    Eibl, R.H.2    Ohgaki, H.3    Et, A.4
  • 32
    • 0027430022 scopus 로고
    • Mutations of the p53 tumor suppressor gene in neoplasms of the human nervous system
    • Ohgaki H, Eibl RH, Schwab M, et al. Mutations of the p53 tumor suppressor gene in neoplasms of the human nervous system. Molec Carcinogen. 8:1993;74-80.
    • (1993) Molec Carcinogen , vol.8 , pp. 74-80
    • Ohgaki, H.1    Eibl, R.H.2    Schwab, M.3    Et, A.4
  • 33
    • 0028198314 scopus 로고
    • Alterations of the TP53 gene in human gliomas
    • Rasheed, BK, McLendon RE, Herndon JE, et al. Alterations of the TP53 gene in human gliomas. Cancer Res. 54:1994;1324-1330.
    • (1994) Cancer Res , vol.54 , pp. 1324-1330
    • Rasheed1    Bk2    McLendon, R.E.3    Herndon, J.E.4    Et, A.5
  • 34
    • 0027975755 scopus 로고
    • TP53 alterations and clinical outcome in low grade astrocytomas
    • Kraus JA, Bolln C, Wolf HK, et al. TP53 alterations and clinical outcome in low grade astrocytomas. Genes Chromosom Cancer. 10:1994;143-149.
    • (1994) Genes Chromosom Cancer , vol.10 , pp. 143-149
    • Kraus, J.A.1    Bolln, C.2    Wolf, H.K.3    Et, A.4
  • 35
    • 0028348219 scopus 로고
    • Evidence of allelic imbalance of chromosome 6 in human astrocytomas [published erratum appears in Neurology 1994 44(6):1190]
    • Liang BC, Ross DA, Greenberg HS, et al. Evidence of allelic imbalance of chromosome 6 in human astrocytomas [published erratum appears in Neurology 1994 44(6):1190]. Neurology. 44:1994;533-536.
    • (1994) Neurology , vol.44 , pp. 533-536
    • Liang, B.C.1    Ross, D.A.2    Greenberg, H.S.3    Et, A.4
  • 36
    • 0029736653 scopus 로고    scopus 로고
    • Human glioblastomas with no alterations of the CDKN2A (p16INK4a, MTS1) and CDK4 genes have frequent mutations of the retinoblastoma gene
    • Ichimura K, Schmidt EE, Goike HM, et al. Human glioblastomas with no alterations of the CDKN2A (p16INK4a, MTS1) and CDK4 genes have frequent mutations of the retinoblastoma gene. Oncogene. 13:1996;1065-1072.
    • (1996) Oncogene , vol.13 , pp. 1065-1072
    • Ichimura, K.1    Schmidt, E.E.2    Goike, H.M.3    Et, A.4
  • 37
    • 0031967883 scopus 로고    scopus 로고
    • Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades
    • Ichimura K, Schmidt EE, Miyakawa A, et al. Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades. Genes Chromosome Cancer. 1998.
    • (1998) Genes Chromosome Cancer
    • Ichimura, K.1    Schmidt, E.E.2    Miyakawa, A.3    Et, A.4
  • 38
    • 0028928886 scopus 로고
    • Analysis of the NF2 tumor-suppressor gene and of chromosome 22 deletions in gliomas
    • Hoang-Xuan K, Merel P, Vega F, et al. Analysis of the NF2 tumor-suppressor gene and of chromosome 22 deletions in gliomas. Int J Cancer. 60:1995;478-481.
    • (1995) Int J Cancer , vol.60 , pp. 478-481
    • Hoang-Xuan, K.1    Merel, P.2    Vega, F.3    Et, A.4
  • 39
    • 0031012306 scopus 로고    scopus 로고
    • Infrequent methylation of CDKN2A(MTS1/p16) and rare mutation of both CDKN2A and CDKN2B(MTS2/p15) in primary astrocytic tumours
    • Schmidt EE, Ichimura K, Messerle KR, et al. Infrequent methylation of CDKN2A(MTS1/p16) and rare mutation of both CDKN2A and CDKN2B(MTS2/p15) in primary astrocytic tumours. Br J Cancer. 75:1997;2-8.
    • (1997) Br J Cancer , vol.75 , pp. 2-8
    • Schmidt, E.E.1    Ichimura, K.2    Messerle, K.R.3    Et, A.4
  • 40
    • 0028868217 scopus 로고
    • Amplification at 12q13-14 in human malignant gliomas is frequently accompanied by loss of heterozygosity at loci proximal and distal to the amplification site
    • Reifenberger G, Reifenberger J, Ichimura K, et al. Amplification at 12q13-14 in human malignant gliomas is frequently accompanied by loss of heterozygosity at loci proximal and distal to the amplification site. Cancer Res. 55:1995;731-734.
    • (1995) Cancer Res , vol.55 , pp. 731-734
    • Reifenberger, G.1    Reifenberger, J.2    Ichimura, K.3    Et, A.4
  • 41
    • 0025790916 scopus 로고
    • Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo
    • Ekstrand AJ, James CD, Cavenee WK, et al. Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res. 51:1991;2164-2172.
    • (1991) Cancer Res , vol.51 , pp. 2164-2172
    • Ekstrand, A.J.1    James, C.D.2    Cavenee, W.K.3    Et, A.4
  • 42
    • 0026620656 scopus 로고
    • Correlation of cytogenetic analysis and loss of heterozygosity studies in human diffuse astrocytomas and mixed oligo-astrocytomas
    • Ransom, DT, Ritland SR, Moertel CA, et al. Correlation of cytogenetic analysis and loss of heterozygosity studies in human diffuse astrocytomas and mixed oligo-astrocytomas. Genes Chromosom Cancer. 5:1992;357-374.
    • (1992) Genes Chromosom Cancer , vol.5 , pp. 357-374
    • Ransom1    Dt2    Ritland, S.R.3    Moertel, C.A.4    Et, A.5
  • 43
    • 0028232183 scopus 로고
    • Comparative genomic hybridization of human malignant gliomas reveals multiple amplification sites and non-random chromosomal gains and losses
    • Schröck E, Thiel G, Lozanova T, et al. Comparative genomic hybridization of human malignant gliomas reveals multiple amplification sites and non-random chromosomal gains and losses. Am J Pathol. 144:1994;1203-1218.
    • (1994) Am J Pathol , vol.144 , pp. 1203-1218
    • Schröck, E.1    Thiel, G.2    Lozanova, T.3    Et, A.4
  • 44
    • 0032475878 scopus 로고    scopus 로고
    • Signaling to p53: Breaking the MDM2-p53 circuit
    • Prives C. Signaling to p53: breaking the MDM2-p53 circuit. Cell. 95:1998;5-8.
    • (1998) Cell , vol.95 , pp. 5-8
    • Prives, C.1
  • 45
    • 0027978368 scopus 로고
    • Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: Preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2
    • Reifenberger G, Reifenberger J, Ichimura K, et al. Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2. Cancer Res. 54:1994;4299-4303.
    • (1994) Cancer Res , vol.54 , pp. 4299-4303
    • Reifenberger, G.1    Reifenberger, J.2    Ichimura, K.3    Et, A.4
  • 46
    • 0029800810 scopus 로고    scopus 로고
    • Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets
    • Reifenberger G, Ichimura K, Reifenberger J, et al. Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets. Cancer Res. 56:1996;5141-5145.
    • (1996) Cancer Res , vol.56 , pp. 5141-5145
    • Reifenberger, G.1    Ichimura, K.2    Reifenberger, J.3    Et, A.4
  • 47
    • 0023521410 scopus 로고
    • Chromosomal patterns in human malignant astrocytomas
    • Rey JA, Bello MJ, de Campos JM, et al. Chromosomal patterns in human malignant astrocytomas. Cancer Genet Cytogene. 29:1987;201-221.
    • (1987) Cancer Genet Cytogene , vol.29 , pp. 201-221
    • Rey, J.A.1    Bello, M.J.2    De, C.J.3    Et, A.4
  • 48
    • 0023857965 scopus 로고
    • Specific chromosomal abnormalities in malignant human gliomas
    • Bigner SH, Mark J, Burger PC, et al. Specific chromosomal abnormalities in malignant human gliomas. Cancer Res. 48:1988;405-411.
    • (1988) Cancer Res , vol.48 , pp. 405-411
    • Bigner, S.H.1    Mark, J.2    Burger, P.C.3    Et, A.4
  • 49
    • 0023914874 scopus 로고
    • Gene amplification in malignant human gliomas: Clinical and histopathologic aspects
    • Bigner SH, Burger PC, Wong AJ, et al. Gene amplification in malignant human gliomas: clinical and histopathologic aspects. J Neuropathol Exp Neurol. 47:1988;191-205.
    • (1988) J Neuropathol Exp Neurol , vol.47 , pp. 191-205
    • Bigner, S.H.1    Burger, P.C.2    Wong, A.J.3    Et, A.4
  • 50
    • 0025313045 scopus 로고
    • Cytogenetics of human brain tumors. [Review] [78 refs]
    • Bigner SH, Mark J, Bigner DD. Cytogenetics of human brain tumors. [Review] [78 refs]. Cancer Genet Cytogene. 47:1990;141-154.
    • (1990) Cancer Genet Cytogene , vol.47 , pp. 141-154
    • Bigner, S.H.1    Mark, J.2    Bigner, D.D.3
  • 51
    • 0029010921 scopus 로고
    • Detection of multiple gains and losses of genetic material in ten glioma cell lines by comparative genomic hybridization
    • Mohapatra G, Kim DH, Feuerstein BG. Detection of multiple gains and losses of genetic material in ten glioma cell lines by comparative genomic hybridization. Genes Chromosome Cancer. 13:1995;86-93.
    • (1995) Genes Chromosome Cancer , vol.13 , pp. 86-93
    • Mohapatra, G.1    Kim, D.H.2    Feuerstein, B.G.3
  • 52
    • 0027936274 scopus 로고
    • Oncogene amplification in human gliomas: A molecular cytogenetic analysis
    • Muleris M, Almeida A, Dutrillaux AM, et al. Oncogene amplification in human gliomas: a molecular cytogenetic analysis. Oncogene. 9:1994;2717-2722.
    • (1994) Oncogene , vol.9 , pp. 2717-2722
    • Muleris, M.1    Almeida, A.2    Dutrillaux, A.M.3    Et, A.4
  • 53
    • 0028652269 scopus 로고
    • CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas
    • Schmidt EE, Ichimura K, Reifenberger G, et al. CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas. Cancer Res. 54:1994;6321-6324.
    • (1994) Cancer Res , vol.54 , pp. 6321-6324
    • Schmidt, E.E.1    Ichimura, K.2    Reifenberger, G.3    Et, A.4
  • 54
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo A, Herman JG, Mao L, et al. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nature Med. 1:1995;686-692.
    • (1995) Nature Med , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Et, A.4
  • 55
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
    • Herman JG, Merlo A, Mao L, et al. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res. 55:1995;4525-4530.
    • (1995) Cancer Res , vol.55 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3    Et, A.4
  • 56
    • 0028875205 scopus 로고
    • Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • Gonzalez-Zulueta M, Bender CM, Yang AS, et al. Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res. 55:1995;4531-4535.
    • (1995) Cancer Res , vol.55 , pp. 4531-4535
    • Gonzalez-Zulueta, M.1    Bender, C.M.2    Yang, A.S.3    Et, A.4
  • 57
    • 0029967152 scopus 로고    scopus 로고
    • Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation
    • Costello JF, Berger MS, Huang HS, et al. Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation. Cancer Res. 56:1996;2405-2410.
    • (1996) Cancer Res , vol.56 , pp. 2405-2410
    • Costello, J.F.1    Berger, M.S.2    Huang, H.S.3    Et, A.4
  • 58
    • 0029959177 scopus 로고    scopus 로고
    • Hypermethylation of the CpG island of p16/CDKN2 correlates with gene inactivation in gliomas
    • Fueyo J, Gomez-Manzano C, Bruner JM, et al. Hypermethylation of the CpG island of p16/CDKN2 correlates with gene inactivation in gliomas. Oncogene. 13:1996;1615-1619.
    • (1996) Oncogene , vol.13 , pp. 1615-1619
    • Fueyo, J.1    Gomez-Manzano, C.2    Bruner, J.M.3    Et, A.4
  • 59
    • 0021932240 scopus 로고
    • Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
    • Libermann TA, Nusbaum HR, Razon N, et al. Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin. Nature. 313:1985;144-147.
    • (1985) Nature , vol.313 , pp. 144-147
    • Libermann, T.A.1    Nusbaum, H.R.2    Razon, N.3    Et, A.4
  • 60
    • 0025114687 scopus 로고
    • Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas
    • Sugawa N, Ekstrand AJ, James CD, et al. Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas. Proc Natl Acad Sci USA. 87:1990;8602-8606.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8602-8606
    • Sugawa, N.1    Ekstrand, A.J.2    James, C.D.3    Et, A.4
  • 61
    • 0026548240 scopus 로고
    • Structural alterations of the epidermal growth factor receptor gene in human gliomas
    • Wong AJ, Ruppert JM, Bigner SH, et al. Structural alterations of the epidermal growth factor receptor gene in human gliomas. Proc Natl Acad Sci USA. 89:1992;2965-2969.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 2965-2969
    • Wong, A.J.1    Ruppert, J.M.2    Bigner, S.H.3    Et, A.4
  • 62
    • 0025313141 scopus 로고
    • Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma
    • Humphrey PA, Wong AJ, Vogelstein B, et al. Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma. Proc Natl Acad Sci USA. 87:1990;4207-4211.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4207-4211
    • Humphrey, P.A.1    Wong, A.J.2    Vogelstein, B.3    Et, A.4
  • 63
    • 0028237507 scopus 로고
    • Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification
    • Ekstrand AJ, Longo N, Hamid ML, et al. Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification. Oncogene. 9:1994;2313-2320.
    • (1994) Oncogene , vol.9 , pp. 2313-2320
    • Ekstrand, A.J.1    Longo, N.2    Hamid, M.L.3    Et, A.4
  • 64
    • 0028146767 scopus 로고
    • A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity
    • Nishikawa R, Ji XD, Harmon RC, et al. A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity. Proc Natl Acad Sci USA. 91:1994;7727-7731.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7727-7731
    • Nishikawa, R.1    Ji, X.D.2    Harmon, R.C.3    Et, A.4
  • 65
    • 0026521394 scopus 로고
    • Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails
    • Ekstrand AJ, Sugawa N, James CD, et al. Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails. Proc Natl Acad Sci USA. 89:1992;4309-4313.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4309-4313
    • Ekstrand, A.J.1    Sugawa, N.2    James, C.D.3    Et, A.4
  • 66
    • 0027167694 scopus 로고
    • Deletion mapping of the long arm of chromosome 10 in glioblastoma multiforme
    • Fults D, Pedone C. Deletion mapping of the long arm of chromosome 10 in glioblastoma multiforme. Genes Chromosome Cancer. 7:1993;173-177.
    • (1993) Genes Chromosome Cancer , vol.7 , pp. 173-177
    • Fults, D.1    Pedone, C.2
  • 67
    • 0027208575 scopus 로고
    • Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10
    • Karlbom, AE, James CD, Boethius J, et al. Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10. Hum Genet. 92:1993;169-174.
    • (1993) Hum Genet , vol.92 , pp. 169-174
    • Karlbom1    Ae2    James, C.D.3    Boethius, J.4    Et, A.5
  • 69
    • 0029024891 scopus 로고
    • Chromosome 10 deletion mapping in human gliomas: A common deletion region in 10q25
    • Rasheed BK, McLendon RE, Friedman HS, et al. Chromosome 10 deletion mapping in human gliomas: a common deletion region in 10q25. Oncogene. 10:1995;2243-2246.
    • (1995) Oncogene , vol.10 , pp. 2243-2246
    • Rasheed, B.K.1    McLendon, R.E.2    Friedman, H.S.3    Et, A.4
  • 70
    • 0029984064 scopus 로고    scopus 로고
    • Loss of heterozygosity of chromosome 10p in human gliomas
    • Kimmelman AC, Ross DA, Liang BC. Loss of heterozygosity of chromosome 10p in human gliomas. Genomics. 34:1996;250-254.
    • (1996) Genomics , vol.34 , pp. 250-254
    • Kimmelman, A.C.1    Ross, D.A.2    Liang, B.C.3
  • 71
    • 0029992049 scopus 로고    scopus 로고
    • Deletion mapping of gliomas suggest the presence of two small regions for candidate tumor-suppressor genes in a 17-cM interval on chromosome 10q
    • Albarosa, R, Colombo BM, Roz L, et al. Deletion mapping of gliomas suggest the presence of two small regions for candidate tumor-suppressor genes in a 17-cM interval on chromosome 10q. Am J Hum Gene. 58:1996;1260-1267.
    • (1996) Am J Hum Gene , vol.58 , pp. 1260-1267
    • Albarosa, R.1    Colombo, B.M.2    Roz, L.3
  • 72
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer [see comments]
    • Li J, Yen C, Liaw D, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer [see comments]. Science. 275:1997;1943-1947.
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3    Et, A.4
  • 73
    • 17144436629 scopus 로고    scopus 로고
    • Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
    • Steck, PA, Pershouse MA, Jasser SA, et al. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Gene. 15:1997;356-362.
    • (1997) Nat Gene , vol.15 , pp. 356-362
    • Steck1    Pa2    Pershouse, M.A.3    Jasser, S.A.4    Et, A.5
  • 74
    • 0030837555 scopus 로고    scopus 로고
    • P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
    • Myers MP, Stolarov JP, Eng C, et al. P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci USA. 94:1997;9052-9057.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9052-9057
    • Myers, M.P.1    Stolarov, J.P.2    Eng, C.3    Et, A.4
  • 75
    • 0032506011 scopus 로고    scopus 로고
    • The lipid phosphatase a ctivity of PTEN is critical for its tumor supressor function
    • Myers MP, Pass I, Batty IH, et al. The lipid phosphatase a ctivity of PTEN is critical for its tumor supressor function. Proc Natl Acad Sci USA. 95:1998;13513-13518.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13513-13518
    • Myers, M.P.1    Pass, I.2    Batty, I.H.3    Et, A.4
  • 76
    • 0030817576 scopus 로고    scopus 로고
    • Pten Gene Mutations Are Seen In High-Grade But Not In Low-Grade Gliomas
    • Rasheed BKA, Stenzel TT, McLendon RE, et al. Pten Gene Mutations Are Seen In High-Grade But Not In Low-Grade Gliomas. Cancer Res. 57:1997;4187-4190.
    • (1997) Cancer Res , vol.57 , pp. 4187-4190
    • Rasheed, B.K.A.1    Stenzel, T.T.2    McLendon, R.E.3    Et, A.4
  • 77
    • 0030799909 scopus 로고    scopus 로고
    • Somatic Mutations Of Pten In Glioblastoma Multiforme
    • Wang SI, Puc J, Li J, et al. Somatic Mutations Of Pten In Glioblastoma Multiforme. Cancer Res. 57:1997;4183-4186.
    • (1997) Cancer Res , vol.57 , pp. 4183-4186
    • Wang, S.I.1    Puc, J.2    Li, J.3    Et, A.4
  • 79
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature. 366:1993;704-707.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 80
    • 0031583962 scopus 로고    scopus 로고
    • Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
    • Honda R, Tanaka H, Yasuda H. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett. 420:1997;25-27.
    • (1997) FEBS Lett , vol.420 , pp. 25-27
    • Honda, R.1    Tanaka, H.2    Yasuda, H.3
  • 81
    • 0032518917 scopus 로고    scopus 로고
    • Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein
    • Roth J, Dobbelstein M, Freedman DA, et al. Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. Embo J. 17:1998;554-564.
    • (1998) Embo J , vol.17 , pp. 554-564
    • Roth, J.1    Dobbelstein, M.2    Freedman, D.A.3    Et, A.4
  • 82
    • 0030034263 scopus 로고    scopus 로고
    • Clinically distinct subgroups of glioblastoma multiforme studied by comparative genomic hybridization
    • Weber RG, Sommer C, Albert FK, et al. Clinically distinct subgroups of glioblastoma multiforme studied by comparative genomic hybridization. Lab Invest. 74:1996;108-119.
    • (1996) Lab Invest , vol.74 , pp. 108-119
    • Weber, R.G.1    Sommer, C.2    Albert, F.K.3    Et, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.